Sequence Description Alias PCC hrr Kfl00061_0280 (at1g08260 : 1660.0) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 3320.0) & (original description: no original description) kfl00061_0280_v1.1 0.9878472193994855 1 Kfl00349_0050 (o48653|dpola_orysa : 1124.0) DNA polymerase alpha catalytic subunit (EC 2.7.7.7) - Oryza sativa (Rice) & (at5g67100 : 1019.0) Encodes the putative catalytic subunit of the DNA polymerase alpha. Interacts with genes involved in chromatin-mediated cellular memory. ICU2 genetically interacts with TERMINAL FLOWER2, the ortholog of HETEROCHROMATIN PROTEIN1 of animals and yeasts, and with the Polycomb group (PcG) gene CURLY LEAF. A number of regulatory genes were derepressed in the icu2-1 mutant, including genes associated with flowering time, floral meristem, and floral organ identity. Mutant has curled, involute leaves and causes early flowering.; INCURVATA2 (ICU2); FUNCTIONS IN: DNA-directed DNA polymerase activity; INVOLVED IN: negative regulation of flower development, leaf morphogenesis; LOCATED IN: nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134), Zinc finger, DNA-directed DNA polymerase, family B, alpha (InterPro:IPR015088), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved site (InterPro:IPR017964), DNA-directed DNA polymerase, family B (InterPro:IPR006172), DNA-directed DNA polymerase, family B, pol2 (InterPro:IPR004578); BEST Arabidopsis thaliana protein match is: DNA binding;nucleotide binding;nucleic acid binding;DNA-directed DNA polymerases;DNA-directed DNA polymerases (TAIR:AT5G63960.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 2038.0) & (original description: no original description) kfl00349_0050_v1.1 0.9675800659600571 13 Kfl00213_0030 (at1g04730 : 462.0) Necessary for sister chromatid cohesion. Acts in synergy with ETG1.; CHROMOSOME TRANSMISSION FIDELITY 18 (CTF18); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: sister chromatid cohesion; LOCATED IN: replication fork; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959); BEST Arabidopsis thaliana protein match is: replication factor C1 (TAIR:AT5G22010.1); Has 4018 Blast hits to 4006 proteins in 709 species: Archae - 400; Bacteria - 666; Metazoa - 673; Fungi - 766; Plants - 379; Viruses - 21; Other Eukaryotes - 1113 (source: NCBI BLink). & (reliability: 924.0) & (original description: no original description) kfl00213_0030_v1.1 0.9616189959863187 11 Kfl00109_0210 (at5g64630 : 397.0) Chromatin Assembly Factor-1 (CAF-1) p60 subunit. Involved in organization of the shoot and root apical meristems. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis.; FASCIATA 2 (FAS2); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat, conserved site (InterPro:IPR019775), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: homolog of histone chaperone HIRA (TAIR:AT3G44530.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (p93107|pf20_chlre : 84.0) Flagellar WD repeat protein PF20 - Chlamydomonas reinhardtii & (reliability: 794.0) & (original description: no original description) kfl00109_0210_v1.1 0.9543380565392893 14 Kfl00094_0200 (at5g52910 : 319.0) homolog of Drosophila timeless; TIMELESS (ATIM); CONTAINS InterPro DOMAIN/s: Timeless C-terminal (InterPro:IPR007725), Timeless protein (InterPro:IPR006906); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 638.0) & (original description: no original description) kfl00094_0200_v1.1 0.9468763861284129 23 Kfl00100_0250 (at1g67320 : 534.0) DNA primase, large subunit family; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, large subunit, eukaryotic (InterPro:IPR016558), DNA primase, large subunit, eukaryotic/archaeal (InterPro:IPR007238). & (reliability: 1068.0) & (original description: no original description) kfl00100_0250_v1.1 0.946719096111328 31 Kfl00108_0080 no hits & (original description: no original description) kfl00108_0080_v1.1 0.9462078632242364 29 Kfl00066_0340 (at3g42660 : 451.0) transducin family protein / WD-40 repeat family protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), WD40 repeat-like-containing domain (InterPro:IPR011046), Protein of unknown function DUF3639 (InterPro:IPR022100), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G23430.1); Has 41589 Blast hits to 20655 proteins in 706 species: Archae - 66; Bacteria - 8583; Metazoa - 14223; Fungi - 8894; Plants - 4578; Viruses - 3; Other Eukaryotes - 5242 (source: NCBI BLink). & (reliability: 902.0) & (original description: no original description) kfl00066_0340_v1.1 0.9459004709028964 29 Kfl00608_0090 (at5g61460 : 571.0) Encodes SMC6B (STRUCTURAL MAINTENANCE OF CHROMOSOMES 6B), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.; hypersensitive to MMS, irradiation and MMC (MIM); FUNCTIONS IN: ATP binding; INVOLVED IN: double-strand break repair, sister chromatid cohesion, chromosome segregation, response to X-ray, double-strand break repair via homologous recombination; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 6A (TAIR:AT5G07660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1142.0) & (original description: no original description) kfl00608_0090_v1.1 0.9449652512118782 22 Kfl00626_0050 (at3g18524 : 1095.0) Encodes a DNA mismatch repair homolog of human MutS gene, MSH6. MSH2 is involved in maintaining genome stability and repressing recombination of mismatched heteroduplexes.There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2 has different binding specificity to different mismatches in combination with MSH3, MSH6, or MSH7.; MUTS homolog 2 (MSH2); FUNCTIONS IN: damaged DNA binding, protein binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, negative regulation of reciprocal meiotic recombination; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein, MSH2 (InterPro:IPR011184); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1); Has 13560 Blast hits to 13453 proteins in 2654 species: Archae - 128; Bacteria - 8942; Metazoa - 734; Fungi - 813; Plants - 457; Viruses - 3; Other Eukaryotes - 2483 (source: NCBI BLink). & (q9xgc9|msh2_maize : 1091.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 2190.0) & (original description: no original description) kfl00626_0050_v1.1 0.9416224918448423 10 Kfl00049_0150 no hits & (original description: no original description) kfl00049_0150_v1.1 0.9414966026304472 11 Kfl00146_g3 no hits & (original description: no original description) kfl00146_g3_v1.1 0.9410398777680147 12 Kfl00072_0060 (at1g57820 : 631.0) Encodes a 645-amino acid methylcytosine-binding protein with a PHD domain, two RING finger domains, and an SRA domain that is involved in centromere heterochromatinization. This protein functions as an E3 ubiquitin ligase in vitro. The protein has been shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the former. It plays a role in the establishment/maintenance of chromatin structure during cell division and is localized in the nucleus. Plants over-expressing VIM1/ORTH2 show an inhibition in root growth and a delay in flowering. Both over-expression of GFP:ORTH2 and loss of ORTH2/VIM1 lead to decreased levels of DNA methylation. GFP:ORTH2 over-expressers also have increased levels of FWA transcripts.; VARIANT IN METHYLATION 1 (VIM1); CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), SRA-YDG (InterPro:IPR003105), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57800.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1262.0) & (original description: no original description) kfl00072_0060_v1.1, kfl00072_0060_v1.1 0.937452873499719 38 Kfl00007_0060 (at5g01630 : 307.0) Ortholog of breast cancer susceptibility protein 2. Essential at meiosis. Interacts with with both Rad51 and Dss1(I) or both Dmc1 and Dss1(I) in a tripartite complex.; BRCA2-like B (BRCA2B); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis; LOCATED IN: mitochondrion; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BREAST CANCER 2 like 2A (TAIR:AT4G00020.1); Has 281 Blast hits to 210 proteins in 91 species: Archae - 0; Bacteria - 4; Metazoa - 134; Fungi - 18; Plants - 61; Viruses - 0; Other Eukaryotes - 64 (source: NCBI BLink). & (reliability: 614.0) & (original description: no original description) kfl00007_0060_v1.1 0.936340156962435 20 Kfl00302_0030 (at1g67780 : 163.0) Zinc-finger domain of monoamine-oxidase A repressor R1 protein; CONTAINS InterPro DOMAIN/s: DDT domain superfamily (InterPro:IPR018501), DDT domain, subgroup (InterPro:IPR018500), Cell division cycle-associated protein (InterPro:IPR018866); BEST Arabidopsis thaliana protein match is: Zinc-finger domain of monoamine-oxidase A repressor R1 protein (TAIR:AT1G67270.1); Has 462 Blast hits to 453 proteins in 104 species: Archae - 0; Bacteria - 0; Metazoa - 139; Fungi - 73; Plants - 215; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink). & (reliability: 326.0) & (original description: no original description) kfl00302_0030_v1.1 0.9351794167476468 30 Kfl00181_0220 (at4g08990 : 1038.0) DNA (cytosine-5-)-methyltransferase family protein; FUNCTIONS IN: DNA binding, DNA (cytosine-5-)-methyltransferase activity; INVOLVED IN: DNA methylation; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: DNA (cytosine-5)-methyltransferase 1 (InterPro:IPR017198), DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), DNA methylase, C-5 cytosine-specific, active site (InterPro:IPR018117); BEST Arabidopsis thaliana protein match is: DNA methyltransferase 2 (TAIR:AT4G14140.1); Has 7214 Blast hits to 6137 proteins in 1440 species: Archae - 249; Bacteria - 4362; Metazoa - 525; Fungi - 274; Plants - 335; Viruses - 111; Other Eukaryotes - 1358 (source: NCBI BLink). & (q9axt8|cmt1_maize : 184.0) DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Chromomethylase 1) (Zea methyltransferase2) (Zmet2) (DNA cytosine methyltransferase MET2a) - Zea mays (Maize) & (reliability: 2076.0) & (original description: no original description) kfl00181_0220_v1.1 0.9351520454651003 43 Kfl00069_0130 (at5g22010 : 421.0) replication factor C1 (RFC1); FUNCTIONS IN: DNA clamp loader activity, nucleoside-triphosphatase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: DNA replication; LOCATED IN: DNA replication factor C complex, intracellular; CONTAINS InterPro DOMAIN/s: DNA replication factor RFC1, C-terminal (InterPro:IPR013725), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), DNA replication factor C, large subunit (InterPro:IPR012178), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT1G04730.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 842.0) & (original description: no original description) kfl00069_0130_v1.1 0.9348356316734191 17 Kfl00135_0100 (at5g41880 : 457.0) POLA3; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer, DNA replication; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, small subunit (InterPro:IPR002755), DNA primase, small subunit, eukaryotic/archaeal (InterPro:IPR014052); Has 510 Blast hits to 504 proteins in 249 species: Archae - 95; Bacteria - 0; Metazoa - 124; Fungi - 138; Plants - 44; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink). & (reliability: 914.0) & (original description: no original description) kfl00135_0100_v1.1 0.9326775940939726 21 Kfl00052_0340 (at5g22110 : 456.0) Encodes a protein with similarity to DNA polymerase epsilon subunit B an essential gene that is required for DNA replication. Homozygous mutants are embryo lethal. Expressed in meristematic , rapidly dividing regions.; DNA polymerase epsilon subunit B2 (DPB2); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding; INVOLVED IN: DNA replication, DNA-dependent DNA replication; LOCATED IN: epsilon DNA polymerase complex, nucleus; EXPRESSED IN: embryo, male gametophyte, apical meristem, female gametophyte; CONTAINS InterPro DOMAIN/s: DNA polymerase epsilon, subunit B (InterPro:IPR016266), DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 412 Blast hits to 394 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 125; Fungi - 144; Plants - 62; Viruses - 0; Other Eukaryotes - 81 (source: NCBI BLink). & (reliability: 912.0) & (original description: no original description) kfl00052_0340_v1.1 0.9326146956533644 27 Kfl00327_0060 (at4g32700 : 819.0) Encodes a homolog of Drosophila MUS308 and mammalian DNA polymerase, which prevent spontaneous or DNA damage-induced production of DNA double strand breaks. Two conserved functional domains: an N-terminal superfamily II DNA/RNA helicase domain and a C-terminal prokaryotic-type DNA polymerase I domain. Required for regulated cell division and differentiation in meristems. Mutant plants show morphological defects, such as short roots, serrated leaves, and fasciation, as well as defective patterns of cell division and differentiation in the meristem. Mutant plants had 2.5 to 4.5-fold higher expression of ATGR1, ATBRCA1 and RAD51 genes. TEB is required for normal progression of DNA replication and for correct expression of genes during development.; helicases;ATP-dependent helicases;nucleic acid binding;ATP binding;DNA-directed DNA polymerases;DNA binding; FUNCTIONS IN: in 6 functions; INVOLVED IN: regulation of gene expression, DNA replication, DNA recombination, photomorphogenesis; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA-directed DNA polymerase, family A, palm domain (InterPro:IPR001098), DNA/RNA helicase, C-terminal (InterPro:IPR001650), DNA polymerase A domain (InterPro:IPR002298), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: U5 small nuclear ribonucleoprotein helicase (TAIR:AT2G42270.1); Has 17628 Blast hits to 16579 proteins in 2941 species: Archae - 600; Bacteria - 7507; Metazoa - 1254; Fungi - 1190; Plants - 590; Viruses - 412; Other Eukaryotes - 6075 (source: NCBI BLink). & (reliability: 1638.0) & (original description: no original description) kfl00327_0060_v1.1 0.9318102879429644 20 Kfl00201_0050 no hits & (original description: no original description) kfl00201_0050_v1.1 0.9300931086748198 22 Kfl00323_0170 (at5g23240 : 148.0) DNAJ heat shock N-terminal domain-containing protein; FUNCTIONS IN: unfolded protein binding, heat shock protein binding; INVOLVED IN: protein folding; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Molecular chaperone, heat shock protein, Hsp40, DnaJ (InterPro:IPR015609), Heat shock protein DnaJ, N-terminal (InterPro:IPR001623), Heat shock protein DnaJ (InterPro:IPR003095); BEST Arabidopsis thaliana protein match is: DNAJ heat shock N-terminal domain-containing protein (TAIR:AT2G42750.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 296.0) & (original description: no original description) kfl00323_0170_v1.1 0.9264726333585823 22 Kfl00176_0100 (at5g58140 : 89.4) Membrane-bound protein serine/threonine kinase that functions as blue light photoreceptor in redundancy with PHO1. Involved in stomatal opening, chloroplast movement and phototropism. Mediates blue light-induced growth enhancements. PHOT1 and PHOT2 mediate blue light-dependent activation of the plasma membrane H+-ATPase in guard cell protoplasts. PHOT2 possesses two LOV (LOV1 and LOV2, for light-oxygen-voltage-sensing) domains involved in FMN-binding and a C-terminus forming a serine/threonine kinase domain. LOV2 acts as an inhibitor of phototropin kinase in the dark, and light cancels the inhibition through cysteine-FMN adduct formation. LOV1 in contrast acts as an attenuator of photoactivation. Localized to the Golgi apparatus under the induction of blue light.; phototropin 2 (PHOT2); FUNCTIONS IN: protein serine/threonine kinase activity, FMN binding, kinase activity, blue light photoreceptor activity; INVOLVED IN: in 7 processes; LOCATED IN: Golgi apparatus, plasma membrane, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PAC motif (InterPro:IPR001610), Protein kinase, ATP binding site (InterPro:IPR017441), PAS fold (InterPro:IPR013767), Serine/threonine-protein kinase domain (InterPro:IPR002290), PAS (InterPro:IPR000014), PAS-associated, C-terminal (InterPro:IPR000700), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719); BEST Arabidopsis thaliana protein match is: phototropin 1 (TAIR:AT3G45780.2); Has 25181 Blast hits to 21357 proteins in 1460 species: Archae - 236; Bacteria - 6754; Metazoa - 8411; Fungi - 2718; Plants - 3113; Viruses - 9; Other Eukaryotes - 3940 (source: NCBI BLink). & (q5z8k3|ado1_orysa : 87.0) Adagio-like protein 1 - Oryza sativa (Rice) & (reliability: 169.4) & (original description: no original description) kfl00176_0100_v1.1, kfl00176_0100_v1.1, kfl00176_0100_v1.1 0.9263083659154413 23 Kfl00302_0040 no hits & (original description: no original description) kfl00302_0040_v1.1 0.9192813682105053 52 Kfl00055_0170 (at3g57060 : 412.0) binding; FUNCTIONS IN: binding; INVOLVED IN: mitosis, chromosome condensation; LOCATED IN: nucleus, condensin complex; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Non-SMC condensin subunit, XCAP-D2/Cnd1 (InterPro:IPR007673), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: binding (TAIR:AT4G15890.1). & (reliability: 824.0) & (original description: no original description) kfl00055_0170_v1.1 0.9188513336005949 45 Kfl00376_0100 (q6es10|hat1_orysa : 137.0) Probable acetyltransferase type B catalytic subunit (EC 2.3.1.48) (HAT B) - Oryza sativa (Rice) & (at5g56740 : 130.0) Encodes an enzyme with histone acetyltransferase activity. Histone H4 is the primary substrate for the enzyme. Prior acetylation of lysine 12 of histone H4 reduces radioactive acetylation by HAG2. HAG2 acetylates histone H4 lysine 12.; histone acetyltransferase of the GNAT family 2 (HAG2); FUNCTIONS IN: histone acetyltransferase activity, H4 histone acetyltransferase activity; INVOLVED IN: histone acetylation, chromatin modification, chromatin silencing at telomere; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone acetyltransferase type B, catalytic subunit (InterPro:IPR017380), GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), Acyl-CoA N-acyltransferase (InterPro:IPR016181), Histone acetyl transferase HAT1 N-terminal (InterPro:IPR019467); Has 368 Blast hits to 368 proteins in 193 species: Archae - 0; Bacteria - 0; Metazoa - 119; Fungi - 147; Plants - 50; Viruses - 0; Other Eukaryotes - 52 (source: NCBI BLink). & (reliability: 260.0) & (original description: no original description) kfl00376_0100_v1.1 0.9184596528649343 26 Kfl01000_0010 no hits & (original description: no original description) kfl01000_0010_v1.1 0.9175654968361372 27 Kfl00080_0200 (at1g70210 : 131.0) Encodes a D-type cyclin that physically interacts with CDC2A. Its expression is upregulated early during germination.; CYCLIN D1;1 (CYCD1;1); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: G1 phase of mitotic cell cycle, regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin D (InterPro:IPR015451), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: Cyclin D2;1 (TAIR:AT2G22490.1); Has 3455 Blast hits to 3453 proteins in 343 species: Archae - 0; Bacteria - 0; Metazoa - 1586; Fungi - 382; Plants - 1073; Viruses - 13; Other Eukaryotes - 401 (source: NCBI BLink). & (reliability: 262.0) & (original description: no original description) kfl00080_0200_v1.1 0.9157351182834562 28 Kfl00014_0390 (at4g20325 : 186.0) FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Ribonuclease H2, subunit B (InterPro:IPR019024); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 372.0) & (original description: no original description) kfl00014_0390_v1.1 0.9157140558536339 49 Kfl00497_0060 no hits & (original description: no original description) kfl00497_0060_v1.1 0.9150822716170735 38 Kfl00031_0310 (at2g05210 : 102.0) Encodes AtPOT1a, an accessory factor for telomerase required for positive telomere length regulation. Note on nomenclature: different names have been given to Arabidopsis POT-like genes (Kuchar and Fajkus, 2004; Shakirov et al, 2005; Tani and Murata, 2005). According to a unifying nomenclature (Surovtseva et al, 2007), At2g05210 (previously named AtPOT1) is designated AtPOT1a, while At5g06310 (previously named AtPOT2) is designated AtPOT1b.; Protection of Telomeres 1a (AtPOT1a); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Telomere end binding protein (InterPro:IPR011564); BEST Arabidopsis thaliana protein match is: Nucleic acid-binding, OB-fold-like protein (TAIR:AT5G06310.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 204.0) & (original description: no original description) kfl00031_0310_v1.1 0.9143234208814977 55 Kfl00203_0160 (at1g10930 : 726.0) DNA helicase involved in the maintenance of genome stability by modulation of the DNA damage response and suppression of homologous recombination.; RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink). & (reliability: 1452.0) & (original description: no original description) kfl00203_0160_v1.1, kfl00203_0160_v1.1 0.9141616896824176 32 Kfl00033_0050 (at4g24710 : 451.0) P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; EXPRESSED IN: shoot apex, embryo, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, conserved site (InterPro:IPR003960), Chaperonin clpA/B (InterPro:IPR001270); BEST Arabidopsis thaliana protein match is: ATPase, AAA-type, CDC48 protein (TAIR:AT3G53230.1); Has 23595 Blast hits to 21814 proteins in 2884 species: Archae - 1432; Bacteria - 8057; Metazoa - 4130; Fungi - 3211; Plants - 2291; Viruses - 16; Other Eukaryotes - 4458 (source: NCBI BLink). & (reliability: 902.0) & (original description: no original description) kfl00033_0050_v1.1 0.9138086222885277 33 Kfl00110_0030 (at3g27640 : 283.0) Transducin/WD40 repeat-like superfamily protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT2G43770.1); Has 36714 Blast hits to 22017 proteins in 645 species: Archae - 42; Bacteria - 5151; Metazoa - 14249; Fungi - 8186; Plants - 4562; Viruses - 0; Other Eukaryotes - 4524 (source: NCBI BLink). & (reliability: 566.0) & (original description: no original description) kfl00110_0030_v1.1 0.9133527859055033 54 Kfl00422_0150 (at1g67630 : 373.0) DNA polymerase alpha 2 (POLA2); FUNCTIONS IN: DNA binding, DNA-directed DNA polymerase activity; INVOLVED IN: DNA replication; LOCATED IN: mitochondrion; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase alpha, subunit B N-terminal (InterPro:IPR013627), DNA polymerase alpha, subunit B (InterPro:IPR016722), DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 415 Blast hits to 412 proteins in 190 species: Archae - 0; Bacteria - 0; Metazoa - 175; Fungi - 140; Plants - 46; Viruses - 0; Other Eukaryotes - 54 (source: NCBI BLink). & (reliability: 746.0) & (original description: no original description) kfl00422_0150_v1.1 0.9117774944149009 42 Kfl00647_0040 (at3g48110 : 1020.0) glycine-tRNA ligase; EMBRYO-DEFECTIVE-DEVELOPMENT 1 (EDD1); FUNCTIONS IN: glycine-tRNA ligase activity; INVOLVED IN: regulation of embryonic development, glycyl-tRNA aminoacylation, embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal (InterPro:IPR002311), Glycyl-tRNA synthetase, class II, heterodimeric (InterPro:IPR006194), Glycyl-tRNA synthetase, class IIc, beta subunit (InterPro:IPR015944), Glycyl-tRNA synthetase, class IIc, alpha subunit (InterPro:IPR002310); Has 11308 Blast hits to 11293 proteins in 1754 species: Archae - 4; Bacteria - 6864; Metazoa - 4; Fungi - 1; Plants - 40; Viruses - 0; Other Eukaryotes - 4395 (source: NCBI BLink). & (reliability: 2040.0) & (original description: no original description) kfl00647_0040_v1.1 0.910528199435487 36 Kfl00340_0020 (at4g33680 : 587.0) Involved in disease resistance against Pseudomonas syringae. mutants have elevated SA levels, a low level of spontaneous cell death, callose deposition, and enlarged cells in leaves. genetically maps on chr 4 between L23H3 and nga1139.; ABERRANT GROWTH AND DEATH 2 (AGD2); FUNCTIONS IN: transaminase activity, copper ion binding, L,L-diaminopimelate aminotransferase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, systemic acquired resistance, salicylic acid mediated signaling pathway; LOCATED IN: chloroplast, chloroplast stroma; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: LL-diaminopimelate aminotransferase, plant-related (InterPro:IPR019942), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: AGD2-like defense response protein 1 (TAIR:AT2G13810.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1174.0) & (original description: no original description) kfl00340_0020_v1.1 0.9105052998342212 37 Kfl00050_0180 (at1g27880 : 512.0) DEAD/DEAH box RNA helicase family protein ; FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: DNA recombination; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEAD/DEAH box RNA helicase family protein (TAIR:AT4G35740.1); Has 41244 Blast hits to 39032 proteins in 2984 species: Archae - 762; Bacteria - 21282; Metazoa - 5401; Fungi - 4173; Plants - 3671; Viruses - 588; Other Eukaryotes - 5367 (source: NCBI BLink). & (reliability: 1024.0) & (original description: no original description) kfl00050_0180_v1.1 0.9093968044785801 38 Kfl00054_0235 (at5g42480 : 110.0) Shows homology to the cyanobacterial cell division protein Ftn2, mutant only has two mesophyll cell chloroplasts. Protein was localized to a ring at the center of the chloroplasts. Probably involved in functions in the assembly and/or stabilization of the plastid-dividing FtsZ ring, inhibiting FtsZ filament formation in the chloroplast.; ACCUMULATION AND REPLICATION OF CHLOROPLASTS 6 (ARC6); FUNCTIONS IN: protein binding; INVOLVED IN: protein folding, chloroplast fission, chloroplast organization; LOCATED IN: chloroplast, chloroplast inner membrane, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Heat shock protein DnaJ, N-terminal (InterPro:IPR001623); BEST Arabidopsis thaliana protein match is: paralog of ARC6 (TAIR:AT3G19180.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 220.0) & (original description: no original description) kfl00054_0235_v1.1 0.9090609381718755 39 Kfl00162_0010 (at3g02740 : 90.5) Eukaryotic aspartyl protease family protein; FUNCTIONS IN: aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: plasma membrane, anchored to membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase aspartic (InterPro:IPR021109), Peptidase aspartic, catalytic (InterPro:IPR009007), Peptidase A1 (InterPro:IPR001461), Peptidase aspartic, active site (InterPro:IPR001969); BEST Arabidopsis thaliana protein match is: Eukaryotic aspartyl protease family protein (TAIR:AT5G36260.1); Has 4403 Blast hits to 4392 proteins in 396 species: Archae - 0; Bacteria - 0; Metazoa - 1232; Fungi - 945; Plants - 1948; Viruses - 0; Other Eukaryotes - 278 (source: NCBI BLink). & (reliability: 181.0) & (original description: no original description) kfl00162_0010_v1.1 0.9087851457898175 40 Kfl00358_0060 (at3g52950 : 407.0) CBS / octicosapeptide/Phox/Bemp1 (PB1) domains-containing protein; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Octicosapeptide/Phox/Bem1p (InterPro:IPR000270), Cystathionine beta-synthase, core (InterPro:IPR000644); BEST Arabidopsis thaliana protein match is: CBS / octicosapeptide/Phox/Bemp1 (PB1) domains-containing protein (TAIR:AT2G36500.1). & (reliability: 814.0) & (original description: no original description) kfl00358_0060_v1.1 0.9071570560416385 41 Kfl00153_0160 (at4g02070 : 834.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.; MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). & (q9xgc9|msh2_maize : 175.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 1668.0) & (original description: no original description) kfl00153_0160_v1.1 0.9067353599947974 42 Kfl00043_0150 (at4g34570 : 494.0) Encodes a bifunctional dihydrofolate reductase - thymidylate synthase gene. This is unique in Arabidopsis and protozoa. Other organisms have independent genes for this function.; thymidylate synthase 2 (THY-2); CONTAINS InterPro DOMAIN/s: Thymidylate synthase, active site (InterPro:IPR020940), Dihydrofolate reductase domain (InterPro:IPR001796), Dihydrofolate reductase conserved site (InterPro:IPR017925), Bifunctional dihydrofolate reductase/thymidylate synthase (InterPro:IPR012262), Thymidylate synthase (InterPro:IPR000398); BEST Arabidopsis thaliana protein match is: thymidylate synthase 1 (TAIR:AT2G16370.1); Has 13567 Blast hits to 13544 proteins in 2627 species: Archae - 73; Bacteria - 8801; Metazoa - 517; Fungi - 428; Plants - 92; Viruses - 256; Other Eukaryotes - 3400 (source: NCBI BLink). & (o81395|drts_maize : 493.0) Bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] - Zea mays (Maize) & (reliability: 974.0) & (original description: no original description) kfl00043_0150_v1.1, kfl00043_0150_v1.1 0.9065134531053912 43 Kfl00567_0050 (at2g14050 : 705.0) minichromosome maintenance 9 (MCM9); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: DNA-dependent DNA replication initiation, DNA replication; LOCATED IN: cellular_component unknown; EXPRESSED IN: sperm cell, male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT1G44900.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q43704|mcm3_maize : 258.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1410.0) & (original description: no original description) kfl00567_0050_v1.1 0.9045890951504395 48 Kfl00756_0030 (at5g01920 : 242.0) Chloroplast thylakoid protein kinase STN8 is specific in phosphorylation of N-terminal threonine residues in D1, D2 and CP43 proteins, and Thr-4 in PsbH protein of photosystem II. Phosphorylation of Thr-4 in the wild type required both light and prior phosphorylation at Thr-2.; STN8; FUNCTIONS IN: protein kinase activity, kinase activity; INVOLVED IN: photosystem II stabilization; LOCATED IN: thylakoid, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, core (InterPro:IPR000719), Serine/threonine protein kinase-related (InterPro:IPR017442), Protein kinase-like (InterPro:IPR011009), Serine/threonine protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: STN7 (Stt7 homolog STN7); kinase/ protein kinase (TAIR:AT1G68830.1); Has 33057 Blast hits to 33030 proteins in 1682 species: Archae - 26; Bacteria - 4053; Metazoa - 14243; Fungi - 4538; Plants - 3212; Viruses - 96; Other Eukaryotes - 6889 (source: NCBI BLink). & (q84v18|stt7_chlre : 193.0) Serine/threonine-protein kinase stt7, chloroplast precursor (EC 2.7.11.1) - Chlamydomonas reinhardtii & (reliability: 484.0) & (original description: no original description) kfl00756_0030_v1.1 0.903684746011393 45 Kfl00086_0370 (at3g05740 : 520.0) RECQ helicase l1 (RECQI1); FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: DNA recombination; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DNA helicase (RECQl4A) (TAIR:AT1G10930.1); Has 22913 Blast hits to 22836 proteins in 2673 species: Archae - 358; Bacteria - 13443; Metazoa - 2936; Fungi - 2132; Plants - 1261; Viruses - 9; Other Eukaryotes - 2774 (source: NCBI BLink). & (reliability: 1040.0) & (original description: no original description) kfl00086_0370_v1.1 0.9033509361546528 46 Kfl00222_0100 (at5g37630 : 265.0) EMBRYO DEFECTIVE 2656 (EMB2656); FUNCTIONS IN: binding; INVOLVED IN: mitotic chromosome condensation, embryo development ending in seed dormancy; LOCATED IN: cellular_component unknown; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-type fold (InterPro:IPR016024); Has 333 Blast hits to 316 proteins in 147 species: Archae - 0; Bacteria - 4; Metazoa - 113; Fungi - 138; Plants - 47; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink). & (reliability: 530.0) & (original description: no original description) kfl00222_0100_v1.1 0.9019098003825397 65 Kfl00614_0020 (at3g13870 : 803.0) required for regulated cell expansion and normal root hair development. Encodes an evolutionarily conserved protein with putative GTP-binding motifs that is implicated in the control of vesicle trafficking between the endoplasmic reticulum and the Golgi compartments.; ROOT HAIR DEFECTIVE 3 (RHD3); FUNCTIONS IN: GTP binding; INVOLVED IN: root epidermal cell differentiation, plant-type cell wall biogenesis, ER to Golgi vesicle-mediated transport, actin cytoskeleton organization, cell tip growth; LOCATED IN: endoplasmic reticulum, plasma membrane, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Root hair defective 3 GTP-binding (InterPro:IPR008803); BEST Arabidopsis thaliana protein match is: Root hair defective 3 GTP-binding protein (RHD3) (TAIR:AT1G72960.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1606.0) & (original description: no original description) kfl00614_0020_v1.1 0.9010737059207254 48 Kfl00593_0080 (at1g08540 : 226.0) Enodes a subunit of chloroplast RNA polymerase, confers the ability to recognize promoter sequences on the core enzyme. SIG1 is induced by red and blue light.; RNApolymerase sigma subunit 2 (SIG2); CONTAINS InterPro DOMAIN/s: RNA polymerase sigma factor, region 2 (InterPro:IPR013325), Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), RNA polymerase sigma-70 region 3 (InterPro:IPR007624), RNA polymerase sigma-70 (InterPro:IPR014284), RNA polymerase sigma factor, region 3/4 (InterPro:IPR013324), RNA polymerase sigma-70 region 1.2 (InterPro:IPR009042), RNA polymerase sigma-70 factor (InterPro:IPR000943), RNA polymerase sigma factor, SigB/SigC/SigD, plastid (InterPro:IPR016262), RNA polymerase sigma-70 region 2 (InterPro:IPR007627), RNA polymerase sigma-70 region 4 (InterPro:IPR007630); BEST Arabidopsis thaliana protein match is: RNApolymerase sigma-subunit F (TAIR:AT2G36990.1); Has 24116 Blast hits to 24030 proteins in 2811 species: Archae - 0; Bacteria - 17119; Metazoa - 4; Fungi - 2; Plants - 243; Viruses - 12; Other Eukaryotes - 6736 (source: NCBI BLink). & (reliability: 452.0) & (original description: no original description) kfl00593_0080_v1.1 0.8999294878439619 49 Kfl00029_0090 no hits & (original description: no original description) kfl00029_0090_v1.1 0.8993110143881905 57 Kfl00062_0110 (at4g01160 : 99.8) BTB/POZ/Kelch-associated protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/Kelch-associated (InterPro:IPR011705), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: POZ/BTB containin G-protein 1 (TAIR:AT3G61600.2); Has 3481 Blast hits to 3463 proteins in 124 species: Archae - 0; Bacteria - 0; Metazoa - 3173; Fungi - 4; Plants - 136; Viruses - 49; Other Eukaryotes - 119 (source: NCBI BLink). & (reliability: 199.6) & (original description: no original description) kfl00062_0110_v1.1 0.899248133891147 56 Kfl00032_0360 (at3g56490 : 174.0) Encodes a protein that has adenylylsulfate sulfohydrolase activity (E.C. 3.6.2.1) in vitro.; HIS triad family protein 3 (HIT3); FUNCTIONS IN: protein kinase C binding, adenylylsulfatase activity, zinc ion binding; INVOLVED IN: sulfur metabolic process, purine ribonucleotide metabolic process; LOCATED IN: peroxisome, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histidine triad-like motif (InterPro:IPR011146), Histidine triad, conserved site (InterPro:IPR019808), Histidine triad (HIT) protein (InterPro:IPR001310), Histidine triad motif (InterPro:IPR011151); BEST Arabidopsis thaliana protein match is: HISTIDINE TRIAD NUCLEOTIDE-BINDING 2 (TAIR:AT1G31160.1); Has 7957 Blast hits to 7956 proteins in 2592 species: Archae - 148; Bacteria - 4849; Metazoa - 343; Fungi - 139; Plants - 127; Viruses - 0; Other Eukaryotes - 2351 (source: NCBI BLink). & (p42856|zb14_maize : 174.0) 14 kDa zinc-binding protein (Protein kinase C inhibitor) (PKCI) - Zea mays (Maize) & (reliability: 348.0) & (original description: no original description) kfl00032_0360_v1.1 0.8990194628949515 52 Kfl00130_0230 no hits & (original description: no original description) kfl00130_0230_v1.1 0.8989943325387657 65 Kfl00373_0040 (q9mum5|mind_mesvi : 261.0) Putative septum site-determining protein minD - Mesostigma viride & (at5g24020 : 219.0) Encodes a Ca2+ dependent ATPase required for correct positioning of the chloroplast division apparatus. Its ATPase activity is stimulated by AtMinE1, a topological specificity factor.; MIND; FUNCTIONS IN: calcium-dependent ATPase activity, protein binding, ATPase activity, protein homodimerization activity; INVOLVED IN: chloroplast fission; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Septum site-determining protein MinD (InterPro:IPR010223), Cobyrinic acid a,c-diamide synthase (InterPro:IPR002586); BEST Arabidopsis thaliana protein match is: IND1(iron-sulfur protein required for NADH dehydrogenase)-like (TAIR:AT4G19540.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 438.0) & (original description: no original description) kfl00373_0040_v1.1 0.8972357460018706 54 Kfl00858_0020 no hits & (original description: no original description) kfl00858_0020_v1.1 0.8956768720425575 55 Kfl00481_0090 (at4g02060 : 837.0) Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.; PROLIFERA (PRL); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 7 (InterPro:IPR008050); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1). & (q43704|mcm3_maize : 242.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1674.0) & (original description: no original description) kfl00481_0090_v1.1 0.8953471674462644 66 Kfl00682_0020 (q9lre5|dpod2_orysa : 384.0) DNA polymerase delta small subunit (EC 2.7.7.7) - Oryza sativa (Rice) & (at2g42120 : 378.0) DNA polymerase delta small subunit (POLD2); FUNCTIONS IN: DNA binding, DNA-directed DNA polymerase activity; INVOLVED IN: DNA replication; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 756.0) & (original description: no original description) kfl00682_0020_v1.1 0.8946492566712596 57 Kfl00220_0150 no hits & (original description: no original description) kfl00220_0150_v1.1 0.8941221035946643 58 Kfl00489_0040 (at2g21790 : 1267.0) encodes large subunit of ribonucleotide reductase involved in the production of deoxyribonucleoside triphosphates (dNTPs) for DNA replication and repair; ribonucleotide reductase 1 (RNR1); FUNCTIONS IN: ribonucleoside-diphosphate reductase activity, ATP binding; INVOLVED IN: response to cadmium ion, DNA replication, deoxyribonucleoside triphosphate biosynthetic process; LOCATED IN: ribonucleoside-diphosphate reductase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribonucleotide reductase large subunit, N-terminal (InterPro:IPR013509), Ribonucleoside-diphosphate reductase, alpha subunit (InterPro:IPR013346), ATP-cone (InterPro:IPR005144), Ribonucleotide reductase large subunit, C-terminal (InterPro:IPR000788), Ribonucleotide reductase R1 subunit, N-terminal (InterPro:IPR008926); Has 15326 Blast hits to 14804 proteins in 2790 species: Archae - 206; Bacteria - 6388; Metazoa - 177; Fungi - 215; Plants - 88; Viruses - 606; Other Eukaryotes - 7646 (source: NCBI BLink). & (reliability: 2534.0) & (original description: no original description) kfl00489_0040_v1.1 0.8940378319059006 77 Kfl00604_0080 no hits & (original description: no original description) kfl00604_0080_v1.1 0.892919236361826 60 Kfl00093_0040 (at3g57660 : 885.0) Encodes a subunit of RNA polymerase I (aka RNA polymerase A).; nuclear RNA polymerase A1 (NRPA1); FUNCTIONS IN: DNA-directed RNA polymerase activity, DNA binding, zinc ion binding; INVOLVED IN: transcription; LOCATED IN: nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RNA polymerase, N-terminal (InterPro:IPR006592), RNA polymerase, alpha subunit (InterPro:IPR000722), RNA polymerase Rpb1, domain 3 (InterPro:IPR007066), RNA polymerase Rpb1, domain 1 (InterPro:IPR007080), RNA polymerase Rpb1, domain 5 (InterPro:IPR007081), DNA-directed RNA pol I, largest subunit (InterPro:IPR015699), RNA polymerase Rpb1, domain 4 (InterPro:IPR007083); BEST Arabidopsis thaliana protein match is: nuclear RNA polymerase C1 (TAIR:AT5G60040.1); Has 39638 Blast hits to 28014 proteins in 7318 species: Archae - 983; Bacteria - 11101; Metazoa - 5787; Fungi - 2930; Plants - 6395; Viruses - 781; Other Eukaryotes - 11661 (source: NCBI BLink). & (p60288|rpoc1_phypa : 102.0) DNA-directed RNA polymerase beta' chain (EC 2.7.7.6) (PEP) (Plastid-encoded RNA polymerase beta' subunit) (RNA polymerase beta' subunit) - Physcomitrella patens (Moss) & (reliability: 1770.0) & (original description: no original description) kfl00093_0040_v1.1 0.8926864271878491 61 Kfl00066_0260 (at5g15920 : 686.0) Encodes SMC5 (STRUCTURAL MAINTENANCE OF CHROMOSOMES 5), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.; structural maintenance of chromosomes 5 (SMC5); FUNCTIONS IN: ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT5G61460.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1372.0) & (original description: no original description) kfl00066_0260_v1.1 0.8921052123253476 66 Kfl00418_0100 no hits & (original description: no original description) kfl00418_0100_v1.1 0.8917494279793479 71 Kfl00434_0080 (at4g08920 : 663.0) Encodes CRY1, a flavin-type blue-light photoreceptor with ATP binding and autophosphorylation activity. Functions in perception of blue / green ratio of light. The photoreceptor may be involved in electron transport. Mutant phenotype displays a blue light-dependent inhibition of hypocotyl elongation. Photoreceptor activity requires light-induced homodimerisation of the N-terminal CNT1 domains of CRY1. Involved in blue-light induced stomatal opening. The C-terminal domain of the protein undergoes a light dependent conformational change. Also involved in response to circadian rhythm. Mutants exhibit long hypocotyl under blue light and are out of phase in their response to circadian rhythm. CRY1 is present in the nucleus and cytoplasm. Different subcellular pools of CRY1 have different functions during photomorphogenesis of Arabidopsis seedlings.; cryptochrome 1 (CRY1); CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Cryptochrome/DNA photolyase, class 1 conserved site, C-terminal (InterPro:IPR018394), DNA photolyase, N-terminal (InterPro:IPR006050), Cryptochrome C-terminal (InterPro:IPR020978), DNA photolyase, FAD-binding/Cryptochrome, C-terminal (InterPro:IPR005101), Cryptochrome, plant (InterPro:IPR014134), Cryptochrome/DNA photolyase, class 1 (InterPro:IPR002081); BEST Arabidopsis thaliana protein match is: cryptochrome 2 (TAIR:AT1G04400.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (p40115|phr1_sinal : 592.0) Deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) (DNA photolyase) (Photoreactivating enzyme) - Sinapis alba (White mustard) (Brassica hirta) & (reliability: 1326.0) & (original description: no original description) kfl00434_0080_v1.1 0.8915430103431555 64 Kfl00009_0470 no hits & (original description: no original description) kfl00009_0470_v1.1 0.8910793562625595 65 Kfl00357_0110 (at5g52560 : 723.0) Encodes a protein with UTP:sugar 1-phosphate uridylyltransferase activity, which has been shown to use a wide range of substrates including glucose-1-P, galactose-1-P, xylose-1-P, arabinose-1-P and glucuronate-1-P. The enzyme was shown to require Mg2+ or Mn2+ for activity. Mutations in USP can lead to a complete loss of male fertility.; UDP-sugar pyrophosphorylase (USP); FUNCTIONS IN: in 6 functions; INVOLVED IN: in 6 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: UTP--glucose-1-phosphate uridylyltransferase (InterPro:IPR002618); BEST Arabidopsis thaliana protein match is: N-acetylglucosamine-1-phosphate uridylyltransferase 1 (TAIR:AT1G31070.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1446.0) & (original description: no original description) kfl00357_0110_v1.1 0.8905301520134572 93 Kfl00039_0170 (at2g32590 : 335.0) LOCATED IN: chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Barren (InterPro:IPR008418); Has 467 Blast hits to 447 proteins in 202 species: Archae - 0; Bacteria - 4; Metazoa - 147; Fungi - 168; Plants - 39; Viruses - 1; Other Eukaryotes - 108 (source: NCBI BLink). & (reliability: 670.0) & (original description: no original description) kfl00039_0170_v1.1 0.8904376897773412 87 Kfl00981_0030 (at2g34040 : 294.0) Apoptosis inhibitory protein 5 (API5); FUNCTIONS IN: binding; INVOLVED IN: anti-apoptosis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Apoptosis inhibitory 5 (InterPro:IPR008383), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: Apoptosis inhibitory protein 5 (API5) (TAIR:AT1G29030.1); Has 227 Blast hits to 217 proteins in 75 species: Archae - 0; Bacteria - 0; Metazoa - 144; Fungi - 6; Plants - 61; Viruses - 0; Other Eukaryotes - 16 (source: NCBI BLink). & (reliability: 588.0) & (original description: no original description) kfl00981_0030_v1.1 0.8903325416810377 68 Kfl00038_0280 no hits & (original description: no original description) kfl00038_0280_v1.1 0.8900957597933461 69 Kfl00213_0020 (at4g14385 : 114.0) FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Histone H4 acetyltransferase, NuA4 complex, Eaf6 (InterPro:IPR015418); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 228.0) & (original description: no original description) kfl00213_0020_v1.1 0.8889745940826141 70 Kfl00125_0020 (at2g13370 : 403.0) chromatin remodeling 5 (CHR5); FUNCTIONS IN: chromatin binding, helicase activity, DNA binding, nucleic acid binding, ATP binding; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin, nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chromo domain (InterPro:IPR000953), SNF2-related (InterPro:IPR000330), Homeodomain-like (InterPro:IPR009057), DEAD-like helicase, N-terminal (InterPro:IPR014001), Chromo domain-like (InterPro:IPR016197), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: chromatin remodeling factor CHD3 (PICKLE) (TAIR:AT2G25170.1); Has 38529 Blast hits to 28045 proteins in 2467 species: Archae - 189; Bacteria - 9973; Metazoa - 8887; Fungi - 6205; Plants - 2508; Viruses - 447; Other Eukaryotes - 10320 (source: NCBI BLink). & (q7g8y3|isw2_orysa : 384.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 776.0) & (original description: no original description) kfl00125_0020_v1.1, kfl00125_0020_v1.1, kfl00125_0020_v1.1 0.8884338825671138 71 Kfl00309_0170 (at5g63920 : 891.0) Encodes topoisomerase 3alpha. Suppresses somatic crossovers. Essential for resolution of meiotic recombination intermediates.; topoisomerase 3alpha (TOP3A); FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: in 7 processes; LOCATED IN: chromosome; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IA, zn finger (InterPro:IPR013498), DNA topoisomerase, type IA, core (InterPro:IPR000380), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, central (InterPro:IPR013497), Zinc finger, GRF-type (InterPro:IPR010666), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826), Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), Toprim domain (InterPro:IPR006171), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: DNA topoisomerase, type IA, core (TAIR:AT2G32000.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1782.0) & (original description: no original description) kfl00309_0170_v1.1 0.888180494147626 72 Kfl00116_0090 (at1g04020 : 184.0) Encodes a protein containing two tandem BRCA1 C-Terminal (BRCT) domains, which function in phosphorylation-dependent proteinñprotein interactions.Loss of function mutations cause defects in meristem organization due to failure to repress WUS. BARD1 binds to WUS promoter and over expression of BARD reduces the extent of WUS expression.; breast cancer associated RING 1 (BARD1); FUNCTIONS IN: transcription coactivator activity, DNA binding; INVOLVED IN: DNA repair, regulation of meristem structural organization, leaf development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer susceptibility1 (TAIR:AT4G21070.1); Has 6045 Blast hits to 5706 proteins in 320 species: Archae - 0; Bacteria - 47; Metazoa - 4577; Fungi - 362; Plants - 542; Viruses - 11; Other Eukaryotes - 506 (source: NCBI BLink). & (reliability: 354.0) & (original description: no original description) kfl00116_0090_v1.1, kfl00116_0090_v1.1 0.8879848726816433 87 Kfl00059_0230 (at5g61380 : 198.0) Pseudo response regulator involved in the generation of circadian rhythms. TOC1 appears to shorten the period of circumnutation speed. TOC1 contributes to the plant fitness (carbon fixation, biomass) by influencing the circadian clock period. PRR3 may increase the stability of TOC1 by preventing interactions between TOC1 and the F-box protein ZTL. Expression of TOC1 is correlated with rhythmic changes in chromatin organization.; TIMING OF CAB EXPRESSION 1 (TOC1); CONTAINS InterPro DOMAIN/s: CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789), CCT domain (InterPro:IPR010402); BEST Arabidopsis thaliana protein match is: pseudo-response regulator 3 (TAIR:AT5G60100.3); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (q689g9|prr1_orysa : 176.0) Two-component response regulator-like PRR1 (Pseudo-response regulator 1) (OsPRR1) - Oryza sativa (Rice) & (reliability: 396.0) & (original description: no original description) kfl00059_0230_v1.1 0.887854677322633 74 Kfl00425_0030 (at3g18370 : 142.0) ATSYTF; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT5G11100.1); Has 5534 Blast hits to 4008 proteins in 246 species: Archae - 0; Bacteria - 0; Metazoa - 3360; Fungi - 437; Plants - 1305; Viruses - 0; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 284.0) & (original description: no original description) kfl00425_0030_v1.1 0.8866072079426509 75 Kfl00224_0030 no hits & (original description: no original description) kfl00224_0030_v1.1 0.8863445986011783 76 Kfl00063_0180 (at1g65470 : 90.9) Chromatin Assembly Factor-1 (CAF-1) p150 subunit. Mutants have reduced heterochromatin content. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis.; FASCIATA 1 (FAS1); FUNCTIONS IN: histone binding; INVOLVED IN: in 11 processes; LOCATED IN: chromatin assembly complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Chromatin assembly factor 1 subunit A (InterPro:IPR022043). & (reliability: 181.8) & (original description: no original description) kfl00063_0180_v1.1 0.8861795451267515 77 Kfl00169_0080 no hits & (original description: no original description) kfl00169_0080_v1.1 0.8855211918719597 78 Kfl00198_0060 (at1g72050 : 83.2) Encodes a transcriptional factor TFIIIA required for transcription of 5S rRNA gene. 5S rRNA is the smallest constituent of the ribosome. Work on one of the gene models AT1G72050.2 showed that it encodes a protein with nine Cys(2)-His(2)-type zinc fingers, a characteristic feature of TFIIIA proteins. AT1G72050.2 also contains a 23 amino acid spacer between fingers 1 and 2, a 66 amino acid spacer between fingers 4 and 5, and a 50 amino acid non-finger C-terminal tail. in vitro assay demonstrated that AT1g72050.2 binds to 5S rDNA and efficiently stimulates the transcription of 5S rRNA. AT1g72050.2 also binds to 5S rRNA in vitro. AT1g72050.2 is located at several nuclear foci including the nucleolus and is absent from the cytoplasm.; transcription factor IIIA (TFIIIA); FUNCTIONS IN: 5S rRNA binding, zinc ion binding, sequence-specific DNA binding transcription factor activity, 5S rDNA binding, nucleic acid binding; INVOLVED IN: biological_process unknown; LOCATED IN: nucleolus, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, C2H2-like (InterPro:IPR015880), Zinc finger, C2H2-type (InterPro:IPR007087), Zinc finger, C2H2-type/integrase, DNA-binding (InterPro:IPR013087); BEST Arabidopsis thaliana protein match is: relative of early flowering 6 (TAIR:AT3G48430.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 166.4) & (original description: no original description) kfl00198_0060_v1.1 0.8852243921393547 79 Kfl00001_0690 (at5g62410 : 1028.0) SMC2-1 (SMC2); structural maintenance of chromosomes 2 (SMC2); FUNCTIONS IN: transporter activity; INVOLVED IN: chromosome organization; LOCATED IN: condensin complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: Structural maintenance of chromosomes (SMC) family protein (TAIR:AT3G47460.1); Has 126046 Blast hits to 65003 proteins in 3391 species: Archae - 1784; Bacteria - 23628; Metazoa - 52968; Fungi - 10094; Plants - 6737; Viruses - 431; Other Eukaryotes - 30404 (source: NCBI BLink). & (reliability: 2056.0) & (original description: no original description) kfl00001_0690_v1.1 0.8849966769435017 96 Kfl00733_0030 no hits & (original description: no original description) kfl00733_0030_v1.1 0.8848370475112213 81 Kfl00539_0100 no hits & (original description: no original description) kfl00539_0100_v1.1 0.8848256184683201 82 Kfl00561_0040 no hits & (original description: no original description) kfl00561_0040_v1.1 0.8848059805902897 83 Kfl00336_0090 no hits & (original description: no original description) kfl00336_0090_v1.1 0.8847457253431512 84 Kfl00128_0250 (at5g43080 : 138.0) Cyclin A3;1 (CYCA3;1); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin (InterPro:IPR006670), G2/mitotic-specific cyclin A (InterPro:IPR015453), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin, A/B/D/E (InterPro:IPR014400); BEST Arabidopsis thaliana protein match is: cyclin-dependent protein kinase 3;2 (TAIR:AT1G47210.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (p25010|ccnal_dauca : 132.0) G2/mitotic-specific cyclin C13-1 (A-like cyclin) (Fragment) - Daucus carota (Carrot) & (reliability: 276.0) & (original description: no original description) kfl00128_0250_v1.1 0.884433987115608 85 Kfl00494_0040 (at3g57180 : 320.0) BRASSINAZOLE(BRZ) INSENSITIVE PALE GREEN 2 (BPG2); FUNCTIONS IN: GTP binding; INVOLVED IN: brassinosteroid mediated signaling pathway, developmental process; LOCATED IN: chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: GTP-binding protein, HSR1-related (InterPro:IPR002917); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT4G10620.1); Has 5185 Blast hits to 4152 proteins in 947 species: Archae - 97; Bacteria - 1334; Metazoa - 1316; Fungi - 649; Plants - 254; Viruses - 94; Other Eukaryotes - 1441 (source: NCBI BLink). & (q6ypg5|nos_orysa : 84.0) Putative nitric-oxide synthase (EC 1.14.13.39) - Oryza sativa (Rice) & (reliability: 640.0) & (original description: no original description) kfl00494_0040_v1.1 0.8841590076253464 86 Kfl00326_0090 (q5z987|atr_orysa : 1092.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (at5g40820 : 1011.0) Encodes a Arabidopsis ortholog of the ATR protein kinase that is involved in a wide range of responses to DNA damage and plays a central role in cell-cycle regulation. Dominant loss of function alleles identified as suppressors of ALS also exhibit increased tolerance to aluminum. This may be due to the inhibition of terminal differentiation of the root apex upon exposure to Al.; Ataxia telangiectasia-mutated and RAD3-related (ATR); FUNCTIONS IN: protein serine/threonine kinase activity, inositol or phosphatidylinositol kinase activity, binding, phosphotransferase activity, alcohol group as acceptor; INVOLVED IN: in 9 processes; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), UME (InterPro:IPR012993), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase (InterPro:IPR014009), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: ataxia-telangiectasia mutated (TAIR:AT3G48190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 2022.0) & (original description: no original description) kfl00326_0090_v1.1 0.8834687126419959 87 Kfl00004_0070 (at3g19180 : 127.0) Encodes a chloroplast division factor located in the plastid inner envelope with its N-terminus exposed to the stroma. PARC6 influences FtsZ assembly and is required for recruitment of PDV1 during chloroplast division.; paralog of ARC6 (PARC6); BEST Arabidopsis thaliana protein match is: Chaperone DnaJ-domain superfamily protein (TAIR:AT5G42480.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 254.0) & (original description: no original description) kfl00004_0070_v1.1 0.8831519121201559 88 Kfl00279_0130 (at4g30870 : 152.0) Encodes an Arabidopsis homolog of the endonuclease MSU81. T-DNA insertion lines of AtMSU81 have a deficiency in homologous recombination in somatic cells but only after genotoxic stress. Crosses with a hyperrecombinogenic mutant of the AtRecQ4A helicase resulted in synthetic lethality in the double mutant.; MMS AND UV SENSITIVE 81 (MUS81); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166), Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), Restriction endonuclease, type II-like (InterPro:IPR011335); BEST Arabidopsis thaliana protein match is: Restriction endonuclease, type II-like superfamily protein (TAIR:AT5G39770.1); Has 631 Blast hits to 481 proteins in 192 species: Archae - 11; Bacteria - 4; Metazoa - 158; Fungi - 249; Plants - 48; Viruses - 0; Other Eukaryotes - 161 (source: NCBI BLink). & (reliability: 304.0) & (original description: no original description) kfl00279_0130_v1.1 0.8828602891592428 89 Kfl00031_0500 (at5g41790 : 99.4) encodes a protein that physically interacts specifically with the putative coiled-coil region of COP1 in vitro. In hypocotyl and cotyledon protoplasts, it is associated to the cytoskeleton, but not in the root. expression is not regulated by light.; COP1-interactive protein 1 (CIP1); FUNCTIONS IN: protein binding; INVOLVED IN: regulation of protein import into nucleus; LOCATED IN: cytoskeleton, plasma membrane, chloroplast, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin (InterPro:IPR009053); BEST Arabidopsis thaliana protein match is: myosin heavy chain-related (TAIR:AT1G64330.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 198.8) & (original description: no original description) kfl00031_0500_v1.1, kfl00031_0500_v1.1 0.882071665709914 90 Kfl00662_0040 (at1g16520 : 201.0) unknown protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G56080.1); Has 243 Blast hits to 234 proteins in 69 species: Archae - 2; Bacteria - 2; Metazoa - 61; Fungi - 9; Plants - 125; Viruses - 0; Other Eukaryotes - 44 (source: NCBI BLink). & (reliability: 402.0) & (original description: no original description) kfl00662_0040_v1.1 0.8819671343853884 91 Kfl00117_0160 no hits & (original description: no original description) kfl00117_0160_v1.1 0.8816959141936368 92 Kfl00264_0240 no hits & (original description: no original description) kfl00264_0240_v1.1 0.8805589481127493 99 Kfl00165_0140 (at4g29910 : 184.0) Origin Recognition Complex subunit 5. Involved in the initiation of DNA replication. Interacts strongly with all ORC subunits.; origin recognition complex protein 5 (ORC5); CONTAINS InterPro DOMAIN/s: Origin recognition complex, subunit 5 (InterPro:IPR020796); Has 287 Blast hits to 283 proteins in 127 species: Archae - 0; Bacteria - 0; Metazoa - 140; Fungi - 92; Plants - 43; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink). & (reliability: 368.0) & (original description: no original description) kfl00165_0140_v1.1 0.8802441165248834 94 Kfl00768_0030 (at4g17610 : 561.0) tRNA/rRNA methyltransferase (SpoU) family protein; FUNCTIONS IN: RNA binding, RNA methyltransferase activity; INVOLVED IN: RNA processing; LOCATED IN: endomembrane system; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: tRNA/rRNA methyltransferase, SpoU (InterPro:IPR001537); Has 6630 Blast hits to 6614 proteins in 1865 species: Archae - 7; Bacteria - 4787; Metazoa - 103; Fungi - 50; Plants - 109; Viruses - 0; Other Eukaryotes - 1574 (source: NCBI BLink). & (reliability: 1122.0) & (original description: no original description) kfl00768_0030_v1.1 0.8801433560813577 95 Kfl00110_0210 no hits & (original description: no original description) kfl00110_0210_v1.1 0.879927668795947 96 Kfl00130_0130 (at5g27740 : 530.0) A locus involved in embryogenesis. Mutations in this locus result in embryo lethality.; EMBRYO DEFECTIVE 2775 (EMB2775); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp-loader complex, subunit E, C-terminal (InterPro:IPR019483), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921); BEST Arabidopsis thaliana protein match is: ATPase family associated with various cellular activities (AAA) (TAIR:AT1G21690.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1060.0) & (original description: no original description) kfl00130_0130_v1.1 0.8798715888116448 97 Kfl00212_0060 (at4g23940 : 379.0) FtsH extracellular protease family; FUNCTIONS IN: in 6 functions; INVOLVED IN: proteolysis; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), Peptidase M41 (InterPro:IPR000642); BEST Arabidopsis thaliana protein match is: FtsH extracellular protease family (TAIR:AT2G30950.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q9bae0|ftsh_medsa : 278.0) Cell division protease ftsH homolog, chloroplast precursor (EC 3.4.24.-) - Medicago sativa (Alfalfa) & (reliability: 758.0) & (original description: no original description) kfl00212_0060_v1.1 0.879798142821828 98 Kfl00266_0120 (at3g24495 : 377.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH7 exhibit moderate affinity for a (T/G) substrate and weak binding of (+T), suggesting MSH2*MSH7 may be specialized for lesions/base mispairs not tested or for (T/G) mispairs in special contexts.; MUTS homolog 7 (MSH7); FUNCTIONS IN: damaged DNA binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 17871 Blast hits to 13835 proteins in 2667 species: Archae - 197; Bacteria - 11731; Metazoa - 1028; Fungi - 1274; Plants - 566; Viruses - 3; Other Eukaryotes - 3072 (source: NCBI BLink). & (q9xgc9|msh2_maize : 157.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 754.0) & (original description: no original description) kfl00266_0120_v1.1 0.8789631511239053 100