Sequence Description Alias PCC hrr Kfl00608_0090 (at5g61460 : 571.0) Encodes SMC6B (STRUCTURAL MAINTENANCE OF CHROMOSOMES 6B), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.; hypersensitive to MMS, irradiation and MMC (MIM); FUNCTIONS IN: ATP binding; INVOLVED IN: double-strand break repair, sister chromatid cohesion, chromosome segregation, response to X-ray, double-strand break repair via homologous recombination; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 6A (TAIR:AT5G07660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1142.0) & (original description: no original description) kfl00608_0090_v1.1 0.9696182256628356 4 Kfl00759_0050 no hits & (original description: no original description) kfl00759_0050_v1.1 0.9632772557358426 2 Kfl00031_0310 (at2g05210 : 102.0) Encodes AtPOT1a, an accessory factor for telomerase required for positive telomere length regulation. Note on nomenclature: different names have been given to Arabidopsis POT-like genes (Kuchar and Fajkus, 2004; Shakirov et al, 2005; Tani and Murata, 2005). According to a unifying nomenclature (Surovtseva et al, 2007), At2g05210 (previously named AtPOT1) is designated AtPOT1a, while At5g06310 (previously named AtPOT2) is designated AtPOT1b.; Protection of Telomeres 1a (AtPOT1a); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Telomere end binding protein (InterPro:IPR011564); BEST Arabidopsis thaliana protein match is: Nucleic acid-binding, OB-fold-like protein (TAIR:AT5G06310.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 204.0) & (original description: no original description) kfl00031_0310_v1.1 0.9584855772251561 12 Kfl00144_0030 (at1g18335 : 168.0) Acyl-CoA N-acyltransferases (NAT) superfamily protein; FUNCTIONS IN: N-acetyltransferase activity; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Acyl-CoA N-acyltransferase (InterPro:IPR016181); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 336.0) & (original description: no original description) kfl00144_0030_v1.1 0.957096443887703 4 Kfl00153_0160 (at4g02070 : 834.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.; MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). & (q9xgc9|msh2_maize : 175.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 1668.0) & (original description: no original description) kfl00153_0160_v1.1 0.9543536965250363 5 Kfl00181_0220 (at4g08990 : 1038.0) DNA (cytosine-5-)-methyltransferase family protein; FUNCTIONS IN: DNA binding, DNA (cytosine-5-)-methyltransferase activity; INVOLVED IN: DNA methylation; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: DNA (cytosine-5)-methyltransferase 1 (InterPro:IPR017198), DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), DNA methylase, C-5 cytosine-specific, active site (InterPro:IPR018117); BEST Arabidopsis thaliana protein match is: DNA methyltransferase 2 (TAIR:AT4G14140.1); Has 7214 Blast hits to 6137 proteins in 1440 species: Archae - 249; Bacteria - 4362; Metazoa - 525; Fungi - 274; Plants - 335; Viruses - 111; Other Eukaryotes - 1358 (source: NCBI BLink). & (q9axt8|cmt1_maize : 184.0) DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Chromomethylase 1) (Zea methyltransferase2) (Zmet2) (DNA cytosine methyltransferase MET2a) - Zea mays (Maize) & (reliability: 2076.0) & (original description: no original description) kfl00181_0220_v1.1 0.9491544988990074 26 Kfl00302_0040 no hits & (original description: no original description) kfl00302_0040_v1.1 0.9486890562020827 20 Kfl00072_0060 (at1g57820 : 631.0) Encodes a 645-amino acid methylcytosine-binding protein with a PHD domain, two RING finger domains, and an SRA domain that is involved in centromere heterochromatinization. This protein functions as an E3 ubiquitin ligase in vitro. The protein has been shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the former. It plays a role in the establishment/maintenance of chromatin structure during cell division and is localized in the nucleus. Plants over-expressing VIM1/ORTH2 show an inhibition in root growth and a delay in flowering. Both over-expression of GFP:ORTH2 and loss of ORTH2/VIM1 lead to decreased levels of DNA methylation. GFP:ORTH2 over-expressers also have increased levels of FWA transcripts.; VARIANT IN METHYLATION 1 (VIM1); CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), SRA-YDG (InterPro:IPR003105), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57800.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1262.0) & (original description: no original description) kfl00072_0060_v1.1, kfl00072_0060_v1.1 0.9423450496838373 34 Kfl00007_0070 (at1g59600 : 87.0) ZCW7; Has 136 Blast hits to 136 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 101; Fungi - 0; Plants - 35; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). & (reliability: 174.0) & (original description: no original description) kfl00007_0070_v1.1 0.9354760653407292 9 Kfl00055_0170 (at3g57060 : 412.0) binding; FUNCTIONS IN: binding; INVOLVED IN: mitosis, chromosome condensation; LOCATED IN: nucleus, condensin complex; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Non-SMC condensin subunit, XCAP-D2/Cnd1 (InterPro:IPR007673), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: binding (TAIR:AT4G15890.1). & (reliability: 824.0) & (original description: no original description) kfl00055_0170_v1.1 0.9340290592673266 32 Kfl00001_0690 (at5g62410 : 1028.0) SMC2-1 (SMC2); structural maintenance of chromosomes 2 (SMC2); FUNCTIONS IN: transporter activity; INVOLVED IN: chromosome organization; LOCATED IN: condensin complex; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: Structural maintenance of chromosomes (SMC) family protein (TAIR:AT3G47460.1); Has 126046 Blast hits to 65003 proteins in 3391 species: Archae - 1784; Bacteria - 23628; Metazoa - 52968; Fungi - 10094; Plants - 6737; Viruses - 431; Other Eukaryotes - 30404 (source: NCBI BLink). & (reliability: 2056.0) & (original description: no original description) kfl00001_0690_v1.1 0.9332413009030441 34 Kfl00125_0020 (at2g13370 : 403.0) chromatin remodeling 5 (CHR5); FUNCTIONS IN: chromatin binding, helicase activity, DNA binding, nucleic acid binding, ATP binding; INVOLVED IN: chromatin assembly or disassembly; LOCATED IN: chromatin, nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Chromo domain (InterPro:IPR000953), SNF2-related (InterPro:IPR000330), Homeodomain-like (InterPro:IPR009057), DEAD-like helicase, N-terminal (InterPro:IPR014001), Chromo domain-like (InterPro:IPR016197), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: chromatin remodeling factor CHD3 (PICKLE) (TAIR:AT2G25170.1); Has 38529 Blast hits to 28045 proteins in 2467 species: Archae - 189; Bacteria - 9973; Metazoa - 8887; Fungi - 6205; Plants - 2508; Viruses - 447; Other Eukaryotes - 10320 (source: NCBI BLink). & (q7g8y3|isw2_orysa : 384.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 776.0) & (original description: no original description) kfl00125_0020_v1.1, kfl00125_0020_v1.1, kfl00125_0020_v1.1 0.9332043448989039 12 Kfl00418_0100 no hits & (original description: no original description) kfl00418_0100_v1.1 0.9330692596322515 33 Kfl00349_0050 (o48653|dpola_orysa : 1124.0) DNA polymerase alpha catalytic subunit (EC 2.7.7.7) - Oryza sativa (Rice) & (at5g67100 : 1019.0) Encodes the putative catalytic subunit of the DNA polymerase alpha. Interacts with genes involved in chromatin-mediated cellular memory. ICU2 genetically interacts with TERMINAL FLOWER2, the ortholog of HETEROCHROMATIN PROTEIN1 of animals and yeasts, and with the Polycomb group (PcG) gene CURLY LEAF. A number of regulatory genes were derepressed in the icu2-1 mutant, including genes associated with flowering time, floral meristem, and floral organ identity. Mutant has curled, involute leaves and causes early flowering.; INCURVATA2 (ICU2); FUNCTIONS IN: DNA-directed DNA polymerase activity; INVOLVED IN: negative regulation of flower development, leaf morphogenesis; LOCATED IN: nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134), Zinc finger, DNA-directed DNA polymerase, family B, alpha (InterPro:IPR015088), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved site (InterPro:IPR017964), DNA-directed DNA polymerase, family B (InterPro:IPR006172), DNA-directed DNA polymerase, family B, pol2 (InterPro:IPR004578); BEST Arabidopsis thaliana protein match is: DNA binding;nucleotide binding;nucleic acid binding;DNA-directed DNA polymerases;DNA-directed DNA polymerases (TAIR:AT5G63960.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 2038.0) & (original description: no original description) kfl00349_0050_v1.1 0.9311491472980913 45 Kfl00281_0130 no hits & (original description: no original description) kfl00281_0130_v1.1 0.9309915823959092 15 Kfl00100_0250 (at1g67320 : 534.0) DNA primase, large subunit family; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, large subunit, eukaryotic (InterPro:IPR016558), DNA primase, large subunit, eukaryotic/archaeal (InterPro:IPR007238). & (reliability: 1068.0) & (original description: no original description) kfl00100_0250_v1.1 0.9298145733025646 53 Kfl00063_0180 (at1g65470 : 90.9) Chromatin Assembly Factor-1 (CAF-1) p150 subunit. Mutants have reduced heterochromatin content. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis.; FASCIATA 1 (FAS1); FUNCTIONS IN: histone binding; INVOLVED IN: in 11 processes; LOCATED IN: chromatin assembly complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Chromatin assembly factor 1 subunit A (InterPro:IPR022043). & (reliability: 181.8) & (original description: no original description) kfl00063_0180_v1.1 0.929249575136636 19 Kfl00069_0130 (at5g22010 : 421.0) replication factor C1 (RFC1); FUNCTIONS IN: DNA clamp loader activity, nucleoside-triphosphatase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: DNA replication; LOCATED IN: DNA replication factor C complex, intracellular; CONTAINS InterPro DOMAIN/s: DNA replication factor RFC1, C-terminal (InterPro:IPR013725), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), DNA replication factor C, large subunit (InterPro:IPR012178), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT1G04730.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 842.0) & (original description: no original description) kfl00069_0130_v1.1 0.9291440474595378 18 Kfl00108_0130 (q8lpu5|cmt3_maize : 469.0) DNA (cytosine-5)-methyltransferase 3 (EC 2.1.1.37) (Chromomethylase 3) (DNA methyltransferase 105) - Zea mays (Maize) & (at4g19020 : 419.0) chromomethylase 2 (CMT2); FUNCTIONS IN: chromatin binding, DNA binding; INVOLVED IN: chromatin assembly or disassembly, DNA methylation; LOCATED IN: chromatin, nucleus; CONTAINS InterPro DOMAIN/s: DNA methylase, C-5 cytosine-specific (InterPro:IPR001525), Chromo domain-like (InterPro:IPR016197), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), Chromo domain (InterPro:IPR000953); BEST Arabidopsis thaliana protein match is: chromomethylase 3 (TAIR:AT1G69770.1); Has 5135 Blast hits to 4403 proteins in 1000 species: Archae - 207; Bacteria - 2602; Metazoa - 790; Fungi - 215; Plants - 463; Viruses - 25; Other Eukaryotes - 833 (source: NCBI BLink). & (reliability: 838.0) & (original description: no original description) kfl00108_0130_v1.1 0.927041048647937 54 Kfl00007_0060 (at5g01630 : 307.0) Ortholog of breast cancer susceptibility protein 2. Essential at meiosis. Interacts with with both Rad51 and Dss1(I) or both Dmc1 and Dss1(I) in a tripartite complex.; BRCA2-like B (BRCA2B); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis; LOCATED IN: mitochondrion; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BREAST CANCER 2 like 2A (TAIR:AT4G00020.1); Has 281 Blast hits to 210 proteins in 91 species: Archae - 0; Bacteria - 4; Metazoa - 134; Fungi - 18; Plants - 61; Viruses - 0; Other Eukaryotes - 64 (source: NCBI BLink). & (reliability: 614.0) & (original description: no original description) kfl00007_0060_v1.1 0.9268672823894318 30 Kfl00039_0170 (at2g32590 : 335.0) LOCATED IN: chloroplast; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Barren (InterPro:IPR008418); Has 467 Blast hits to 447 proteins in 202 species: Archae - 0; Bacteria - 4; Metazoa - 147; Fungi - 168; Plants - 39; Viruses - 1; Other Eukaryotes - 108 (source: NCBI BLink). & (reliability: 670.0) & (original description: no original description) kfl00039_0170_v1.1 0.92527841272639 50 Kfl00108_0080 no hits & (original description: no original description) kfl00108_0080_v1.1 0.9250035356788112 44 Kfl00208_0200 (at3g48540 : 256.0) Cytidine/deoxycytidylate deaminase family protein; FUNCTIONS IN: hydrolase activity, zinc ion binding, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: APOBEC/CMP deaminase, zinc-binding (InterPro:IPR016192), CMP/dCMP deaminase, zinc-binding (InterPro:IPR002125), Cytidine deaminase-like (InterPro:IPR016193), Cytidine deaminase (InterPro:IPR015517); Has 3737 Blast hits to 3733 proteins in 1421 species: Archae - 65; Bacteria - 2323; Metazoa - 218; Fungi - 134; Plants - 52; Viruses - 89; Other Eukaryotes - 856 (source: NCBI BLink). & (reliability: 512.0) & (original description: no original description) kfl00208_0200_v1.1 0.9241699444402491 23 Kfl00156_0260 no hits & (original description: no original description) kfl00156_0260_v1.1 0.9228393619577152 24 Kfl00411_0100 (at5g48600 : 1014.0) member of SMC subfamily; structural maintenance of chromosome 3 (SMC3); FUNCTIONS IN: transporter activity, ATP binding; INVOLVED IN: chromosome segregation, chromosome organization; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 2 (TAIR:AT5G62410.1). & (reliability: 2028.0) & (original description: no original description) kfl00411_0100_v1.1 0.9221506028278701 46 Kfl00050_0180 (at1g27880 : 512.0) DEAD/DEAH box RNA helicase family protein ; FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: DNA recombination; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEAD/DEAH box RNA helicase family protein (TAIR:AT4G35740.1); Has 41244 Blast hits to 39032 proteins in 2984 species: Archae - 762; Bacteria - 21282; Metazoa - 5401; Fungi - 4173; Plants - 3671; Viruses - 588; Other Eukaryotes - 5367 (source: NCBI BLink). & (reliability: 1024.0) & (original description: no original description) kfl00050_0180_v1.1 0.9193433440828741 26 Kfl00489_0040 (at2g21790 : 1267.0) encodes large subunit of ribonucleotide reductase involved in the production of deoxyribonucleoside triphosphates (dNTPs) for DNA replication and repair; ribonucleotide reductase 1 (RNR1); FUNCTIONS IN: ribonucleoside-diphosphate reductase activity, ATP binding; INVOLVED IN: response to cadmium ion, DNA replication, deoxyribonucleoside triphosphate biosynthetic process; LOCATED IN: ribonucleoside-diphosphate reductase complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribonucleotide reductase large subunit, N-terminal (InterPro:IPR013509), Ribonucleoside-diphosphate reductase, alpha subunit (InterPro:IPR013346), ATP-cone (InterPro:IPR005144), Ribonucleotide reductase large subunit, C-terminal (InterPro:IPR000788), Ribonucleotide reductase R1 subunit, N-terminal (InterPro:IPR008926); Has 15326 Blast hits to 14804 proteins in 2790 species: Archae - 206; Bacteria - 6388; Metazoa - 177; Fungi - 215; Plants - 88; Viruses - 606; Other Eukaryotes - 7646 (source: NCBI BLink). & (reliability: 2534.0) & (original description: no original description) kfl00489_0040_v1.1 0.9189461338212586 56 Kfl00244_0090 (p55857|smt3_orysa : 150.0) Ubiquitin-like protein SMT3 - Oryza sativa (Rice) & (at4g26840 : 149.0) Encodes a small ubiquitin-like modifier (SUMO) polypeptide that becomes covalently attached to various intracellular protein targets, much like ubiquitination, leading to post-translational modification of those targets.; small ubiquitin-like modifier 1 (SUMO1); CONTAINS InterPro DOMAIN/s: Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: small ubiquitin-like modifier 2 (TAIR:AT5G55160.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 298.0) & (original description: no original description) kfl00244_0090_v1.1 0.9172049375275358 28 Kfl00116_0090 (at1g04020 : 184.0) Encodes a protein containing two tandem BRCA1 C-Terminal (BRCT) domains, which function in phosphorylation-dependent proteinñprotein interactions.Loss of function mutations cause defects in meristem organization due to failure to repress WUS. BARD1 binds to WUS promoter and over expression of BARD reduces the extent of WUS expression.; breast cancer associated RING 1 (BARD1); FUNCTIONS IN: transcription coactivator activity, DNA binding; INVOLVED IN: DNA repair, regulation of meristem structural organization, leaf development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer susceptibility1 (TAIR:AT4G21070.1); Has 6045 Blast hits to 5706 proteins in 320 species: Archae - 0; Bacteria - 47; Metazoa - 4577; Fungi - 362; Plants - 542; Viruses - 11; Other Eukaryotes - 506 (source: NCBI BLink). & (reliability: 354.0) & (original description: no original description) kfl00116_0090_v1.1, kfl00116_0090_v1.1 0.916990206955259 53 Kfl00626_0050 (at3g18524 : 1095.0) Encodes a DNA mismatch repair homolog of human MutS gene, MSH6. MSH2 is involved in maintaining genome stability and repressing recombination of mismatched heteroduplexes.There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2 has different binding specificity to different mismatches in combination with MSH3, MSH6, or MSH7.; MUTS homolog 2 (MSH2); FUNCTIONS IN: damaged DNA binding, protein binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, negative regulation of reciprocal meiotic recombination; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein, MSH2 (InterPro:IPR011184); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1); Has 13560 Blast hits to 13453 proteins in 2654 species: Archae - 128; Bacteria - 8942; Metazoa - 734; Fungi - 813; Plants - 457; Viruses - 3; Other Eukaryotes - 2483 (source: NCBI BLink). & (q9xgc9|msh2_maize : 1091.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 2190.0) & (original description: no original description) kfl00626_0050_v1.1 0.9156499269504123 30 Kfl00135_0100 (at5g41880 : 457.0) POLA3; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer, DNA replication; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, small subunit (InterPro:IPR002755), DNA primase, small subunit, eukaryotic/archaeal (InterPro:IPR014052); Has 510 Blast hits to 504 proteins in 249 species: Archae - 95; Bacteria - 0; Metazoa - 124; Fungi - 138; Plants - 44; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink). & (reliability: 914.0) & (original description: no original description) kfl00135_0100_v1.1 0.9149424593695109 42 Kfl00327_0060 (at4g32700 : 819.0) Encodes a homolog of Drosophila MUS308 and mammalian DNA polymerase, which prevent spontaneous or DNA damage-induced production of DNA double strand breaks. Two conserved functional domains: an N-terminal superfamily II DNA/RNA helicase domain and a C-terminal prokaryotic-type DNA polymerase I domain. Required for regulated cell division and differentiation in meristems. Mutant plants show morphological defects, such as short roots, serrated leaves, and fasciation, as well as defective patterns of cell division and differentiation in the meristem. Mutant plants had 2.5 to 4.5-fold higher expression of ATGR1, ATBRCA1 and RAD51 genes. TEB is required for normal progression of DNA replication and for correct expression of genes during development.; helicases;ATP-dependent helicases;nucleic acid binding;ATP binding;DNA-directed DNA polymerases;DNA binding; FUNCTIONS IN: in 6 functions; INVOLVED IN: regulation of gene expression, DNA replication, DNA recombination, photomorphogenesis; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA-directed DNA polymerase, family A, palm domain (InterPro:IPR001098), DNA/RNA helicase, C-terminal (InterPro:IPR001650), DNA polymerase A domain (InterPro:IPR002298), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: U5 small nuclear ribonucleoprotein helicase (TAIR:AT2G42270.1); Has 17628 Blast hits to 16579 proteins in 2941 species: Archae - 600; Bacteria - 7507; Metazoa - 1254; Fungi - 1190; Plants - 590; Viruses - 412; Other Eukaryotes - 6075 (source: NCBI BLink). & (reliability: 1638.0) & (original description: no original description) kfl00327_0060_v1.1 0.9146195857654079 32 Kfl00220_0150 no hits & (original description: no original description) kfl00220_0150_v1.1 0.9135242215109316 33 Kfl00062_0110 (at4g01160 : 99.8) BTB/POZ/Kelch-associated protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/Kelch-associated (InterPro:IPR011705), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: POZ/BTB containin G-protein 1 (TAIR:AT3G61600.2); Has 3481 Blast hits to 3463 proteins in 124 species: Archae - 0; Bacteria - 0; Metazoa - 3173; Fungi - 4; Plants - 136; Viruses - 49; Other Eukaryotes - 119 (source: NCBI BLink). & (reliability: 199.6) & (original description: no original description) kfl00062_0110_v1.1 0.9126467673132561 46 Kfl00094_0200 (at5g52910 : 319.0) homolog of Drosophila timeless; TIMELESS (ATIM); CONTAINS InterPro DOMAIN/s: Timeless C-terminal (InterPro:IPR007725), Timeless protein (InterPro:IPR006906); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 638.0) & (original description: no original description) kfl00094_0200_v1.1 0.9115423845726845 46 Kfl00209_0100 no hits & (original description: no original description) kfl00209_0100_v1.1 0.911025535375092 64 Kfl00057_0090 (at2g22140 : 132.0) Forms a complex with MUS81 that functions as endonuclease in DNA recombination and repair processes.; essential meiotic endonuclease 1B (EME1B); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166); BEST Arabidopsis thaliana protein match is: essential meiotic endonuclease 1A (TAIR:AT2G21800.1); Has 542 Blast hits to 486 proteins in 142 species: Archae - 0; Bacteria - 42; Metazoa - 170; Fungi - 104; Plants - 48; Viruses - 0; Other Eukaryotes - 178 (source: NCBI BLink). & (reliability: 264.0) & (original description: no original description) kfl00057_0090_v1.1 0.9109330588323138 37 Kfl00561_0040 no hits & (original description: no original description) kfl00561_0040_v1.1 0.9103986014949942 43 Kfl00110_0030 (at3g27640 : 283.0) Transducin/WD40 repeat-like superfamily protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT2G43770.1); Has 36714 Blast hits to 22017 proteins in 645 species: Archae - 42; Bacteria - 5151; Metazoa - 14249; Fungi - 8186; Plants - 4562; Viruses - 0; Other Eukaryotes - 4524 (source: NCBI BLink). & (reliability: 566.0) & (original description: no original description) kfl00110_0030_v1.1 0.9094928716333456 57 Kfl00381_0040 (at1g10930 : 306.0) DNA helicase involved in the maintenance of genome stability by modulation of the DNA damage response and suppression of homologous recombination.; RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink). & (reliability: 612.0) & (original description: no original description) kfl00381_0040_v1.1, kfl00381_0040_v1.1 0.9083714905472238 59 Kfl00222_0100 (at5g37630 : 265.0) EMBRYO DEFECTIVE 2656 (EMB2656); FUNCTIONS IN: binding; INVOLVED IN: mitotic chromosome condensation, embryo development ending in seed dormancy; LOCATED IN: cellular_component unknown; EXPRESSED IN: 11 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-type fold (InterPro:IPR016024); Has 333 Blast hits to 316 proteins in 147 species: Archae - 0; Bacteria - 4; Metazoa - 113; Fungi - 138; Plants - 47; Viruses - 0; Other Eukaryotes - 31 (source: NCBI BLink). & (reliability: 530.0) & (original description: no original description) kfl00222_0100_v1.1 0.9080603992802734 56 Kfl00201_0050 no hits & (original description: no original description) kfl00201_0050_v1.1 0.9062731982251944 49 Kfl00360_0070 (at4g02110 : 142.0) transcription coactivators; FUNCTIONS IN: transcription coactivator activity; INVOLVED IN: biological_process unknown; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: zinc finger (C3HC4-type RING finger) family protein / BRCT domain-containing protein (TAIR:AT1G67180.1); Has 6090 Blast hits to 4661 proteins in 497 species: Archae - 12; Bacteria - 945; Metazoa - 2581; Fungi - 684; Plants - 424; Viruses - 13; Other Eukaryotes - 1431 (source: NCBI BLink). & (reliability: 284.0) & (original description: no original description) kfl00360_0070_v1.1 0.9057117871454071 43 Kfl00349_0100 (at3g60830 : 373.0) Encodes an actin-related protein required for normal embryogenesis, plant architecture and floral organ abscission.; actin-related protein 7 (ARP7); CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000); BEST Arabidopsis thaliana protein match is: actin 3 (TAIR:AT3G53750.1); Has 12219 Blast hits to 11995 proteins in 2504 species: Archae - 0; Bacteria - 50; Metazoa - 5224; Fungi - 3189; Plants - 1407; Viruses - 2; Other Eukaryotes - 2347 (source: NCBI BLink). & (p30173|act13_soltu : 236.0) Actin-101 - Solanum tuberosum (Potato) & (reliability: 746.0) & (original description: no original description) kfl00349_0100_v1.1 0.9052970451327457 44 Kfl00147_0050 (at1g08600 : 369.0) ATRX; FUNCTIONS IN: helicase activity, DNA binding, ATP binding, nucleic acid binding; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: homolog of RAD54 (TAIR:AT3G19210.1). & (gnl|cdd|68872 : 195.0) no description available & (q7g8y3|isw2_orysa : 102.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (gnl|cdd|39774 : 94.4) no description available & (reliability: 738.0) & (original description: no original description) kfl00147_0050_v1.1 0.9052085272470278 45 Kfl00394_0110 (at2g20980 : 139.0) Similar to MCM10, which in other organism was shown to be involved in the initiation of DNA replication.; minichromosome maintenance 10 (MCM10); CONTAINS InterPro DOMAIN/s: Zinc finger, Mcm10/DnaG-type (InterPro:IPR015408); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 278.0) & (original description: no original description) kfl00394_0110_v1.1 0.9049240684156069 54 Kfl00200_0040 (at5g22750 : 253.0) DNA repair gene. gamma-radiation hypersensitive (RAD5) involved in stable transformation and T-DNA transfer; RAD5; FUNCTIONS IN: in 6 functions; INVOLVED IN: DNA mediated transformation; EXPRESSED IN: embryo, sperm cell, seed; EXPRESSED DURING: E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), HIP116, Rad5p N-terminal (InterPro:IPR014905), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: Helicase protein with RING/U-box domain (TAIR:AT5G43530.1); Has 27107 Blast hits to 18179 proteins in 1771 species: Archae - 108; Bacteria - 7266; Metazoa - 8140; Fungi - 5089; Plants - 2446; Viruses - 173; Other Eukaryotes - 3885 (source: NCBI BLink). & (reliability: 468.0) & (original description: no original description) kfl00200_0040_v1.1, kfl00200_0040_v1.1 0.9038893880105883 47 Kfl00066_0340 (at3g42660 : 451.0) transducin family protein / WD-40 repeat family protein; CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), WD40 repeat-like-containing domain (InterPro:IPR011046), Protein of unknown function DUF3639 (InterPro:IPR022100), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT5G23430.1); Has 41589 Blast hits to 20655 proteins in 706 species: Archae - 66; Bacteria - 8583; Metazoa - 14223; Fungi - 8894; Plants - 4578; Viruses - 3; Other Eukaryotes - 5242 (source: NCBI BLink). & (reliability: 902.0) & (original description: no original description) kfl00066_0340_v1.1 0.9035116538286488 62 Kfl00029_0090 no hits & (original description: no original description) kfl00029_0090_v1.1 0.9033224553421859 56 Kfl00323_0110 no hits & (original description: no original description) kfl00323_0110_v1.1 0.9019658512027762 50 Kfl00061_0280 (at1g08260 : 1660.0) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 3320.0) & (original description: no original description) kfl00061_0280_v1.1 0.9017072678514942 65 Kfl00545_0070 (at3g02920 : 139.0) RPA32B; FUNCTIONS IN: nucleic acid binding; INVOLVED IN: biological_process unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Replication protein A, subunit RPA32 (InterPro:IPR014646), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Replication protein A, C-terminal (InterPro:IPR014892); BEST Arabidopsis thaliana protein match is: replicon protein A2 (TAIR:AT2G24490.2). & (reliability: 278.0) & (original description: no original description) kfl00545_0070_v1.1 0.901115218094286 52 Kfl00014_0390 (at4g20325 : 186.0) FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Ribonuclease H2, subunit B (InterPro:IPR019024); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 372.0) & (original description: no original description) kfl00014_0390_v1.1 0.9005741224222857 63 Kfl00001_0700 no hits & (original description: no original description) kfl00001_0700_v1.1 0.8986875775007359 54 Kfl00028_0260 (at2g44580 : 266.0) zinc ion binding; CONTAINS InterPro DOMAIN/s: Sister chromatid cohesion protein DCC1 (InterPro:IPR019128); Has 214 Blast hits to 211 proteins in 110 species: Archae - 0; Bacteria - 0; Metazoa - 115; Fungi - 49; Plants - 36; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink). & (reliability: 532.0) & (original description: no original description) kfl00028_0260_v1.1 0.8986335752305015 62 Kfl00213_0030 (at1g04730 : 462.0) Necessary for sister chromatid cohesion. Acts in synergy with ETG1.; CHROMOSOME TRANSMISSION FIDELITY 18 (CTF18); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: sister chromatid cohesion; LOCATED IN: replication fork; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959); BEST Arabidopsis thaliana protein match is: replication factor C1 (TAIR:AT5G22010.1); Has 4018 Blast hits to 4006 proteins in 709 species: Archae - 400; Bacteria - 666; Metazoa - 673; Fungi - 766; Plants - 379; Viruses - 21; Other Eukaryotes - 1113 (source: NCBI BLink). & (reliability: 924.0) & (original description: no original description) kfl00213_0030_v1.1 0.8984114910175205 69 Kfl00005_0580 no hits & (original description: no original description) kfl00005_0580_v1.1 0.8978728886808515 72 Kfl00825_0020 no hits & (original description: no original description) kfl00825_0020_v1.1 0.8978120801865396 58 Kfl00025_0110 (at3g52155 : 141.0) Phosphoglycerate mutase family protein; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histidine phosphatase superfamily, clade-1 (InterPro:IPR013078); Has 1391 Blast hits to 1391 proteins in 390 species: Archae - 1; Bacteria - 792; Metazoa - 0; Fungi - 0; Plants - 44; Viruses - 0; Other Eukaryotes - 554 (source: NCBI BLink). & (reliability: 282.0) & (original description: no original description) kfl00025_0110_v1.1 0.8972897755307567 59 Kfl00004_0070 (at3g19180 : 127.0) Encodes a chloroplast division factor located in the plastid inner envelope with its N-terminus exposed to the stroma. PARC6 influences FtsZ assembly and is required for recruitment of PDV1 during chloroplast division.; paralog of ARC6 (PARC6); BEST Arabidopsis thaliana protein match is: Chaperone DnaJ-domain superfamily protein (TAIR:AT5G42480.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 254.0) & (original description: no original description) kfl00004_0070_v1.1 0.8968523641189529 60 Kfl00109_0210 (at5g64630 : 397.0) Chromatin Assembly Factor-1 (CAF-1) p60 subunit. Involved in organization of the shoot and root apical meristems. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis.; FASCIATA 2 (FAS2); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40 repeat, conserved site (InterPro:IPR019775), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat (InterPro:IPR001680), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: homolog of histone chaperone HIRA (TAIR:AT3G44530.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (p93107|pf20_chlre : 84.0) Flagellar WD repeat protein PF20 - Chlamydomonas reinhardtii & (reliability: 794.0) & (original description: no original description) kfl00109_0210_v1.1 0.8966337362099647 63 Kfl00614_0020 (at3g13870 : 803.0) required for regulated cell expansion and normal root hair development. Encodes an evolutionarily conserved protein with putative GTP-binding motifs that is implicated in the control of vesicle trafficking between the endoplasmic reticulum and the Golgi compartments.; ROOT HAIR DEFECTIVE 3 (RHD3); FUNCTIONS IN: GTP binding; INVOLVED IN: root epidermal cell differentiation, plant-type cell wall biogenesis, ER to Golgi vesicle-mediated transport, actin cytoskeleton organization, cell tip growth; LOCATED IN: endoplasmic reticulum, plasma membrane, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Root hair defective 3 GTP-binding (InterPro:IPR008803); BEST Arabidopsis thaliana protein match is: Root hair defective 3 GTP-binding protein (RHD3) (TAIR:AT1G72960.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1606.0) & (original description: no original description) kfl00614_0020_v1.1 0.8962448903496582 62 Kfl00577_0060 (at3g54670 : 1011.0) Encodes a member of the Arabidopsis cohesin complex that is essential for viability and sister chromatid alignment.; TITAN8 (TTN8); CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosome 3 (TAIR:AT5G48600.1). & (reliability: 2022.0) & (original description: no original description) kfl00577_0060_v1.1 0.8952897588340993 63 Kfl00026_0260 (q9xfh3|mad2_maize : 253.0) Mitotic spindle checkpoint protein MAD2 - Zea mays (Maize) & (at3g25980 : 249.0) Encodes MAD2 (MITOTIC ARREST-DEFICIENT 2). May have the spindle assembly checkpoint protein functions conserved from yeast to humans.; MITOTIC ARREST-DEFICIENT 2 (MAD2); CONTAINS InterPro DOMAIN/s: DNA-binding HORMA (InterPro:IPR003511). & (reliability: 498.0) & (original description: no original description) kfl00026_0260_v1.1 0.8951438457196385 64 Kfl00208_0210 no hits & (original description: no original description) kfl00208_0210_v1.1 0.8938197315535389 67 Kfl00644_0020 (at4g14770 : 146.0) TESMIN/TSO1-like CXC 2 (TCX2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Tesmin/TSO1-like, CXC (InterPro:IPR005172); BEST Arabidopsis thaliana protein match is: Tesmin/TSO1-like CXC domain-containing protein (TAIR:AT3G22780.1); Has 1250 Blast hits to 741 proteins in 97 species: Archae - 0; Bacteria - 6; Metazoa - 464; Fungi - 8; Plants - 353; Viruses - 0; Other Eukaryotes - 419 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description) kfl00644_0020_v1.1 0.8921052123253476 66 Kfl00523_0070 (at5g58230 : 676.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1352.0) & (original description: no original description) kfl00523_0070_v1.1 0.8920336611390677 67 Kfl00203_0160 (at1g10930 : 726.0) DNA helicase involved in the maintenance of genome stability by modulation of the DNA damage response and suppression of homologous recombination.; RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink). & (reliability: 1452.0) & (original description: no original description) kfl00203_0160_v1.1, kfl00203_0160_v1.1 0.8913008363886517 68 Kfl00031_0500 (at5g41790 : 99.4) encodes a protein that physically interacts specifically with the putative coiled-coil region of COP1 in vitro. In hypocotyl and cotyledon protoplasts, it is associated to the cytoskeleton, but not in the root. expression is not regulated by light.; COP1-interactive protein 1 (CIP1); FUNCTIONS IN: protein binding; INVOLVED IN: regulation of protein import into nucleus; LOCATED IN: cytoskeleton, plasma membrane, chloroplast, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin (InterPro:IPR009053); BEST Arabidopsis thaliana protein match is: myosin heavy chain-related (TAIR:AT1G64330.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 198.8) & (original description: no original description) kfl00031_0500_v1.1, kfl00031_0500_v1.1 0.8911215958451764 69 Kfl00176_0100 (at5g58140 : 89.4) Membrane-bound protein serine/threonine kinase that functions as blue light photoreceptor in redundancy with PHO1. Involved in stomatal opening, chloroplast movement and phototropism. Mediates blue light-induced growth enhancements. PHOT1 and PHOT2 mediate blue light-dependent activation of the plasma membrane H+-ATPase in guard cell protoplasts. PHOT2 possesses two LOV (LOV1 and LOV2, for light-oxygen-voltage-sensing) domains involved in FMN-binding and a C-terminus forming a serine/threonine kinase domain. LOV2 acts as an inhibitor of phototropin kinase in the dark, and light cancels the inhibition through cysteine-FMN adduct formation. LOV1 in contrast acts as an attenuator of photoactivation. Localized to the Golgi apparatus under the induction of blue light.; phototropin 2 (PHOT2); FUNCTIONS IN: protein serine/threonine kinase activity, FMN binding, kinase activity, blue light photoreceptor activity; INVOLVED IN: in 7 processes; LOCATED IN: Golgi apparatus, plasma membrane, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: PAC motif (InterPro:IPR001610), Protein kinase, ATP binding site (InterPro:IPR017441), PAS fold (InterPro:IPR013767), Serine/threonine-protein kinase domain (InterPro:IPR002290), PAS (InterPro:IPR000014), PAS-associated, C-terminal (InterPro:IPR000700), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Protein kinase, catalytic domain (InterPro:IPR000719); BEST Arabidopsis thaliana protein match is: phototropin 1 (TAIR:AT3G45780.2); Has 25181 Blast hits to 21357 proteins in 1460 species: Archae - 236; Bacteria - 6754; Metazoa - 8411; Fungi - 2718; Plants - 3113; Viruses - 9; Other Eukaryotes - 3940 (source: NCBI BLink). & (q5z8k3|ado1_orysa : 87.0) Adagio-like protein 1 - Oryza sativa (Rice) & (reliability: 169.4) & (original description: no original description) kfl00176_0100_v1.1, kfl00176_0100_v1.1, kfl00176_0100_v1.1 0.8906576032611594 70 Kfl00049_0150 no hits & (original description: no original description) kfl00049_0150_v1.1 0.8900737682083615 94 Kfl00131_0170 no hits & (original description: no original description) kfl00131_0170_v1.1 0.8893124576499337 72 Kfl00733_0030 no hits & (original description: no original description) kfl00733_0030_v1.1 0.8887991176714704 73 Kfl00323_0130 (at3g46940 : 221.0) DUTP-PYROPHOSPHATASE-LIKE 1 (DUT1); FUNCTIONS IN: hydrolase activity, dUTP diphosphatase activity; INVOLVED IN: DNA repair, 2'-deoxyribonucleotide metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DeoxyUTP pyrophosphatase domain, subfamily 1, (InterPro:IPR008181), DeoxyUTP pyrophosphatase domain (InterPro:IPR008180); Has 7764 Blast hits to 7750 proteins in 2463 species: Archae - 14; Bacteria - 4311; Metazoa - 248; Fungi - 161; Plants - 56; Viruses - 831; Other Eukaryotes - 2143 (source: NCBI BLink). & (reliability: 442.0) & (original description: no original description) kfl00323_0130_v1.1 0.888015376274248 94 Kfl00028_g56 (at2g27960 : 105.0) catalytic subunit of cyclin dependent kinase 1. physically interact with cyclin-dependent kinases (CDKs) and play an essential, but yet not entirely resolved, role in the regulation of the cell cycle; cyclin-dependent kinase-subunit 1 (CKS1); CONTAINS InterPro DOMAIN/s: Cyclin-dependent kinase, regulatory subunit (InterPro:IPR000789); BEST Arabidopsis thaliana protein match is: CDK-subunit 2 (TAIR:AT2G27970.1); Has 657 Blast hits to 657 proteins in 207 species: Archae - 0; Bacteria - 0; Metazoa - 305; Fungi - 139; Plants - 105; Viruses - 0; Other Eukaryotes - 108 (source: NCBI BLink). & (reliability: 210.0) & (original description: no original description) kfl00028_g56_v1.1 0.8878204318705442 76 Kfl00302_0030 (at1g67780 : 163.0) Zinc-finger domain of monoamine-oxidase A repressor R1 protein; CONTAINS InterPro DOMAIN/s: DDT domain superfamily (InterPro:IPR018501), DDT domain, subgroup (InterPro:IPR018500), Cell division cycle-associated protein (InterPro:IPR018866); BEST Arabidopsis thaliana protein match is: Zinc-finger domain of monoamine-oxidase A repressor R1 protein (TAIR:AT1G67270.1); Has 462 Blast hits to 453 proteins in 104 species: Archae - 0; Bacteria - 0; Metazoa - 139; Fungi - 73; Plants - 215; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink). & (reliability: 326.0) & (original description: no original description) kfl00302_0030_v1.1 0.88761835061013 76 Kfl00217_0140 no hits & (original description: no original description) kfl00217_0140_v1.1 0.8872019458900737 77 Kfl00086_0370 (at3g05740 : 520.0) RECQ helicase l1 (RECQI1); FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: DNA recombination; LOCATED IN: cellular_component unknown; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DNA helicase (RECQl4A) (TAIR:AT1G10930.1); Has 22913 Blast hits to 22836 proteins in 2673 species: Archae - 358; Bacteria - 13443; Metazoa - 2936; Fungi - 2132; Plants - 1261; Viruses - 9; Other Eukaryotes - 2774 (source: NCBI BLink). & (reliability: 1040.0) & (original description: no original description) kfl00086_0370_v1.1 0.8869064052543956 78 Kfl00137_0140 no hits & (original description: no original description) kfl00137_0140_v1.1 0.886447651069543 79 Kfl00110_0210 no hits & (original description: no original description) kfl00110_0210_v1.1 0.8842795052931194 80 Kfl00242_0010 (at1g08130 : 782.0) Encodes the Arabidopsis DNA ligase 1 that provides the major DNA ligase activity in cells and plays a key role in both DNA replication and excision repair pathways. Indispensable for cell viability. AtLIG1 expresses one major and two minor mRNA transcripts differing only in the length of the 5' untranslated leader sequences preceding a common ORF. Translation from the first in-frame start codon produces an AtLIG1 isoform that is targeted exclusively to the mitochondria. Translation initiation from the second in-frame start codon produces an AtLIG1 isoform targeted only to the nucleus.; DNA ligase 1 (LIG1); FUNCTIONS IN: DNA binding, DNA ligase (ATP) activity, ATP binding; INVOLVED IN: DNA repair, DNA replication, DNA recombination; LOCATED IN: mitochondrion, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA ligase, N-terminal (InterPro:IPR012308), ATP dependent DNA ligase, central (InterPro:IPR012310), ATP dependent DNA ligase, C-terminal (InterPro:IPR012309), ATP-dependent DNA ligase (InterPro:IPR000977), ATP-dependent DNA ligase, conserved site (InterPro:IPR016059); BEST Arabidopsis thaliana protein match is: ATP-dependent DNA ligase (TAIR:AT1G49250.1); Has 3556 Blast hits to 3521 proteins in 879 species: Archae - 298; Bacteria - 1538; Metazoa - 375; Fungi - 434; Plants - 112; Viruses - 159; Other Eukaryotes - 640 (source: NCBI BLink). & (q7x7e9|dnl4_orysa : 110.0) Putative DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) - Oryza sativa (Rice) & (reliability: 1564.0) & (original description: no original description) kfl00242_0010_v1.1 0.8814224796709994 81 Kfl00053_0050 (p08437|h3_volca : 147.0) Histone H3 - Volvox carteri & (at5g10980 : 146.0) Histone superfamily protein; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleosome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Histone H3 (InterPro:IPR000164), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT4G40030.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description) kfl00053_0050_v1.1 0.8810242845437868 82 Kfl00052_0340 (at5g22110 : 456.0) Encodes a protein with similarity to DNA polymerase epsilon subunit B an essential gene that is required for DNA replication. Homozygous mutants are embryo lethal. Expressed in meristematic , rapidly dividing regions.; DNA polymerase epsilon subunit B2 (DPB2); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding; INVOLVED IN: DNA replication, DNA-dependent DNA replication; LOCATED IN: epsilon DNA polymerase complex, nucleus; EXPRESSED IN: embryo, male gametophyte, apical meristem, female gametophyte; CONTAINS InterPro DOMAIN/s: DNA polymerase epsilon, subunit B (InterPro:IPR016266), DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 412 Blast hits to 394 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 125; Fungi - 144; Plants - 62; Viruses - 0; Other Eukaryotes - 81 (source: NCBI BLink). & (reliability: 912.0) & (original description: no original description) kfl00052_0340_v1.1 0.8806746299989674 83 Kfl00031_0280 (at5g26680 : 491.0) 5'-3' exonuclease family protein; FUNCTIONS IN: 5'-3' exonuclease activity, DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, N-terminal (InterPro:IPR002421), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G29630.2); Has 3563 Blast hits to 3243 proteins in 839 species: Archae - 284; Bacteria - 855; Metazoa - 643; Fungi - 727; Plants - 266; Viruses - 42; Other Eukaryotes - 746 (source: NCBI BLink). & (q9sxq6|fen1a_orysa : 477.0) Flap endonuclease 1a (EC 3.1.-.-) (OsFEN-1a) - Oryza sativa (Rice) & (reliability: 982.0) & (original description: no original description) kfl00031_0280_v1.1 0.8795857877665151 85 Kfl00113_0300 (at4g29170 : 166.0) A homolog of yeast, mouse and human mnd1delta protein. Null mutants exhibit normal vegetative and flower development; however, during prophase I, chromosomes become fragmented resulting in random distribution of the fragments between polyads. Both male and female meiosis are defective and strong accumulation of AtRAD51 was observed in the inflorescence nuclei of mutant plants. Similarly to its yeast and animal homologues, AtMnd1 might play a role in DSB repair during meiosis.; ATMND1; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: double-strand break repair, embryo sac development, response to ionizing radiation, pollen development; LOCATED IN: cellular_component unknown; EXPRESSED IN: 12 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Meiotic nuclear division protein 1 (InterPro:IPR005647); Has 323 Blast hits to 323 proteins in 161 species: Archae - 0; Bacteria - 2; Metazoa - 88; Fungi - 122; Plants - 42; Viruses - 0; Other Eukaryotes - 69 (source: NCBI BLink). & (reliability: 332.0) & (original description: no original description) kfl00113_0300_v1.1 0.8789756758265442 86 Kfl00348_0110 (at2g39440 : 108.0) CONTAINS InterPro DOMAIN/s: Ribonuclease H2, subunit C (InterPro:IPR013924); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 216.0) & (original description: no original description) kfl00348_0110_v1.1 0.8779021259167324 87 Kfl00539_0100 no hits & (original description: no original description) kfl00539_0100_v1.1 0.8778277969849796 88 Kfl00672_0020 (at2g27170 : 1057.0) Encodes a member of the Arabidopsis cohesin complex that is essential for viability and sister chromatid alignment.; TITAN7 (TTN7); FUNCTIONS IN: ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation; LOCATED IN: cohesin complex, nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 2 (TAIR:AT5G62410.1); Has 158776 Blast hits to 77347 proteins in 3496 species: Archae - 2059; Bacteria - 28403; Metazoa - 67946; Fungi - 11949; Plants - 6773; Viruses - 706; Other Eukaryotes - 40940 (source: NCBI BLink). & (reliability: 2114.0) & (original description: no original description) kfl00672_0020_v1.1 0.8777303586471613 89 Kfl00334_0010 (at2g25100 : 313.0) Polynucleotidyl transferase, ribonuclease H-like superfamily protein; FUNCTIONS IN: ribonuclease H activity, RNA binding, catalytic activity, nucleic acid binding; INVOLVED IN: RNA metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribonuclease H2, subunit A (InterPro:IPR004649), Ribonuclease HII/HIII (InterPro:IPR001352), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); Has 6305 Blast hits to 6298 proteins in 2456 species: Archae - 256; Bacteria - 4469; Metazoa - 152; Fungi - 137; Plants - 56; Viruses - 3; Other Eukaryotes - 1232 (source: NCBI BLink). & (reliability: 626.0) & (original description: no original description) kfl00334_0010_v1.1 0.8775563307819859 90 Kfl00765_0030 (at1g34770 : 128.0) CONTAINS InterPro DOMAIN/s: MAGE protein (InterPro:IPR002190); Has 1274 Blast hits to 1260 proteins in 85 species: Archae - 0; Bacteria - 0; Metazoa - 1104; Fungi - 45; Plants - 49; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink). & (reliability: 256.0) & (original description: no original description) kfl00765_0030_v1.1 0.8774974470684755 91 Kfl00250_0150 (at3g16730 : 121.0) CONTAINS InterPro DOMAIN/s: Non-SMC condensin II complex, subunit H2-like (InterPro:IPR009378); Has 249 Blast hits to 211 proteins in 82 species: Archae - 0; Bacteria - 0; Metazoa - 145; Fungi - 8; Plants - 30; Viruses - 0; Other Eukaryotes - 66 (source: NCBI BLink). & (reliability: 242.0) & (original description: no original description) kfl00250_0150_v1.1 0.8773004519811678 98 Kfl00202_0040 no hits & (original description: no original description) kfl00202_0040_v1.1 0.8762068013018044 95 Kfl00759_0010 (at2g18990 : 239.0) thioredoxin domain-containing protein 9 homolog (TXND9); INVOLVED IN: cell redox homeostasis; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like fold (InterPro:IPR012336), Thioredoxin domain (InterPro:IPR013766); BEST Arabidopsis thaliana protein match is: Thioredoxin superfamily protein (TAIR:AT3G25580.1); Has 1035 Blast hits to 1035 proteins in 264 species: Archae - 10; Bacteria - 75; Metazoa - 396; Fungi - 154; Plants - 221; Viruses - 0; Other Eukaryotes - 179 (source: NCBI BLink). & (reliability: 476.0) & (original description: no original description) kfl00759_0010_v1.1 0.8758246094231431 94 Kfl00022_0250 (at1g21690 : 472.0) embryo defective 1968 (EMB1968); FUNCTIONS IN: in 6 functions; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: DNA replication factor C complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), Replication factor C (InterPro:IPR013748); BEST Arabidopsis thaliana protein match is: replication factor C 2 (TAIR:AT1G63160.1). & (reliability: 944.0) & (original description: no original description) kfl00022_0250_v1.1 0.8754655431134075 95 Kfl00307_0080 no hits & (original description: no original description) kfl00307_0080_v1.1 0.8745844501454744 96 Kfl00416_0020 (at1g11870 : 578.0) Seryl-tRNA synthetase targeted to chloroplasts and mitochondria. Its inactivation causes developmental arrest of chloroplasts and mitochondria in Nicotiana benthamiana.; Seryl-tRNA synthetase (SRS); FUNCTIONS IN: serine-tRNA ligase activity; INVOLVED IN: chloroplast organization, mitochondrion organization, seryl-tRNA aminoacylation, tRNA aminoacylation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: tRNA-binding arm (InterPro:IPR010978), Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain (InterPro:IPR002314), Seryl-tRNA synthetase, class IIa, N-terminal (InterPro:IPR015866), Seryl-tRNA synthetase, class IIa (InterPro:IPR002317), Ubiquitin supergroup (InterPro:IPR019955), Aminoacyl-tRNA synthetase, class II, conserved domain (InterPro:IPR006195), Seryl-tRNA synthetase, class IIa, C-terminal (InterPro:IPR018156); BEST Arabidopsis thaliana protein match is: seryl-tRNA synthetase / serine--tRNA ligase (TAIR:AT5G27470.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (o81983|sys_helan : 223.0) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS) - Helianthus annuus (Common sunflower) & (reliability: 1156.0) & (original description: no original description) kfl00416_0020_v1.1 0.8721134664987652 98 Kfl00110_0200 no hits & (original description: no original description) kfl00110_0200_v1.1 0.8718553422148251 99 Kfl00111_0070 (at1g02970 : 270.0) Protein kinase that negatively regulates the entry into mitosis.; WEE1 kinase homolog (WEE1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT4G19110.2); Has 100256 Blast hits to 98965 proteins in 4396 species: Archae - 165; Bacteria - 12308; Metazoa - 39873; Fungi - 10996; Plants - 18240; Viruses - 408; Other Eukaryotes - 18266 (source: NCBI BLink). & (q5qn75|m2k1_orysa : 92.8) Mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK1) (OsMEK1) - Oryza sativa (Rice) & (reliability: 540.0) & (original description: no original description) kfl00111_0070_v1.1 0.8713683980994417 100