Sequence Description Alias PCC hrr Kfl00425_0030 (at3g18370 : 142.0) ATSYTF; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: Calcium-dependent lipid-binding (CaLB domain) family protein (TAIR:AT5G11100.1); Has 5534 Blast hits to 4008 proteins in 246 species: Archae - 0; Bacteria - 0; Metazoa - 3360; Fungi - 437; Plants - 1305; Viruses - 0; Other Eukaryotes - 432 (source: NCBI BLink). & (reliability: 284.0) & (original description: no original description) kfl00425_0030_v1.1 0.9147447383061241 2 Kfl00117_0160 no hits & (original description: no original description) kfl00117_0160_v1.1 0.9104096396367917 12 Kfl00069_0130 (at5g22010 : 421.0) replication factor C1 (RFC1); FUNCTIONS IN: DNA clamp loader activity, nucleoside-triphosphatase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: DNA replication; LOCATED IN: DNA replication factor C complex, intracellular; CONTAINS InterPro DOMAIN/s: DNA replication factor RFC1, C-terminal (InterPro:IPR013725), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), DNA replication factor C, large subunit (InterPro:IPR012178), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT1G04730.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 842.0) & (original description: no original description) kfl00069_0130_v1.1 0.9083138103495402 34 Kfl00066_0260 (at5g15920 : 686.0) Encodes SMC5 (STRUCTURAL MAINTENANCE OF CHROMOSOMES 5), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.; structural maintenance of chromosomes 5 (SMC5); FUNCTIONS IN: ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT5G61460.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1372.0) & (original description: no original description) kfl00066_0260_v1.1 0.9052970451327457 44 Kfl00131_0170 no hits & (original description: no original description) kfl00131_0170_v1.1 0.9046880316276781 15 Kfl00100_0250 (at1g67320 : 534.0) DNA primase, large subunit family; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, large subunit, eukaryotic (InterPro:IPR016558), DNA primase, large subunit, eukaryotic/archaeal (InterPro:IPR007238). & (reliability: 1068.0) & (original description: no original description) kfl00100_0250_v1.1 0.9020019929603212 81 Kfl00135_0100 (at5g41880 : 457.0) POLA3; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer, DNA replication; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, small subunit (InterPro:IPR002755), DNA primase, small subunit, eukaryotic/archaeal (InterPro:IPR014052); Has 510 Blast hits to 504 proteins in 249 species: Archae - 95; Bacteria - 0; Metazoa - 124; Fungi - 138; Plants - 44; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink). & (reliability: 914.0) & (original description: no original description) kfl00135_0100_v1.1 0.9012930350112432 62 Kfl00302_0040 no hits & (original description: no original description) kfl00302_0040_v1.1 0.8974188144413446 83 Kfl00208_0200 (at3g48540 : 256.0) Cytidine/deoxycytidylate deaminase family protein; FUNCTIONS IN: hydrolase activity, zinc ion binding, catalytic activity; INVOLVED IN: biological_process unknown; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: APOBEC/CMP deaminase, zinc-binding (InterPro:IPR016192), CMP/dCMP deaminase, zinc-binding (InterPro:IPR002125), Cytidine deaminase-like (InterPro:IPR016193), Cytidine deaminase (InterPro:IPR015517); Has 3737 Blast hits to 3733 proteins in 1421 species: Archae - 65; Bacteria - 2323; Metazoa - 218; Fungi - 134; Plants - 52; Viruses - 89; Other Eukaryotes - 856 (source: NCBI BLink). & (reliability: 512.0) & (original description: no original description) kfl00208_0200_v1.1 0.8909040090872707 73 Kfl00007_0060 (at5g01630 : 307.0) Ortholog of breast cancer susceptibility protein 2. Essential at meiosis. Interacts with with both Rad51 and Dss1(I) or both Dmc1 and Dss1(I) in a tripartite complex.; BRCA2-like B (BRCA2B); FUNCTIONS IN: single-stranded DNA binding; INVOLVED IN: meiosis; LOCATED IN: mitochondrion; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), DNA recombination/repair protein BRCA2, helical domain (InterPro:IPR015252), DNA recombination and repair protein, BRCA2 (InterPro:IPR011370), BRCA2, oligonucleotide/oligosaccharide-binding 1 (InterPro:IPR015187), Breast cancer type 2 susceptibility protein (InterPro:IPR015525), BRCA2 repeat (InterPro:IPR002093); BEST Arabidopsis thaliana protein match is: BREAST CANCER 2 like 2A (TAIR:AT4G00020.1); Has 281 Blast hits to 210 proteins in 91 species: Archae - 0; Bacteria - 4; Metazoa - 134; Fungi - 18; Plants - 61; Viruses - 0; Other Eukaryotes - 64 (source: NCBI BLink). & (reliability: 614.0) & (original description: no original description) kfl00007_0060_v1.1 0.8887242794251331 70 Kfl00608_0090 (at5g61460 : 571.0) Encodes SMC6B (STRUCTURAL MAINTENANCE OF CHROMOSOMES 6B), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.; hypersensitive to MMS, irradiation and MMC (MIM); FUNCTIONS IN: ATP binding; INVOLVED IN: double-strand break repair, sister chromatid cohesion, chromosome segregation, response to X-ray, double-strand break repair via homologous recombination; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 6A (TAIR:AT5G07660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1142.0) & (original description: no original description) kfl00608_0090_v1.1 0.8883761882610347 90 Kfl00031_0310 (at2g05210 : 102.0) Encodes AtPOT1a, an accessory factor for telomerase required for positive telomere length regulation. Note on nomenclature: different names have been given to Arabidopsis POT-like genes (Kuchar and Fajkus, 2004; Shakirov et al, 2005; Tani and Murata, 2005). According to a unifying nomenclature (Surovtseva et al, 2007), At2g05210 (previously named AtPOT1) is designated AtPOT1a, while At5g06310 (previously named AtPOT2) is designated AtPOT1b.; Protection of Telomeres 1a (AtPOT1a); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Telomere end binding protein (InterPro:IPR011564); BEST Arabidopsis thaliana protein match is: Nucleic acid-binding, OB-fold-like protein (TAIR:AT5G06310.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 204.0) & (original description: no original description) kfl00031_0310_v1.1 0.8881782611550775 89 Kfl00211_0100 (at4g09020 : 951.0) Encodes an isoamylase-like protein. Mutant studies show that the gene is strongly involved in starch breakdown. A GUS-protein fusion product was shown to localize to the surface of chloroplastic structures reminiscent of starch granules. In the mutants, the chloroplastic α-amylase AMY3 is upregulated.; isoamylase 3 (ISA3); FUNCTIONS IN: isoamylase activity, alpha-amylase activity; INVOLVED IN: carbohydrate metabolic process, starch catabolic process; LOCATED IN: chloroplast, chloroplast stroma, chloroplast starch grain; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycosyl hydrolase, family 13, all-beta (InterPro:IPR013780), Immunoglobulin-like fold (InterPro:IPR013783), Glycoside hydrolase, family 13, N-terminal (InterPro:IPR004193), Immunoglobulin E-set (InterPro:IPR014756), Glycoside hydrolase, catalytic core (InterPro:IPR017853), Glycoside hydrolase, subgroup, catalytic core (InterPro:IPR013781), Glycosyl hydrolase, family 13, catalytic domain (InterPro:IPR006047); BEST Arabidopsis thaliana protein match is: isoamylase 1 (TAIR:AT2G39930.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1902.0) & (original description: no original description) kfl00211_0100_v1.1 0.8876057811117588 29 Kfl00110_0200 no hits & (original description: no original description) kfl00110_0200_v1.1 0.8869793362578204 42 Kfl00203_0160 (at1g10930 : 726.0) DNA helicase involved in the maintenance of genome stability by modulation of the DNA damage response and suppression of homologous recombination.; RECQ4A; FUNCTIONS IN: helicase activity, ATP-dependent 3'-5' DNA helicase activity, ATP-dependent helicase activity, nucleic acid binding, ATP binding; INVOLVED IN: chromosome organization, response to DNA damage stimulus, double-strand break repair via homologous recombination; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), RQC domain (InterPro:IPR018982), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), Helicase/RNase D C-terminal, HRDC domain (InterPro:IPR002121); BEST Arabidopsis thaliana protein match is: RECQ helicase L4B (TAIR:AT1G60930.1); Has 34923 Blast hits to 34782 proteins in 2821 species: Archae - 633; Bacteria - 21324; Metazoa - 3687; Fungi - 2728; Plants - 1606; Viruses - 18; Other Eukaryotes - 4927 (source: NCBI BLink). & (reliability: 1452.0) & (original description: no original description) kfl00203_0160_v1.1, kfl00203_0160_v1.1 0.8848415111270485 56 Kfl00759_0050 no hits & (original description: no original description) kfl00759_0050_v1.1 0.8830888093002324 59 Kfl00224_0030 no hits & (original description: no original description) kfl00224_0030_v1.1 0.8816280240884785 18 Kfl00647_0030 (at2g37210 : 233.0) Encodes a protein of unknown function. It has been crystallized and shown to be structurally almost identical to the protein encoded by At5g11950.; lysine decarboxylase family protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: Conserved hypothetical protein CHP00730 (InterPro:IPR005269); BEST Arabidopsis thaliana protein match is: Putative lysine decarboxylase family protein (TAIR:AT3G53450.1). & (reliability: 452.0) & (original description: no original description) kfl00647_0030_v1.1 0.8816253479710753 19 Kfl00055_0170 (at3g57060 : 412.0) binding; FUNCTIONS IN: binding; INVOLVED IN: mitosis, chromosome condensation; LOCATED IN: nucleus, condensin complex; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Non-SMC condensin subunit, XCAP-D2/Cnd1 (InterPro:IPR007673), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: binding (TAIR:AT4G15890.1). & (reliability: 824.0) & (original description: no original description) kfl00055_0170_v1.1 0.8805559331479967 94 Kfl00072_0060 (at1g57820 : 631.0) Encodes a 645-amino acid methylcytosine-binding protein with a PHD domain, two RING finger domains, and an SRA domain that is involved in centromere heterochromatinization. This protein functions as an E3 ubiquitin ligase in vitro. The protein has been shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the former. It plays a role in the establishment/maintenance of chromatin structure during cell division and is localized in the nucleus. Plants over-expressing VIM1/ORTH2 show an inhibition in root growth and a delay in flowering. Both over-expression of GFP:ORTH2 and loss of ORTH2/VIM1 lead to decreased levels of DNA methylation. GFP:ORTH2 over-expressers also have increased levels of FWA transcripts.; VARIANT IN METHYLATION 1 (VIM1); CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), SRA-YDG (InterPro:IPR003105), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57800.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1262.0) & (original description: no original description) kfl00072_0060_v1.1, kfl00072_0060_v1.1 0.8794498687229108 98 Kfl00700_0040 (at1g76260 : 316.0) DWD (DDB1-binding WD40 protein) hypersensitive to ABA 2 (DWA2); CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT1G20540.1); Has 7905 Blast hits to 6688 proteins in 412 species: Archae - 0; Bacteria - 764; Metazoa - 3555; Fungi - 1654; Plants - 1112; Viruses - 0; Other Eukaryotes - 820 (source: NCBI BLink). & (reliability: 632.0) & (original description: no original description) kfl00700_0040_v1.1 0.8763445506824792 44 Kfl00561_0040 no hits & (original description: no original description) kfl00561_0040_v1.1 0.8760942196760805 92 Kfl00416_0020 (at1g11870 : 578.0) Seryl-tRNA synthetase targeted to chloroplasts and mitochondria. Its inactivation causes developmental arrest of chloroplasts and mitochondria in Nicotiana benthamiana.; Seryl-tRNA synthetase (SRS); FUNCTIONS IN: serine-tRNA ligase activity; INVOLVED IN: chloroplast organization, mitochondrion organization, seryl-tRNA aminoacylation, tRNA aminoacylation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: tRNA-binding arm (InterPro:IPR010978), Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain (InterPro:IPR002314), Seryl-tRNA synthetase, class IIa, N-terminal (InterPro:IPR015866), Seryl-tRNA synthetase, class IIa (InterPro:IPR002317), Ubiquitin supergroup (InterPro:IPR019955), Aminoacyl-tRNA synthetase, class II, conserved domain (InterPro:IPR006195), Seryl-tRNA synthetase, class IIa, C-terminal (InterPro:IPR018156); BEST Arabidopsis thaliana protein match is: seryl-tRNA synthetase / serine--tRNA ligase (TAIR:AT5G27470.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (o81983|sys_helan : 223.0) Seryl-tRNA synthetase (EC 6.1.1.11) (Serine--tRNA ligase) (SerRS) - Helianthus annuus (Common sunflower) & (reliability: 1156.0) & (original description: no original description) kfl00416_0020_v1.1 0.8736869648277759 46 Kfl00327_0060 (at4g32700 : 819.0) Encodes a homolog of Drosophila MUS308 and mammalian DNA polymerase, which prevent spontaneous or DNA damage-induced production of DNA double strand breaks. Two conserved functional domains: an N-terminal superfamily II DNA/RNA helicase domain and a C-terminal prokaryotic-type DNA polymerase I domain. Required for regulated cell division and differentiation in meristems. Mutant plants show morphological defects, such as short roots, serrated leaves, and fasciation, as well as defective patterns of cell division and differentiation in the meristem. Mutant plants had 2.5 to 4.5-fold higher expression of ATGR1, ATBRCA1 and RAD51 genes. TEB is required for normal progression of DNA replication and for correct expression of genes during development.; helicases;ATP-dependent helicases;nucleic acid binding;ATP binding;DNA-directed DNA polymerases;DNA binding; FUNCTIONS IN: in 6 functions; INVOLVED IN: regulation of gene expression, DNA replication, DNA recombination, photomorphogenesis; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA-directed DNA polymerase, family A, palm domain (InterPro:IPR001098), DNA/RNA helicase, C-terminal (InterPro:IPR001650), DNA polymerase A domain (InterPro:IPR002298), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: U5 small nuclear ribonucleoprotein helicase (TAIR:AT2G42270.1); Has 17628 Blast hits to 16579 proteins in 2941 species: Archae - 600; Bacteria - 7507; Metazoa - 1254; Fungi - 1190; Plants - 590; Viruses - 412; Other Eukaryotes - 6075 (source: NCBI BLink). & (reliability: 1638.0) & (original description: no original description) kfl00327_0060_v1.1 0.8724277569443906 79 Kfl00144_0180 (at1g24470 : 90.5) Encodes one of the two Arabidopsis homologues to YBR159w encoding a S. cerevisiae beta-ketoacyl reductase (KCR), which catalyzes the first reduction during VLCFA (very long chain fatty acids, >18 carbon) elongation: KCR1 (At1g67730), KCR2 (At1g24470). Complementation of the yeast ybr159Delta mutant demonstrated that the two KCR proteins are divergent and that only AtKCR1 can restore heterologous elongase activity similar to the native yeast KCR gene.; beta-ketoacyl reductase 2 (KCR2); FUNCTIONS IN: oxidoreductase activity, ketoreductase activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: endoplasmic reticulum; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Short-chain dehydrogenase/reductase, conserved site (InterPro:IPR020904), NAD(P)-binding domain (InterPro:IPR016040), Glucose/ribitol dehydrogenase (InterPro:IPR002347), Short-chain dehydrogenase/reductase SDR (InterPro:IPR002198); BEST Arabidopsis thaliana protein match is: beta-ketoacyl reductase 1 (TAIR:AT1G67730.1); Has 80088 Blast hits to 80001 proteins in 3265 species: Archae - 726; Bacteria - 55481; Metazoa - 4714; Fungi - 3206; Plants - 2039; Viruses - 0; Other Eukaryotes - 13922 (source: NCBI BLink). & (reliability: 181.0) & (original description: no original description) kfl00144_0180_v1.1, kfl00144_0180_v1.1 0.8716037464297035 41 Kfl00053_0050 (p08437|h3_volca : 147.0) Histone H3 - Volvox carteri & (at5g10980 : 146.0) Histone superfamily protein; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleosome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Histone H3 (InterPro:IPR000164), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT4G40030.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description) kfl00053_0050_v1.1 0.8707841894573629 78 Kfl00130_0130 (at5g27740 : 530.0) A locus involved in embryogenesis. Mutations in this locus result in embryo lethality.; EMBRYO DEFECTIVE 2775 (EMB2775); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp-loader complex, subunit E, C-terminal (InterPro:IPR019483), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921); BEST Arabidopsis thaliana protein match is: ATPase family associated with various cellular activities (AAA) (TAIR:AT1G21690.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1060.0) & (original description: no original description) kfl00130_0130_v1.1 0.8689663200377362 64 Kfl00062_0110 (at4g01160 : 99.8) BTB/POZ/Kelch-associated protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/Kelch-associated (InterPro:IPR011705), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: POZ/BTB containin G-protein 1 (TAIR:AT3G61600.2); Has 3481 Blast hits to 3463 proteins in 124 species: Archae - 0; Bacteria - 0; Metazoa - 3173; Fungi - 4; Plants - 136; Viruses - 49; Other Eukaryotes - 119 (source: NCBI BLink). & (reliability: 199.6) & (original description: no original description) kfl00062_0110_v1.1 0.8685722372381223 96 Kfl00307_0080 no hits & (original description: no original description) kfl00307_0080_v1.1 0.8677790149124732 68 Kfl00038_0210 (at3g27120 : 445.0) P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 6 plant structures; EXPRESSED DURING: F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, conserved site (InterPro:IPR003960), Vps4 oligomerisation, C-terminal (InterPro:IPR015415); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT3G27130.1); Has 33109 Blast hits to 30842 proteins in 3139 species: Archae - 1459; Bacteria - 13342; Metazoa - 4781; Fungi - 3652; Plants - 2738; Viruses - 26; Other Eukaryotes - 7111 (source: NCBI BLink). & (q96372|cdc48_capan : 131.0) Cell division cycle protein 48 homolog - Capsicum annuum (Bell pepper) & (reliability: 890.0) & (original description: no original description) kfl00038_0210_v1.1 0.8651160359322191 35 Kfl00862_0010 (at1g09430 : 619.0) Encodes subunit A of the heteromeric enzyme ATP citrate lyase (ACL). In animals, ACL is encoded by a single gene; ACL in Arabidopsis is composed of two polypeptides, ACLA (encoded by 3 genes) and ACLB (encoded by 2 genes). The holoenzyme has an A(4)B(4)stoichiometry. Expression of both ACLA and ACLB but not of either of the subunits alone results in ACL activity.; ATP-citrate lyase A-3 (ACLA-3); CONTAINS InterPro DOMAIN/s: ATP-grasp fold, subdomain 2 (InterPro:IPR013816), ATP-grasp fold, succinyl-CoA synthetase-type (InterPro:IPR013650), Succinyl-CoA synthetase-like (InterPro:IPR016102); BEST Arabidopsis thaliana protein match is: ATP-citrate lyase A-1 (TAIR:AT1G10670.4); Has 5303 Blast hits to 5302 proteins in 1635 species: Archae - 133; Bacteria - 3235; Metazoa - 230; Fungi - 139; Plants - 96; Viruses - 0; Other Eukaryotes - 1470 (source: NCBI BLink). & (reliability: 1238.0) & (original description: no original description) kfl00862_0010_v1.1 0.8604170338464674 39 Kfl00170_0070 (at4g30710 : 141.0) Family of unknown function (DUF566) ; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF566 (InterPro:IPR007573); BEST Arabidopsis thaliana protein match is: Family of unknown function (DUF566) (TAIR:AT2G24070.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 282.0) & (original description: no original description) kfl00170_0070_v1.1 0.8592267707610197 40 Kfl00213_0020 (at4g14385 : 114.0) FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Histone H4 acetyltransferase, NuA4 complex, Eaf6 (InterPro:IPR015418); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 228.0) & (original description: no original description) kfl00213_0020_v1.1 0.8579317481954608 52 Kfl00007_0070 (at1g59600 : 87.0) ZCW7; Has 136 Blast hits to 136 proteins in 53 species: Archae - 0; Bacteria - 0; Metazoa - 101; Fungi - 0; Plants - 35; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink). & (reliability: 174.0) & (original description: no original description) kfl00007_0070_v1.1 0.8578584194154716 78 Kfl00001_0700 no hits & (original description: no original description) kfl00001_0700_v1.1 0.8568437004760188 54 Kfl00640_0020 (at1g80380 : 354.0) encodes a glycerate kinase which catalyzes the last step of photorespiration C2 cycle.; P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: glycerate kinase activity; INVOLVED IN: photorespiration; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages. & (reliability: 708.0) & (original description: no original description) kfl00640_0020_v1.1 0.852213264153186 97 Kfl00026_0260 (q9xfh3|mad2_maize : 253.0) Mitotic spindle checkpoint protein MAD2 - Zea mays (Maize) & (at3g25980 : 249.0) Encodes MAD2 (MITOTIC ARREST-DEFICIENT 2). May have the spindle assembly checkpoint protein functions conserved from yeast to humans.; MITOTIC ARREST-DEFICIENT 2 (MAD2); CONTAINS InterPro DOMAIN/s: DNA-binding HORMA (InterPro:IPR003511). & (reliability: 498.0) & (original description: no original description) kfl00026_0260_v1.1 0.8521499791129677 52 Kfl00637_0040 no hits & (original description: no original description) kfl00637_0040_v1.1 0.8488729091892931 57 Kfl00078_0080 no hits & (original description: no original description) kfl00078_0080_v1.1 0.8488000146805637 58 Kfl00057_0090 (at2g22140 : 132.0) Forms a complex with MUS81 that functions as endonuclease in DNA recombination and repair processes.; essential meiotic endonuclease 1B (EME1B); CONTAINS InterPro DOMAIN/s: ERCC4 domain (InterPro:IPR006166); BEST Arabidopsis thaliana protein match is: essential meiotic endonuclease 1A (TAIR:AT2G21800.1); Has 542 Blast hits to 486 proteins in 142 species: Archae - 0; Bacteria - 42; Metazoa - 170; Fungi - 104; Plants - 48; Viruses - 0; Other Eukaryotes - 178 (source: NCBI BLink). & (reliability: 264.0) & (original description: no original description) kfl00057_0090_v1.1 0.8468343749647743 88 Kfl00309_0170 (at5g63920 : 891.0) Encodes topoisomerase 3alpha. Suppresses somatic crossovers. Essential for resolution of meiotic recombination intermediates.; topoisomerase 3alpha (TOP3A); FUNCTIONS IN: DNA topoisomerase activity, DNA topoisomerase type I activity, DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: in 7 processes; LOCATED IN: chromosome; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA topoisomerase, type IA, zn finger (InterPro:IPR013498), DNA topoisomerase, type IA, core (InterPro:IPR000380), DNA topoisomerase, type IA, domain 2 (InterPro:IPR003601), DNA topoisomerase, type IA, DNA-binding (InterPro:IPR003602), DNA topoisomerase, type IA, central (InterPro:IPR013497), Zinc finger, GRF-type (InterPro:IPR010666), DNA topoisomerase, type IA, central region, subdomain 3 (InterPro:IPR013826), Toprim domain, subgroup (InterPro:IPR006154), DNA topoisomerase, type IA, central region, subdomain 1 (InterPro:IPR013824), Toprim domain (InterPro:IPR006171), Zinc finger, CCHC-type (InterPro:IPR001878); BEST Arabidopsis thaliana protein match is: DNA topoisomerase, type IA, core (TAIR:AT2G32000.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1782.0) & (original description: no original description) kfl00309_0170_v1.1 0.8464204692981792 77 Kfl00121_0070 (at4g33760 : 739.0) tRNA synthetase class II (D, K and N) family protein; FUNCTIONS IN: in 6 functions; INVOLVED IN: aspartyl-tRNA aminoacylation, translation, tRNA aminoacylation for protein translation; LOCATED IN: mitochondrion, chloroplast, membrane, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Aspartyl/Asparaginyl-tRNA synthetase, class IIb (InterPro:IPR002312), Aminoacyl-tRNA synthetase, class II, conserved domain (InterPro:IPR006195), Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type (InterPro:IPR004524), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Aminoacyl-tRNA synthetase, class II (D/K/N) (InterPro:IPR004364), Aminoacyl-tRNA synthetase, class II (D/K/N)-like (InterPro:IPR018150), Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type, C-terminal (InterPro:IPR018153), GAD domain (InterPro:IPR004115); BEST Arabidopsis thaliana protein match is: Lysyl-tRNA synthetase, class II (TAIR:AT3G13490.1); Has 31429 Blast hits to 23398 proteins in 2969 species: Archae - 812; Bacteria - 21040; Metazoa - 874; Fungi - 1027; Plants - 329; Viruses - 0; Other Eukaryotes - 7347 (source: NCBI BLink). & (reliability: 1478.0) & (original description: no original description) kfl00121_0070_v1.1 0.8459055749123174 92 Kfl00456_0120 no hits & (original description: no original description) kfl00456_0120_v1.1 0.8452215244665058 96 Kfl00302_0110 (at4g02740 : 114.0) F-box/RNI-like superfamily protein; CONTAINS InterPro DOMAIN/s: F-box domain, Skp2-like (InterPro:IPR022364); BEST Arabidopsis thaliana protein match is: RNI-like superfamily protein (TAIR:AT4G02760.2); Has 1857 Blast hits to 1364 proteins in 199 species: Archae - 3; Bacteria - 120; Metazoa - 715; Fungi - 206; Plants - 319; Viruses - 25; Other Eukaryotes - 469 (source: NCBI BLink). & (reliability: 228.0) & (original description: no original description) kfl00302_0110_v1.1 0.8447513013283294 67 Kfl00281_0130 no hits & (original description: no original description) kfl00281_0130_v1.1 0.8447443021642277 95 Kfl00434_0050 no hits & (original description: no original description) kfl00434_0050_v1.1 0.8420174248302077 77 Kfl00029_0220 (at4g17370 : 424.0) Oxidoreductase family protein; FUNCTIONS IN: oxidoreductase activity, binding, catalytic activity; INVOLVED IN: oxidation reduction, metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Oxidoreductase, N-terminal (InterPro:IPR000683), Oxidoreductase, C-terminal (InterPro:IPR004104), NAD(P)-binding domain (InterPro:IPR016040); Has 13319 Blast hits to 13319 proteins in 1855 species: Archae - 262; Bacteria - 9244; Metazoa - 179; Fungi - 353; Plants - 43; Viruses - 0; Other Eukaryotes - 3238 (source: NCBI BLink). & (reliability: 848.0) & (original description: no original description) kfl00029_0220_v1.1 0.8417623144513685 78 Kfl00079_0180 (at4g34620 : 85.5) Encodes ribosomal protein S16, has embryo-defective lethal mutant phenotype; small subunit ribosomal protein 16 (SSR16); FUNCTIONS IN: structural constituent of ribosome; INVOLVED IN: translation, ribosome biogenesis, embryo development ending in seed dormancy; LOCATED IN: ribosome, chloroplast, plastid, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal protein S16 (InterPro:IPR000307); BEST Arabidopsis thaliana protein match is: Ribosomal protein S16 family protein (TAIR:AT5G56940.1); Has 8683 Blast hits to 8683 proteins in 3031 species: Archae - 0; Bacteria - 5404; Metazoa - 128; Fungi - 129; Plants - 717; Viruses - 0; Other Eukaryotes - 2305 (source: NCBI BLink). & (reliability: 171.0) & (original description: no original description) kfl00079_0180_v1.1 0.8398306772732457 84 Kfl00029_0390 no hits & (original description: no original description) kfl00029_0390_v1.1 0.83829283566893 85 Kfl00081_0160 (at4g33670 : 392.0) Encodes a L-galactose dehydrogenase, involved in ascorbate biosynthesis; NAD(P)-linked oxidoreductase superfamily protein; CONTAINS InterPro DOMAIN/s: Aldo/keto reductase (InterPro:IPR001395); BEST Arabidopsis thaliana protein match is: NAD(P)-linked oxidoreductase superfamily protein (TAIR:AT1G60750.1); Has 28637 Blast hits to 28630 proteins in 2499 species: Archae - 653; Bacteria - 20546; Metazoa - 1049; Fungi - 1796; Plants - 827; Viruses - 0; Other Eukaryotes - 3766 (source: NCBI BLink). & (p40691|a115_tobac : 99.4) Auxin-induced protein PCNT115 - Nicotiana tabacum (Common tobacco) & (reliability: 784.0) & (original description: no original description) kfl00081_0160_v1.1 0.8362703278654507 91 Kfl00839_0060 (at3g05420 : 80.1) Acyl-CoA binding protein with high affinity for oleoyl-CoA. Expressed in all plant organs. Involved in fatty acid transport.; acyl-CoA binding protein 4 (ACBP4); FUNCTIONS IN: acyl-CoA binding; INVOLVED IN: lipid transport; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 2 (InterPro:IPR011498), Acyl-CoA-binding protein, ACBP (InterPro:IPR000582), Kelch-type beta propeller (InterPro:IPR015915), FERM/acyl-CoA-binding protein, 3-helical bundle (InterPro:IPR014352); BEST Arabidopsis thaliana protein match is: acyl-CoA binding protein 5 (TAIR:AT5G27630.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 160.2) & (original description: no original description) kfl00839_0060_v1.1 0.8356394707482859 93 Kfl00111_0070 (at1g02970 : 270.0) Protein kinase that negatively regulates the entry into mitosis.; WEE1 kinase homolog (WEE1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: Protein kinase superfamily protein (TAIR:AT4G19110.2); Has 100256 Blast hits to 98965 proteins in 4396 species: Archae - 165; Bacteria - 12308; Metazoa - 39873; Fungi - 10996; Plants - 18240; Viruses - 408; Other Eukaryotes - 18266 (source: NCBI BLink). & (q5qn75|m2k1_orysa : 92.8) Mitogen-activated protein kinase kinase 1 (EC 2.7.12.2) (MAP kinase kinase 1) (MAPKK1) (OsMEK1) - Oryza sativa (Rice) & (reliability: 540.0) & (original description: no original description) kfl00111_0070_v1.1 0.8335625569548135 97 Kfl00242_0010 (at1g08130 : 782.0) Encodes the Arabidopsis DNA ligase 1 that provides the major DNA ligase activity in cells and plays a key role in both DNA replication and excision repair pathways. Indispensable for cell viability. AtLIG1 expresses one major and two minor mRNA transcripts differing only in the length of the 5' untranslated leader sequences preceding a common ORF. Translation from the first in-frame start codon produces an AtLIG1 isoform that is targeted exclusively to the mitochondria. Translation initiation from the second in-frame start codon produces an AtLIG1 isoform targeted only to the nucleus.; DNA ligase 1 (LIG1); FUNCTIONS IN: DNA binding, DNA ligase (ATP) activity, ATP binding; INVOLVED IN: DNA repair, DNA replication, DNA recombination; LOCATED IN: mitochondrion, nucleus; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA ligase, N-terminal (InterPro:IPR012308), ATP dependent DNA ligase, central (InterPro:IPR012310), ATP dependent DNA ligase, C-terminal (InterPro:IPR012309), ATP-dependent DNA ligase (InterPro:IPR000977), ATP-dependent DNA ligase, conserved site (InterPro:IPR016059); BEST Arabidopsis thaliana protein match is: ATP-dependent DNA ligase (TAIR:AT1G49250.1); Has 3556 Blast hits to 3521 proteins in 879 species: Archae - 298; Bacteria - 1538; Metazoa - 375; Fungi - 434; Plants - 112; Viruses - 159; Other Eukaryotes - 640 (source: NCBI BLink). & (q7x7e9|dnl4_orysa : 110.0) Putative DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) - Oryza sativa (Rice) & (reliability: 1564.0) & (original description: no original description) kfl00242_0010_v1.1 0.8334615121508494 98 Kfl00299_0060 (p37221|maom_soltu : 666.0) NAD-dependent malic enzyme 62 kDa isoform, mitochondrial precursor (EC 1.1.1.39) (NAD-ME) - Solanum tuberosum (Potato) & (at2g13560 : 653.0) Encodes an NAD-dependent malic enzyme (NAD-ME) that does not act on oxaloacetate, indicating that it belongs to EC 1.1.1.39. It is a member of the alpha family of NAD-MEs in plants. It appears to function as a homodimer or as a heterodimer with the beta-type NAD-ME2 (At4g00570). NAD-ME1 transcript and protein levels are higher during the night than during the day.; NAD-dependent malic enzyme 1 (NAD-ME1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to salt stress, malate metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Malic enzyme, NAD-binding (InterPro:IPR012302), Malic oxidoreductase (InterPro:IPR001891), Malic enzyme, conserved site (InterPro:IPR015884), Malic enzyme, N-terminal (InterPro:IPR012301), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: NAD-dependent malic enzyme 2 (TAIR:AT4G00570.1); Has 9465 Blast hits to 9448 proteins in 2440 species: Archae - 143; Bacteria - 6328; Metazoa - 607; Fungi - 221; Plants - 457; Viruses - 0; Other Eukaryotes - 1709 (source: NCBI BLink). & (reliability: 1306.0) & (original description: no original description) kfl00299_0060_v1.1 0.8334583224069925 99