Sequence Description Alias PCC hrr Kfl00049_0150 no hits & (original description: no original description) kfl00049_0150_v1.1 0.9334554645330533 18 Kfl00771_0050 no hits & (original description: no original description) kfl00771_0050_v1.1 0.9253836177663355 2 Kfl01292_0010 (at2g40550 : 368.0) Encodes a nuclear localized target of E2Fa-DPa, transcription factors controlling cell cycle progression. Required for sister chromatid cohesion and DNA repair.; E2F target gene 1 (ETG1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: sister chromatid cohesion, postreplication repair, DNA replication; LOCATED IN: nuclear replisome, nucleus, chloroplast envelope, MCM complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF2044, membrane (InterPro:IPR019140); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 736.0) & (original description: no original description) kfl01292_0010_v1.1 0.922127173690404 19 Kfl00201_0050 no hits & (original description: no original description) kfl00201_0050_v1.1 0.9175906432804811 35 Kfl00349_0050 (o48653|dpola_orysa : 1124.0) DNA polymerase alpha catalytic subunit (EC 2.7.7.7) - Oryza sativa (Rice) & (at5g67100 : 1019.0) Encodes the putative catalytic subunit of the DNA polymerase alpha. Interacts with genes involved in chromatin-mediated cellular memory. ICU2 genetically interacts with TERMINAL FLOWER2, the ortholog of HETEROCHROMATIN PROTEIN1 of animals and yeasts, and with the Polycomb group (PcG) gene CURLY LEAF. A number of regulatory genes were derepressed in the icu2-1 mutant, including genes associated with flowering time, floral meristem, and floral organ identity. Mutant has curled, involute leaves and causes early flowering.; INCURVATA2 (ICU2); FUNCTIONS IN: DNA-directed DNA polymerase activity; INVOLVED IN: negative regulation of flower development, leaf morphogenesis; LOCATED IN: nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134), Zinc finger, DNA-directed DNA polymerase, family B, alpha (InterPro:IPR015088), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved site (InterPro:IPR017964), DNA-directed DNA polymerase, family B (InterPro:IPR006172), DNA-directed DNA polymerase, family B, pol2 (InterPro:IPR004578); BEST Arabidopsis thaliana protein match is: DNA binding;nucleotide binding;nucleic acid binding;DNA-directed DNA polymerases;DNA-directed DNA polymerases (TAIR:AT5G63960.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 2038.0) & (original description: no original description) kfl00349_0050_v1.1 0.9161524783321413 58 Kfl00033_0050 (at4g24710 : 451.0) P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; EXPRESSED IN: shoot apex, embryo, flower, seed; EXPRESSED DURING: petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, conserved site (InterPro:IPR003960), Chaperonin clpA/B (InterPro:IPR001270); BEST Arabidopsis thaliana protein match is: ATPase, AAA-type, CDC48 protein (TAIR:AT3G53230.1); Has 23595 Blast hits to 21814 proteins in 2884 species: Archae - 1432; Bacteria - 8057; Metazoa - 4130; Fungi - 3211; Plants - 2291; Viruses - 16; Other Eukaryotes - 4458 (source: NCBI BLink). & (reliability: 902.0) & (original description: no original description) kfl00033_0050_v1.1 0.915764885982369 6 Kfl00038_0280 no hits & (original description: no original description) kfl00038_0280_v1.1 0.9135123625673125 28 Kfl00045_0200 (at3g05480 : 323.0) Involved in the regulation of DNA damage repair and homologous recombination.; RAD9; CONTAINS InterPro DOMAIN/s: Rad9 (InterPro:IPR007268), Cell cycle checkpoint, RAD9 (InterPro:IPR016552). & (reliability: 646.0) & (original description: no original description) kfl00045_0200_v1.1 0.9131369232254637 8 Kfl00121_0170 (at5g54260 : 676.0) DNA repair and meiotic recombination protein, component of MRE11 complex with RAD50 and NBS1; MEIOTIC RECOMBINATION 11 (MRE11); FUNCTIONS IN: hydrolase activity, manganese ion binding, protein serine/threonine phosphatase activity, exonuclease activity, endonuclease activity; INVOLVED IN: double-strand break repair, DNA metabolic process; LOCATED IN: nucleus; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 4 anthesis, F mature embryo stage, petal differentiation and expansion stage, E expanded cotyledon stage, D bilateral stage; CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), DNA repair exonuclease (InterPro:IPR003701), Mre11, DNA-binding (InterPro:IPR007281); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1352.0) & (original description: no original description) kfl00121_0170_v1.1 0.9128201352392105 24 Kfl00523_0070 (at5g58230 : 676.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1352.0) & (original description: no original description) kfl00523_0070_v1.1 0.9124489079462004 17 Kfl00029_0270 (at5g44635 : 779.0) MINICHROMOSOME MAINTENANCE 6 (MCM6); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: shoot apex; EXPRESSED DURING: IL.00 inflorescence just visible; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 6 (InterPro:IPR008049); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q43704|mcm3_maize : 281.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1558.0) & (original description: no original description) kfl00029_0270_v1.1 0.9122994377722018 32 Kfl00302_0040 no hits & (original description: no original description) kfl00302_0040_v1.1 0.9076857969611456 64 Kfl00051_0100 no hits & (original description: no original description) kfl00051_0100_v1.1 0.9066261200798964 54 Kfl00481_0090 (at4g02060 : 837.0) Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.; PROLIFERA (PRL); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 7 (InterPro:IPR008050); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1). & (q43704|mcm3_maize : 242.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1674.0) & (original description: no original description) kfl00481_0090_v1.1 0.9058181465899274 52 Kfl00061_0280 (at1g08260 : 1660.0) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 3320.0) & (original description: no original description) kfl00061_0280_v1.1 0.9056079645957578 59 Kfl00125_0130 (at1g63660 : 770.0) GMP synthase (glutamine-hydrolyzing), putative / glutamine amidotransferase, putative; FUNCTIONS IN: asparagine synthase (glutamine-hydrolyzing) activity, GMP synthase (glutamine-hydrolyzing) activity, catalytic activity, ATP binding; INVOLVED IN: GMP biosynthetic process, glutamine metabolic process, biosynthetic process, asparagine biosynthetic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Glutamine amidotransferase class-I, C-terminal (InterPro:IPR000991), Glutamine amidotransferase superfamily (InterPro:IPR011702), GMP synthase, N-terminal (InterPro:IPR004739), Glutamine amidotransferase type 1 (InterPro:IPR017926), Asparagine synthase (InterPro:IPR001962), Anthranilate synthase component II/delta crystallin (InterPro:IPR006220); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 1540.0) & (original description: no original description) kfl00125_0130_v1.1 0.9043997672365471 62 Kfl00067_0060 (at2g01120 : 291.0) Origin Recognition Complex subunit 4. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors. Interacts with all ORC subunits except ORC1b.; origin recognition complex subunit 4 (ORC4); CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Origin recognition complex, subunit 4 (InterPro:IPR016527). & (reliability: 582.0) & (original description: no original description) kfl00067_0060_v1.1 0.901845018509147 32 Kfl00022_0250 (at1g21690 : 472.0) embryo defective 1968 (EMB1968); FUNCTIONS IN: in 6 functions; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: DNA replication factor C complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921), Replication factor C (InterPro:IPR013748); BEST Arabidopsis thaliana protein match is: replication factor C 2 (TAIR:AT1G63160.1). & (reliability: 944.0) & (original description: no original description) kfl00022_0250_v1.1 0.8982650807270536 21 Kfl00130_0230 no hits & (original description: no original description) kfl00130_0230_v1.1 0.8979738295945842 68 Kfl00502_0020 no hits & (original description: no original description) kfl00502_0020_v1.1 0.8970540555731195 42 Kfl00135_0100 (at5g41880 : 457.0) POLA3; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer, DNA replication; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, small subunit (InterPro:IPR002755), DNA primase, small subunit, eukaryotic/archaeal (InterPro:IPR014052); Has 510 Blast hits to 504 proteins in 249 species: Archae - 95; Bacteria - 0; Metazoa - 124; Fungi - 138; Plants - 44; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink). & (reliability: 914.0) & (original description: no original description) kfl00135_0100_v1.1 0.8965895451592442 69 Kfl00052_0340 (at5g22110 : 456.0) Encodes a protein with similarity to DNA polymerase epsilon subunit B an essential gene that is required for DNA replication. Homozygous mutants are embryo lethal. Expressed in meristematic , rapidly dividing regions.; DNA polymerase epsilon subunit B2 (DPB2); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding; INVOLVED IN: DNA replication, DNA-dependent DNA replication; LOCATED IN: epsilon DNA polymerase complex, nucleus; EXPRESSED IN: embryo, male gametophyte, apical meristem, female gametophyte; CONTAINS InterPro DOMAIN/s: DNA polymerase epsilon, subunit B (InterPro:IPR016266), DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 412 Blast hits to 394 proteins in 202 species: Archae - 0; Bacteria - 0; Metazoa - 125; Fungi - 144; Plants - 62; Viruses - 0; Other Eukaryotes - 81 (source: NCBI BLink). & (reliability: 912.0) & (original description: no original description) kfl00052_0340_v1.1 0.8963855346211854 54 Kfl00456_0120 no hits & (original description: no original description) kfl00456_0120_v1.1 0.8958567500713006 23 Kfl00425_0040 (at1g80560 : 526.0) The AtIMD2 is one out of 3 genes encoding the enzyme 3-isopropylmalate dehydrogenase involved in leucine biosynthesis in Arabidopsis. Its subcellular location has been targeted to plastids.; isopropylmalate dehydrogenase 2 (IMD2); FUNCTIONS IN: 3-isopropylmalate dehydrogenase activity; INVOLVED IN: leucine biosynthetic process, metabolic process; LOCATED IN: chloroplast, chloroplast stroma, plastid, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Isopropylmalate dehydrogenase (InterPro:IPR004429), Isocitrate/isopropylmalate dehydrogenase (InterPro:IPR001804), Isocitrate/isopropylmalate dehydrogenase, conserved site (InterPro:IPR019818); BEST Arabidopsis thaliana protein match is: isopropylmalate dehydrogenase 3 (TAIR:AT1G31180.1); Has 15265 Blast hits to 15265 proteins in 2613 species: Archae - 395; Bacteria - 8292; Metazoa - 578; Fungi - 832; Plants - 243; Viruses - 0; Other Eukaryotes - 4925 (source: NCBI BLink). & (p29102|leu3_brana : 521.0) 3-isopropylmalate dehydrogenase, chloroplast precursor (EC 1.1.1.85) (Beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) - Brassica napus (Rape) & (reliability: 1052.0) & (original description: no original description) kfl00425_0040_v1.1, kfl00425_0040_v1.1 0.895524023126889 42 Kfl00998_0030 no hits & (original description: no original description) kfl00998_0030_v1.1 0.8918644188331539 30 Kfl00076_0270 (at2g32240 : 110.0) FUNCTIONS IN: molecular_function unknown; INVOLVED IN: response to cadmium ion; LOCATED IN: plasma membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Prefoldin (InterPro:IPR009053); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G05320.3); Has 470429 Blast hits to 168274 proteins in 4282 species: Archae - 6896; Bacteria - 131956; Metazoa - 175525; Fungi - 33166; Plants - 25441; Viruses - 2243; Other Eukaryotes - 95202 (source: NCBI BLink). & (reliability: 212.0) & (original description: no original description) kfl00076_0270_v1.1, kfl00076_0270_v1.1 0.8911175584471985 83 Kfl00340_0020 (at4g33680 : 587.0) Involved in disease resistance against Pseudomonas syringae. mutants have elevated SA levels, a low level of spontaneous cell death, callose deposition, and enlarged cells in leaves. genetically maps on chr 4 between L23H3 and nga1139.; ABERRANT GROWTH AND DEATH 2 (AGD2); FUNCTIONS IN: transaminase activity, copper ion binding, L,L-diaminopimelate aminotransferase activity; INVOLVED IN: lysine biosynthetic process via diaminopimelate, systemic acquired resistance, salicylic acid mediated signaling pathway; LOCATED IN: chloroplast, chloroplast stroma; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: LL-diaminopimelate aminotransferase, plant-related (InterPro:IPR019942), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: AGD2-like defense response protein 1 (TAIR:AT2G13810.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1174.0) & (original description: no original description) kfl00340_0020_v1.1 0.8908411443896914 72 Kfl00028_0260 (at2g44580 : 266.0) zinc ion binding; CONTAINS InterPro DOMAIN/s: Sister chromatid cohesion protein DCC1 (InterPro:IPR019128); Has 214 Blast hits to 211 proteins in 110 species: Archae - 0; Bacteria - 0; Metazoa - 115; Fungi - 49; Plants - 36; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink). & (reliability: 532.0) & (original description: no original description) kfl00028_0260_v1.1 0.8906783568491627 69 Kfl00442_0050 (at5g19820 : 1219.0) embryo defective 2734 (emb2734); FUNCTIONS IN: lyase activity, binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: cell wall, phycobilisome; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: HEAT (InterPro:IPR000357), Armadillo-like helical (InterPro:IPR011989), HEAT, type 2 (InterPro:IPR021133), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT4G27640.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 2438.0) & (original description: no original description) kfl00442_0050_v1.1 0.8905212935113216 30 Kfl00567_0050 (at2g14050 : 705.0) minichromosome maintenance 9 (MCM9); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: DNA-dependent DNA replication initiation, DNA replication; LOCATED IN: cellular_component unknown; EXPRESSED IN: sperm cell, male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT1G44900.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q43704|mcm3_maize : 258.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1410.0) & (original description: no original description) kfl00567_0050_v1.1 0.8903184465749242 58 Kfl00165_0140 (at4g29910 : 184.0) Origin Recognition Complex subunit 5. Involved in the initiation of DNA replication. Interacts strongly with all ORC subunits.; origin recognition complex protein 5 (ORC5); CONTAINS InterPro DOMAIN/s: Origin recognition complex, subunit 5 (InterPro:IPR020796); Has 287 Blast hits to 283 proteins in 127 species: Archae - 0; Bacteria - 0; Metazoa - 140; Fungi - 92; Plants - 43; Viruses - 0; Other Eukaryotes - 12 (source: NCBI BLink). & (reliability: 368.0) & (original description: no original description) kfl00165_0140_v1.1 0.8898636326197067 68 Kfl00647_0040 (at3g48110 : 1020.0) glycine-tRNA ligase; EMBRYO-DEFECTIVE-DEVELOPMENT 1 (EDD1); FUNCTIONS IN: glycine-tRNA ligase activity; INVOLVED IN: regulation of embryonic development, glycyl-tRNA aminoacylation, embryo development ending in seed dormancy; LOCATED IN: mitochondrion, chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal (InterPro:IPR002311), Glycyl-tRNA synthetase, class II, heterodimeric (InterPro:IPR006194), Glycyl-tRNA synthetase, class IIc, beta subunit (InterPro:IPR015944), Glycyl-tRNA synthetase, class IIc, alpha subunit (InterPro:IPR002310); Has 11308 Blast hits to 11293 proteins in 1754 species: Archae - 4; Bacteria - 6864; Metazoa - 4; Fungi - 1; Plants - 40; Viruses - 0; Other Eukaryotes - 4395 (source: NCBI BLink). & (reliability: 2040.0) & (original description: no original description) kfl00647_0040_v1.1 0.8891999804349612 35 Kfl00307_0080 no hits & (original description: no original description) kfl00307_0080_v1.1 0.8891125021767262 33 Kfl00213_0030 (at1g04730 : 462.0) Necessary for sister chromatid cohesion. Acts in synergy with ETG1.; CHROMOSOME TRANSMISSION FIDELITY 18 (CTF18); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: sister chromatid cohesion; LOCATED IN: replication fork; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959); BEST Arabidopsis thaliana protein match is: replication factor C1 (TAIR:AT5G22010.1); Has 4018 Blast hits to 4006 proteins in 709 species: Archae - 400; Bacteria - 666; Metazoa - 673; Fungi - 766; Plants - 379; Viruses - 21; Other Eukaryotes - 1113 (source: NCBI BLink). & (reliability: 924.0) & (original description: no original description) kfl00213_0030_v1.1 0.888990764558819 83 Kfl00357_0110 (at5g52560 : 723.0) Encodes a protein with UTP:sugar 1-phosphate uridylyltransferase activity, which has been shown to use a wide range of substrates including glucose-1-P, galactose-1-P, xylose-1-P, arabinose-1-P and glucuronate-1-P. The enzyme was shown to require Mg2+ or Mn2+ for activity. Mutations in USP can lead to a complete loss of male fertility.; UDP-sugar pyrophosphorylase (USP); FUNCTIONS IN: in 6 functions; INVOLVED IN: in 6 processes; LOCATED IN: endomembrane system; EXPRESSED IN: 30 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: UTP--glucose-1-phosphate uridylyltransferase (InterPro:IPR002618); BEST Arabidopsis thaliana protein match is: N-acetylglucosamine-1-phosphate uridylyltransferase 1 (TAIR:AT1G31070.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1446.0) & (original description: no original description) kfl00357_0110_v1.1 0.8884411370684161 96 Kfl00608_0090 (at5g61460 : 571.0) Encodes SMC6B (STRUCTURAL MAINTENANCE OF CHROMOSOMES 6B), a component of the SMC5/6 complex. SMC5/6 complex promotes sister chromatid alignment and homologous recombination after DNA damage.; hypersensitive to MMS, irradiation and MMC (MIM); FUNCTIONS IN: ATP binding; INVOLVED IN: double-strand break repair, sister chromatid cohesion, chromosome segregation, response to X-ray, double-strand break repair via homologous recombination; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 6A (TAIR:AT5G07660.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1142.0) & (original description: no original description) kfl00608_0090_v1.1 0.8877044667391073 92 Kfl00062_0110 (at4g01160 : 99.8) BTB/POZ/Kelch-associated protein; CONTAINS InterPro DOMAIN/s: BTB/POZ (InterPro:IPR013069), BTB/Kelch-associated (InterPro:IPR011705), BTB/POZ fold (InterPro:IPR011333), Kelch related (InterPro:IPR013089), BTB/POZ-like (InterPro:IPR000210); BEST Arabidopsis thaliana protein match is: POZ/BTB containin G-protein 1 (TAIR:AT3G61600.2); Has 3481 Blast hits to 3463 proteins in 124 species: Archae - 0; Bacteria - 0; Metazoa - 3173; Fungi - 4; Plants - 136; Viruses - 49; Other Eukaryotes - 119 (source: NCBI BLink). & (reliability: 199.6) & (original description: no original description) kfl00062_0110_v1.1 0.8875631454217981 76 Kfl00053_0050 (p08437|h3_volca : 147.0) Histone H3 - Volvox carteri & (at5g10980 : 146.0) Histone superfamily protein; FUNCTIONS IN: DNA binding; INVOLVED IN: nucleosome assembly; LOCATED IN: nucleosome; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Histone H3 (InterPro:IPR000164), Histone-fold (InterPro:IPR009072), Histone core (InterPro:IPR007125); BEST Arabidopsis thaliana protein match is: Histone superfamily protein (TAIR:AT4G40030.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description) kfl00053_0050_v1.1 0.8873751923541361 47 Kfl00802_0070 (at3g47060 : 201.0) encodes an FtsH protease that is localized to the chloroplast; FTSH protease 7 (ftsh7); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity; INVOLVED IN: proteolysis, protein catabolic process; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: FTSH protease 9 (TAIR:AT5G58870.1); Has 41243 Blast hits to 38738 proteins in 3322 species: Archae - 1531; Bacteria - 17472; Metazoa - 4873; Fungi - 3612; Plants - 3353; Viruses - 32; Other Eukaryotes - 10370 (source: NCBI BLink). & (o82150|ftsh_tobac : 199.0) Cell division protease ftsH homolog, chloroplast precursor (EC 3.4.24.-) (DS9) - Nicotiana tabacum (Common tobacco) & (reliability: 402.0) & (original description: no original description) kfl00802_0070_v1.1 0.8863803765818473 39 Kfl00033_0310 (at2g16440 : 825.0) MINICHROMOSOME MAINTENANCE 4 (MCM4); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 4 (InterPro:IPR008047); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (q43704|mcm3_maize : 290.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1650.0) & (original description: no original description) kfl00033_0310_v1.1 0.8855769048804343 57 Kfl00376_0100 (q6es10|hat1_orysa : 137.0) Probable acetyltransferase type B catalytic subunit (EC 2.3.1.48) (HAT B) - Oryza sativa (Rice) & (at5g56740 : 130.0) Encodes an enzyme with histone acetyltransferase activity. Histone H4 is the primary substrate for the enzyme. Prior acetylation of lysine 12 of histone H4 reduces radioactive acetylation by HAG2. HAG2 acetylates histone H4 lysine 12.; histone acetyltransferase of the GNAT family 2 (HAG2); FUNCTIONS IN: histone acetyltransferase activity, H4 histone acetyltransferase activity; INVOLVED IN: histone acetylation, chromatin modification, chromatin silencing at telomere; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histone acetyltransferase type B, catalytic subunit (InterPro:IPR017380), GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), Acyl-CoA N-acyltransferase (InterPro:IPR016181), Histone acetyl transferase HAT1 N-terminal (InterPro:IPR019467); Has 368 Blast hits to 368 proteins in 193 species: Archae - 0; Bacteria - 0; Metazoa - 119; Fungi - 147; Plants - 50; Viruses - 0; Other Eukaryotes - 52 (source: NCBI BLink). & (reliability: 260.0) & (original description: no original description) kfl00376_0100_v1.1 0.8851939845528347 44 Kfl00030_0270 (at5g66750 : 640.0) Protein is similar to SWI2/SNF2 chromatin remodeling proteins. DDM1 is appears to act as a chromatin-remodeling ATPase involved in cytosine methylation in CG and non-CG contexts. Involved in gene silencing and maintenance of DNA methylation and histone methylation. Hypomethylation of many genomic regions occurs in ddm1 mutants, and can cause several phenotypic abnormalities, but some loci, such as BONSAI (At1g73177) can be hypermethylated in ddm1 mutants after several generations, leading to different phenotypes. DDM1 might be involved in establishing a heterochromain boundary. A line expressing an RNAi targeted against DDM1 shows some resistance to agrobacterium-mediated root transformation.; chromatin remodeling 1 (CHR1); FUNCTIONS IN: helicase activity, ATPase activity; INVOLVED IN: methylation-dependent chromatin silencing, DNA mediated transformation, transposition, RNA-mediated; LOCATED IN: nucleosome; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling factor17 (TAIR:AT5G18620.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (q7g8y3|isw2_orysa : 439.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 1280.0) & (original description: no original description) kfl00030_0270_v1.1 0.8841414641561453 68 Kfl00080_0200 (at1g70210 : 131.0) Encodes a D-type cyclin that physically interacts with CDC2A. Its expression is upregulated early during germination.; CYCLIN D1;1 (CYCD1;1); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: G1 phase of mitotic cell cycle, regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin D (InterPro:IPR015451), Cyclin-like (InterPro:IPR011028), Cyclin-related (InterPro:IPR013763), Cyclin, N-terminal (InterPro:IPR006671), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: Cyclin D2;1 (TAIR:AT2G22490.1); Has 3455 Blast hits to 3453 proteins in 343 species: Archae - 0; Bacteria - 0; Metazoa - 1586; Fungi - 382; Plants - 1073; Viruses - 13; Other Eukaryotes - 401 (source: NCBI BLink). & (reliability: 262.0) & (original description: no original description) kfl00080_0200_v1.1 0.8837674824870471 53 Kfl00043_0150 (at4g34570 : 494.0) Encodes a bifunctional dihydrofolate reductase - thymidylate synthase gene. This is unique in Arabidopsis and protozoa. Other organisms have independent genes for this function.; thymidylate synthase 2 (THY-2); CONTAINS InterPro DOMAIN/s: Thymidylate synthase, active site (InterPro:IPR020940), Dihydrofolate reductase domain (InterPro:IPR001796), Dihydrofolate reductase conserved site (InterPro:IPR017925), Bifunctional dihydrofolate reductase/thymidylate synthase (InterPro:IPR012262), Thymidylate synthase (InterPro:IPR000398); BEST Arabidopsis thaliana protein match is: thymidylate synthase 1 (TAIR:AT2G16370.1); Has 13567 Blast hits to 13544 proteins in 2627 species: Archae - 73; Bacteria - 8801; Metazoa - 517; Fungi - 428; Plants - 92; Viruses - 256; Other Eukaryotes - 3400 (source: NCBI BLink). & (o81395|drts_maize : 493.0) Bifunctional dihydrofolate reductase-thymidylate synthase (DHFR-TS) [Includes: Dihydrofolate reductase (EC 1.5.1.3); Thymidylate synthase (EC 2.1.1.45)] - Zea mays (Maize) & (reliability: 974.0) & (original description: no original description) kfl00043_0150_v1.1, kfl00043_0150_v1.1 0.880423192093627 92 Kfl00644_0020 (at4g14770 : 146.0) TESMIN/TSO1-like CXC 2 (TCX2); FUNCTIONS IN: sequence-specific DNA binding transcription factor activity; INVOLVED IN: regulation of transcription; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Tesmin/TSO1-like, CXC (InterPro:IPR005172); BEST Arabidopsis thaliana protein match is: Tesmin/TSO1-like CXC domain-containing protein (TAIR:AT3G22780.1); Has 1250 Blast hits to 741 proteins in 97 species: Archae - 0; Bacteria - 6; Metazoa - 464; Fungi - 8; Plants - 353; Viruses - 0; Other Eukaryotes - 419 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description) kfl00644_0020_v1.1 0.8798715888116448 97 Kfl00788_0010 (at5g46280 : 794.0) MINICHROMOSOME MAINTENANCE 3 (MCM3); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 3 (InterPro:IPR008046); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT4G02060.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (q43704|mcm3_maize : 643.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1588.0) & (original description: no original description) kfl00788_0010_v1.1 0.8784863186062631 65 Kfl00004_0160 (at3g54650 : 149.0) FBL17; FUNCTIONS IN: ubiquitin-protein ligase activity; INVOLVED IN: generative cell mitosis, seed development, embryo development, ubiquitin-dependent protein catabolic process, pollen development; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: F-box domain, cyclin-like (InterPro:IPR001810); Has 1738 Blast hits to 1195 proteins in 149 species: Archae - 0; Bacteria - 27; Metazoa - 733; Fungi - 89; Plants - 663; Viruses - 0; Other Eukaryotes - 226 (source: NCBI BLink). & (reliability: 298.0) & (original description: no original description) kfl00004_0160_v1.1 0.876033465193889 66 Kfl00422_0010 (at1g44900 : 989.0) Encodes MCM2 (MINICHROMOSOME MAINTENANCE 2), a protein essential to embryo development. Overexpression results in altered root meristem function.; MINICHROMOSOME MAINTENANCE 2 (MCM2); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: in 7 processes; LOCATED IN: nuclear chromatin; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 2 (InterPro:IPR008045), MCM protein 2, N-terminal (InterPro:IPR021092); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1). & (q43704|mcm3_maize : 308.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1978.0) & (original description: no original description) kfl00422_0010_v1.1 0.8753975710827536 49 Kfl00561_0040 no hits & (original description: no original description) kfl00561_0040_v1.1 0.8746003003862023 93 Kfl00144_0340 (at5g20990 : 432.0) Involved in molybdenum cofactor (Moco) biosynthesis, inserting Mo into Molybdopterin. sir loss-of-function mutants are resistant to sirtinol, a modulator of auxin signaling.; B73; CONTAINS InterPro DOMAIN/s: Molybdenum cofactor biosynthesis, conserved site (InterPro:IPR008284), Molybdenum cofactor synthesis (InterPro:IPR020817), MoeA, N-terminal and linker domain (InterPro:IPR005110), MoeA, C-terminal, domain IV (InterPro:IPR005111), Molybdopterin binding (InterPro:IPR001453); Has 13106 Blast hits to 12710 proteins in 1951 species: Archae - 648; Bacteria - 8919; Metazoa - 385; Fungi - 192; Plants - 74; Viruses - 0; Other Eukaryotes - 2888 (source: NCBI BLink). & (reliability: 864.0) & (original description: no original description) kfl00144_0340_v1.1 0.8720119100030223 96 Kfl00364_0060 no hits & (original description: no original description) kfl00364_0060_v1.1 0.8709713217666875 73 Kfl00153_0160 (at4g02070 : 834.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.; MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). & (q9xgc9|msh2_maize : 175.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 1668.0) & (original description: no original description) kfl00153_0160_v1.1 0.870713765917667 90 Kfl00184_0010 (at2g07690 : 812.0) Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.; MINICHROMOSOME MAINTENANCE 5 (MCM5); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin, nucleus, cytoplasm; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 5 (InterPro:IPR008048); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1). & (q43704|mcm3_maize : 306.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1624.0) & (original description: no original description) kfl00184_0010_v1.1 0.8701006696375269 60 Kfl00302_0030 (at1g67780 : 163.0) Zinc-finger domain of monoamine-oxidase A repressor R1 protein; CONTAINS InterPro DOMAIN/s: DDT domain superfamily (InterPro:IPR018501), DDT domain, subgroup (InterPro:IPR018500), Cell division cycle-associated protein (InterPro:IPR018866); BEST Arabidopsis thaliana protein match is: Zinc-finger domain of monoamine-oxidase A repressor R1 protein (TAIR:AT1G67270.1); Has 462 Blast hits to 453 proteins in 104 species: Archae - 0; Bacteria - 0; Metazoa - 139; Fungi - 73; Plants - 215; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink). & (reliability: 326.0) & (original description: no original description) kfl00302_0030_v1.1 0.8689894179654823 99 Kfl00349_0100 (at3g60830 : 373.0) Encodes an actin-related protein required for normal embryogenesis, plant architecture and floral organ abscission.; actin-related protein 7 (ARP7); CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000); BEST Arabidopsis thaliana protein match is: actin 3 (TAIR:AT3G53750.1); Has 12219 Blast hits to 11995 proteins in 2504 species: Archae - 0; Bacteria - 50; Metazoa - 5224; Fungi - 3189; Plants - 1407; Viruses - 2; Other Eukaryotes - 2347 (source: NCBI BLink). & (p30173|act13_soltu : 236.0) Actin-101 - Solanum tuberosum (Potato) & (reliability: 746.0) & (original description: no original description) kfl00349_0100_v1.1 0.8689663200377362 64 Kfl00336_0090 no hits & (original description: no original description) kfl00336_0090_v1.1 0.8685540062993851 65 Kfl00545_0070 (at3g02920 : 139.0) RPA32B; FUNCTIONS IN: nucleic acid binding; INVOLVED IN: biological_process unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Replication protein A, subunit RPA32 (InterPro:IPR014646), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Replication protein A, C-terminal (InterPro:IPR014892); BEST Arabidopsis thaliana protein match is: replicon protein A2 (TAIR:AT2G24490.2). & (reliability: 278.0) & (original description: no original description) kfl00545_0070_v1.1 0.868007346821469 96 Kfl00019_0370 (at2g45280 : 300.0) Encodes a protein similar to RAD51C involved in double stranded break repair via homologous recombination. Sensitive to DSB induced by Mitomycin C and gamma irradiation, interacts with Atxrcc3 in yeast two-hybrid assay. Required for female meiosis but not critical for mitosis under normal conditions.; RAS associated with diabetes protein 51C (RAD51C); CONTAINS InterPro DOMAIN/s: DNA recombination/repair protein RecA/RadB, ATP-binding domain (InterPro:IPR020588), DNA recombination and repair protein, RecA-like (InterPro:IPR016467), DNA recombination and repair protein Rad51, C-terminal (InterPro:IPR013632); BEST Arabidopsis thaliana protein match is: DNA repair (Rad51) family protein (TAIR:AT3G22880.1). & (p37384|dmc1_lillo : 110.0) Meiotic recombination protein DMC1 homolog - Lilium longiflorum (Trumpet lily) & (reliability: 600.0) & (original description: no original description) kfl00019_0370_v1.1 0.8662662082433658 67 Kfl00662_0040 (at1g16520 : 201.0) unknown protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT1G56080.1); Has 243 Blast hits to 234 proteins in 69 species: Archae - 2; Bacteria - 2; Metazoa - 61; Fungi - 9; Plants - 125; Viruses - 0; Other Eukaryotes - 44 (source: NCBI BLink). & (reliability: 402.0) & (original description: no original description) kfl00662_0040_v1.1 0.8652786879511037 69 Kfl00729_0030 (at5g40200 : 650.0) Encodes a putative DegP protease.; DegP protease 9 (DegP9); FUNCTIONS IN: serine-type peptidase activity, catalytic activity, serine-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: nucleolus, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Serine/cysteine peptidase, trypsin-like (InterPro:IPR009003), Serine endopeptidase DegP2 (InterPro:IPR015724), Peptidase S1C, HrtA/DegP2/Q/S (InterPro:IPR001940), Peptidase S1/S6, chymotrypsin/Hap (InterPro:IPR001254), PDZ/DHR/GLGF (InterPro:IPR001478); BEST Arabidopsis thaliana protein match is: DEGP protease 2 (TAIR:AT2G47940.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1300.0) & (original description: no original description) kfl00729_0030_v1.1 0.8651423890080666 69 Kfl00487_0010 no hits & (original description: no original description) kfl00487_0010_v1.1 0.8650549759630227 70 Kfl00173_0240 (q9zrj4|tba_chlvu : 789.0) Tubulin alpha chain - Chlorella vulgaris (Green alga) & (at4g14960 : 781.0) Encodes an alpha-tubulin isoform required for right handed helical growth.; TUA6; FUNCTIONS IN: protein binding, structural constituent of cytoskeleton; INVOLVED IN: response to salt stress, microtubule cytoskeleton organization, cellular response to gravity; LOCATED IN: in 8 components; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Alpha tubulin (InterPro:IPR002452), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: tubulin alpha-2 chain (TAIR:AT1G50010.1); Has 22664 Blast hits to 22566 proteins in 4681 species: Archae - 4; Bacteria - 25; Metazoa - 4398; Fungi - 13427; Plants - 1532; Viruses - 0; Other Eukaryotes - 3278 (source: NCBI BLink). & (reliability: 1562.0) & (original description: no original description) kfl00173_0240_v1.1 0.8640110933880747 72 Kfl00635_0040 (at4g18460 : 204.0) D-Tyr-tRNA(Tyr) deacylase family protein; FUNCTIONS IN: hydrolase activity, acting on ester bonds; INVOLVED IN: D-amino acid catabolic process; LOCATED IN: cytoplasm; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: D-tyrosyl-tRNA(Tyr) deacylase (InterPro:IPR003732); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 408.0) & (original description: no original description) kfl00635_0040_v1.1 0.863075349550668 74 Kfl00146_g3 no hits & (original description: no original description) kfl00146_g3_v1.1 0.8624205420018616 75 Kfl00032_0360 (at3g56490 : 174.0) Encodes a protein that has adenylylsulfate sulfohydrolase activity (E.C. 3.6.2.1) in vitro.; HIS triad family protein 3 (HIT3); FUNCTIONS IN: protein kinase C binding, adenylylsulfatase activity, zinc ion binding; INVOLVED IN: sulfur metabolic process, purine ribonucleotide metabolic process; LOCATED IN: peroxisome, plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Histidine triad-like motif (InterPro:IPR011146), Histidine triad, conserved site (InterPro:IPR019808), Histidine triad (HIT) protein (InterPro:IPR001310), Histidine triad motif (InterPro:IPR011151); BEST Arabidopsis thaliana protein match is: HISTIDINE TRIAD NUCLEOTIDE-BINDING 2 (TAIR:AT1G31160.1); Has 7957 Blast hits to 7956 proteins in 2592 species: Archae - 148; Bacteria - 4849; Metazoa - 343; Fungi - 139; Plants - 127; Viruses - 0; Other Eukaryotes - 2351 (source: NCBI BLink). & (p42856|zb14_maize : 174.0) 14 kDa zinc-binding protein (Protein kinase C inhibitor) (PKCI) - Zea mays (Maize) & (reliability: 348.0) & (original description: no original description) kfl00032_0360_v1.1 0.8624202471492024 76 Kfl00388_0030 (at1g26170 : 702.0) ARM repeat superfamily protein; FUNCTIONS IN: protein transporter activity, binding; INVOLVED IN: intracellular protein transport, protein import into nucleus, docking; LOCATED IN: nucleus, nuclear pore, cytoplasm; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Importin-beta, N-terminal (InterPro:IPR001494), Armadillo-like helical (InterPro:IPR011989), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: ARM repeat superfamily protein (TAIR:AT3G59020.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1404.0) & (original description: no original description) kfl00388_0030_v1.1 0.8611507653757835 78 Kfl00240_0070 (at5g55280 : 364.0) Encodes one of two FtsZ proteins, tubulin-like proteins, in Arabidopsis. It is involved in chloroplast division.; homolog of bacterial cytokinesis Z-ring protein FTSZ 1-1 (FTSZ1-1); FUNCTIONS IN: protein binding, structural molecule activity; INVOLVED IN: chloroplast fission, plastid fission; LOCATED IN: chloroplast stroma, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Cell division protein FtsZ, N-terminal (InterPro:IPR000158), Tubulin, conserved site (InterPro:IPR017975), Cell division protein FtsZ, conserved site (InterPro:IPR020805), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: Tubulin/FtsZ family protein (TAIR:AT3G52750.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 728.0) & (original description: no original description) kfl00240_0070_v1.1 0.860424897867027 79 Kfl00839_0060 (at3g05420 : 80.1) Acyl-CoA binding protein with high affinity for oleoyl-CoA. Expressed in all plant organs. Involved in fatty acid transport.; acyl-CoA binding protein 4 (ACBP4); FUNCTIONS IN: acyl-CoA binding; INVOLVED IN: lipid transport; LOCATED IN: cytosol, nucleus; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Galactose oxidase/kelch, beta-propeller (InterPro:IPR011043), Kelch repeat type 2 (InterPro:IPR011498), Acyl-CoA-binding protein, ACBP (InterPro:IPR000582), Kelch-type beta propeller (InterPro:IPR015915), FERM/acyl-CoA-binding protein, 3-helical bundle (InterPro:IPR014352); BEST Arabidopsis thaliana protein match is: acyl-CoA binding protein 5 (TAIR:AT5G27630.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 160.2) & (original description: no original description) kfl00839_0060_v1.1 0.8590358723854036 81 Kfl00040_0160 no hits & (original description: no original description) kfl00040_0160_v1.1 0.8575552919622371 85 Kfl00700_0040 (at1g76260 : 316.0) DWD (DDB1-binding WD40 protein) hypersensitive to ABA 2 (DWA2); CONTAINS InterPro DOMAIN/s: WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40 repeat (InterPro:IPR001680), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT1G20540.1); Has 7905 Blast hits to 6688 proteins in 412 species: Archae - 0; Bacteria - 764; Metazoa - 3555; Fungi - 1654; Plants - 1112; Viruses - 0; Other Eukaryotes - 820 (source: NCBI BLink). & (reliability: 632.0) & (original description: no original description) kfl00700_0040_v1.1 0.856988171395964 87 Kfl00768_0030 (at4g17610 : 561.0) tRNA/rRNA methyltransferase (SpoU) family protein; FUNCTIONS IN: RNA binding, RNA methyltransferase activity; INVOLVED IN: RNA processing; LOCATED IN: endomembrane system; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: tRNA/rRNA methyltransferase, SpoU (InterPro:IPR001537); Has 6630 Blast hits to 6614 proteins in 1865 species: Archae - 7; Bacteria - 4787; Metazoa - 103; Fungi - 50; Plants - 109; Viruses - 0; Other Eukaryotes - 1574 (source: NCBI BLink). & (reliability: 1122.0) & (original description: no original description) kfl00768_0030_v1.1 0.853865750930119 98 Kfl01000_0010 no hits & (original description: no original description) kfl01000_0010_v1.1 0.8535714905765351 90 Kfl00128_0270 no hits & (original description: no original description) kfl00128_0270_v1.1 0.8529207663728295 92 Kfl00169_0080 no hits & (original description: no original description) kfl00169_0080_v1.1 0.8513795272187465 94 Kfl00174_0030 no hits & (original description: no original description) kfl00174_0030_v1.1 0.8492535030904724 95 Kfl00046_0010 (at2g29680 : 209.0) Encodes cell division control protein 6 (CDC6).; cell division control 6 (CDC6); FUNCTIONS IN: ATP binding; INVOLVED IN: regulation of cell cycle, DNA replication; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), CDC6, C-terminal (InterPro:IPR015163), Cell division control, Cdc6 (InterPro:IPR016314); BEST Arabidopsis thaliana protein match is: Cell division control, Cdc6 (TAIR:AT1G07270.1); Has 1385 Blast hits to 1377 proteins in 339 species: Archae - 397; Bacteria - 0; Metazoa - 348; Fungi - 289; Plants - 116; Viruses - 0; Other Eukaryotes - 235 (source: NCBI BLink). & (reliability: 418.0) & (original description: no original description) kfl00046_0010_v1.1 0.8485864105521955 96 Kfl00042_0220 no hits & (original description: no original description) kfl00042_0220_v1.1 0.8483755490005718 97 Kfl00063_0300 no hits & (original description: no original description) kfl00063_0300_v1.1 0.8479035434805693 99