Sequence Description Alias PCC hrr evm.model.tig00001024.15 (at1g57820 : 133.0) Encodes a 645-amino acid methylcytosine-binding protein with a PHD domain, two RING finger domains, and an SRA domain that is involved in centromere heterochromatinization. This protein functions as an E3 ubiquitin ligase in vitro. The protein has been shown to bind to methylated cytosines of CG, CNG and CNN motifs via its SRA domain but has a preference for the former. It plays a role in the establishment/maintenance of chromatin structure during cell division and is localized in the nucleus. Plants over-expressing VIM1/ORTH2 show an inhibition in root growth and a delay in flowering. Both over-expression of GFP:ORTH2 and loss of ORTH2/VIM1 lead to decreased levels of DNA methylation. GFP:ORTH2 over-expressers also have increased levels of FWA transcripts.; VARIANT IN METHYLATION 1 (VIM1); CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), SRA-YDG (InterPro:IPR003105), Zinc finger, C3HC4 RING-type (InterPro:IPR018957), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: zinc finger (C3HC4-type RING finger) family protein (TAIR:AT1G57800.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 256.0) & (original description: no original description) 0.973770993581093 1 evm.model.tig00000551.12 (original description: no original description) 0.9631107536126431 11 evm.model.tig00020554.77 (at1g44900 : 595.0) Encodes MCM2 (MINICHROMOSOME MAINTENANCE 2), a protein essential to embryo development. Overexpression results in altered root meristem function.; MINICHROMOSOME MAINTENANCE 2 (MCM2); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: in 7 processes; LOCATED IN: nuclear chromatin; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 2 (InterPro:IPR008045), MCM protein 2, N-terminal (InterPro:IPR021092); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1). & (q43704|mcm3_maize : 207.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1190.0) & (original description: no original description) 0.9613021201118538 18 evm.model.tig00000889.12 no hits & (original description: no original description) 0.9578200306626209 8 evm.model.tig00020746.1 no hits & (original description: no original description) 0.9578179200147757 5 evm.model.tig00000615.19 no hits & (original description: no original description) 0.9548655331082608 13 evm.model.tig00021312.11 (p25011|ccnb1_soybn : 141.0) G2/mitotic-specific cyclin S13-6 (B-like cyclin) - Glycine max (Soybean) & (at4g35620 : 135.0) Cyclin B2;2 (CYCB2;2); FUNCTIONS IN: cyclin-dependent protein kinase regulator activity; INVOLVED IN: regulation of cell cycle; LOCATED IN: nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: Cyclin, C-terminal (InterPro:IPR004367), Cyclin-like (InterPro:IPR011028), Cyclin, N-terminal (InterPro:IPR006671), Cyclin, A/B/D/E (InterPro:IPR014400), Cyclin (InterPro:IPR006670); BEST Arabidopsis thaliana protein match is: Cyclin B2;1 (TAIR:AT2G17620.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 270.0) & (original description: no original description) 0.9525844782775619 22 evm.model.tig00021070.70 (at2g29680 : 205.0) Encodes cell division control protein 6 (CDC6).; cell division control 6 (CDC6); FUNCTIONS IN: ATP binding; INVOLVED IN: regulation of cell cycle, DNA replication; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), CDC6, C-terminal (InterPro:IPR015163), Cell division control, Cdc6 (InterPro:IPR016314); BEST Arabidopsis thaliana protein match is: Cell division control, Cdc6 (TAIR:AT1G07270.1); Has 1385 Blast hits to 1377 proteins in 339 species: Archae - 397; Bacteria - 0; Metazoa - 348; Fungi - 289; Plants - 116; Viruses - 0; Other Eukaryotes - 235 (source: NCBI BLink). & (reliability: 410.0) & (original description: no original description) 0.9511873809227017 19 evm.model.tig00000823.25 no hits & (original description: no original description) 0.9508343189285605 9 evm.model.tig00000237.42 (o48653|dpola_orysa : 568.0) DNA polymerase alpha catalytic subunit (EC 2.7.7.7) - Oryza sativa (Rice) & (at5g67100 : 554.0) Encodes the putative catalytic subunit of the DNA polymerase alpha. Interacts with genes involved in chromatin-mediated cellular memory. ICU2 genetically interacts with TERMINAL FLOWER2, the ortholog of HETEROCHROMATIN PROTEIN1 of animals and yeasts, and with the Polycomb group (PcG) gene CURLY LEAF. A number of regulatory genes were derepressed in the icu2-1 mutant, including genes associated with flowering time, floral meristem, and floral organ identity. Mutant has curled, involute leaves and causes early flowering.; INCURVATA2 (ICU2); FUNCTIONS IN: DNA-directed DNA polymerase activity; INVOLVED IN: negative regulation of flower development, leaf morphogenesis; LOCATED IN: nucleus; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134), Zinc finger, DNA-directed DNA polymerase, family B, alpha (InterPro:IPR015088), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved site (InterPro:IPR017964), DNA-directed DNA polymerase, family B (InterPro:IPR006172), DNA-directed DNA polymerase, family B, pol2 (InterPro:IPR004578); BEST Arabidopsis thaliana protein match is: DNA binding;nucleotide binding;nucleic acid binding;DNA-directed DNA polymerases;DNA-directed DNA polymerases (TAIR:AT5G63960.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 1108.0) & (original description: no original description) 0.9491757410096952 52 evm.model.tig00000144.188 (at5g66750 : 92.4) Protein is similar to SWI2/SNF2 chromatin remodeling proteins. DDM1 is appears to act as a chromatin-remodeling ATPase involved in cytosine methylation in CG and non-CG contexts. Involved in gene silencing and maintenance of DNA methylation and histone methylation. Hypomethylation of many genomic regions occurs in ddm1 mutants, and can cause several phenotypic abnormalities, but some loci, such as BONSAI (At1g73177) can be hypermethylated in ddm1 mutants after several generations, leading to different phenotypes. DDM1 might be involved in establishing a heterochromain boundary. A line expressing an RNAi targeted against DDM1 shows some resistance to agrobacterium-mediated root transformation.; chromatin remodeling 1 (CHR1); FUNCTIONS IN: helicase activity, ATPase activity; INVOLVED IN: methylation-dependent chromatin silencing, DNA mediated transformation, transposition, RNA-mediated; LOCATED IN: nucleosome; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: chromatin remodeling factor17 (TAIR:AT5G18620.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (q7g8y3|isw2_orysa : 80.9) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 184.8) & (original description: no original description) 0.9479367624346117 18 evm.model.tig00001333.30 (at1g04730 : 146.0) Necessary for sister chromatid cohesion. Acts in synergy with ETG1.; CHROMOSOME TRANSMISSION FIDELITY 18 (CTF18); FUNCTIONS IN: nucleoside-triphosphatase activity, ATPase activity, nucleotide binding, ATP binding; INVOLVED IN: sister chromatid cohesion; LOCATED IN: replication fork; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959); BEST Arabidopsis thaliana protein match is: replication factor C1 (TAIR:AT5G22010.1); Has 4018 Blast hits to 4006 proteins in 709 species: Archae - 400; Bacteria - 666; Metazoa - 673; Fungi - 766; Plants - 379; Viruses - 21; Other Eukaryotes - 1113 (source: NCBI BLink). & (reliability: 292.0) & (original description: no original description) 0.9463569278339721 42 evm.model.tig00000571.19 (at2g19330 : 115.0) Encodes PIRL6, a member of the Plant Intracellular Ras-group-related LRRs (Leucine rich repeat proteins). PIRLs are a distinct, plant-specific class of intracellular LRRs that likely mediate protein interactions, possibly in the context of signal transduction.; plant intracellular ras group-related LRR 6 (PIRL6); INVOLVED IN: biological_process unknown; LOCATED IN: chloroplast; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Leucine-rich repeat (InterPro:IPR001611); BEST Arabidopsis thaliana protein match is: plant intracellular ras group-related LRR 7 (TAIR:AT4G29880.1); Has 63918 Blast hits to 28732 proteins in 1043 species: Archae - 35; Bacteria - 6419; Metazoa - 27911; Fungi - 2141; Plants - 23572; Viruses - 21; Other Eukaryotes - 3819 (source: NCBI BLink). & (reliability: 208.0) & (original description: no original description) 0.9462472712745927 41 evm.model.tig00021352.40 (at5g46280 : 487.0) MINICHROMOSOME MAINTENANCE 3 (MCM3); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 3 (InterPro:IPR008046); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT4G02060.2); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (q43704|mcm3_maize : 436.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 974.0) & (original description: no original description) 0.9455103661689563 24 evm.model.tig00021348.83 no hits & (original description: no original description) 0.9432120382487658 19 evm.model.tig00021616.10 (at4g25540 : 375.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH3 heterodimers bound 'insertion-deletion' DNA with three nucleotides (+AAG) or one nucleotide (+T) looped out much better than they bound DNA with a base/base mispair (T/G).; homolog of DNA mismatch repair protein MSH3 (MSH3); CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695); BEST Arabidopsis thaliana protein match is: MUTS homolog 6 (TAIR:AT4G02070.2); Has 14547 Blast hits to 13713 proteins in 2703 species: Archae - 153; Bacteria - 9793; Metazoa - 705; Fungi - 864; Plants - 451; Viruses - 3; Other Eukaryotes - 2578 (source: NCBI BLink). & (q9xgc9|msh2_maize : 143.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 750.0) & (original description: no original description) 0.9411476888550167 73 evm.model.tig00000789.41 (at1g27880 : 173.0) DEAD/DEAH box RNA helicase family protein ; FUNCTIONS IN: helicase activity, nucleic acid binding, ATP-dependent helicase activity, ATP binding; INVOLVED IN: DNA recombination; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: DNA/RNA helicase, DEAD/DEAH box type, N-terminal (InterPro:IPR011545), DNA helicase, ATP-dependent, RecQ type (InterPro:IPR004589), DNA helicase, ATP-dependent, RecQ type, N-terminal (InterPro:IPR018329), DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site (InterPro:IPR002464), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: DEAD/DEAH box RNA helicase family protein (TAIR:AT4G35740.1); Has 41244 Blast hits to 39032 proteins in 2984 species: Archae - 762; Bacteria - 21282; Metazoa - 5401; Fungi - 4173; Plants - 3671; Viruses - 588; Other Eukaryotes - 5367 (source: NCBI BLink). & (reliability: 346.0) & (original description: no original description) 0.9403522472219948 33 evm.model.tig00000076.53 no hits & (original description: no original description) 0.940086636863117 18 evm.model.tig00000093.121 (q9xfg3|tbg_phypa : 270.0) Tubulin gamma chain (Gamma tubulin) - Physcomitrella patens (Moss) & (at5g05620 : 262.0) Paralog of TUBG1, required for centrosomal and noncentrosomal microtubule nucleation. Involved in specification of cell identity, such as stomatal patterning. Constitutively expressed throughout plant.; gamma-tubulin complex protein 2 (GCP2); FUNCTIONS IN: structural molecule activity, GTP binding, GTPase activity; INVOLVED IN: in 9 processes; LOCATED IN: in 6 components; CONTAINS InterPro DOMAIN/s: Gamma tubulin (InterPro:IPR002454), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: gamma-tubulin (TAIR:AT3G61650.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 524.0) & (original description: no original description) 0.940014130975507 19 evm.model.tig00000144.164 (at2g16440 : 634.0) MINICHROMOSOME MAINTENANCE 4 (MCM4); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA-dependent ATPase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 4 (InterPro:IPR008047); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (q43704|mcm3_maize : 294.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1268.0) & (original description: no original description) 0.9399704286765976 20 evm.model.tig00000241.188 no hits & (original description: no original description) 0.93990117431775 28 evm.model.tig00000113.108 no hits & (original description: no original description) 0.9391123103841374 22 evm.model.tig00020904.52 no hits & (original description: no original description) 0.9389497806212043 23 evm.model.tig00020556.22 no hits & (original description: no original description) 0.9371273402266724 24 evm.model.tig00020912.93 (at5g20930 : 230.0) Nuclear serine/threonine protein kinase that requires a coiled-coil region for oligomerization and catalytic activity. Required for leaf and flower development. Expression localized to the developing style by stage 13.; TOUSLED (TSL); FUNCTIONS IN: protein serine/threonine kinase activity, kinase activity; INVOLVED IN: protein amino acid phosphorylation; LOCATED IN: nucleus, chloroplast, cytoplasm; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Protein kinase, catalytic domain (InterPro:IPR000719), Serine/threonine-protein kinase domain (InterPro:IPR002290), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271); BEST Arabidopsis thaliana protein match is: ataurora3 (TAIR:AT2G45490.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 460.0) & (original description: no original description) 0.9364159587730649 27 evm.model.tig00022104.3 no hits & (original description: no original description) 0.9361895897021971 52 evm.model.tig00020930.25 no hits & (original description: no original description) 0.9361447362748764 27 evm.model.tig00021521.14 no hits & (original description: no original description) 0.9360712830731286 28 evm.model.tig00000711.46 (at2g27170 : 471.0) Encodes a member of the Arabidopsis cohesin complex that is essential for viability and sister chromatid alignment.; TITAN7 (TTN7); FUNCTIONS IN: ATP binding; INVOLVED IN: sister chromatid cohesion, chromosome segregation; LOCATED IN: cohesin complex, nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SMCs flexible hinge (InterPro:IPR010935), RecF/RecN/SMC protein, N-terminal (InterPro:IPR003395); BEST Arabidopsis thaliana protein match is: structural maintenance of chromosomes 2 (TAIR:AT5G62410.1); Has 158776 Blast hits to 77347 proteins in 3496 species: Archae - 2059; Bacteria - 28403; Metazoa - 67946; Fungi - 11949; Plants - 6773; Viruses - 706; Other Eukaryotes - 40940 (source: NCBI BLink). & (reliability: 942.0) & (original description: no original description) 0.9354616958477215 31 evm.model.tig00000980.12 no hits & (original description: no original description) 0.9352797034110915 36 evm.model.tig00021105.53 no hits & (original description: no original description) 0.9329365232749575 57 evm.model.tig00021432.30 no hits & (original description: no original description) 0.932836592469196 32 evm.model.tig00020918.5 (at5g44635 : 634.0) MINICHROMOSOME MAINTENANCE 6 (MCM6); FUNCTIONS IN: DNA-dependent ATPase activity, DNA binding, ATP binding; INVOLVED IN: cell proliferation, DNA-dependent DNA replication initiation, DNA unwinding involved in replication; LOCATED IN: nuclear chromatin; EXPRESSED IN: shoot apex; EXPRESSED DURING: IL.00 inflorescence just visible; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 6 (InterPro:IPR008049); BEST Arabidopsis thaliana protein match is: Minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT2G16440.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q43704|mcm3_maize : 243.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1268.0) & (original description: no original description) 0.9327415096590229 34 evm.model.tig00020537.3 no hits & (original description: no original description) 0.9327036026249977 34 evm.model.tig00021257.8 no hits & (original description: no original description) 0.9323250271122114 35 evm.model.tig00000545.42 no hits & (original description: no original description) 0.9321273027047156 47 evm.model.tig00000093.4 no hits & (original description: no original description) 0.9320221725676879 37 evm.model.tig00001224.8 (at3g18524 : 614.0) Encodes a DNA mismatch repair homolog of human MutS gene, MSH6. MSH2 is involved in maintaining genome stability and repressing recombination of mismatched heteroduplexes.There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2 has different binding specificity to different mismatches in combination with MSH3, MSH6, or MSH7.; MUTS homolog 2 (MSH2); FUNCTIONS IN: damaged DNA binding, protein binding, mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, negative regulation of reciprocal meiotic recombination; LOCATED IN: plasma membrane; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein, MSH2 (InterPro:IPR011184); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1); Has 13560 Blast hits to 13453 proteins in 2654 species: Archae - 128; Bacteria - 8942; Metazoa - 734; Fungi - 813; Plants - 457; Viruses - 3; Other Eukaryotes - 2483 (source: NCBI BLink). & (q9xgc9|msh2_maize : 591.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 1228.0) & (original description: no original description) 0.9319125179437728 76 evm.model.tig00000489.16 (at4g02070 : 188.0) encodes a DNA mismatch repair homolog of human MutS gene, MSH6. There are four MutS genes in Arabidopsis, MSH2, MSH3, MSH6, and MSH7, which all act as heterodimers and bind to 51-mer duplexes. MSH2*MSH6 bound the (+T) substrate strongly, (T/G) well, and (+AAG) no better than it did a (T/A) homoduplex.; MUTS homolog 6 (MSH6); FUNCTIONS IN: damaged DNA binding; INVOLVED IN: mismatch repair; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair protein Msh6 (InterPro:IPR017261), DNA mismatch repair protein MutS, clamp (InterPro:IPR007861), DNA mismatch repair protein MutS, connector (InterPro:IPR007860), DNA mismatch repair protein MutS, core (InterPro:IPR007696), DNA mismatch repair protein MutS-like, N-terminal (InterPro:IPR007695), DNA mismatch repair protein MutS, N-terminal (InterPro:IPR016151), DNA mismatch repair protein MutS, C-terminal (InterPro:IPR000432), DNA mismatch repair protein MutS-homologue MSH6 (InterPro:IPR015536), Tudor domain (InterPro:IPR002999); BEST Arabidopsis thaliana protein match is: homolog of DNA mismatch repair protein MSH3 (TAIR:AT4G25540.1). & (q9xgc9|msh2_maize : 111.0) DNA mismatch repair protein MSH2 (MUS1) - Zea mays (Maize) & (reliability: 376.0) & (original description: no original description) 0.9311283761902911 85 evm.model.tig00000042.241 no hits & (original description: no original description) 0.9310184318716624 40 evm.model.tig00000342.9 (at5g41880 : 330.0) POLA3; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer, DNA replication; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, small subunit (InterPro:IPR002755), DNA primase, small subunit, eukaryotic/archaeal (InterPro:IPR014052); Has 510 Blast hits to 504 proteins in 249 species: Archae - 95; Bacteria - 0; Metazoa - 124; Fungi - 138; Plants - 44; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink). & (reliability: 660.0) & (original description: no original description) 0.9300115760340871 57 evm.model.tig00000383.89 no hits & (original description: no original description) 0.9288098314065969 78 evm.model.tig00001254.1 no hits & (original description: no original description) 0.9285745862288456 43 evm.model.tig00020554.16 no hits & (original description: no original description) 0.9282333081091798 64 evm.model.tig00000903.42 no hits & (original description: no original description) 0.9274569325864799 45 evm.model.tig00000128.24 no hits & (original description: no original description) 0.9254737193913527 46 evm.model.tig00000737.5 (at4g12620 : 196.0) Origin Recognition Complex subunit 1b. Involved in the initiation of DNA replication. Regulated transcriptionally during cell cycle, peaking at G1/S-phase. Target of E2F/DF family of transcription factors. Interacts with ORC2 and ORC5. Highly expressed in proliferating cells. Expression levels are independent of light regime.; origin of replication complex 1B (ORC1B); CONTAINS InterPro DOMAIN/s: ATPase, AAA-type, core (InterPro:IPR003959), Zinc finger, PHD-type, conserved site (InterPro:IPR019786), Zinc finger, PHD-type (InterPro:IPR001965), Origin recognition complex, subunit 1 (InterPro:IPR020793), ATPase, AAA+ type, core (InterPro:IPR003593), Bromo adjacent homology (BAH) domain (InterPro:IPR001025), Zinc finger, FYVE/PHD-type (InterPro:IPR011011), Zinc finger, PHD-finger (InterPro:IPR019787); BEST Arabidopsis thaliana protein match is: origin recognition complex 1 (TAIR:AT4G14700.1); Has 5914 Blast hits to 5512 proteins in 383 species: Archae - 477; Bacteria - 4; Metazoa - 3209; Fungi - 806; Plants - 927; Viruses - 0; Other Eukaryotes - 491 (source: NCBI BLink). & (reliability: 392.0) & (original description: no original description) 0.9239038533805368 50 evm.model.tig00000157.40 no hits & (original description: no original description) 0.9192418501051478 53 evm.model.tig00000378.21 no hits & (original description: no original description) 0.9184343043838455 55 evm.model.tig00000865.64 no hits & (original description: no original description) 0.9183246947203063 56 evm.model.tig00020848.68 (at1g67320 : 337.0) DNA primase, large subunit family; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, large subunit, eukaryotic (InterPro:IPR016558), DNA primase, large subunit, eukaryotic/archaeal (InterPro:IPR007238). & (reliability: 674.0) & (original description: no original description) 0.9181132448619927 93 evm.model.tig00020563.82 no hits & (original description: no original description) 0.9179102391960147 58 evm.model.tig00000189.50 (at2g47980 : 176.0) Essential to the monopolar orientation of the kinetochores during meiosis.; sister-chromatid cohesion protein 3 (SCC3); FUNCTIONS IN: binding; INVOLVED IN: mitosis, attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation, meiotic sister chromatid cohesion, centromeric; LOCATED IN: chromosome, nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Armadillo-type fold (InterPro:IPR016024), STAG (InterPro:IPR013721), Stromalin conservative domain (InterPro:IPR020839); Has 568 Blast hits to 559 proteins in 184 species: Archae - 0; Bacteria - 2; Metazoa - 324; Fungi - 134; Plants - 52; Viruses - 0; Other Eukaryotes - 56 (source: NCBI BLink). & (reliability: 352.0) & (original description: no original description) 0.917904724644538 74 evm.model.tig00000880.20 no hits & (original description: no original description) 0.9172911338653087 60 evm.model.tig00000093.122 (q9xfg3|tbg_phypa : 385.0) Tubulin gamma chain (Gamma tubulin) - Physcomitrella patens (Moss) & (at5g05620 : 376.0) Paralog of TUBG1, required for centrosomal and noncentrosomal microtubule nucleation. Involved in specification of cell identity, such as stomatal patterning. Constitutively expressed throughout plant.; gamma-tubulin complex protein 2 (GCP2); FUNCTIONS IN: structural molecule activity, GTP binding, GTPase activity; INVOLVED IN: in 9 processes; LOCATED IN: in 6 components; CONTAINS InterPro DOMAIN/s: Gamma tubulin (InterPro:IPR002454), Tubulin (InterPro:IPR000217), Tubulin/FtsZ, GTPase domain (InterPro:IPR003008), Tubulin/FtsZ, N-terminal (InterPro:IPR019746), Tubulin/FtsZ, C-terminal (InterPro:IPR008280), Tubulin, conserved site (InterPro:IPR017975), Tubulin/FtsZ, 2-layer sandwich domain (InterPro:IPR018316); BEST Arabidopsis thaliana protein match is: gamma-tubulin (TAIR:AT3G61650.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 752.0) & (original description: no original description) 0.9169269991430188 65 evm.model.tig00001041.25 no hits & (original description: no original description) 0.9151801957419686 63 evm.model.tig00001466.2 no hits & (original description: no original description) 0.9144820740713493 63 evm.model.tig00001094.18 no hits & (original description: no original description) 0.9123558285260238 65 evm.model.tig00000037.21 (at4g29000 : 153.0) Tesmin/TSO1-like CXC domain-containing protein; CONTAINS InterPro DOMAIN/s: Tesmin/TSO1-like, CXC (InterPro:IPR005172); BEST Arabidopsis thaliana protein match is: Tesmin/TSO1-like CXC domain-containing protein (TAIR:AT2G20110.1); Has 1016 Blast hits to 666 proteins in 93 species: Archae - 0; Bacteria - 0; Metazoa - 285; Fungi - 4; Plants - 322; Viruses - 0; Other Eukaryotes - 405 (source: NCBI BLink). & (reliability: 306.0) & (original description: no original description) 0.9111359980056204 66 evm.model.tig00000691.35 (at3g06010 : 234.0) Encodes AtCHR12, a SNF2/Brahma-type chromatin-remodeling protein. AtCHR12 mediates temporary growth arrest in Arabidopsis upon perceiving environmental stress.; ATCHR12; FUNCTIONS IN: helicase activity, DNA binding, nucleic acid binding, ATP binding; INVOLVED IN: response to water deprivation, response to salt stress, response to heat; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: Homeotic gene regulator (TAIR:AT5G19310.1); Has 23556 Blast hits to 19403 proteins in 2220 species: Archae - 141; Bacteria - 6122; Metazoa - 5759; Fungi - 4503; Plants - 1859; Viruses - 268; Other Eukaryotes - 4904 (source: NCBI BLink). & (q7g8y3|isw2_orysa : 220.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 468.0) & (original description: no original description) 0.9110720684197954 67 evm.model.tig00001007.11 no hits & (original description: no original description) 0.9108843649027156 69 evm.model.tig00000093.55 no hits & (original description: no original description) 0.9095686838346071 72 evm.model.tig00000241.94 no hits & (original description: no original description) 0.9092635680939163 73 evm.model.tig00000808.15 (at5g58230 : 455.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 910.0) & (original description: no original description) 0.9068425000476809 74 evm.model.tig00000624.6 no hits & (original description: no original description) 0.9058086916330751 77 evm.model.tig00000227.41 (at1g77620 : 80.9) P-loop containing nucleoside triphosphate hydrolases superfamily protein; FUNCTIONS IN: nucleoside-triphosphatase activity, nucleotide binding; INVOLVED IN: DNA repair, cell cycle; LOCATED IN: nucleus; CONTAINS InterPro DOMAIN/s: Checkpoint protein Rad24 (InterPro:IPR004582), ATPase, AAA+ type, core (InterPro:IPR003593); BEST Arabidopsis thaliana protein match is: replication factor C1 (TAIR:AT5G22010.1); Has 1511 Blast hits to 1466 proteins in 328 species: Archae - 281; Bacteria - 0; Metazoa - 363; Fungi - 421; Plants - 133; Viruses - 9; Other Eukaryotes - 304 (source: NCBI BLink). & (reliability: 161.8) & (original description: no original description) 0.9048738401157023 100 evm.model.tig00001542.11 no hits & (original description: no original description) 0.9042313473260005 81 evm.model.tig00000388.53 no hits & (original description: no original description) 0.9038336647422083 82 evm.model.tig00000241.1 no hits & (original description: no original description) 0.9031021615917774 83 evm.model.tig00000789.46 no hits & (original description: no original description) 0.902899962810097 84 evm.model.tig00021035.25 no hits & (original description: no original description) 0.9004647042582122 87 evm.model.tig00000802.37 (at3g01660 : 152.0) S-adenosyl-L-methionine-dependent methyltransferases superfamily protein; FUNCTIONS IN: methyltransferase activity; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Methyltransferase type 11 (InterPro:IPR013216); BEST Arabidopsis thaliana protein match is: S-adenosyl-L-methionine-dependent methyltransferases superfamily protein (TAIR:AT4G29590.1); Has 1347 Blast hits to 1347 proteins in 403 species: Archae - 26; Bacteria - 759; Metazoa - 25; Fungi - 12; Plants - 94; Viruses - 0; Other Eukaryotes - 431 (source: NCBI BLink). & (reliability: 304.0) & (original description: no original description) 0.8995337705779299 88 evm.model.tig00020563.29 (at2g28840 : 85.5) XB3 ortholog 1 in Arabidopsis thaliana (XBAT31); FUNCTIONS IN: zinc ion binding; LOCATED IN: endomembrane system; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Ankyrin repeat-containing domain (InterPro:IPR020683), Ankyrin repeat (InterPro:IPR002110); BEST Arabidopsis thaliana protein match is: XB3 ortholog 3 in Arabidopsis thaliana (TAIR:AT5G07270.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 171.0) & (original description: no original description) 0.8989432015450147 89 evm.model.tig00000241.38 (at4g02060 : 657.0) Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.; PROLIFERA (PRL); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 7 (InterPro:IPR008050); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1). & (q43704|mcm3_maize : 291.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1314.0) & (original description: no original description) 0.8984287798399347 90 evm.model.tig00000970.31 (at1g08260 : 86.3) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 172.6) & (original description: no original description) 0.8977494750857099 96 evm.model.tig00000057.93 (at4g02460 : 221.0) Encodes a protein similar to PMS1 in yeast, a member of the family of eukaryotic MutL homologs. The protein appears to play a role in DNA mismatch repair and in the suppression of somatic homeologous recombination.; POSTMEIOTIC SEGREGATION 1 (PMS1); FUNCTIONS IN: mismatched DNA binding, ATP binding; INVOLVED IN: mismatch repair, fruit development, seed development, DNA recombination, pollen development; LOCATED IN: nucleus; EXPRESSED IN: 17 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: DNA mismatch repair, conserved site (InterPro:IPR014762), ATPase-like, ATP-binding domain (InterPro:IPR003594), DNA mismatch repair protein, C-terminal (InterPro:IPR013507), MutL, C-terminal, dimerisation (InterPro:IPR014790), DNA mismatch repair protein, N-terminal (InterPro:IPR014763), Ribosomal protein S5 domain 2-type fold (InterPro:IPR020568), DNA mismatch repair protein (InterPro:IPR002099), Post Meiotic Segregation 2 (InterPro:IPR015434), Ribosomal protein S5 domain 2-type fold, subgroup (InterPro:IPR014721); BEST Arabidopsis thaliana protein match is: MUTL-homologue 1 (TAIR:AT4G09140.1); Has 10471 Blast hits to 7086 proteins in 2377 species: Archae - 138; Bacteria - 7516; Metazoa - 568; Fungi - 666; Plants - 148; Viruses - 0; Other Eukaryotes - 1435 (source: NCBI BLink). & (reliability: 442.0) & (original description: no original description) 0.8971098332553786 92 evm.model.tig00021318.71 (at5g63200 : 92.8) tetratricopeptide repeat (TPR)-containing protein; FUNCTIONS IN: binding; INVOLVED IN: biological_process unknown; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G11540.1); Has 18351 Blast hits to 10064 proteins in 1197 species: Archae - 736; Bacteria - 8120; Metazoa - 2665; Fungi - 514; Plants - 588; Viruses - 0; Other Eukaryotes - 5728 (source: NCBI BLink). & (reliability: 185.6) & (original description: no original description) 0.8946820485923269 97