Sequence Description Alias PCC hrr evm.model.tig00020918.6 no hits & (original description: no original description) 0.9771711257045699 2 evm.model.tig00000980.11 no hits & (original description: no original description) 0.9749518779224038 2 evm.model.tig00000147.46 no hits & (original description: no original description) 0.9739887694241446 3 evm.model.tig00020553.141 (q43266|pcna_maize : 272.0) Proliferating cell nuclear antigen (PCNA) - Zea mays (Maize) & (at1g07370 : 265.0) Encodes putative proliferating cell nuclear antigen involved in cell cycle regulation.; proliferating cellular nuclear antigen 1 (PCNA1); CONTAINS InterPro DOMAIN/s: Proliferating cell nuclear antigen, PCNA (InterPro:IPR000730), Proliferating cell nuclear antigen, PCNA, C-terminal (InterPro:IPR022649), Proliferating cell nuclear antigen, PCNA, conserved site (InterPro:IPR022659), Proliferating cell nuclear antigen, PCNA, N-terminal (InterPro:IPR022648); BEST Arabidopsis thaliana protein match is: proliferating cell nuclear antigen 2 (TAIR:AT2G29570.1); Has 1857 Blast hits to 1845 proteins in 456 species: Archae - 391; Bacteria - 0; Metazoa - 315; Fungi - 169; Plants - 159; Viruses - 71; Other Eukaryotes - 752 (source: NCBI BLink). & (reliability: 530.0) & (original description: no original description) 0.9721605927899315 8 evm.model.tig00021319.67 (at2g29570 : 310.0) Functionally interacts with POLH to repair DNA damaged by UVB damage.; proliferating cell nuclear antigen 2 (PCNA2); FUNCTIONS IN: DNA binding, DNA polymerase processivity factor activity; INVOLVED IN: regulation of DNA replication, error-prone translesion synthesis; LOCATED IN: PCNA complex, nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proliferating cell nuclear antigen, PCNA (InterPro:IPR000730), Proliferating cell nuclear antigen, PCNA, C-terminal (InterPro:IPR022649), Proliferating cell nuclear antigen, PCNA, conserved site (InterPro:IPR022659), Proliferating cell nuclear antigen, PCNA, N-terminal (InterPro:IPR022648); BEST Arabidopsis thaliana protein match is: proliferating cellular nuclear antigen 1 (TAIR:AT1G07370.1); Has 1860 Blast hits to 1848 proteins in 457 species: Archae - 391; Bacteria - 0; Metazoa - 314; Fungi - 169; Plants - 159; Viruses - 73; Other Eukaryotes - 754 (source: NCBI BLink). & (o82134|pcna_pea : 310.0) Proliferating cell nuclear antigen - Pisum sativum (Garden pea) & (reliability: 620.0) & (original description: no original description) 0.9643981973652849 13 evm.model.tig00022075.57 (at5g06910 : 139.0) DnaJ homologue, contains J domain which is common in all known DnaJ proteins but missing G/F domain.; J-domain protein 6 (ATJ6); FUNCTIONS IN: unfolded protein binding, heat shock protein binding; INVOLVED IN: protein folding; LOCATED IN: nucleus; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Molecular chaperone, heat shock protein, Hsp40, DnaJ (InterPro:IPR015609), Heat shock protein DnaJ, N-terminal (InterPro:IPR001623), Heat shock protein DnaJ (InterPro:IPR003095); BEST Arabidopsis thaliana protein match is: Chaperone DnaJ-domain superfamily protein (TAIR:AT3G12170.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 278.0) & (original description: no original description) 0.962500884247778 6 evm.model.tig00000718.65 no hits & (original description: no original description) 0.9586626704094161 7 evm.model.tig00020902.41 (at5g02820 : 489.0) Involved in the patterning and shape of leaf trichomes. Encodes the DNA topoisomerase VI SPO11-3, involved in endoreduplication; ROOT HAIRLESS 2 (RHL2); CONTAINS InterPro DOMAIN/s: Spo11/DNA topoisomerase VI, subunit A, N-terminal (InterPro:IPR013049), DNA topoisomerase VI, subunit A (InterPro:IPR004085), Spo11/DNA topoisomerase VI, subunit A (InterPro:IPR002815); BEST Arabidopsis thaliana protein match is: Spo11/DNA topoisomerase VI, subunit A protein (TAIR:AT3G13170.1); Has 936 Blast hits to 932 proteins in 314 species: Archae - 223; Bacteria - 16; Metazoa - 170; Fungi - 119; Plants - 152; Viruses - 0; Other Eukaryotes - 256 (source: NCBI BLink). & (reliability: 978.0) & (original description: no original description) 0.9573288680930072 8 evm.model.tig00000704.48 (at5g27740 : 386.0) A locus involved in embryogenesis. Mutations in this locus result in embryo lethality.; EMBRYO DEFECTIVE 2775 (EMB2775); FUNCTIONS IN: nucleoside-triphosphatase activity, DNA binding, nucleotide binding, ATP binding; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), DNA polymerase III, clamp-loader complex, subunit E, C-terminal (InterPro:IPR019483), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921); BEST Arabidopsis thaliana protein match is: ATPase family associated with various cellular activities (AAA) (TAIR:AT1G21690.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 772.0) & (original description: no original description) 0.9560735363030287 9 evm.model.tig00000342.9 (at5g41880 : 330.0) POLA3; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer, DNA replication; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, small subunit (InterPro:IPR002755), DNA primase, small subunit, eukaryotic/archaeal (InterPro:IPR014052); Has 510 Blast hits to 504 proteins in 249 species: Archae - 95; Bacteria - 0; Metazoa - 124; Fungi - 138; Plants - 44; Viruses - 0; Other Eukaryotes - 109 (source: NCBI BLink). & (reliability: 660.0) & (original description: no original description) 0.9548274024863251 25 evm.model.tig00020848.68 (at1g67320 : 337.0) DNA primase, large subunit family; FUNCTIONS IN: DNA primase activity; INVOLVED IN: DNA replication, synthesis of RNA primer; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: DNA primase, large subunit, eukaryotic (InterPro:IPR016558), DNA primase, large subunit, eukaryotic/archaeal (InterPro:IPR007238). & (reliability: 674.0) & (original description: no original description) 0.9547683828802533 24 evm.model.tig00001214.13 (at5g26680 : 234.0) 5'-3' exonuclease family protein; FUNCTIONS IN: 5'-3' exonuclease activity, DNA binding, catalytic activity, nuclease activity; INVOLVED IN: DNA repair; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: XPG conserved site (InterPro:IPR019974), XPG N-terminal (InterPro:IPR006085), DNA repair protein (XPGC)/yeast Rad (InterPro:IPR006084), 5'-3' exonuclease, N-terminal (InterPro:IPR002421), 5'-3' exonuclease, C-terminal subdomain (InterPro:IPR020045), Helix-hairpin-helix motif, class 2 (InterPro:IPR008918), XPG/RAD2 endonuclease (InterPro:IPR006086); BEST Arabidopsis thaliana protein match is: 5'-3' exonuclease family protein (TAIR:AT1G29630.2); Has 3563 Blast hits to 3243 proteins in 839 species: Archae - 284; Bacteria - 855; Metazoa - 643; Fungi - 727; Plants - 266; Viruses - 42; Other Eukaryotes - 746 (source: NCBI BLink). & (q9sxq6|fen1a_orysa : 231.0) Flap endonuclease 1a (EC 3.1.-.-) (OsFEN-1a) - Oryza sativa (Rice) & (reliability: 468.0) & (original description: no original description) 0.9541916462612267 12 evm.model.tig00020780.19 no hits & (original description: no original description) 0.9501354095249048 19 evm.model.tig00020684.26 (at3g02920 : 90.9) RPA32B; FUNCTIONS IN: nucleic acid binding; INVOLVED IN: biological_process unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Replication protein A, subunit RPA32 (InterPro:IPR014646), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Replication protein A, C-terminal (InterPro:IPR014892); BEST Arabidopsis thaliana protein match is: replicon protein A2 (TAIR:AT2G24490.2). & (reliability: 181.8) & (original description: no original description) 0.9492162374153389 38 evm.model.tig00020531.58 (at2g23530 : 96.7) Zinc-finger domain of monoamine-oxidase A repressor R1; CONTAINS InterPro DOMAIN/s: Cell division cycle-associated protein (InterPro:IPR018866); BEST Arabidopsis thaliana protein match is: Zinc-finger domain of monoamine-oxidase A repressor R1 (TAIR:AT4G37110.1); Has 512 Blast hits to 506 proteins in 112 species: Archae - 0; Bacteria - 4; Metazoa - 144; Fungi - 73; Plants - 256; Viruses - 0; Other Eukaryotes - 35 (source: NCBI BLink). & (reliability: 193.4) & (original description: no original description) 0.9483682866789526 15 evm.model.tig00000789.47 no hits & (original description: no original description) 0.9464246928624716 16 evm.model.tig00020943.41 (at2g25100 : 214.0) Polynucleotidyl transferase, ribonuclease H-like superfamily protein; FUNCTIONS IN: ribonuclease H activity, RNA binding, catalytic activity, nucleic acid binding; INVOLVED IN: RNA metabolic process; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ribonuclease H2, subunit A (InterPro:IPR004649), Ribonuclease HII/HIII (InterPro:IPR001352), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337); Has 6305 Blast hits to 6298 proteins in 2456 species: Archae - 256; Bacteria - 4469; Metazoa - 152; Fungi - 137; Plants - 56; Viruses - 3; Other Eukaryotes - 1232 (source: NCBI BLink). & (reliability: 428.0) & (original description: no original description) 0.9444747567314323 27 evm.model.tig00000241.178 (q9lre5|dpod2_orysa : 317.0) DNA polymerase delta small subunit (EC 2.7.7.7) - Oryza sativa (Rice) & (at2g42120 : 311.0) DNA polymerase delta small subunit (POLD2); FUNCTIONS IN: DNA binding, DNA-directed DNA polymerase activity; INVOLVED IN: DNA replication; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase alpha/epsilon, subunit B (InterPro:IPR007185); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 622.0) & (original description: no original description) 0.9372301657843533 49 evm.model.tig00021319.28 no hits & (original description: no original description) 0.934873654043377 19 evm.model.tig00000254.120 no hits & (original description: no original description) 0.9330957909219918 52 evm.model.tig00000857.21 no hits & (original description: no original description) 0.9319584404508807 21 evm.model.tig00000691.32 no hits & (original description: no original description) 0.9312312284562794 22 evm.model.tig00020903.47 no hits & (original description: no original description) 0.929656337761626 23 evm.model.tig00020553.189 no hits & (original description: no original description) 0.9291368637892934 24 evm.model.tig00001049.34 no hits & (original description: no original description) 0.9289690950018652 45 evm.model.tig00000383.42 (at3g27060 : 431.0) Encodes one of the 3 ribonucleotide reductase (RNR) small subunit genes. TSO2 transcription occurs predominantly at the S-phase of the cell cycle and its expression pattern is consistent with its role in dNDP biosynthesis during DNA replication in actively dividing cells. Critical for cell cycle progression, DNA damage repair and plant development.; TSO MEANING 'UGLY' IN CHINESE 2 (TSO2); FUNCTIONS IN: oxidoreductase activity, transition metal ion binding, ribonucleoside-diphosphate reductase activity; INVOLVED IN: in 6 processes; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ribonucleotide reductase-related (InterPro:IPR012348), Ribonucleotide reductase (InterPro:IPR000358), Ferritin/ribonucleotide reductase-like (InterPro:IPR009078); BEST Arabidopsis thaliana protein match is: ribonucleotide reductase 2A (TAIR:AT3G23580.1); Has 9355 Blast hits to 9350 proteins in 2299 species: Archae - 34; Bacteria - 4270; Metazoa - 263; Fungi - 240; Plants - 185; Viruses - 729; Other Eukaryotes - 3634 (source: NCBI BLink). & (p49730|rir2_tobac : 427.0) Ribonucleoside-diphosphate reductase small chain (EC 1.17.4.1) (Ribonucleotide reductase small subunit) (Ribonucleoside-diphosphate reductase R2 subunit) - Nicotiana tabacum (Common tobacco) & (reliability: 862.0) & (original description: no original description) 0.9288231370696651 30 evm.model.tig00000042.30 (at1g63160 : 390.0) replication factor C 2 (RFC2); FUNCTIONS IN: in 6 functions; INVOLVED IN: DNA replication; LOCATED IN: DNA replication factor C complex; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), Replication factor C (InterPro:IPR013748), DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal (InterPro:IPR008921); BEST Arabidopsis thaliana protein match is: ATPase family associated with various cellular activities (AAA) (TAIR:AT1G21690.1); Has 17520 Blast hits to 17472 proteins in 2840 species: Archae - 620; Bacteria - 9832; Metazoa - 859; Fungi - 958; Plants - 372; Viruses - 89; Other Eukaryotes - 4790 (source: NCBI BLink). & (reliability: 780.0) & (original description: no original description) 0.9286817083327001 27 evm.model.tig00000970.31 (at1g08260 : 86.3) Similar to POL2A, DNA polymerase epsilon catalytic subunit. Essential for Arabidopsis growth. Null homozygotes are embryo lethal, partial loss of function alleles show embryo patterning defects such as root pole displacement. Delayed progression through cell cycle results in embryos with smaller numbers of larger cells.; TILTED 1 (TIL1); FUNCTIONS IN: DNA-directed DNA polymerase activity, DNA binding, nucleotide binding, zinc ion binding, nucleic acid binding; INVOLVED IN: positive regulation of S phase of mitotic cell cycle, negative regulation of long-day photoperiodism, flowering, embryo development ending in seed dormancy; LOCATED IN: apoplast, epsilon DNA polymerase complex; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: DNA polymerase, family B (InterPro:IPR022762), DNA-directed DNA polymerase, family B, exonuclease domain (InterPro:IPR006133), Domain of unknown function DUF1744 (InterPro:IPR013697), Polynucleotidyl transferase, ribonuclease H fold (InterPro:IPR012337), DNA-directed DNA polymerase, family B, conserved region (InterPro:IPR006134); BEST Arabidopsis thaliana protein match is: DNA polymerase epsilon catalytic subunit (TAIR:AT2G27120.1); Has 2011 Blast hits to 1700 proteins in 652 species: Archae - 331; Bacteria - 603; Metazoa - 305; Fungi - 291; Plants - 83; Viruses - 58; Other Eukaryotes - 340 (source: NCBI BLink). & (reliability: 172.6) & (original description: no original description) 0.9262893752816359 33 evm.model.tig00001302.6 (at3g25100 : 125.0) Required for normal meiosis, may act in the last round of DNA replication prior to meiosis, sequence similar to yeast CDC45; cell division cycle 45 (CDC45); CONTAINS InterPro DOMAIN/s: CDC45-like protein (InterPro:IPR003874); Has 1810 Blast hits to 1657 proteins in 252 species: Archae - 0; Bacteria - 25; Metazoa - 666; Fungi - 449; Plants - 176; Viruses - 35; Other Eukaryotes - 459 (source: NCBI BLink). & (reliability: 250.0) & (original description: no original description) 0.9250294620225871 32 evm.model.tig00021105.53 no hits & (original description: no original description) 0.9232379417342279 83 evm.model.tig00000405.51 no hits & (original description: no original description) 0.922962264137318 35 evm.model.tig00021234.25 no hits & (original description: no original description) 0.9229273621902149 32 evm.model.tig00020554.132 no hits & (original description: no original description) 0.9216338828373634 53 evm.model.tig00021127.4 (at3g48150 : 429.0) anaphase-promoting complex or cyclosome subunit; anaphase-promoting complex subunit 8 (APC8); FUNCTIONS IN: binding; INVOLVED IN: cell cycle, regulation of mitotic metaphase/anaphase transition; LOCATED IN: anaphase-promoting complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Cdc23 (InterPro:IPR007192), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G16320.1); Has 14789 Blast hits to 8989 proteins in 1164 species: Archae - 889; Bacteria - 6197; Metazoa - 2204; Fungi - 825; Plants - 603; Viruses - 0; Other Eukaryotes - 4071 (source: NCBI BLink). & (reliability: 858.0) & (original description: no original description) 0.9207075579811229 34 evm.model.tig00000076.93 (o04235|ssrp1_vicfa : 250.0) FACT complex subunit SSRP1 (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) - Vicia faba (Broad bean) & (at3g28730 : 239.0) encodes a component of the FAcilitates Chromatin Transcription (FACT) complex, SSRP1. Along with STP16 binds to the promoter of FLC.; high mobility group (HMG); CONTAINS InterPro DOMAIN/s: Structure-specific recognition protein (InterPro:IPR000969), High mobility group, superfamily (InterPro:IPR009071), High mobility group, HMG1/HMG2 (InterPro:IPR000910); BEST Arabidopsis thaliana protein match is: high mobility group B1 (TAIR:AT3G51880.2); Has 8066 Blast hits to 7188 proteins in 653 species: Archae - 0; Bacteria - 14; Metazoa - 5623; Fungi - 822; Plants - 671; Viruses - 15; Other Eukaryotes - 921 (source: NCBI BLink). & (reliability: 478.0) & (original description: no original description) 0.9202070871775598 35 evm.model.tig00000241.91 no hits & (original description: no original description) 0.9178843120994173 49 evm.model.tig00020848.65 no hits & (original description: no original description) 0.9164900490499713 38 evm.model.tig00021254.39 (at5g59440 : 149.0) Encodes thymidylate kinase which exists in two isoforms in plants. The longer variant of 263 amino acids with a N-terminal extension that is required for localization to the mitochondrion. The second isoform of 224 residues is localized to the cytoplasm and nucleoplasm. Peak of expression occurs during G1/S phase transition.; ZEUS1 (ZEU1); FUNCTIONS IN: thymidylate kinase activity, ATP binding; INVOLVED IN: dTDP biosynthetic process; LOCATED IN: nucleoplasm, mitochondrion, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Thymidylate kinase (InterPro:IPR018094), Thymidylate kinase-like (InterPro:IPR000062), Thymidylate kinase, conserved site (InterPro:IPR018095); Has 5505 Blast hits to 5503 proteins in 2206 species: Archae - 247; Bacteria - 3933; Metazoa - 204; Fungi - 151; Plants - 114; Viruses - 143; Other Eukaryotes - 713 (source: NCBI BLink). & (reliability: 298.0) & (original description: no original description) 0.9164791111753486 76 evm.model.tig00000388.21 (at3g18630 : 220.0) Encodes a uracil-DNA glycosylase (UDG) involved in a base excision DNA repair pathway in mitochondria.; uracil dna glycosylase (UNG); FUNCTIONS IN: uracil DNA N-glycosylase activity; INVOLVED IN: DNA repair, base-excision repair; LOCATED IN: mitochondrion; EXPRESSED IN: 15 plant structures; EXPRESSED DURING: 8 growth stages; CONTAINS InterPro DOMAIN/s: Uracil-DNA glycosylase (InterPro:IPR002043), Uracil-DNA glycosylase-like (InterPro:IPR005122); BEST Arabidopsis thaliana protein match is: unknown protein (TAIR:AT2G10550.1); Has 5606 Blast hits to 5606 proteins in 2219 species: Archae - 2; Bacteria - 4117; Metazoa - 124; Fungi - 141; Plants - 47; Viruses - 234; Other Eukaryotes - 941 (source: NCBI BLink). & (reliability: 440.0) & (original description: no original description) 0.9158978839782727 69 evm.model.tig00021582.33 (at4g37110 : 102.0) Zinc-finger domain of monoamine-oxidase A repressor R1; FUNCTIONS IN: zinc ion binding; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type (InterPro:IPR001841), Cell division cycle-associated protein (InterPro:IPR018866); BEST Arabidopsis thaliana protein match is: Zinc-finger domain of monoamine-oxidase A repressor R1 (TAIR:AT2G23530.1); Has 452 Blast hits to 447 proteins in 93 species: Archae - 0; Bacteria - 0; Metazoa - 137; Fungi - 54; Plants - 229; Viruses - 0; Other Eukaryotes - 32 (source: NCBI BLink). & (reliability: 204.0) & (original description: no original description) 0.9144506619452658 42 evm.model.tig00000157.40 no hits & (original description: no original description) 0.9132921480006716 55 evm.model.tig00000042.241 no hits & (original description: no original description) 0.9118840151416132 54 evm.model.tig00020610.31 no hits & (original description: no original description) 0.9104676491155341 45 evm.model.tig00020904.52 no hits & (original description: no original description) 0.9089080472729304 70 evm.model.tig00000157.111 (at5g46210 : 334.0) Arabidopsis CULLIN4 (CUL4) forms an E3 ubiquitin ligase with the CDD complex and a common catalytic subunit RBX1 in mediating light control of development. This CUL4-based E3 ligase is essential for the repression of photomorphogenesis. The partial loss of CUL4 function resulted in a constitutive photomorphogenic phenotype with respect to morphogenesis and light-regulated gene expression. CUL4 exhibits a synergistic genetic interaction with COP10 and DET1.; cullin4 (CUL4); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin protein, neddylation domain (InterPro:IPR019559), Cullin, N-terminal (InterPro:IPR001373), Cullin, conserved site (InterPro:IPR016157), Cullin repeat-like-containing domain (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: cullin 3B (TAIR:AT1G69670.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 668.0) & (original description: no original description) 0.9077425459509801 48 evm.model.tig00000829.8 no hits & (original description: no original description) 0.9074900643142515 49 evm.model.tig00000889.32 no hits & (original description: no original description) 0.9059325271325541 53 evm.model.tig00021720.13 (p05434|catr_chlre : 256.0) Caltractin (Centrin) (20 kDa calcium-binding protein) - Chlamydomonas reinhardtii & (at3g50360 : 203.0) centrin2 (CEN2); FUNCTIONS IN: calcium ion binding; INVOLVED IN: biological_process unknown; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: EF-Hand 1, calcium-binding site (InterPro:IPR018247), EF-HAND 2 (InterPro:IPR018249), EF-hand-like domain (InterPro:IPR011992), Calcium-binding EF-hand (InterPro:IPR002048), EF-hand (InterPro:IPR018248); BEST Arabidopsis thaliana protein match is: centrin 2 (TAIR:AT4G37010.2); Has 32825 Blast hits to 20606 proteins in 1695 species: Archae - 1; Bacteria - 190; Metazoa - 13563; Fungi - 7187; Plants - 7027; Viruses - 2; Other Eukaryotes - 4855 (source: NCBI BLink). & (reliability: 406.0) & (original description: no original description) 0.9052395077689727 75 evm.model.tig00000350.25 no hits & (original description: no original description) 0.9038726371352125 55 evm.model.tig00021319.35 no hits & (original description: no original description) 0.9023420459930219 56 evm.model.tig00001094.18 no hits & (original description: no original description) 0.902037203711247 57 evm.model.tig00000042.4 (at4g16420 : 167.0) Transcriptional co-activator. Essential for the developmental switch from cell proliferation to cell differentiation in response to variations in auxin and cytokinin concentrations.; homolog of yeast ADA2 2B (ADA2B); CONTAINS InterPro DOMAIN/s: SANT, eukarya (InterPro:IPR017884), SANT, DNA-binding (InterPro:IPR001005), Transcriptional adaptor 2 (InterPro:IPR016827), Myb, DNA-binding (InterPro:IPR014778), Homeodomain-like (InterPro:IPR009057), SWIRM (InterPro:IPR007526), Zinc finger, ZZ-type (InterPro:IPR000433), Homeodomain-related (InterPro:IPR012287); BEST Arabidopsis thaliana protein match is: homolog of yeast ADA2 2A (TAIR:AT3G07740.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 334.0) & (original description: no original description) 0.9017147582378312 59 evm.model.tig00001024.23 no hits & (original description: no original description) 0.9013190341091536 60 evm.model.tig00020614.100 no hits & (original description: no original description) 0.9005612829781308 61 evm.model.tig00000754.21 no hits & (original description: no original description) 0.8992055887462894 62 evm.model.tig00020537.31 no hits & (original description: no original description) 0.8985481050154573 64 evm.model.tig00000241.113 (p51173|apea_dicdi : 224.0) DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (Class II apurinic/apyrimidinic(AP)-endonuclease) - Dictyostelium discoideum (Slime mold) & (at2g41460 : 222.0) apurinic endonuclease-redox protein. It functions as an apurinic/apyrimidinic class II endonuclease, and is involved in DNA repair.; apurinic endonuclease-redox protein (ARP); CONTAINS InterPro DOMAIN/s: DNA-binding SAP (InterPro:IPR003034), AP endonuclease, family 1, binding site (InterPro:IPR020847), Exodeoxyribonuclease III xth (InterPro:IPR004808), Endonuclease/exonuclease/phosphatase (InterPro:IPR005135); BEST Arabidopsis thaliana protein match is: C2 calcium/lipid-binding endonuclease/exonuclease/phosphatase (TAIR:AT3G60950.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 444.0) & (original description: no original description) 0.8940108932957184 70 evm.model.tig00020563.160 (at5g24630 : 114.0) This gene is predicted to encode a protein that forms part of the topoisomerase VI complex. BIN4 is a nuclear-localized protein that can bind DNA. bin4 mutants are brassinolide-insensitive dwarves with severely reduced cell size in leaves, roots, and hypocotyls. Proper development of root hairs and trichomes is also disrupted in bin4 mutants and they have elevated levels of double strand breaks in their cotyledon cells.; brassinosteroid-insensitive4 (BIN4); FUNCTIONS IN: double-stranded DNA binding; INVOLVED IN: in 7 processes; LOCATED IN: DNA topoisomerase complex (ATP-hydrolyzing), nucleus; EXPRESSED IN: cotyledon vascular system, cotyledon, root tip, leaf trichome, leaf; Has 3628 Blast hits to 2405 proteins in 320 species: Archae - 6; Bacteria - 1196; Metazoa - 1107; Fungi - 390; Plants - 165; Viruses - 17; Other Eukaryotes - 747 (source: NCBI BLink). & (reliability: 228.0) & (original description: no original description) 0.89372424145058 71 evm.model.tig00000241.145 no hits & (original description: no original description) 0.8937154008928164 72 evm.model.tig00020746.1 no hits & (original description: no original description) 0.893153931983354 77 evm.model.tig00000241.38 (at4g02060 : 657.0) Member of the minichromosome maintenance complex, involved in DNA replication initiation. Abundant in proliferating and endocycling tissues. Localized in the nucleus during G1, S and G2 phases of the cell cycle, and are released into the cytoplasmic compartment during mitosis. Binds chromatin.; PROLIFERA (PRL); CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid-binding, OB-fold (InterPro:IPR012340), ATPase, AAA+ type, core (InterPro:IPR003593), DNA-dependent ATPase MCM (InterPro:IPR001208), DNA-dependent ATPase MCM, conserved site (InterPro:IPR018525), MCM protein 7 (InterPro:IPR008050); BEST Arabidopsis thaliana protein match is: minichromosome maintenance (MCM2/3/5) family protein (TAIR:AT5G44635.1). & (q43704|mcm3_maize : 291.0) DNA replication licensing factor MCM3 homolog (Replication origin activator) (ROA protein) (Fragment) - Zea mays (Maize) & (reliability: 1314.0) & (original description: no original description) 0.8925835687239027 74 evm.model.tig00001336.8 no hits & (original description: no original description) 0.8925166215277373 88 evm.model.tig00000254.61 no hits & (original description: no original description) 0.8908469058493858 76 evm.model.tig00001041.20 no hits & (original description: no original description) 0.8900963584527823 98 evm.model.tig00000692.3 no hits & (original description: no original description) 0.8891495213245394 78 evm.model.tig00000823.18 (at4g19130 : 136.0) Replication factor-A protein 1-related; FUNCTIONS IN: DNA binding, zinc ion binding, nucleic acid binding; INVOLVED IN: DNA replication; LOCATED IN: nucleus; EXPRESSED IN: sperm cell, flower; EXPRESSED DURING: petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Replication factor-a protein 1 Rpa1 (InterPro:IPR004591), Nucleic acid-binding, OB-fold (InterPro:IPR012340), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), Nucleic acid binding, OB-fold, tRNA/helicase-type (InterPro:IPR004365), Replication factor A, C-terminal (InterPro:IPR013955), Zinc finger, CCHC-type (InterPro:IPR001878), Replication factor-A protein 1, N-terminal (InterPro:IPR007199); BEST Arabidopsis thaliana protein match is: Replication factor-A protein 1-related (TAIR:AT5G45400.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 272.0) & (original description: no original description) 0.8883179733347628 79 evm.model.tig00000808.15 (at5g58230 : 455.0) Encodes a WD-40 repeat containing protein that functions in chromatin assembly as part of the CAF1 and FIE complex. Mutants exhibit parthenogenetic development that includes proliferation of unfertilized endosperm and embryos. In heterozygous plants 50% of embryos abort. Of the aborted embryos the early aborted class are homozygous and the later aborting lass are heterozygotes in which the defective allele is maternally transmitted. Other phenotypes include defects in ovule morphogenesis and organ initiation,as well as increased levels of heterochromatic DNA. MSI1 is needed for the transition to flowering. In Arabidopsis, the three CAF-1 subunits are encoded by FAS1, FAS2 and, most likely, MSI1, respectively. Mutations in FAS1 or FAS2 lead to increased frequency of homologous recombination and T-DNA integration in Arabidopsis. In the ovule, the MSI1 transcripts are accumulated at their highest level before fertilization and gradually decrease after fertilization. MSI is biallelically expressed, the paternall allele is expressed in the endosperm and embryo and is not imprinted. MSI1 forms a complex with RBR1 that is required for activation of the imprinted genes FIS2 and FWA. This activation is mediated by MSI1/RBR1 mediated repression of MET1.; MULTICOPY SUPRESSOR OF IRA1 (MSI1); FUNCTIONS IN: protein binding; INVOLVED IN: in 13 processes; LOCATED IN: nucleus, chloroplast, chromatin remodeling complex, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Histone-binding protein RBBP4 (InterPro:IPR022052), WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin family protein / WD-40 repeat family protein (TAIR:AT2G16780.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 910.0) & (original description: no original description) 0.8862337034908331 81 evm.model.tig00000789.14 no hits & (original description: no original description) 0.8862321840708677 81 evm.model.tig00001299.14 no hits & (original description: no original description) 0.8850717888269946 82 evm.model.tig00021491.7 (at1g13180 : 246.0) Mutant has defect in trichome cell expansion and actin organization resulting in a distorted trichome phenotype.; DISTORTED TRICHOMES 1 (DIS1); FUNCTIONS IN: actin binding, structural constituent of cytoskeleton, ATP binding; INVOLVED IN: actin filament organization, multidimensional cell growth, cell morphogenesis, trichome morphogenesis; LOCATED IN: Arp2/3 protein complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Actin/actin-like (InterPro:IPR004000), Actin-related protein 3 (InterPro:IPR015623); BEST Arabidopsis thaliana protein match is: Actin-like ATPase superfamily protein (TAIR:AT2G42100.1); Has 12406 Blast hits to 12242 proteins in 2483 species: Archae - 6; Bacteria - 5; Metazoa - 5339; Fungi - 3178; Plants - 1454; Viruses - 2; Other Eukaryotes - 2422 (source: NCBI BLink). & (p17299|act3_orysa : 169.0) Actin-3 - Oryza sativa (Rice) & (reliability: 492.0) & (original description: no original description) 0.8828363342548885 83 evm.model.tig00001278.6 (at4g26840 : 80.1) Encodes a small ubiquitin-like modifier (SUMO) polypeptide that becomes covalently attached to various intracellular protein targets, much like ubiquitination, leading to post-translational modification of those targets.; small ubiquitin-like modifier 1 (SUMO1); CONTAINS InterPro DOMAIN/s: Ubiquitin (InterPro:IPR000626), Ubiquitin supergroup (InterPro:IPR019955); BEST Arabidopsis thaliana protein match is: small ubiquitin-like modifier 2 (TAIR:AT5G55160.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink). & (reliability: 160.2) & (original description: no original description) 0.8823276255748772 85 evm.model.tig00000983.25 no hits & (original description: no original description) 0.8817411896945773 87 evm.model.tig00001033.16 no hits & (original description: no original description) 0.8801793473954072 91 evm.model.tig00000310.43 no hits & (original description: no original description) 0.877278982011104 94 evm.model.tig00001374.10 (p15451|cyc_chlre : 106.0) Cytochrome c - Chlamydomonas reinhardtii & (at1g22840 : 95.5) Encodes cytochrome c. Contains two site II (TGGGCC/T) elements, which interact with a TCP-domain transcription factor, and a downstream internal telomeric repeat, and are required for expression of the Cytc-1 gene. Promoter directs preferential expression in root and shoot meristems and in anthers.; CYTOCHROME C-1 (CYTC-1); FUNCTIONS IN: electron carrier activity, copper ion binding; INVOLVED IN: cell proliferation; LOCATED IN: mitochondrion, plasma membrane; EXPRESSED IN: 31 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome c, class IA/ IB (InterPro:IPR002327), Cytochrome c, class I (InterPro:IPR003088), Cytochrome c domain (InterPro:IPR009056); BEST Arabidopsis thaliana protein match is: cytochrome c-2 (TAIR:AT4G10040.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 191.0) & (original description: no original description) 0.8754169616108031 98 evm.model.tig00001333.26 no hits & (original description: no original description) 0.8743324170709253 99 evm.model.tig00020554.14 no hits & (original description: no original description) 0.8729989632821773 100