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Description : (at3g10800 : 125.0) Encodes bZIP28, a putative membrane-tethered transcriptional factor. Up-regulated in response to heat; a bZIP28 null mutant has a heat-sensitive phenotype. bZIP28 has a similar domain structure to the mammalian ATF6 protein involved in the unfolded protein response (UPR), and shares a bZIP domain, transmembrane domain, and a canonical S1P cleavage site. The bZIP28 seems to be glycosylated in vivo. bZIP28 does not appear to be transcriptionally up-regulated by UPR-inducing tunicamycin (TM) treatment. But, the expression level of three UPR-related genes is reduced in TM-treated zip28 mutants relative to wild type seedlings. And several UPR genes are transcriptionally upregulated when an N-terminal portion of the bZIP28 protein is expressed using the 35S promoter. A myc:bZIP28 fusion protein appears to be cleaved, likely at a canonical S2 cleavage site, following a TM treatment or a DTT stress-inducing treatment, but not a salt treatment. A portion of the mGFP:bZIP28 protein present in root cells appears to translocate from the cytoplasm and ER to the nucleus following TM treatment.; BZIP28; CONTAINS InterPro DOMAIN/s: Basic-leucine zipper (bZIP) transcription factor (InterPro:IPR004827), bZIP transcription factor, bZIP-1 (InterPro:IPR011616); BEST Arabidopsis thaliana protein match is: Basic-leucine zipper (bZIP) transcription factor family protein (TAIR:AT2G40950.1); Has 1906 Blast hits to 1391 proteins in 215 species: Archae - 0; Bacteria - 248; Metazoa - 700; Fungi - 222; Plants - 463; Viruses - 4; Other Eukaryotes - 269 (source: NCBI BLink). & (p14233|tga1b_tobac : 86.7) TGACG-sequence-specific DNA-binding protein TGA-1B (TGA1b) (HSBF) (Fragment) - Nicotiana tabacum (Common tobacco) & (reliability: 250.0) & (original description: no original description)
Condition specificity: 7 h after dark (SPM: 0.37, entropy: 2.28, tau: 0.24)