Description : (at2g38440 : 131.0) Encodes a subunit of the WAVE complex. The WAVE complex is required for activation of ARP2/3 complex which functions in actin microfilament nucleation and branching. Mutations cause defects in both the actin and microtubule cytoskeletons that result in aberrant epidermal cell expansion. itb1 mutants showed irregularities in trichome branch positioning and expansion. The SHD domain of this protein binds to BRK1 and overexpression of the SHD domain results in a dominant negative phenotype.; SCAR homolog 2 (SCAR2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: in 6 processes; LOCATED IN: SCAR complex, plasma membrane, cytoplasm; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Actin-binding WH2 (InterPro:IPR003124); BEST Arabidopsis thaliana protein match is: SCAR family protein 4 (TAIR:AT5G01730.1); Has 5162 Blast hits to 2275 proteins in 363 species: Archae - 24; Bacteria - 2785; Metazoa - 880; Fungi - 591; Plants - 224; Viruses - 0; Other Eukaryotes - 658 (source: NCBI BLink). & (q5qna6|scrl2_orysa : 114.0) SCAR-like protein 2 - Oryza sativa (Rice) & (reliability: 262.0) & (original description: no original description)
Condition specificity: 1 h after dark (SPM: 0.33, entropy: 2.46, tau: 0.14)