Description : (at1g26830 : 1167.0) Cullin, putative, similar to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with other components of E3 ligase complex suggesting it functions in RUB-modification. Forms complexes with BTB domain proteins forming a novel class of E3-based ubiquitin protein-ligase complexes. Mutant is early flowering and has a reduced sensitivity to far-red light. cul3a/cul3b homozygous/heterozygous plants are embryo lethal.; cullin 3 (CUL3); CONTAINS InterPro DOMAIN/s: Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin protein, neddylation domain (InterPro:IPR019559), Cullin, N-terminal (InterPro:IPR001373), Cullin repeat-like-containing domain (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: cullin 3B (TAIR:AT1G69670.1); Has 2310 Blast hits to 2269 proteins in 235 species: Archae - 0; Bacteria - 9; Metazoa - 1034; Fungi - 455; Plants - 372; Viruses - 0; Other Eukaryotes - 440 (source: NCBI BLink). & (reliability: 2334.0) & (original description: no original description)
Condition specificity: 6 h after dark (SPM: 0.47, entropy: 1.92, tau: 0.16)