Description : (at1g17220 : 268.0) Encodes a chloroplast localized protein with similarity to translation initiation factor 2. Can complement loss of INFB in E.coli suggesting FUG1 does function as a translation initiation factor in vivo. Identified as a suppressor of the leaf variegation mutant var2-6. Suppression is only seen in hypomorphs as complete loss of function alleles are embryo lethal.; fu-gaeri1 (FUG1); FUNCTIONS IN: translation initiation factor activity; INVOLVED IN: translational initiation; LOCATED IN: chloroplast, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Translation initiation factor IF-2, N-terminal (InterPro:IPR006847), Small GTP-binding protein (InterPro:IPR005225), Translation elongation factor EFTu/EF1A, domain 2 (InterPro:IPR004161), Translation initiation factor 2 related (InterPro:IPR015760), Initiation factor 2 (InterPro:IPR000178), Protein synthesis factor, GTP-binding (InterPro:IPR000795), Translation elongation/initiation factor/Ribosomal, beta-barrel (InterPro:IPR009000); BEST Arabidopsis thaliana protein match is: Translation initiation factor 2, small GTP-binding protein (TAIR:AT4G11160.1); Has 64472 Blast hits to 64325 proteins in 4737 species: Archae - 1215; Bacteria - 42273; Metazoa - 2198; Fungi - 2344; Plants - 1110; Viruses - 4; Other Eukaryotes - 15328 (source: NCBI BLink). & (p57997|if2c_phavu : 252.0) Translation initiation factor IF-2, chloroplast precursor (PvIF2cp) - Phaseolus vulgaris (Kidney bean) (French bean) & (reliability: 536.0) & (original description: no original description)
Condition specificity: 6 h after dark (SPM: 0.44, entropy: 1.58, tau: 0.08)