Mp1g25400.1

Description : 2-isopropylmalate synthase

Gene families : OG_42_0001355 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001355_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Marchantia polymorpha: Mp1g25400.1
Cluster	HCAA Clusters: Cluster_11

Target	Alias	Description	ECC score	Gene Family Method
Seita.7G317500.1	No alias	2-isopropylmalate synthase *(IPMS) & EC_2.3 acyltransferase	0.03	Orthogroups_2024-Update
Sopen06g018460	No alias	HMGL-like	0.03	Orthogroups_2024-Update
evm.model.tig00020780.44	No alias	no hits & (original description: no original description)	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	IEA	16Dec
MF	GO:0003852	2-isopropylmalate synthase activity	IEA	16Dec
BP	GO:0006082	organic acid metabolic process	None	Extended
BP	GO:0006520	cellular amino acid metabolic process	None	Extended
BP	GO:0006551	leucine metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0008652	cellular amino acid biosynthetic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009081	branched-chain amino acid metabolic process	None	Extended
BP	GO:0009082	branched-chain amino acid biosynthetic process	None	Extended
BP	GO:0009098	leucine biosynthetic process	IEA	16Dec
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016053	organic acid biosynthetic process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016746	transferase activity, transferring acyl groups	None	Extended
BP	GO:0019752	carboxylic acid metabolic process	None	Extended
BP	GO:0043436	oxoacid metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044281	small molecule metabolic process	None	Extended
BP	GO:0044283	small molecule biosynthetic process	None	Extended
BP	GO:0046394	carboxylic acid biosynthetic process	None	Extended
MF	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:1901605	alpha-amino acid metabolic process	None	Extended
BP	GO:1901607	alpha-amino acid biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003724	RNA helicase activity	IEP	Predicted GO
MF	GO:0003916	DNA topoisomerase activity	IEP	Predicted GO
MF	GO:0004470	malic enzyme activity	IEP	Predicted GO
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Predicted GO
MF	GO:0005244	voltage-gated ion channel activity	IEP	Predicted GO
MF	GO:0005247	voltage-gated chloride channel activity	IEP	Predicted GO
MF	GO:0005253	anion channel activity	IEP	Predicted GO
MF	GO:0005254	chloride channel activity	IEP	Predicted GO
MF	GO:0005515	protein binding	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005643	nuclear pore	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
CC	GO:0005759	mitochondrial matrix	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006265	DNA topological change	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006473	protein acetylation	IEP	Predicted GO
BP	GO:0006474	N-terminal protein amino acid acetylation	IEP	Predicted GO
BP	GO:0006821	chloride transport	IEP	Predicted GO
MF	GO:0008308	voltage-gated anion channel activity	IEP	Predicted GO
MF	GO:0015108	chloride transmembrane transporter activity	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016615	malate dehydrogenase activity	IEP	Predicted GO
MF	GO:0017056	structural constituent of nuclear pore	IEP	Predicted GO
BP	GO:0017196	N-terminal peptidyl-methionine acetylation	IEP	Predicted GO
BP	GO:0018193	peptidyl-amino acid modification	IEP	Predicted GO
BP	GO:0018206	peptidyl-methionine modification	IEP	Predicted GO
MF	GO:0022832	voltage-gated channel activity	IEP	Predicted GO
MF	GO:0022836	gated channel activity	IEP	Predicted GO
MF	GO:0022839	ion gated channel activity	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
CC	GO:0031248	protein acetyltransferase complex	IEP	Predicted GO
BP	GO:0031365	N-terminal protein amino acid modification	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0031414	N-terminal protein acetyltransferase complex	IEP	Predicted GO
CC	GO:0031417	NatC complex	IEP	Predicted GO
CC	GO:0031974	membrane-enclosed lumen	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043233	organelle lumen	IEP	Predicted GO
BP	GO:0043543	protein acylation	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
CC	GO:0070013	intracellular organelle lumen	IEP	Predicted GO
BP	GO:0071103	DNA conformation change	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
CC	GO:1902493	acetyltransferase complex	IEP	Predicted GO
CC	GO:1990904	ribonucleoprotein complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013709	2-isopropylmalate_synth_dimer	478	622
IPR000891	PYR_CT	99	378

External Links

No external refs found!

Mp1g25400.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation