Mp4g02270.1

Description : mitochondrial NAD-dependent malic enzyme

Gene families : OG_42_0002866 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002866_tree

Sequence : coding (download), protein (download)

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Marchantia polymorpha: Mp4g02270.1
Cluster	HCAA Clusters: Cluster_76

Target	Alias	Description	ECC score	Gene Family Method
176472	No alias	NAD-dependent malic enzyme 1	0.02	Orthogroups_2024-Update
Brara.C02902.1	No alias	mitochondrial NAD-dependent malic enzyme & EC_1.1...	0.04	Orthogroups_2024-Update
Brara.I00034.1	No alias	mitochondrial NAD-dependent malic enzyme & EC_1.1...	0.02	Orthogroups_2024-Update
HORVU1Hr1G045720.1	No alias	mitochondrial NAD-dependent malic enzyme & EC_1.1...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004470	malic enzyme activity	None	Extended
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEA	16Dec
MF	GO:0005488	binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0016491	oxidoreductase activity	None	Extended
MF	GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	None	Extended
MF	GO:0016615	malate dehydrogenase activity	None	Extended
MF	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0048037	cofactor binding	None	Extended
MF	GO:0050662	coenzyme binding	None	Extended
MF	GO:0051287	NAD binding	IEA	16Dec
BP	GO:0055114	oxidation-reduction process	IEA	16Dec
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Predicted GO
MF	GO:0003872	6-phosphofructokinase activity	IEP	Predicted GO
MF	GO:0003879	ATP phosphoribosyltransferase activity	IEP	Predicted GO
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Predicted GO
MF	GO:0004190	aspartic-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity	IEP	Predicted GO
CC	GO:0005737	cytoplasm	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0006073	cellular glucan metabolic process	IEP	Predicted GO
BP	GO:0006082	organic acid metabolic process	IEP	Predicted GO
BP	GO:0006163	purine nucleotide metabolic process	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006541	glutamine metabolic process	IEP	Predicted GO
BP	GO:0006542	glutamine biosynthetic process	IEP	Predicted GO
BP	GO:0006547	histidine metabolic process	IEP	Predicted GO
BP	GO:0006555	methionine metabolic process	IEP	Predicted GO
BP	GO:0006612	protein targeting to membrane	IEP	Predicted GO
BP	GO:0006613	cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	IEP	Predicted GO
BP	GO:0006665	sphingolipid metabolic process	IEP	Predicted GO
BP	GO:0006672	ceramide metabolic process	IEP	Predicted GO
BP	GO:0006886	intracellular protein transport	IEP	Predicted GO
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Predicted GO
BP	GO:0008104	protein localization	IEP	Predicted GO
MF	GO:0008236	serine-type peptidase activity	IEP	Predicted GO
MF	GO:0008312	7S RNA binding	IEP	Predicted GO
MF	GO:0008443	phosphofructokinase activity	IEP	Predicted GO
BP	GO:0008652	cellular amino acid biosynthetic process	IEP	Predicted GO
BP	GO:0009066	aspartate family amino acid metabolic process	IEP	Predicted GO
BP	GO:0009123	nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009126	purine nucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009141	nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009144	purine nucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009150	purine ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0009161	ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009167	purine ribonucleoside monophosphate metabolic process	IEP	Predicted GO
BP	GO:0009199	ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009205	purine ribonucleoside triphosphate metabolic process	IEP	Predicted GO
BP	GO:0009259	ribonucleotide metabolic process	IEP	Predicted GO
BP	GO:0015031	protein transport	IEP	Predicted GO
BP	GO:0015833	peptide transport	IEP	Predicted GO
BP	GO:0016053	organic acid biosynthetic process	IEP	Predicted GO
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	IEP	Predicted GO
MF	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016757	transferase activity, transferring glycosyl groups	IEP	Predicted GO
MF	GO:0016759	cellulose synthase activity	IEP	Predicted GO
MF	GO:0016760	cellulose synthase (UDP-forming) activity	IEP	Predicted GO
MF	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	IEP	Predicted GO
MF	GO:0016840	carbon-nitrogen lyase activity	IEP	Predicted GO
MF	GO:0016843	amine-lyase activity	IEP	Predicted GO
MF	GO:0016844	strictosidine synthase activity	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0017144	drug metabolic process	IEP	Predicted GO
MF	GO:0017171	serine hydrolase activity	IEP	Predicted GO
MF	GO:0019200	carbohydrate kinase activity	IEP	Predicted GO
BP	GO:0019693	ribose phosphate metabolic process	IEP	Predicted GO
BP	GO:0019752	carboxylic acid metabolic process	IEP	Predicted GO
CC	GO:0019867	outer membrane	IEP	Predicted GO
BP	GO:0022406	membrane docking	IEP	Predicted GO
BP	GO:0030243	cellulose metabolic process	IEP	Predicted GO
BP	GO:0030244	cellulose biosynthetic process	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
BP	GO:0033036	macromolecule localization	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
BP	GO:0042886	amide transport	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043436	oxoacid metabolic process	IEP	Predicted GO
BP	GO:0044042	glucan metabolic process	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0044281	small molecule metabolic process	IEP	Predicted GO
BP	GO:0044283	small molecule biosynthetic process	IEP	Predicted GO
BP	GO:0045184	establishment of protein localization	IEP	Predicted GO
BP	GO:0046034	ATP metabolic process	IEP	Predicted GO
BP	GO:0046394	carboxylic acid biosynthetic process	IEP	Predicted GO
MF	GO:0046527	glucosyltransferase activity	IEP	Predicted GO
BP	GO:0046907	intracellular transport	IEP	Predicted GO
BP	GO:0048278	vesicle docking	IEP	Predicted GO
CC	GO:0048500	signal recognition particle	IEP	Predicted GO
MF	GO:0051536	iron-sulfur cluster binding	IEP	Predicted GO
MF	GO:0051539	4 iron, 4 sulfur cluster binding	IEP	Predicted GO
MF	GO:0051540	metal cluster binding	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
BP	GO:0051641	cellular localization	IEP	Predicted GO
BP	GO:0051649	establishment of localization in cell	IEP	Predicted GO
BP	GO:0052803	imidazole-containing compound metabolic process	IEP	Predicted GO
MF	GO:0070001	aspartic-type peptidase activity	IEP	Predicted GO
BP	GO:0071702	organic substance transport	IEP	Predicted GO
BP	GO:0072521	purine-containing compound metabolic process	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
BP	GO:0140029	exocytic process	IEP	Predicted GO
BP	GO:0140056	organelle localization by membrane tethering	IEP	Predicted GO
BP	GO:1901135	carbohydrate derivative metabolic process	IEP	Predicted GO
BP	GO:1901605	alpha-amino acid metabolic process	IEP	Predicted GO
BP	GO:1901607	alpha-amino acid biosynthetic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR012302	Malic_NAD-bd	311	578
IPR012301	Malic_N_dom	121	301

External Links

No external refs found!

Mp4g02270.1

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation