At5g55310

Description : DNA topoisomerase 1 beta [Source:UniProtKB/Swiss-Prot;Acc:Q9FJ79]

Gene families : OG_42_0004287 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004287_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Arabidopsis release: At5g55310
Cluster	HCCA clusters: Cluster_166

Target	Alias	Description	ECC score	Gene Family Method
Glyma.12G013600	No alias	DNA topoisomerase I alpha	0.03	Orthogroups_2024-Update
Kfl00061_0370	kfl00061_0370_v1.1	(at5g55310 : 669.0) Encodes one of two Arabidopsis...	0.02	Orthogroups_2024-Update
LOC_Os08g05840	No alias	DNA topoisomerase 1, putative, expressed	0.02	Orthogroups_2024-Update
MA_120434g0010	No alias	(at5g55300 : 828.0) Encodes a type-I DNA topoisomerase...	0.04	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003916	DNA topoisomerase activity	None	Extended
MF	GO:0003917	DNA topoisomerase type I activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006265	DNA topological change	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006996	organelle organization	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016853	isomerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051276	chromosome organization	None	Extended
BP	GO:0071103	DNA conformation change	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000139	Golgi membrane	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
CC	GO:0000428	DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0000724	double-strand break repair via homologous recombination	IEP	Predicted GO
BP	GO:0000725	recombinational repair	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0003989	acetyl-CoA carboxylase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005665	RNA polymerase II, core complex	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006310	DNA recombination	IEP	Predicted GO
BP	GO:0006366	transcription by RNA polymerase II	IEP	Predicted GO
BP	GO:0006906	vesicle fusion	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008237	metallopeptidase activity	IEP	Predicted GO
MF	GO:0008565	protein transporter activity	IEP	Predicted GO
CC	GO:0009317	acetyl-CoA carboxylase complex	IEP	Predicted GO
BP	GO:0016050	vesicle organization	IEP	Predicted GO
MF	GO:0016421	CoA carboxylase activity	IEP	Predicted GO
BP	GO:0016458	gene silencing	IEP	Predicted GO
MF	GO:0016885	ligase activity, forming carbon-carbon bonds	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0030880	RNA polymerase complex	IEP	Predicted GO
BP	GO:0031047	gene silencing by RNA	IEP	Predicted GO
MF	GO:0031625	ubiquitin protein ligase binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
MF	GO:0044389	ubiquitin-like protein ligase binding	IEP	Predicted GO
BP	GO:0048280	vesicle fusion with Golgi apparatus	IEP	Predicted GO
BP	GO:0048284	organelle fusion	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
CC	GO:0055029	nuclear DNA-directed RNA polymerase complex	IEP	Predicted GO
BP	GO:0061024	membrane organization	IEP	Predicted GO
BP	GO:0061025	membrane fusion	IEP	Predicted GO
CC	GO:0061695	transferase complex, transferring phosphorus-containing groups	IEP	Predicted GO
BP	GO:0090174	organelle membrane fusion	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013500	TopoI_cat_euk	582	805
IPR008336	TopoI_DNA-bd_euk	368	579
IPR025834	TopoI_C_dom	844	911

External Links

No external refs found!

At5g55310

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation