At5g67100

Description : DNA polymerase alpha catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9FHA3]

Gene families : OG_42_0006336 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006336_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Arabidopsis release: At5g67100
Cluster	HCCA clusters: Cluster_72

Target	Alias	Description	ECC score	Gene Family Method
Brara.G01198.1	No alias	catalytic component *(POLA1) of DNA polymerase alpha complex	0.06	Orthogroups_2024-Update
Cre04.g214350	No alias	DNA-directed DNA polymerases	0.02	Orthogroups_2024-Update
Glyma.01G187400	No alias	DNA-directed DNA polymerases	0.03	Orthogroups_2024-Update
Kfl00349_0050	kfl00349_0050_v1.1	(o48653\|dpola_orysa : 1124.0) DNA polymerase alpha...	0.02	Orthogroups_2024-Update
evm.model.contig_2084.13	No alias	(o48653\|dpola_orysa : 558.0) DNA polymerase alpha...	0.02	Orthogroups_2024-Update
evm.model.tig00000237.42	No alias	(o48653\|dpola_orysa : 568.0) DNA polymerase alpha...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEA	InterProScan predictions
MF	GO:0001882	nucleoside binding	IEA	InterProScan predictions
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0003887	DNA-directed DNA polymerase activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006260	DNA replication	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016772	transferase activity, transferring phosphorus-containing groups	None	Extended
MF	GO:0016779	nucleotidyltransferase activity	None	Extended
MF	GO:0034061	DNA polymerase activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140097	catalytic activity, acting on DNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000350	generation of catalytic spliceosome for second transesterification step	IEP	Predicted GO
BP	GO:0000726	non-recombinational repair	IEP	Predicted GO
BP	GO:0001510	RNA methylation	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0003743	translation initiation factor activity	IEP	Predicted GO
MF	GO:0003774	motor activity	IEP	Predicted GO
MF	GO:0003777	microtubule motor activity	IEP	Predicted GO
MF	GO:0003899	DNA-directed 5'-3' RNA polymerase activity	IEP	Predicted GO
MF	GO:0004003	ATP-dependent DNA helicase activity	IEP	Predicted GO
MF	GO:0004386	helicase activity	IEP	Predicted GO
MF	GO:0004527	exonuclease activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
CC	GO:0005852	eukaryotic translation initiation factor 3 complex	IEP	Predicted GO
BP	GO:0006270	DNA replication initiation	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006298	mismatch repair	IEP	Predicted GO
BP	GO:0006302	double-strand break repair	IEP	Predicted GO
BP	GO:0006303	double-strand break repair via nonhomologous end joining	IEP	Predicted GO
BP	GO:0006351	transcription, DNA-templated	IEP	Predicted GO
BP	GO:0006364	rRNA processing	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006928	movement of cell or subcellular component	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
BP	GO:0007017	microtubule-based process	IEP	Predicted GO
BP	GO:0007018	microtubule-based movement	IEP	Predicted GO
MF	GO:0008017	microtubule binding	IEP	Predicted GO
MF	GO:0008026	ATP-dependent helicase activity	IEP	Predicted GO
MF	GO:0008092	cytoskeletal protein binding	IEP	Predicted GO
MF	GO:0008094	DNA-dependent ATPase activity	IEP	Predicted GO
MF	GO:0008135	translation factor activity, RNA binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008408	3'-5' exonuclease activity	IEP	Predicted GO
BP	GO:0010639	negative regulation of organelle organization	IEP	Predicted GO
MF	GO:0015631	tubulin binding	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
BP	GO:0016072	rRNA metabolic process	IEP	Predicted GO
MF	GO:0016307	phosphatidylinositol phosphate kinase activity	IEP	Predicted GO
CC	GO:0016459	myosin complex	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0022618	ribonucleoprotein complex assembly	IEP	Predicted GO
BP	GO:0030488	tRNA methylation	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0030684	preribosome	IEP	Predicted GO
MF	GO:0030983	mismatched DNA binding	IEP	Predicted GO
MF	GO:0031369	translation initiation factor binding	IEP	Predicted GO
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Predicted GO
CC	GO:0032040	small-subunit processome	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
BP	GO:0033043	regulation of organelle organization	IEP	Predicted GO
BP	GO:0033044	regulation of chromosome organization	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
MF	GO:0034062	5'-3' RNA polymerase activity	IEP	Predicted GO
BP	GO:0034470	ncRNA processing	IEP	Predicted GO
BP	GO:0034660	ncRNA metabolic process	IEP	Predicted GO
CC	GO:0034708	methyltransferase complex	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
CC	GO:0042555	MCM complex	IEP	Predicted GO
MF	GO:0042623	ATPase activity, coupled	IEP	Predicted GO
BP	GO:0043086	negative regulation of catalytic activity	IEP	Predicted GO
MF	GO:0043138	3'-5' DNA helicase activity	IEP	Predicted GO
MF	GO:0043140	ATP-dependent 3'-5' DNA helicase activity	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043527	tRNA methyltransferase complex	IEP	Predicted GO
BP	GO:0044092	negative regulation of molecular function	IEP	Predicted GO
CC	GO:0044422	organelle part	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044428	nuclear part	IEP	Predicted GO
CC	GO:0044430	cytoskeletal part	IEP	Predicted GO
CC	GO:0044446	intracellular organelle part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
BP	GO:0051095	regulation of helicase activity	IEP	Predicted GO
BP	GO:0051097	negative regulation of helicase activity	IEP	Predicted GO
BP	GO:0051129	negative regulation of cellular component organization	IEP	Predicted GO
BP	GO:0051336	regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0051346	negative regulation of hydrolase activity	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
MF	GO:0070035	purine NTP-dependent helicase activity	IEP	Predicted GO
BP	GO:0071826	ribonucleoprotein complex subunit organization	IEP	Predicted GO
BP	GO:0097659	nucleic acid-templated transcription	IEP	Predicted GO
MF	GO:0097747	RNA polymerase activity	IEP	Predicted GO
BP	GO:1905462	regulation of DNA duplex unwinding	IEP	Predicted GO
BP	GO:1905463	negative regulation of DNA duplex unwinding	IEP	Predicted GO
BP	GO:1905774	regulation of DNA helicase activity	IEP	Predicted GO
BP	GO:1905775	negative regulation of DNA helicase activity	IEP	Predicted GO
BP	GO:2001251	negative regulation of chromosome organization	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006134	DNA-dir_DNA_pol_B_multi_dom	817	1278
IPR006133	DNA-dir_DNA_pol_B_exonuc	374	750
IPR015088	Znf_DNA-dir_DNA_pol_B_alpha	1317	1522
IPR024647	DNA_pol_a_cat_su_N	26	97

External Links

No external refs found!

At5g67100

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation