evm.model.tig00000480.11

Description : (at3g05210 : 203.0) encodes a homolog of human ERCC1 protein (yeast RAD10), which is a DNA repair endonuclease. Mutants are sensitive to UV-B and gamma radiation (G2 cell cycle phase arrest) and are defective in dark-repair of pyrimidine pyrimidone dimers. This protein incises the 5' end of damaged DNA, similar to ERCC1/RAD10.; ERCC1; FUNCTIONS IN: 5'-flap endonuclease activity; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Helix-hairpin-helix DNA-binding motif, class 1 (InterPro:IPR003583), DNA repair protein rad10 (InterPro:IPR004579), RuvA domain 2-like (InterPro:IPR010994); Has 658 Blast hits to 452 proteins in 188 species: Archae - 0; Bacteria - 4; Metazoa - 166; Fungi - 153; Plants - 44; Viruses - 0; Other Eukaryotes - 291 (source: NCBI BLink). & (reliability: 406.0) & (original description: no original description)

Gene families : OG_42_0008310 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0008310_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00000480.11
Cluster	HCCA clusters: Cluster_92

Target	Alias	Description	ECC score	Gene Family Method	Actions
Pp1s117_170V6	No alias	excision repair cross-complementing 1	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	None	Extended
MF	GO:0003684	damaged DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005634	nucleus	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006259	DNA metabolic process	None	Extended
BP	GO:0006281	DNA repair	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0006950	response to stress	None	Extended
BP	GO:0006974	cellular response to DNA damage stimulus	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
BP	GO:0033554	cellular response to stress	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043227	membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043231	intracellular membrane-bounded organelle	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0050896	response to stimulus	None	Extended
BP	GO:0051716	cellular response to stimulus	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000148	1,3-beta-D-glucan synthase complex	IEP	Predicted GO
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
BP	GO:0000271	polysaccharide biosynthetic process	IEP	Predicted GO
MF	GO:0003843	1,3-beta-D-glucan synthase activity	IEP	Predicted GO
MF	GO:0005049	nuclear export signal receptor activity	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
CC	GO:0005694	chromosome	IEP	Predicted GO
BP	GO:0005976	polysaccharide metabolic process	IEP	Predicted GO
BP	GO:0006073	cellular glucan metabolic process	IEP	Predicted GO
BP	GO:0006074	(1->3)-beta-D-glucan metabolic process	IEP	Predicted GO
BP	GO:0006075	(1->3)-beta-D-glucan biosynthetic process	IEP	Predicted GO
BP	GO:0006996	organelle organization	IEP	Predicted GO
BP	GO:0007062	sister chromatid cohesion	IEP	Predicted GO
BP	GO:0007064	mitotic sister chromatid cohesion	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008194	UDP-glycosyltransferase activity	IEP	Predicted GO
BP	GO:0009250	glucan biosynthetic process	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	IEP	Predicted GO
MF	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0017025	TBP-class protein binding	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
BP	GO:0022402	cell cycle process	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
CC	GO:0031390	Ctf18 RFC-like complex	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
BP	GO:0033692	cellular polysaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0034637	cellular carbohydrate biosynthetic process	IEP	Predicted GO
MF	GO:0035251	UDP-glucosyltransferase activity	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0044042	glucan metabolic process	IEP	Predicted GO
BP	GO:0044262	cellular carbohydrate metabolic process	IEP	Predicted GO
BP	GO:0044264	cellular polysaccharide metabolic process	IEP	Predicted GO
CC	GO:0044459	plasma membrane part	IEP	Predicted GO
MF	GO:0046527	glucosyltransferase activity	IEP	Predicted GO
MF	GO:0051213	dioxygenase activity	IEP	Predicted GO
BP	GO:0051273	beta-glucan metabolic process	IEP	Predicted GO
BP	GO:0051274	beta-glucan biosynthetic process	IEP	Predicted GO
BP	GO:0051276	chromosome organization	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
CC	GO:0098797	plasma membrane protein complex	IEP	Predicted GO
MF	GO:0140104	molecular carrier activity	IEP	Predicted GO
MF	GO:0140142	nucleocytoplasmic carrier activity	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
BP	GO:1903047	mitotic cell cycle process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR004579	ERCC1/RAD10/SWI10	189	301

External Links

No external refs found!

evm.model.tig00000480.11

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation