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  5. evm.model.tig00000704.52

evm.model.tig00000704.52


Description : (at2g32920 : 121.0) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.; PDI-like 2-3 (PDIL2-3); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress; LOCATED IN: endoplasmic reticulum, plasma membrane, vacuole; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 34824 Blast hits to 18409 proteins in 2879 species: Archae - 382; Bacteria - 17291; Metazoa - 5423; Fungi - 1895; Plants - 2648; Viruses - 40; Other Eukaryotes - 7145 (source: NCBI BLink). & (p38661|pdia6_medsa : 97.4) Probable protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (P5) - Medicago sativa (Alfalfa) & (reliability: 242.0) & (original description: no original description)


Gene families : OG_42_0005698 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005698_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00000704.52
Cluster HCCA clusters: Cluster_22

Target Alias Description ECC score Gene Family Method Actions
At1g04980 No alias Protein disulfide-isomerase like 2-2... 0.02 Orthogroups_2024-Update
Brara.E01104.1 No alias protein disulfide isomerase *(PDI-M) 0.03 Orthogroups_2024-Update
Brara.J00316.1 No alias protein disulfide isomerase *(PDI-M) & protein disulfide... 0.01 Orthogroups_2024-Update
GRMZM2G376542 No alias PDI-like 2-3 0.03 Orthogroups_2024-Update
GRMZM2G389173 No alias PDI-like 2-2 0.03 Orthogroups_2024-Update
LOC_Os09g27830 No alias OsPDIL2-3 protein disulfide isomerase PDIL2-3, expressed 0.01 Orthogroups_2024-Update
MA_12242g0010 No alias (at1g04980 : 618.0) Encodes a protein disulfide... 0.02 Orthogroups_2024-Update
Mp4g17970.1 No alias protein disulfide isomerase (PDI-M) 0.01 Orthogroups_2024-Update
Sopen07g024800 No alias Thioredoxin 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0045454 cell redox homeostasis IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0000339 RNA cap binding IEP Predicted GO
MF GO:0000340 RNA 7-methylguanosine cap binding IEP Predicted GO
MF GO:0003674 molecular_function IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003729 mRNA binding IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0004175 endopeptidase activity IEP Predicted GO
MF GO:0004190 aspartic-type endopeptidase activity IEP Predicted GO
MF GO:0004298 threonine-type endopeptidase activity IEP Predicted GO
MF GO:0004357 glutamate-cysteine ligase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0004518 nuclease activity IEP Predicted GO
MF GO:0004525 ribonuclease III activity IEP Predicted GO
MF GO:0004576 oligosaccharyl transferase activity IEP Predicted GO
MF GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity IEP Predicted GO
MF GO:0004618 phosphoglycerate kinase activity IEP Predicted GO
MF GO:0004664 prephenate dehydratase activity IEP Predicted GO
MF GO:0004807 triose-phosphate isomerase activity IEP Predicted GO
MF GO:0004843 thiol-dependent ubiquitin-specific protease activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
CC GO:0005789 endoplasmic reticulum membrane IEP Predicted GO
CC GO:0005839 proteasome core complex IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006486 protein glycosylation IEP Predicted GO
BP GO:0006487 protein N-linked glycosylation IEP Predicted GO
BP GO:0006508 proteolysis IEP Predicted GO
BP GO:0006511 ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0006558 L-phenylalanine metabolic process IEP Predicted GO
BP GO:0006749 glutathione metabolic process IEP Predicted GO
BP GO:0006750 glutathione biosynthetic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009094 L-phenylalanine biosynthetic process IEP Predicted GO
BP GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway IEP Predicted GO
BP GO:0016053 organic acid biosynthetic process IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
MF GO:0016774 phosphotransferase activity, carboxyl group as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016860 intramolecular oxidoreductase activity IEP Predicted GO
MF GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0017144 drug metabolic process IEP Predicted GO
BP GO:0018193 peptidyl-amino acid modification IEP Predicted GO
BP GO:0018196 peptidyl-asparagine modification IEP Predicted GO
BP GO:0018279 protein N-linked glycosylation via asparagine IEP Predicted GO
BP GO:0019184 nonribosomal peptide biosynthetic process IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
CC GO:0019773 proteasome core complex, alpha-subunit complex IEP Predicted GO
BP GO:0019941 modification-dependent protein catabolic process IEP Predicted GO
CC GO:0030118 clathrin coat IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030125 clathrin vesicle coat IEP Predicted GO
CC GO:0030130 clathrin coat of trans-Golgi network vesicle IEP Predicted GO
CC GO:0030132 clathrin coat of coated pit IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0032296 double-stranded RNA-specific ribonuclease activity IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
CC GO:0035145 exon-exon junction complex IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0042398 cellular modified amino acid biosynthetic process IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0043413 macromolecule glycosylation IEP Predicted GO
BP GO:0043632 modification-dependent macromolecule catabolic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044265 cellular macromolecule catabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0046394 carboxylic acid biosynthetic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0051603 proteolysis involved in cellular protein catabolic process IEP Predicted GO
MF GO:0070001 aspartic-type peptidase activity IEP Predicted GO
MF GO:0070003 threonine-type peptidase activity IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0070085 glycosylation IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1902221 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process IEP Predicted GO
BP GO:1902223 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 27 116
No external refs found!