evm.model.tig00000880.13


Description : (at4g15900 : 448.0) Mutations confer hypersensitivity to glucose and sucrose and augments sensitivity to cytokinin, ethylene, ABA and auxin. Encodes a nuclear WD40 protein that is imported into the nucleus. Essential for plant innate immunity. Interacts with MOS4 and AtCDC5. It is also predicted to have two DWD motifs. It can bind to DDB1a in Y2H assays, and DDB1b in co-IP assays, and may be involved in the formation of a CUL4-based E3 ubiquitin ligase, and may affect the stability of AKIN10.; pleiotropic regulatory locus 1 (PRL1); CONTAINS InterPro DOMAIN/s: WD40 repeat 2 (InterPro:IPR019782), WD40 repeat, conserved site (InterPro:IPR019775), WD40 repeat (InterPro:IPR001680), G-protein beta WD-40 repeat, region (InterPro:IPR020472), WD40 repeat-like-containing domain (InterPro:IPR011046), WD40-repeat-containing domain (InterPro:IPR017986), WD40/YVTN repeat-like-containing domain (InterPro:IPR015943), WD40 repeat, subgroup (InterPro:IPR019781); BEST Arabidopsis thaliana protein match is: Transducin/WD40 repeat-like superfamily protein (TAIR:AT3G16650.1); Has 84704 Blast hits to 34179 proteins in 878 species: Archae - 64; Bacteria - 9610; Metazoa - 34201; Fungi - 18356; Plants - 10881; Viruses - 0; Other Eukaryotes - 11592 (source: NCBI BLink). & (p93107|pf20_chlre : 106.0) Flagellar WD repeat protein PF20 - Chlamydomonas reinhardtii & (reliability: 862.0) & (original description: no original description)


Gene families : OG_42_0006425 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006425_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00000880.13
Cluster HCCA clusters: Cluster_49

Target Alias Description ECC score Gene Family Method Actions
At4g15900 No alias Protein pleiotropic regulatory locus 1... 0.02 Orthogroups_2024-Update
Cre10.g446900 No alias pleiotropic regulatory locus 1 0.01 Orthogroups_2024-Update
LOC_Os03g21990 No alias WD domain, G-beta repeat domain containing protein, expressed 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
MF GO:0004252 serine-type endopeptidase activity IEP Predicted GO
MF GO:0004363 glutathione synthase activity IEP Predicted GO
MF GO:0004521 endoribonuclease activity IEP Predicted GO
MF GO:0004525 ribonuclease III activity IEP Predicted GO
MF GO:0004843 thiol-dependent ubiquitin-specific protease activity IEP Predicted GO
BP GO:0006396 RNA processing IEP Predicted GO
BP GO:0006575 cellular modified amino acid metabolic process IEP Predicted GO
BP GO:0006749 glutathione metabolic process IEP Predicted GO
BP GO:0006750 glutathione biosynthetic process IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
MF GO:0008658 penicillin binding IEP Predicted GO
MF GO:0016757 transferase activity, transferring glycosyl groups IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016881 acid-amino acid ligase activity IEP Predicted GO
MF GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
BP GO:0019184 nonribosomal peptide biosynthetic process IEP Predicted GO
BP GO:0030258 lipid modification IEP Predicted GO
BP GO:0030259 lipid glycosylation IEP Predicted GO
MF GO:0031406 carboxylic acid binding IEP Predicted GO
MF GO:0032296 double-stranded RNA-specific ribonuclease activity IEP Predicted GO
MF GO:0033218 amide binding IEP Predicted GO
MF GO:0033293 monocarboxylic acid binding IEP Predicted GO
BP GO:0042398 cellular modified amino acid biosynthetic process IEP Predicted GO
MF GO:0043177 organic acid binding IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
MF GO:1901681 sulfur compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001680 WD40_repeat 203 239
IPR001680 WD40_repeat 117 155
IPR001680 WD40_repeat 327 363
IPR001680 WD40_repeat 162 197
IPR001680 WD40_repeat 245 281
No external refs found!