evm.model.tig00000889.36


Description : (at4g26970 : 101.0) Encodes an aconitase that can catalyze the conversion of citrate to isocitrate through a cis-aconitate intermediate, indicating that it may participate in the TCA cycle and other primary metabolic pathways. The protein is believed to accumulate in the mitochondria and the cytosol. It affects CSD2 (At2g28190 - a superoxide dismutase) transcript levels and may play a role in the response to oxidative stress. One member of the family (ACO1 - At35830) was shown to specifically bind to the 5' UTR of CSD2 in vitro.; aconitase 2 (ACO2); FUNCTIONS IN: aconitate hydratase activity, copper ion binding; INVOLVED IN: response to oxidative stress, response to cadmium ion, isocitrate metabolic process, citrate metabolic process; LOCATED IN: cytosol, mitochondrion, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 17 growth stages; CONTAINS InterPro DOMAIN/s: Aconitase family, 4Fe-4S cluster binding site (InterPro:IPR018136), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha (InterPro:IPR001030), Aconitase A/isopropylmalate dehydratase small subunit, swivel (InterPro:IPR000573), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 (InterPro:IPR015932), Aconitase/Iron regulatory protein 2/2-methylisocitrate dehydratase (InterPro:IPR015934), Aconitase/3-isopropylmalate dehydratase, swivel (InterPro:IPR015928), Aconitase-like core (InterPro:IPR015937), Aconitase/iron regulatory protein 2 (InterPro:IPR006249), Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 (InterPro:IPR015931); BEST Arabidopsis thaliana protein match is: aconitase 3 (TAIR:AT2G05710.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q6yzx6|acoc_orysa : 98.2) Putative aconitate hydratase, cytoplasmic (EC 4.2.1.3) (Citrate hydro-lyase) (Aconitase) - Oryza sativa (Rice) & (reliability: 202.0) & (original description: no original description)


Gene families : OG_42_0001446 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001446_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00000889.36
Cluster HCCA clusters: Cluster_27

Target Alias Description ECC score Gene Family Method Actions
Glyma.13G308700 No alias aconitase 3 0.01 Orthogroups_2024-Update
Pp1s131_178V6 No alias T3P4.5; aconitate hydratase, cytoplasmic, putative /... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0003674 molecular_function IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0004857 enzyme inhibitor activity IEP Predicted GO
MF GO:0004866 endopeptidase inhibitor activity IEP Predicted GO
MF GO:0004867 serine-type endopeptidase inhibitor activity IEP Predicted GO
MF GO:0005534 galactose binding IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006066 alcohol metabolic process IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008171 O-methyltransferase activity IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
MF GO:0008716 D-alanine-D-alanine ligase activity IEP Predicted GO
BP GO:0009611 response to wounding IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0016579 protein deubiquitination IEP Predicted GO
MF GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016740 transferase activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
BP GO:0019751 polyol metabolic process IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
MF GO:0030234 enzyme regulator activity IEP Predicted GO
MF GO:0030414 peptidase inhibitor activity IEP Predicted GO
BP GO:0032958 inositol phosphate biosynthetic process IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0043647 inositol phosphate metabolic process IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
BP GO:0046165 alcohol biosynthetic process IEP Predicted GO
BP GO:0046173 polyol biosynthetic process IEP Predicted GO
MF GO:0048029 monosaccharide binding IEP Predicted GO
MF GO:0061134 peptidase regulator activity IEP Predicted GO
MF GO:0061135 endopeptidase regulator activity IEP Predicted GO
MF GO:0070569 uridylyltransferase activity IEP Predicted GO
BP GO:0070646 protein modification by small protein removal IEP Predicted GO
BP GO:0070647 protein modification by small protein conjugation or removal IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1901617 organic hydroxy compound biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000573 AconitaseA/IPMdHydase_ssu_swvl 436 469
IPR000573 AconitaseA/IPMdHydase_ssu_swvl 359 435
IPR001030 Acoase/IPM_deHydtase_lsu_aba 1 287
No external refs found!