Description : (at5g41360 : 573.0) Encodes XPB2, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.; homolog of Xeroderma pigmentosum complementation group B 2 (XPB2); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV-B, N-terminal protein myristoylation; EXPRESSED IN: whole plant; EXPRESSED DURING: seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of xeroderma pigmentosum complementation group B 1 (TAIR:AT5G41370.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 1146.0) & (original description: no original description)
Gene families : OG_42_0003616 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003616_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00000949.17 | |
Cluster | HCCA clusters: Cluster_164 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Cre06.g297016 | No alias | homolog of Xeroderma pigmentosum complementation group B 2 | 0.02 | Orthogroups_2024-Update | |
Glyma.05G209700 | No alias | homolog of xeroderma pigmentosum complementation group B 1 | 0.02 | Orthogroups_2024-Update | |
evm.model.contig_3597.6 | No alias | (at5g41360 : 736.0) Encodes XPB2, a DNA repair protein... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0003677 | DNA binding | IEA | InterProScan predictions |
MF | GO:0005524 | ATP binding | IEA | InterProScan predictions |
MF | GO:0016787 | hydrolase activity | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000723 | telomere maintenance | IEP | Predicted GO |
MF | GO:0003678 | DNA helicase activity | IEP | Predicted GO |
MF | GO:0008194 | UDP-glycosyltransferase activity | IEP | Predicted GO |
MF | GO:0008234 | cysteine-type peptidase activity | IEP | Predicted GO |
MF | GO:0008375 | acetylglucosaminyltransferase activity | IEP | Predicted GO |
CC | GO:0016020 | membrane | IEP | Predicted GO |
MF | GO:0016462 | pyrophosphatase activity | IEP | Predicted GO |
MF | GO:0016774 | phosphotransferase activity, carboxyl group as acceptor | IEP | Predicted GO |
MF | GO:0016817 | hydrolase activity, acting on acid anhydrides | IEP | Predicted GO |
MF | GO:0016818 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | IEP | Predicted GO |
MF | GO:0016887 | ATPase activity | IEP | Predicted GO |
MF | GO:0017111 | nucleoside-triphosphatase activity | IEP | Predicted GO |
MF | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity | IEP | Predicted GO |
BP | GO:0032200 | telomere organization | IEP | Predicted GO |
BP | GO:0060249 | anatomical structure homeostasis | IEP | Predicted GO |
No external refs found! |