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  5. evm.model.tig00001038.3

evm.model.tig00001038.3


Description : (at2g47470 : 270.0) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.; UNFERTILIZED EMBRYO SAC 5 (UNE5); FUNCTIONS IN: protein disulfide isomerase activity; INVOLVED IN: response to endoplasmic reticulum stress, double fertilization forming a zygote and endosperm, embryo sac development, pollen tube development, embryo development ending in seed dormancy; LOCATED IN: endoplasmic reticulum, plasma membrane, plant-type cell wall; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Endoplasmic reticulum, protein ERp29, C-terminal (InterPro:IPR011679), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-2 (TAIR:AT1G04980.1); Has 37639 Blast hits to 19288 proteins in 2969 species: Archae - 403; Bacteria - 17566; Metazoa - 6414; Fungi - 2106; Plants - 3416; Viruses - 32; Other Eukaryotes - 7702 (source: NCBI BLink). & (p38661|pdia6_medsa : 270.0) Probable protein disulfide-isomerase A6 precursor (EC 5.3.4.1) (P5) - Medicago sativa (Alfalfa) & (reliability: 540.0) & (original description: no original description)


Gene families : OG_42_0003293 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003293_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00001038.3
Cluster HCCA clusters: Cluster_22

Target Alias Description ECC score Gene Family Method Actions
Bradi2g12560 No alias thioredoxin family protein 0.01 Orthogroups_2024-Update
Glyma.10G014700 No alias thioredoxin family protein 0.02 Orthogroups_2024-Update
Seita.5G160100.1 No alias protein disulfide isomerase *(PDI-S) & protein disulfide... 0.05 Orthogroups_2024-Update
Seita.7G268600.1 No alias protein disulfide isomerase *(PDI-S) & protein disulfide... 0.05 Orthogroups_2024-Update
Solyc01g100320 No alias Disulfide-isomerase-like protein (AHRD V3.3 *** Q38JJ2_SOLTU) 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
CC GO:0005783 endoplasmic reticulum IEA InterProScan predictions
BP GO:0045454 cell redox homeostasis IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000149 SNARE binding IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003674 molecular_function IEP Predicted GO
MF GO:0005048 signal sequence binding IEP Predicted GO
MF GO:0005096 GTPase activator activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005681 spliceosomal complex IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0006457 protein folding IEP Predicted GO
BP GO:0006605 protein targeting IEP Predicted GO
BP GO:0006612 protein targeting to membrane IEP Predicted GO
BP GO:0006613 cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane IEP Predicted GO
BP GO:0006621 protein retention in ER lumen IEP Predicted GO
MF GO:0008047 enzyme activator activity IEP Predicted GO
MF GO:0008138 protein tyrosine/serine/threonine phosphatase activity IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008312 7S RNA binding IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
CC GO:0016272 prefoldin complex IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0019905 syntaxin binding IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030695 GTPase regulator activity IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
BP GO:0032507 maintenance of protein location in cell IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0032774 RNA biosynthetic process IEP Predicted GO
CC GO:0032991 protein-containing complex IEP Predicted GO
MF GO:0033218 amide binding IEP Predicted GO
BP GO:0033365 protein localization to organelle IEP Predicted GO
BP GO:0034613 cellular protein localization IEP Predicted GO
BP GO:0035437 maintenance of protein localization in endoplasmic reticulum IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0042277 peptide binding IEP Predicted GO
MF GO:0043015 gamma-tubulin binding IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
CC GO:0044428 nuclear part IEP Predicted GO
BP GO:0045047 protein targeting to ER IEP Predicted GO
BP GO:0045185 maintenance of protein location IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
MF GO:0046923 ER retention sequence binding IEP Predicted GO
CC GO:0048500 signal recognition particle IEP Predicted GO
MF GO:0051082 unfolded protein binding IEP Predicted GO
BP GO:0051235 maintenance of location IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0051651 maintenance of location in cell IEP Predicted GO
MF GO:0060589 nucleoside-triphosphatase regulator activity IEP Predicted GO
BP GO:0070727 cellular macromolecule localization IEP Predicted GO
BP GO:0070972 protein localization to endoplasmic reticulum IEP Predicted GO
BP GO:0072594 establishment of protein localization to organelle IEP Predicted GO
BP GO:0072595 maintenance of protein localization in organelle IEP Predicted GO
BP GO:0072599 establishment of protein localization to endoplasmic reticulum IEP Predicted GO
BP GO:0072657 protein localization to membrane IEP Predicted GO
BP GO:0090150 establishment of protein localization to membrane IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
CC GO:1990904 ribonucleoprotein complex IEP Predicted GO
InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 22 124
IPR013766 Thioredoxin_domain 142 251
IPR011679 ERp29_C 276 331
No external refs found!