evm.model.tig00001071.13


Description : (at5g50320 : 728.0) A subunit of Elongator, a histone acetyl transferase complex, consisting of six subunits (ELP1ñELP6), that copurifies with the elongating RNAPII in yeast and humans. Three Arabidopsis thaliana genes, encoding homologs of the yeast Elongator subunits ELP1, ELP3 (histone acetyl transferase), and ELP4 are responsible for the narrow leaf phenotype in elongata mutants and for reduced root growth that results from a decreased cell division rate. Two lines with RNAi constructs directed against HAG3 grow normally and can produce root calli, but have defects in agrobacterium-mediated transformation.; ELONGATA 3 (ELO3); CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Histone acetyltransferase ELP3 (InterPro:IPR005910), Radical SAM (InterPro:IPR007197), Acyl-CoA N-acyltransferase (InterPro:IPR016181); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q7x7l3|elp3_orysa : 724.0) Probable histone acetyltransferase ELP3 (EC 2.3.1.48) (Elongator component 3) (Elongation protein 3) - Oryza sativa (Rice) & (reliability: 1456.0) & (original description: no original description)


Gene families : OG_42_0004000 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004000_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00001071.13
Cluster HCCA clusters: Cluster_95

Target Alias Description ECC score Gene Family Method Actions
Pp1s185_41V6 No alias histone acetyltransferase 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003824 catalytic activity IEA InterProScan predictions
MF GO:0051536 iron-sulfur cluster binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003951 NAD+ kinase activity IEP Predicted GO
MF GO:0004590 orotidine-5'-phosphate decarboxylase activity IEP Predicted GO
MF GO:0004649 poly(ADP-ribose) glycohydrolase activity IEP Predicted GO
BP GO:0006206 pyrimidine nucleobase metabolic process IEP Predicted GO
BP GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006739 NADP metabolic process IEP Predicted GO
BP GO:0006741 NADP biosynthetic process IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008173 RNA methyltransferase activity IEP Predicted GO
MF GO:0008483 transaminase activity IEP Predicted GO
BP GO:0009112 nucleobase metabolic process IEP Predicted GO
BP GO:0009116 nucleoside metabolic process IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016769 transferase activity, transferring nitrogenous groups IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016830 carbon-carbon lyase activity IEP Predicted GO
MF GO:0016831 carboxy-lyase activity IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019856 pyrimidine nucleobase biosynthetic process IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0046112 nucleobase biosynthetic process IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
MF GO:0051287 NAD binding IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
MF GO:0070403 NAD+ binding IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901657 glycosyl compound metabolic process IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR007197 rSAM 167 298
IPR000182 GNAT_dom 368 500
No external refs found!