Description : (at3g54610 : 130.0) Encodes a histone acetyltransferase that is plays a role in the determination of the embryonic root-shoot axis. It is also required to regulate the floral meristem activity by modulating the extent of expression of WUS and AG. In other eukaryotes, this protein is recruited to specific promoters by DNA binding transcription factors and is thought to promote transcription by acetylating the N-terminal tail of histone H3. The enzyme has indeed been shown to catalyse primarily the acetylation of H3 histone with only traces of H4 and H2A/B being acetylated. Non-acetylated H3 peptide or an H3 peptide that had been previously acetylated on K9 both serve as excellent substrates for HAG1-catalyzed acetylation. However, prior acetylation of H3 lysine 14 blocks radioactive acetylation of the peptide by HAG1. HAG1 is specific for histone H3 lysine 14.; histone acetyltransferase of the GNAT family 1 (HAG1); FUNCTIONS IN: histone acetyltransferase activity, DNA binding, H3 histone acetyltransferase activity; INVOLVED IN: flower development, histone acetylation, response to light stimulus, positive regulation of transcription, root morphogenesis; LOCATED IN: histone acetyltransferase complex, nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Bromodomain, conserved site (InterPro:IPR018359), Acyl-CoA N-acyltransferase (InterPro:IPR016181), Bromodomain (InterPro:IPR001487); BEST Arabidopsis thaliana protein match is: nuclear protein X1 (TAIR:AT5G63320.1); Has 13698 Blast hits to 5805 proteins in 367 species: Archae - 4; Bacteria - 1437; Metazoa - 4852; Fungi - 1484; Plants - 516; Viruses - 1; Other Eukaryotes - 5404 (source: NCBI BLink). & (reliability: 260.0) & (original description: no original description)
Gene families : OG_42_0004766 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004766_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00001085.33 | |
Cluster | HCCA clusters: Cluster_49 |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
BP | GO:0000375 | RNA splicing, via transesterification reactions | IEP | Predicted GO |
BP | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | IEP | Predicted GO |
BP | GO:0000398 | mRNA splicing, via spliceosome | IEP | Predicted GO |
MF | GO:0003774 | motor activity | IEP | Predicted GO |
MF | GO:0003777 | microtubule motor activity | IEP | Predicted GO |
MF | GO:0004363 | glutathione synthase activity | IEP | Predicted GO |
MF | GO:0004843 | thiol-dependent ubiquitin-specific protease activity | IEP | Predicted GO |
BP | GO:0006575 | cellular modified amino acid metabolic process | IEP | Predicted GO |
BP | GO:0006749 | glutathione metabolic process | IEP | Predicted GO |
BP | GO:0006750 | glutathione biosynthetic process | IEP | Predicted GO |
BP | GO:0006778 | porphyrin-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0006779 | porphyrin-containing compound biosynthetic process | IEP | Predicted GO |
BP | GO:0006928 | movement of cell or subcellular component | IEP | Predicted GO |
BP | GO:0007017 | microtubule-based process | IEP | Predicted GO |
BP | GO:0007018 | microtubule-based movement | IEP | Predicted GO |
MF | GO:0008017 | microtubule binding | IEP | Predicted GO |
MF | GO:0008092 | cytoskeletal protein binding | IEP | Predicted GO |
MF | GO:0008233 | peptidase activity | IEP | Predicted GO |
MF | GO:0008234 | cysteine-type peptidase activity | IEP | Predicted GO |
BP | GO:0008380 | RNA splicing | IEP | Predicted GO |
MF | GO:0015631 | tubulin binding | IEP | Predicted GO |
BP | GO:0015994 | chlorophyll metabolic process | IEP | Predicted GO |
BP | GO:0015995 | chlorophyll biosynthetic process | IEP | Predicted GO |
MF | GO:0016787 | hydrolase activity | IEP | Predicted GO |
MF | GO:0016881 | acid-amino acid ligase activity | IEP | Predicted GO |
BP | GO:0019184 | nonribosomal peptide biosynthetic process | IEP | Predicted GO |
MF | GO:0019783 | ubiquitin-like protein-specific protease activity | IEP | Predicted GO |
MF | GO:0031625 | ubiquitin protein ligase binding | IEP | Predicted GO |
BP | GO:0033014 | tetrapyrrole biosynthetic process | IEP | Predicted GO |
MF | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity | IEP | Predicted GO |
BP | GO:0042398 | cellular modified amino acid biosynthetic process | IEP | Predicted GO |
BP | GO:0042440 | pigment metabolic process | IEP | Predicted GO |
BP | GO:0044272 | sulfur compound biosynthetic process | IEP | Predicted GO |
MF | GO:0044389 | ubiquitin-like protein ligase binding | IEP | Predicted GO |
BP | GO:0046148 | pigment biosynthetic process | IEP | Predicted GO |
BP | GO:0051186 | cofactor metabolic process | IEP | Predicted GO |
BP | GO:0051188 | cofactor biosynthetic process | IEP | Predicted GO |
MF | GO:0070011 | peptidase activity, acting on L-amino acid peptides | IEP | Predicted GO |
MF | GO:0101005 | ubiquitinyl hydrolase activity | IEP | Predicted GO |
No external refs found! |