evm.model.tig00001085.33


Description : (at3g54610 : 130.0) Encodes a histone acetyltransferase that is plays a role in the determination of the embryonic root-shoot axis. It is also required to regulate the floral meristem activity by modulating the extent of expression of WUS and AG. In other eukaryotes, this protein is recruited to specific promoters by DNA binding transcription factors and is thought to promote transcription by acetylating the N-terminal tail of histone H3. The enzyme has indeed been shown to catalyse primarily the acetylation of H3 histone with only traces of H4 and H2A/B being acetylated. Non-acetylated H3 peptide or an H3 peptide that had been previously acetylated on K9 both serve as excellent substrates for HAG1-catalyzed acetylation. However, prior acetylation of H3 lysine 14 blocks radioactive acetylation of the peptide by HAG1. HAG1 is specific for histone H3 lysine 14.; histone acetyltransferase of the GNAT family 1 (HAG1); FUNCTIONS IN: histone acetyltransferase activity, DNA binding, H3 histone acetyltransferase activity; INVOLVED IN: flower development, histone acetylation, response to light stimulus, positive regulation of transcription, root morphogenesis; LOCATED IN: histone acetyltransferase complex, nucleus; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage, E expanded cotyledon stage; CONTAINS InterPro DOMAIN/s: GCN5-related N-acetyltransferase, C-terminal (InterPro:IPR022610), GCN5-related N-acetyltransferase (InterPro:IPR000182), Bromodomain, conserved site (InterPro:IPR018359), Acyl-CoA N-acyltransferase (InterPro:IPR016181), Bromodomain (InterPro:IPR001487); BEST Arabidopsis thaliana protein match is: nuclear protein X1 (TAIR:AT5G63320.1); Has 13698 Blast hits to 5805 proteins in 367 species: Archae - 4; Bacteria - 1437; Metazoa - 4852; Fungi - 1484; Plants - 516; Viruses - 1; Other Eukaryotes - 5404 (source: NCBI BLink). & (reliability: 260.0) & (original description: no original description)


Gene families : OG_42_0004766 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004766_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00001085.33
Cluster HCCA clusters: Cluster_49


Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000375 RNA splicing, via transesterification reactions IEP Predicted GO
BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile IEP Predicted GO
BP GO:0000398 mRNA splicing, via spliceosome IEP Predicted GO
MF GO:0003774 motor activity IEP Predicted GO
MF GO:0003777 microtubule motor activity IEP Predicted GO
MF GO:0004363 glutathione synthase activity IEP Predicted GO
MF GO:0004843 thiol-dependent ubiquitin-specific protease activity IEP Predicted GO
BP GO:0006575 cellular modified amino acid metabolic process IEP Predicted GO
BP GO:0006749 glutathione metabolic process IEP Predicted GO
BP GO:0006750 glutathione biosynthetic process IEP Predicted GO
BP GO:0006778 porphyrin-containing compound metabolic process IEP Predicted GO
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Predicted GO
BP GO:0006928 movement of cell or subcellular component IEP Predicted GO
BP GO:0007017 microtubule-based process IEP Predicted GO
BP GO:0007018 microtubule-based movement IEP Predicted GO
MF GO:0008017 microtubule binding IEP Predicted GO
MF GO:0008092 cytoskeletal protein binding IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
MF GO:0008234 cysteine-type peptidase activity IEP Predicted GO
BP GO:0008380 RNA splicing IEP Predicted GO
MF GO:0015631 tubulin binding IEP Predicted GO
BP GO:0015994 chlorophyll metabolic process IEP Predicted GO
BP GO:0015995 chlorophyll biosynthetic process IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016881 acid-amino acid ligase activity IEP Predicted GO
BP GO:0019184 nonribosomal peptide biosynthetic process IEP Predicted GO
MF GO:0019783 ubiquitin-like protein-specific protease activity IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
BP GO:0033014 tetrapyrrole biosynthetic process IEP Predicted GO
MF GO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEP Predicted GO
BP GO:0042398 cellular modified amino acid biosynthetic process IEP Predicted GO
BP GO:0042440 pigment metabolic process IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
BP GO:0046148 pigment biosynthetic process IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
MF GO:0101005 ubiquitinyl hydrolase activity IEP Predicted GO
InterPro domains Description Start Stop
IPR000182 GNAT_dom 273 329
IPR001487 Bromodomain 390 470
No external refs found!