evm.model.tig00001388.13

Description : (o22101|hemh_orysa : 414.0) Ferrochelatase-2, chloroplast precursor (EC 4.99.1.1) (Ferrochelatase II) (Protoheme ferro-lyase 2) (Heme synthetase 2) - Oryza sativa (Rice) & (at2g30390 : 413.0) Encodes one of two ferrochelatase genes in Arabidopsis. Ferrochelatase is the terminal enzyme of heme biosynthesis. FC-II is speculated to operate in photosynthetic cytochromes; ferrochelatase 2 (FC2); FUNCTIONS IN: ferrochelatase activity; INVOLVED IN: heme biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ferrochelatase (InterPro:IPR001015), Ferrochelatase, active site (InterPro:IPR019772); BEST Arabidopsis thaliana protein match is: ferrochelatase 1 (TAIR:AT5G26030.2). & (reliability: 826.0) & (original description: no original description)

Gene families : OG_42_0002272 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0002272_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00001388.13
Cluster	HCCA clusters: Cluster_182

Target	Alias	Description	ECC score	Gene Family Method
Glyma.04G050400	No alias	ferrochelatase 1	0.02	Orthogroups_2024-Update
Glyma.04G205600	No alias	ferrochelatase 2	0.01	Orthogroups_2024-Update
Glyma.08G005000	No alias	ferrochelatase 2	0.02	Orthogroups_2024-Update
Mp7g00290.1	No alias	ferrochelatase	0.02	Orthogroups_2024-Update
PSME_00018805-RA	No alias	(o22101\|hemh_orysa : 509.0) Ferrochelatase-2,...	0.02	Orthogroups_2024-Update
evm.model.contig_4470.5	No alias	(p42044\|hemh_cucsa : 117.0) Ferrochelatase-2,...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004325	ferrochelatase activity	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006778	porphyrin-containing compound metabolic process	None	Extended
BP	GO:0006779	porphyrin-containing compound biosynthetic process	None	Extended
BP	GO:0006783	heme biosynthetic process	IEA	InterProScan predictions
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
MF	GO:0016829	lyase activity	None	Extended
BP	GO:0018130	heterocycle biosynthetic process	None	Extended
BP	GO:0019438	aromatic compound biosynthetic process	None	Extended
BP	GO:0033013	tetrapyrrole metabolic process	None	Extended
BP	GO:0033014	tetrapyrrole biosynthetic process	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0042168	heme metabolic process	None	Extended
BP	GO:0042440	pigment metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044271	cellular nitrogen compound biosynthetic process	None	Extended
BP	GO:0046148	pigment biosynthetic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0051186	cofactor metabolic process	None	Extended
BP	GO:0051188	cofactor biosynthetic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901362	organic cyclic compound biosynthetic process	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1901566	organonitrogen compound biosynthetic process	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0001932	regulation of protein phosphorylation	IEP	Predicted GO
MF	GO:0003954	NADH dehydrogenase activity	IEP	Predicted GO
MF	GO:0004601	peroxidase activity	IEP	Predicted GO
MF	GO:0004602	glutathione peroxidase activity	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005739	mitochondrion	IEP	Predicted GO
BP	GO:0006801	superoxide metabolic process	IEP	Predicted GO
BP	GO:0006979	response to oxidative stress	IEP	Predicted GO
MF	GO:0008137	NADH dehydrogenase (ubiquinone) activity	IEP	Predicted GO
MF	GO:0009496	plastoquinol--plastocyanin reductase activity	IEP	Predicted GO
CC	GO:0009521	photosystem	IEP	Predicted GO
CC	GO:0009522	photosystem I	IEP	Predicted GO
CC	GO:0009523	photosystem II	IEP	Predicted GO
CC	GO:0009654	photosystem II oxygen evolving complex	IEP	Predicted GO
BP	GO:0010109	regulation of photosynthesis	IEP	Predicted GO
BP	GO:0010207	photosystem II assembly	IEP	Predicted GO
MF	GO:0010242	oxygen evolving activity	IEP	Predicted GO
BP	GO:0015979	photosynthesis	IEP	Predicted GO
BP	GO:0016043	cellular component organization	IEP	Predicted GO
MF	GO:0016209	antioxidant activity	IEP	Predicted GO
MF	GO:0016491	oxidoreductase activity	IEP	Predicted GO
MF	GO:0016651	oxidoreductase activity, acting on NAD(P)H	IEP	Predicted GO
MF	GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	IEP	Predicted GO
MF	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors	IEP	Predicted GO
MF	GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	IEP	Predicted GO
MF	GO:0016851	magnesium chelatase activity	IEP	Predicted GO
BP	GO:0019220	regulation of phosphate metabolic process	IEP	Predicted GO
BP	GO:0019222	regulation of metabolic process	IEP	Predicted GO
CC	GO:0019898	extrinsic component of membrane	IEP	Predicted GO
MF	GO:0019899	enzyme binding	IEP	Predicted GO
MF	GO:0019900	kinase binding	IEP	Predicted GO
MF	GO:0019901	protein kinase binding	IEP	Predicted GO
MF	GO:0020037	heme binding	IEP	Predicted GO
BP	GO:0022607	cellular component assembly	IEP	Predicted GO
CC	GO:0030076	light-harvesting complex	IEP	Predicted GO
CC	GO:0030089	phycobilisome	IEP	Predicted GO
BP	GO:0031323	regulation of cellular metabolic process	IEP	Predicted GO
BP	GO:0031399	regulation of protein modification process	IEP	Predicted GO
BP	GO:0032268	regulation of cellular protein metabolic process	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0034357	photosynthetic membrane	IEP	Predicted GO
BP	GO:0034622	cellular protein-containing complex assembly	IEP	Predicted GO
BP	GO:0042325	regulation of phosphorylation	IEP	Predicted GO
BP	GO:0042548	regulation of photosynthesis, light reaction	IEP	Predicted GO
BP	GO:0042549	photosystem II stabilization	IEP	Predicted GO
CC	GO:0042651	thylakoid membrane	IEP	Predicted GO
BP	GO:0043467	regulation of generation of precursor metabolites and energy	IEP	Predicted GO
BP	GO:0043549	regulation of kinase activity	IEP	Predicted GO
BP	GO:0043933	protein-containing complex subunit organization	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044425	membrane part	IEP	Predicted GO
CC	GO:0044436	thylakoid part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
BP	GO:0045859	regulation of protein kinase activity	IEP	Predicted GO
MF	GO:0046906	tetrapyrrole binding	IEP	Predicted GO
MF	GO:0048037	cofactor binding	IEP	Predicted GO
MF	GO:0050136	NADH dehydrogenase (quinone) activity	IEP	Predicted GO
BP	GO:0050790	regulation of catalytic activity	IEP	Predicted GO
MF	GO:0051002	ligase activity, forming nitrogen-metal bonds	IEP	Predicted GO
MF	GO:0051003	ligase activity, forming nitrogen-metal bonds, forming coordination complexes	IEP	Predicted GO
BP	GO:0051174	regulation of phosphorus metabolic process	IEP	Predicted GO
BP	GO:0051246	regulation of protein metabolic process	IEP	Predicted GO
BP	GO:0051338	regulation of transferase activity	IEP	Predicted GO
BP	GO:0051726	regulation of cell cycle	IEP	Predicted GO
MF	GO:0052880	oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor	IEP	Predicted GO
BP	GO:0055114	oxidation-reduction process	IEP	Predicted GO
BP	GO:0065003	protein-containing complex assembly	IEP	Predicted GO
BP	GO:0065009	regulation of molecular function	IEP	Predicted GO
BP	GO:0071840	cellular component organization or biogenesis	IEP	Predicted GO
BP	GO:0071900	regulation of protein serine/threonine kinase activity	IEP	Predicted GO
BP	GO:0072593	reactive oxygen species metabolic process	IEP	Predicted GO
CC	GO:0098796	membrane protein complex	IEP	Predicted GO
CC	GO:1902494	catalytic complex	IEP	Predicted GO
BP	GO:1904029	regulation of cyclin-dependent protein kinase activity	IEP	Predicted GO
CC	GO:1990204	oxidoreductase complex	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR001015	Ferrochelatase	107	410

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evm.model.tig00001388.13

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation