evm.model.tig00001600.10

Description : (p46225|tpic_secce : 277.0) Triosephosphate isomerase, chloroplast precursor (EC 5.3.1.1) (TIM) (Triose-phosphate isomerase) - Secale cereale (Rye) & (at2g21170 : 269.0) Encodes a plastidic triose phosphate isomerase. Mutants with reduced pdTPI levels have difficulty transitioning from heterotrophic to autotrophic growth. The related phenotypes, such as chlorosis in light-grown seedlings may result from an accumulation of dihydroxyacetone phosphate (DHAP) and methylglyoxal (MG) in these mutants. Both splice variants appear to be expressed, but the At2g21170.2 variant appears to have a much narrower expression range limited to roots.; triosephosphate isomerase (TIM); FUNCTIONS IN: triose-phosphate isomerase activity; INVOLVED IN: in 7 processes; LOCATED IN: thylakoid, mitochondrion, apoplast, chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Triosephosphate isomerase, active site (InterPro:IPR020861), Aldolase-type TIM barrel (InterPro:IPR013785), Triosephosphate isomerase (InterPro:IPR000652); BEST Arabidopsis thaliana protein match is: triosephosphate isomerase (TAIR:AT3G55440.1); Has 11527 Blast hits to 11525 proteins in 3623 species: Archae - 144; Bacteria - 6185; Metazoa - 1204; Fungi - 240; Plants - 472; Viruses - 0; Other Eukaryotes - 3282 (source: NCBI BLink). & (reliability: 538.0) & (original description: no original description)

Gene families : OG_42_0001246 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001246_tree

Sequence : coding (download), protein (download)

Download

Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00001600.10
Cluster	HCCA clusters: Cluster_22

Target	Alias	Description	ECC score	Gene Family Method
At2g21170	No alias	TIM [Source:UniProtKB/TrEMBL;Acc:A0A178VN28]	0.01	Orthogroups_2024-Update
Brara.D00398.1	No alias	cytosolic triose-phosphate isomerase & triose-phosphate...	0.01	Orthogroups_2024-Update
GRMZM2G018177	No alias	triosephosphate isomerase	0.02	Orthogroups_2024-Update
Glyma.15G038100	No alias	triosephosphate isomerase	0.03	Orthogroups_2024-Update
Kfl00094_0250	kfl00094_0250_v1.1	(at3g55440 : 379.0) Encodes triosephosphate isomerase.;...	0.02	Orthogroups_2024-Update
PSME_00021368-RA	No alias	(at2g21170 : 197.0) Encodes a plastidic triose phosphate...	0.02	Orthogroups_2024-Update
PSME_00032652-RA	No alias	(at2g21170 : 199.0) Encodes a plastidic triose phosphate...	0.02	Orthogroups_2024-Update
Potri.004G168000	No alias	triosephosphate isomerase	0.02	Orthogroups_2024-Update
Potri.008G056300	No alias	triosephosphate isomerase	0.02	Orthogroups_2024-Update
Pp1s3_334V6	No alias	triosephosphate isomerase	0.02	Orthogroups_2024-Update
Seita.5G377200.1	No alias	cytosolic triose-phosphate isomerase & triose-phosphate...	0.02	Orthogroups_2024-Update
Sopen01g053180	No alias	Triosephosphate isomerase	0.02	Orthogroups_2024-Update
Sopen06g001470	No alias	Triosephosphate isomerase	0.01	Orthogroups_2024-Update
Sopen10g024790	No alias	Triosephosphate isomerase	0.02	Orthogroups_2024-Update
evm.model.contig_2306.3	No alias	(p46225\|tpic_secce : 302.0) Triosephosphate isomerase,...	0.03	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004807	triose-phosphate isomerase activity	IEA	InterProScan predictions
MF	GO:0016853	isomerase activity	None	Extended
MF	GO:0016860	intramolecular oxidoreductase activity	None	Extended
MF	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	None	Extended

Toggle parental

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003676	nucleic acid binding	IEP	Predicted GO
MF	GO:0003678	DNA helicase activity	IEP	Predicted GO
MF	GO:0004175	endopeptidase activity	IEP	Predicted GO
MF	GO:0004298	threonine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004618	phosphoglycerate kinase activity	IEP	Predicted GO
MF	GO:0005488	binding	IEP	Predicted GO
MF	GO:0005509	calcium ion binding	IEP	Predicted GO
MF	GO:0005524	ATP binding	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005575	cellular_component	IEP	Predicted GO
CC	GO:0005789	endoplasmic reticulum membrane	IEP	Predicted GO
CC	GO:0005839	proteasome core complex	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006511	ubiquitin-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0008144	drug binding	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
BP	GO:0008380	RNA splicing	IEP	Predicted GO
BP	GO:0009056	catabolic process	IEP	Predicted GO
BP	GO:0009057	macromolecule catabolic process	IEP	Predicted GO
MF	GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IEP	Predicted GO
MF	GO:0016774	phosphotransferase activity, carboxyl group as acceptor	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	IEP	Predicted GO
MF	GO:0017076	purine nucleotide binding	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
CC	GO:0019773	proteasome core complex, alpha-subunit complex	IEP	Predicted GO
BP	GO:0019941	modification-dependent protein catabolic process	IEP	Predicted GO
MF	GO:0030554	adenyl nucleotide binding	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032553	ribonucleotide binding	IEP	Predicted GO
MF	GO:0032555	purine ribonucleotide binding	IEP	Predicted GO
MF	GO:0032559	adenyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
CC	GO:0032991	protein-containing complex	IEP	Predicted GO
CC	GO:0035145	exon-exon junction complex	IEP	Predicted GO
MF	GO:0035639	purine ribonucleoside triphosphate binding	IEP	Predicted GO
MF	GO:0036094	small molecule binding	IEP	Predicted GO
MF	GO:0043167	ion binding	IEP	Predicted GO
MF	GO:0043168	anion binding	IEP	Predicted GO
BP	GO:0043632	modification-dependent macromolecule catabolic process	IEP	Predicted GO
BP	GO:0044248	cellular catabolic process	IEP	Predicted GO
BP	GO:0044265	cellular macromolecule catabolic process	IEP	Predicted GO
CC	GO:0044424	intracellular part	IEP	Predicted GO
CC	GO:0044464	cell part	IEP	Predicted GO
MF	GO:0050662	coenzyme binding	IEP	Predicted GO
BP	GO:0051603	proteolysis involved in cellular protein catabolic process	IEP	Predicted GO
MF	GO:0070003	threonine-type peptidase activity	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
MF	GO:0097159	organic cyclic compound binding	IEP	Predicted GO
MF	GO:0097367	carbohydrate derivative binding	IEP	Predicted GO
MF	GO:1901265	nucleoside phosphate binding	IEP	Predicted GO
MF	GO:1901363	heterocyclic compound binding	IEP	Predicted GO
BP	GO:1901575	organic substance catabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000652	Triosephosphate_isomerase	18	227

External Links

No external refs found!

evm.model.tig00001600.10

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation