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  5. evm.model.tig00020537.14

evm.model.tig00020537.14


Description : (at1g04020 : 90.1) Encodes a protein containing two tandem BRCA1 C-Terminal (BRCT) domains, which function in phosphorylation-dependent proteinñprotein interactions.Loss of function mutations cause defects in meristem organization due to failure to repress WUS. BARD1 binds to WUS promoter and over expression of BARD reduces the extent of WUS expression.; breast cancer associated RING 1 (BARD1); FUNCTIONS IN: transcription coactivator activity, DNA binding; INVOLVED IN: DNA repair, regulation of meristem structural organization, leaf development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer susceptibility1 (TAIR:AT4G21070.1); Has 6045 Blast hits to 5706 proteins in 320 species: Archae - 0; Bacteria - 47; Metazoa - 4577; Fungi - 362; Plants - 542; Viruses - 11; Other Eukaryotes - 506 (source: NCBI BLink). & (reliability: 180.2) & (original description: no original description)


Gene families : OG_42_0000927 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000927_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00020537.14
Cluster HCCA clusters: Cluster_114

Target Alias Description ECC score Gene Family Method Actions
At1g04020 No alias Breast cancer associated RING 1... 0.01 Orthogroups_2024-Update
Cre07.g334650 No alias breast cancer susceptibility1 0.06 Orthogroups_2024-Update
Glyma.15G092000 No alias breast cancer susceptibility1 0.02 Orthogroups_2024-Update
Kfl00116_0090 kfl00116_0090_v1.... (at1g04020 : 184.0) Encodes a protein containing two... 0.08 Orthogroups_2024-Update
MA_187851g0010 No alias (at4g21070 : 105.0) Encodes AtBRCA1, an ortholog of the... 0.01 Orthogroups_2024-Update
PSME_00014683-RA No alias (at1g04020 : 160.0) Encodes a protein containing two... 0.01 Orthogroups_2024-Update
PSME_00045597-RA No alias (at4g21070 : 127.0) Encodes AtBRCA1, an ortholog of the... 0.01 Orthogroups_2024-Update
Solyc06g008210 No alias breast cancer associated RING 1 (AHRD V3.3 *** AT1G04020.1) 0.05 Orthogroups_2024-Update
Solyc08g023280 No alias RING/U-box superfamily protein (AHRD V3.3 --* AT3G07200.3) 0.02 Orthogroups_2024-Update
Sopen06g003070 No alias BRCA1 C Terminus (BRCT) domain 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
CC GO:0000151 ubiquitin ligase complex IEP Predicted GO
CC GO:0000152 nuclear ubiquitin ligase complex IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003690 double-stranded DNA binding IEP Predicted GO
MF GO:0003887 DNA-directed DNA polymerase activity IEP Predicted GO
MF GO:0003896 DNA primase activity IEP Predicted GO
MF GO:0003909 DNA ligase activity IEP Predicted GO
MF GO:0003910 DNA ligase (ATP) activity IEP Predicted GO
MF GO:0004003 ATP-dependent DNA helicase activity IEP Predicted GO
MF GO:0004797 thymidine kinase activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005680 anaphase-promoting complex IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006220 pyrimidine nucleotide metabolic process IEP Predicted GO
BP GO:0006221 pyrimidine nucleotide biosynthetic process IEP Predicted GO
BP GO:0006231 dTMP biosynthetic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
BP GO:0006333 chromatin assembly or disassembly IEP Predicted GO
BP GO:0006515 protein quality control for misfolded or incompletely synthesized proteins IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
MF GO:0008026 ATP-dependent helicase activity IEP Predicted GO
BP GO:0008156 negative regulation of DNA replication IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009129 pyrimidine nucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009157 deoxyribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009162 deoxyribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process IEP Predicted GO
BP GO:0009177 pyrimidine deoxyribonucleoside monophosphate biosynthetic process IEP Predicted GO
BP GO:0009219 pyrimidine deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009221 pyrimidine deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009262 deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009263 deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009265 2'-deoxyribonucleotide biosynthetic process IEP Predicted GO
BP GO:0009394 2'-deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009890 negative regulation of biosynthetic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010498 proteasomal protein catabolic process IEP Predicted GO
BP GO:0010558 negative regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0010605 negative regulation of macromolecule metabolic process IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0019136 deoxynucleoside kinase activity IEP Predicted GO
MF GO:0019205 nucleobase-containing compound kinase activity IEP Predicted GO
MF GO:0019206 nucleoside kinase activity IEP Predicted GO
BP GO:0019692 deoxyribose phosphate metabolic process IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
BP GO:0031144 proteasome localization IEP Predicted GO
BP GO:0031324 negative regulation of cellular metabolic process IEP Predicted GO
BP GO:0031327 negative regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031461 cullin-RING ubiquitin ligase complex IEP Predicted GO
BP GO:0031503 protein-containing complex localization IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
MF GO:0034061 DNA polymerase activity IEP Predicted GO
BP GO:0034629 cellular protein-containing complex localization IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity IEP Predicted GO
MF GO:0043015 gamma-tubulin binding IEP Predicted GO
MF GO:0043138 3'-5' DNA helicase activity IEP Predicted GO
MF GO:0043140 ATP-dependent 3'-5' DNA helicase activity IEP Predicted GO
BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
BP GO:0045005 DNA-dependent DNA replication maintenance of fidelity IEP Predicted GO
BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0046073 dTMP metabolic process IEP Predicted GO
BP GO:0046385 deoxyribose phosphate biosynthetic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0048478 replication fork protection IEP Predicted GO
MF GO:0050797 thymidylate synthase (FAD) activity IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051052 regulation of DNA metabolic process IEP Predicted GO
BP GO:0051053 negative regulation of DNA metabolic process IEP Predicted GO
BP GO:0051172 negative regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
MF GO:0070035 purine NTP-dependent helicase activity IEP Predicted GO
BP GO:0071630 nuclear protein quality control by the ubiquitin-proteasome system IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0072527 pyrimidine-containing compound metabolic process IEP Predicted GO
BP GO:0072528 pyrimidine-containing compound biosynthetic process IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090329 regulation of DNA-dependent DNA replication IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901565 organonitrogen compound catabolic process IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:2000104 negative regulation of DNA-dependent DNA replication IEP Predicted GO
BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process IEP Predicted GO

No InterPro domains available for this sequence

No external refs found!