evm.model.tig00020553.190

Description : (at2g47800 : 157.0) Encodes a plasma membrane localized ATPase transporter involved in multidrug transport. The expression of this gene is upregulated by herbicide safeners such as benoxacor, fluxofenim and fenclorim.; multidrug resistance-associated protein 4 (MRP4); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances, folic acid transporter activity; INVOLVED IN: response to water deprivation, drug transmembrane transport, response to wounding, response to nematode, stomatal movement; LOCATED IN: vacuolar membrane, plasma membrane, vacuole, plant-type vacuole; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 10 (TAIR:AT3G62700.1); Has 714857 Blast hits to 368077 proteins in 3991 species: Archae - 12925; Bacteria - 579268; Metazoa - 12980; Fungi - 8565; Plants - 6599; Viruses - 19; Other Eukaryotes - 94501 (source: NCBI BLink). & (q6yuu5|mdr_orysa : 93.6) Putative multidrug resistance protein (P-glycoprotein) - Oryza sativa (Rice) & (reliability: 314.0) & (original description: no original description)

Gene families : OG_42_0000076 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000076_tree

Sequence : coding (download), protein (download)

Attention: This gene has low abundance.

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Cyanophora release: evm.model.tig00020553.190
Cluster	HCCA clusters: Cluster_117

Target	Alias	Description	ECC score	Gene Family Method
145432	No alias	multidrug resistance-associated protein 6	0.01	Orthogroups_2024-Update
169678	No alias	multidrug resistance-associated protein 6	0.01	Orthogroups_2024-Update
Bradi2g04577	No alias	multidrug resistance-associated protein 3	0.01	Orthogroups_2024-Update
Bradi5g03460	No alias	multidrug resistance-associated protein 10	0.01	Orthogroups_2024-Update
Cre13.g564900	No alias	multidrug resistance-associated protein 2	0.02	Orthogroups_2024-Update
Cre17.g734612	No alias	multidrug resistance-associated protein 2	0.03	Orthogroups_2024-Update
Glyma.08G194600	No alias	multidrug resistance-associated protein 6	0.02	Orthogroups_2024-Update
Glyma.13G220000	No alias	multidrug resistance-associated protein 2	0.02	Orthogroups_2024-Update
HORVU7Hr1G024960.12	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
HORVU7Hr1G024980.9	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
HORVU7Hr1G088210.25	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
Kfl00085_0340	kfl00085_0340_v1.1	(at2g34660 : 585.0) encodes a multidrug...	0.03	Orthogroups_2024-Update
Kfl00342_0130	kfl00342_0130_v1.1	(at1g30420 : 405.0) member of MRP subfamily; multidrug...	0.03	Orthogroups_2024-Update
Mp4g11930.1	No alias	subfamily ABCC transporter	0.02	Orthogroups_2024-Update
Mp5g02230.1	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
Mp5g13190.1	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update
Pp1s342_31V6	No alias	multidrug resistance protein abc transporter family	0.01	Orthogroups_2024-Update
Sobic.007G210500.2	No alias	subfamily ABCC transporter	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015399	primary active transmembrane transporter activity	None	Extended
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	None	Extended
CC	GO:0016021	integral component of membrane	IEA	InterProScan predictions
MF	GO:0016462	pyrophosphatase activity	None	Extended
MF	GO:0016787	hydrolase activity	None	Extended
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	None	Extended
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	None	Extended
MF	GO:0016887	ATPase activity	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0017111	nucleoside-triphosphatase activity	None	Extended
MF	GO:0022804	active transmembrane transporter activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
CC	GO:0031224	intrinsic component of membrane	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0042623	ATPase activity, coupled	None	Extended
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA	InterProScan predictions
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0043492	ATPase activity, coupled to movement of substances	None	Extended
CC	GO:0044425	membrane part	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004089	carbonate dehydratase activity	IEP	Predicted GO
BP	GO:0006855	drug transmembrane transport	IEP	Predicted GO
BP	GO:0009119	ribonucleoside metabolic process	IEP	Predicted GO
MF	GO:0015238	drug transmembrane transporter activity	IEP	Predicted GO
BP	GO:0015893	drug transport	IEP	Predicted GO
BP	GO:0015969	guanosine tetraphosphate metabolic process	IEP	Predicted GO
CC	GO:0016020	membrane	IEP	Predicted GO
BP	GO:0016226	iron-sulfur cluster assembly	IEP	Predicted GO
CC	GO:0031090	organelle membrane	IEP	Predicted GO
BP	GO:0031163	metallo-sulfur cluster assembly	IEP	Predicted GO
CC	GO:0031966	mitochondrial membrane	IEP	Predicted GO
BP	GO:0033865	nucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0033875	ribonucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0034032	purine nucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0034035	purine ribonucleoside bisphosphate metabolic process	IEP	Predicted GO
BP	GO:0042278	purine nucleoside metabolic process	IEP	Predicted GO
BP	GO:0046128	purine ribonucleoside metabolic process	IEP	Predicted GO
MF	GO:0071949	FAD binding	IEP	Predicted GO
BP	GO:1901068	guanosine-containing compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003439	ABC_transporter-like	782	845
IPR011527	ABC1_TM_dom	374	609
IPR003439	ABC_transporter-like	71	107

External Links

No external refs found!

evm.model.tig00020553.190

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation