evm.model.tig00020780.46


Description : (at1g04980 : 93.2) Encodes a protein disulfide isomerase-like (PDIL) protein, a member of a multigene family within the thioredoxin (TRX) superfamily. Transcript levels for this gene are up-regulated in response to three different chemical inducers of ER stress (dithiothreitol, beta-mercaptoethanol, and tunicamycin). AtIRE1-2 does not appear to be required for this response, but the atbzip60 mutant has a diminished response.; PDI-like 2-2 (PDIL2-2); CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Disulphide isomerase (InterPro:IPR005788), Thioredoxin domain (InterPro:IPR013766), Thioredoxin, conserved site (InterPro:IPR017937), Thioredoxin-like subdomain (InterPro:IPR006662), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: PDI-like 2-3 (TAIR:AT2G32920.1); Has 36254 Blast hits to 18629 proteins in 2906 species: Archae - 392; Bacteria - 18066; Metazoa - 5792; Fungi - 2053; Plants - 2624; Viruses - 46; Other Eukaryotes - 7281 (source: NCBI BLink). & (p52589|pdi_wheat : 87.4) Protein disulfide-isomerase precursor (EC 5.3.4.1) (PDI) - Triticum aestivum (Wheat) & (reliability: 186.4) & (original description: no original description)


Gene families : OG_42_0006531 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006531_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00020780.46
Cluster HCCA clusters: Cluster_67

Target Alias Description ECC score Gene Family Method Actions
Bradi1g65710 No alias PDI-like 5-1 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0045454 cell redox homeostasis IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004857 enzyme inhibitor activity IEP Predicted GO
MF GO:0004864 protein phosphatase inhibitor activity IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0010921 regulation of phosphatase activity IEP Predicted GO
MF GO:0019208 phosphatase regulator activity IEP Predicted GO
MF GO:0019212 phosphatase inhibitor activity IEP Predicted GO
BP GO:0019220 regulation of phosphate metabolic process IEP Predicted GO
MF GO:0019888 protein phosphatase regulator activity IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
MF GO:0030234 enzyme regulator activity IEP Predicted GO
BP GO:0031399 regulation of protein modification process IEP Predicted GO
BP GO:0032268 regulation of cellular protein metabolic process IEP Predicted GO
BP GO:0035303 regulation of dephosphorylation IEP Predicted GO
BP GO:0035304 regulation of protein dephosphorylation IEP Predicted GO
BP GO:0043666 regulation of phosphoprotein phosphatase activity IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
BP GO:0050790 regulation of catalytic activity IEP Predicted GO
BP GO:0051174 regulation of phosphorus metabolic process IEP Predicted GO
BP GO:0051246 regulation of protein metabolic process IEP Predicted GO
BP GO:0051336 regulation of hydrolase activity IEP Predicted GO
BP GO:0065009 regulation of molecular function IEP Predicted GO
InterPro domains Description Start Stop
IPR013766 Thioredoxin_domain 43 142
No external refs found!