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  5. evm.model.tig00021119.6

evm.model.tig00021119.6


Description : (at1g48050 : 99.8) Ku80 and ku70 form the heterodimer complex Ku, required for proper maintenance of the telomeric C strand. Ku regulates the extension of the telomeric G strand. Interacts with WEX, and this interaction stimulates the WEX exonuclease activity. Binds double stranded DNA breaks as a heterodimer with Ku70, involved in non-homologous end joining repair. Mutants are defective in T-DNA integration. Over expression confers increased resistance to DNA damage agents and increased susceptibility to T-DNA transformation.; KU80; FUNCTIONS IN: double-stranded DNA binding, protein binding; INVOLVED IN: in 6 processes; LOCATED IN: nucleus; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ku70/Ku80, N-terminal alpha/beta (InterPro:IPR005161), DNA helicase, ATP-dependent, Ku type (InterPro:IPR006164), Spen Paralogue and Orthologue SPOC, C-terminal-like (InterPro:IPR016194), Ku70/Ku80 C-terminal arm (InterPro:IPR005160), Ku, C-terminal (InterPro:IPR014893); Has 786 Blast hits to 750 proteins in 217 species: Archae - 0; Bacteria - 40; Metazoa - 246; Fungi - 345; Plants - 62; Viruses - 0; Other Eukaryotes - 93 (source: NCBI BLink). & (reliability: 199.6) & (original description: no original description)


Gene families : OG_42_0001893 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001893_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00021119.6
Cluster HCCA clusters: Cluster_102

Target Alias Description ECC score Gene Family Method Actions
PSME_00007329-RA No alias no hits & (original description: no original description) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003684 damaged DNA binding IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0005227 calcium activated cation channel activity IEP Predicted GO
MF GO:0005261 cation channel activity IEP Predicted GO
MF GO:0005267 potassium channel activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
MF GO:0005543 phospholipid binding IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
BP GO:0006325 chromatin organization IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006479 protein methylation IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006812 cation transport IEP Predicted GO
BP GO:0006813 potassium ion transport IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
MF GO:0008170 N-methyltransferase activity IEP Predicted GO
BP GO:0008213 protein alkylation IEP Predicted GO
MF GO:0008276 protein methyltransferase activity IEP Predicted GO
MF GO:0008289 lipid binding IEP Predicted GO
MF GO:0008324 cation transmembrane transporter activity IEP Predicted GO
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Predicted GO
MF GO:0015077 monovalent inorganic cation transmembrane transporter activity IEP Predicted GO
MF GO:0015079 potassium ion transmembrane transporter activity IEP Predicted GO
MF GO:0015269 calcium-activated potassium channel activity IEP Predicted GO
BP GO:0015672 monovalent inorganic cation transport IEP Predicted GO
BP GO:0015985 energy coupled proton transport, down electrochemical gradient IEP Predicted GO
BP GO:0015986 ATP synthesis coupled proton transport IEP Predicted GO
MF GO:0016278 lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016286 small conductance calcium-activated potassium channel activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
BP GO:0016569 covalent chromatin modification IEP Predicted GO
BP GO:0016570 histone modification IEP Predicted GO
BP GO:0016571 histone methylation IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018022 peptidyl-lysine methylation IEP Predicted GO
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0018205 peptidyl-lysine modification IEP Predicted GO
BP GO:0019538 protein metabolic process IEP Predicted GO
MF GO:0019829 cation-transporting ATPase activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
MF GO:0022853 active ion transmembrane transporter activity IEP Predicted GO
MF GO:0022890 inorganic cation transmembrane transporter activity IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
BP GO:0032259 methylation IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
CC GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain IEP Predicted GO
BP GO:0034968 histone lysine methylation IEP Predicted GO
MF GO:0035091 phosphatidylinositol binding IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
MF GO:0042054 histone methyltransferase activity IEP Predicted GO
MF GO:0042625 ATPase coupled ion transmembrane transporter activity IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
BP GO:0043414 macromolecule methylation IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
BP GO:0044267 cellular protein metabolic process IEP Predicted GO
MF GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism IEP Predicted GO
CC GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1) IEP Predicted GO
MF GO:0046933 proton-transporting ATP synthase activity, rotational mechanism IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901564 organonitrogen compound metabolic process IEP Predicted GO
BP GO:1902600 proton transmembrane transport IEP Predicted GO
InterPro domains Description Start Stop
IPR014893 Ku_PK_bind 681 785
IPR005161 Ku_N 31 183
No external refs found!