Description : (at2g20000 : 287.0) Required for cell division and cell differentiation in meristems. Encodes a homolog of the CDC27 subunit of the anaphase-promoting complex (APC). Unlike other CDC27 homologs in Arabidopsis, its transcription is cell cycle regulated. Strong hbt mutants give rise to seedlings that lack an anatomically recognizable quiescent center and differentiated columella root cap cells, the cell types derived from the wild-type hypophysis. Furthermore, they have no mitotically active root meristem and lack a differentiated lateral root cap.; HOBBIT (HBT); FUNCTIONS IN: binding; INVOLVED IN: in 10 processes; LOCATED IN: anaphase-promoting complex, nucleus, cell plate, spindle; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Tetratricopeptide TPR-1 (InterPro:IPR001440), Tetratricopeptide-like helical (InterPro:IPR011990), Tetratricopeptide repeat-containing (InterPro:IPR013026), Tetratricopeptide repeat (InterPro:IPR019734); BEST Arabidopsis thaliana protein match is: Tetratricopeptide repeat (TPR)-like superfamily protein (TAIR:AT3G16320.1); Has 19127 Blast hits to 10740 proteins in 1344 species: Archae - 1126; Bacteria - 9300; Metazoa - 1888; Fungi - 782; Plants - 572; Viruses - 0; Other Eukaryotes - 5459 (source: NCBI BLink). & (reliability: 574.0) & (original description: no original description)
Gene families : OG_42_0004978 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004978_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00021348.12 | |
Cluster | HCCA clusters: Cluster_168 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Brara.G00104.1 | No alias | component *(APC3) of (APC/C)-dependent ubiquitination... | 0.01 | Orthogroups_2024-Update | |
Cre17.g740510 | No alias | Tetratricopeptide repeat (TPR)-like superfamily protein | 0.04 | Orthogroups_2024-Update | |
Solyc03g061590 | No alias | Cell division cycle protein 27 homolog B (AHRD V3.3 *-*... | 0.01 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0005515 | protein binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
CC | GO:0000151 | ubiquitin ligase complex | IEP | Predicted GO |
CC | GO:0000152 | nuclear ubiquitin ligase complex | IEP | Predicted GO |
MF | GO:0003924 | GTPase activity | IEP | Predicted GO |
MF | GO:0004003 | ATP-dependent DNA helicase activity | IEP | Predicted GO |
CC | GO:0005634 | nucleus | IEP | Predicted GO |
CC | GO:0005680 | anaphase-promoting complex | IEP | Predicted GO |
BP | GO:0006259 | DNA metabolic process | IEP | Predicted GO |
BP | GO:0006260 | DNA replication | IEP | Predicted GO |
BP | GO:0006281 | DNA repair | IEP | Predicted GO |
BP | GO:0006950 | response to stress | IEP | Predicted GO |
BP | GO:0006974 | cellular response to DNA damage stimulus | IEP | Predicted GO |
MF | GO:0008017 | microtubule binding | IEP | Predicted GO |
MF | GO:0008026 | ATP-dependent helicase activity | IEP | Predicted GO |
MF | GO:0008092 | cytoskeletal protein binding | IEP | Predicted GO |
MF | GO:0010277 | chlorophyllide a oxygenase [overall] activity | IEP | Predicted GO |
MF | GO:0015631 | tubulin binding | IEP | Predicted GO |
MF | GO:0016703 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases) | IEP | Predicted GO |
CC | GO:0031461 | cullin-RING ubiquitin ligase complex | IEP | Predicted GO |
BP | GO:0033554 | cellular response to stress | IEP | Predicted GO |
MF | GO:0043015 | gamma-tubulin binding | IEP | Predicted GO |
MF | GO:0043138 | 3'-5' DNA helicase activity | IEP | Predicted GO |
MF | GO:0043140 | ATP-dependent 3'-5' DNA helicase activity | IEP | Predicted GO |
BP | GO:0050896 | response to stimulus | IEP | Predicted GO |
BP | GO:0051716 | cellular response to stimulus | IEP | Predicted GO |
MF | GO:0070035 | purine NTP-dependent helicase activity | IEP | Predicted GO |
MF | GO:0140097 | catalytic activity, acting on DNA | IEP | Predicted GO |
No external refs found! |