Description : (at3g01120 : 447.0) encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.; METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink). & (reliability: 894.0) & (original description: no original description)
Gene families : OG_42_0001443 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001443_tree
Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.
Type | Description | Actions |
---|---|---|
Neighborhood | Cyanophora release: evm.model.tig00021350.37 | |
Cluster | HCCA clusters: Cluster_154 |
Target | Alias | Description | ECC score | Gene Family Method | Actions |
---|---|---|---|---|---|
Brara.E03611.1 | No alias | cystathionine gamma-synthase & EC_2.5 transferase... | 0.02 | Orthogroups_2024-Update | |
LOC_Os06g07860 | No alias | cystathionine gamma-synthase, putative, expressed | 0.02 | Orthogroups_2024-Update | |
Seita.4G055800.1 | No alias | cystathionine beta-lyase & EC_4.4 carbon-sulfur lyase &... | 0.02 | Orthogroups_2024-Update | |
Seita.9G255100.1 | No alias | cystathionine gamma-synthase & EC_2.5 transferase... | 0.02 | Orthogroups_2024-Update | |
Seita.9G255300.1 | No alias | cystathionine gamma-synthase & EC_2.5 transferase... | 0.02 | Orthogroups_2024-Update | |
Solyc10g079720 | No alias | Cystathionine beta-lyase | 0.02 | Orthogroups_2024-Update | |
evm.model.contig_4509.2 | No alias | (at3g01120 : 171.0) encodes a cystathionine... | 0.02 | Orthogroups_2024-Update |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0030170 | pyridoxal phosphate binding | IEA | InterProScan predictions |
Type | GO Term | Name | Evidence | Source |
---|---|---|---|---|
MF | GO:0004672 | protein kinase activity | IEP | Predicted GO |
CC | GO:0005956 | protein kinase CK2 complex | IEP | Predicted GO |
BP | GO:0006355 | regulation of transcription, DNA-templated | IEP | Predicted GO |
BP | GO:0006464 | cellular protein modification process | IEP | Predicted GO |
BP | GO:0006468 | protein phosphorylation | IEP | Predicted GO |
BP | GO:0009889 | regulation of biosynthetic process | IEP | Predicted GO |
BP | GO:0010468 | regulation of gene expression | IEP | Predicted GO |
BP | GO:0010556 | regulation of macromolecule biosynthetic process | IEP | Predicted GO |
MF | GO:0016301 | kinase activity | IEP | Predicted GO |
BP | GO:0016310 | phosphorylation | IEP | Predicted GO |
MF | GO:0016773 | phosphotransferase activity, alcohol group as acceptor | IEP | Predicted GO |
MF | GO:0019207 | kinase regulator activity | IEP | Predicted GO |
BP | GO:0019219 | regulation of nucleobase-containing compound metabolic process | IEP | Predicted GO |
BP | GO:0019222 | regulation of metabolic process | IEP | Predicted GO |
MF | GO:0019887 | protein kinase regulator activity | IEP | Predicted GO |
BP | GO:0031323 | regulation of cellular metabolic process | IEP | Predicted GO |
BP | GO:0031326 | regulation of cellular biosynthetic process | IEP | Predicted GO |
BP | GO:0034622 | cellular protein-containing complex assembly | IEP | Predicted GO |
BP | GO:0036211 | protein modification process | IEP | Predicted GO |
BP | GO:0043412 | macromolecule modification | IEP | Predicted GO |
MF | GO:0043565 | sequence-specific DNA binding | IEP | Predicted GO |
BP | GO:0051171 | regulation of nitrogen compound metabolic process | IEP | Predicted GO |
BP | GO:0051252 | regulation of RNA metabolic process | IEP | Predicted GO |
BP | GO:0060255 | regulation of macromolecule metabolic process | IEP | Predicted GO |
BP | GO:0070070 | proton-transporting V-type ATPase complex assembly | IEP | Predicted GO |
BP | GO:0070071 | proton-transporting two-sector ATPase complex assembly | IEP | Predicted GO |
BP | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly | IEP | Predicted GO |
BP | GO:0080090 | regulation of primary metabolic process | IEP | Predicted GO |
BP | GO:1903506 | regulation of nucleic acid-templated transcription | IEP | Predicted GO |
BP | GO:2000112 | regulation of cellular macromolecule biosynthetic process | IEP | Predicted GO |
BP | GO:2001141 | regulation of RNA biosynthetic process | IEP | Predicted GO |
InterPro domains | Description | Start | Stop |
---|---|---|---|
IPR000277 | Cys/Met-Metab_PyrdxlP-dep_enz | 126 | 511 |
No external refs found! |