evm.model.tig00021350.37


Description : (at3g01120 : 447.0) encodes a cystathionine gamma-synthase, which performs the first committed step in methionine biosynthesis. A conserved motif of 13 amino acids in the first exon is required for posttranscriptional autoregulation. This enzyme shares the same substrate as threonine synthase (TS) and its absence transcriptionally affects 8 genes in the genome.; METHIONINE OVERACCUMULATION 1 (MTO1); FUNCTIONS IN: cystathionine gamma-synthase activity; INVOLVED IN: methionine biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Cys/Met metabolism, pyridoxal phosphate-dependent enzyme (InterPro:IPR000277), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422); BEST Arabidopsis thaliana protein match is: Pyridoxal phosphate (PLP)-dependent transferases superfamily protein (TAIR:AT1G33320.1); Has 21364 Blast hits to 20702 proteins in 2452 species: Archae - 220; Bacteria - 11705; Metazoa - 241; Fungi - 842; Plants - 284; Viruses - 13; Other Eukaryotes - 8059 (source: NCBI BLink). & (reliability: 894.0) & (original description: no original description)


Gene families : OG_42_0001443 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001443_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Cyanophora release: evm.model.tig00021350.37
Cluster HCCA clusters: Cluster_154

Target Alias Description ECC score Gene Family Method Actions
Brara.E03611.1 No alias cystathionine gamma-synthase & EC_2.5 transferase... 0.02 Orthogroups_2024-Update
LOC_Os06g07860 No alias cystathionine gamma-synthase, putative, expressed 0.02 Orthogroups_2024-Update
Seita.4G055800.1 No alias cystathionine beta-lyase & EC_4.4 carbon-sulfur lyase &... 0.02 Orthogroups_2024-Update
Seita.9G255100.1 No alias cystathionine gamma-synthase & EC_2.5 transferase... 0.02 Orthogroups_2024-Update
Seita.9G255300.1 No alias cystathionine gamma-synthase & EC_2.5 transferase... 0.02 Orthogroups_2024-Update
Solyc10g079720 No alias Cystathionine beta-lyase 0.02 Orthogroups_2024-Update
evm.model.contig_4509.2 No alias (at3g01120 : 171.0) encodes a cystathionine... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0030170 pyridoxal phosphate binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEP Predicted GO
CC GO:0005956 protein kinase CK2 complex IEP Predicted GO
BP GO:0006355 regulation of transcription, DNA-templated IEP Predicted GO
BP GO:0006464 cellular protein modification process IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0009889 regulation of biosynthetic process IEP Predicted GO
BP GO:0010468 regulation of gene expression IEP Predicted GO
BP GO:0010556 regulation of macromolecule biosynthetic process IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
BP GO:0016310 phosphorylation IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
BP GO:0019219 regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0019222 regulation of metabolic process IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
BP GO:0031323 regulation of cellular metabolic process IEP Predicted GO
BP GO:0031326 regulation of cellular biosynthetic process IEP Predicted GO
BP GO:0034622 cellular protein-containing complex assembly IEP Predicted GO
BP GO:0036211 protein modification process IEP Predicted GO
BP GO:0043412 macromolecule modification IEP Predicted GO
MF GO:0043565 sequence-specific DNA binding IEP Predicted GO
BP GO:0051171 regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051252 regulation of RNA metabolic process IEP Predicted GO
BP GO:0060255 regulation of macromolecule metabolic process IEP Predicted GO
BP GO:0070070 proton-transporting V-type ATPase complex assembly IEP Predicted GO
BP GO:0070071 proton-transporting two-sector ATPase complex assembly IEP Predicted GO
BP GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly IEP Predicted GO
BP GO:0080090 regulation of primary metabolic process IEP Predicted GO
BP GO:1903506 regulation of nucleic acid-templated transcription IEP Predicted GO
BP GO:2000112 regulation of cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:2001141 regulation of RNA biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR000277 Cys/Met-Metab_PyrdxlP-dep_enz 126 511
No external refs found!