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  5. Kfl00008_0090

Kfl00008_0090 (kfl00008_0090_v1.1)


Aliases : kfl00008_0090_v1.1

Description : (p31251|ube12_wheat : 1361.0) Ubiquitin-activating enzyme E1 2 - Triticum aestivum (Wheat) & (at5g06460 : 1321.0) Encodes a ubiquitin-activating enzyme (E1), involved in the first step in conjugating multiple ubiquitins to proteins targeted for degradation. Gene is expressed in most tissues examined.; ubiquitin activating enzyme 2 (UBA 2); FUNCTIONS IN: ubiquitin-protein ligase activity, ubiquitin activating enzyme activity; INVOLVED IN: protein ubiquitination, ubiquitin-dependent protein catabolic process; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ubiquitin-activating enzyme, E1, active site (InterPro:IPR018074), Ubiquitin-activating enzyme, E1 (InterPro:IPR018075), Ubiquitin-activating enzyme e1, C-terminal (InterPro:IPR018965), Ubiquitin-activating enzyme repeat (InterPro:IPR000127), Ubiquitin-activating enzyme (InterPro:IPR019572), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040), Ubiquitin-activating enzyme, E1-like (InterPro:IPR000011); BEST Arabidopsis thaliana protein match is: ubiquitin-activating enzyme 1 (TAIR:AT2G30110.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 2642.0) & (original description: no original description)


Gene families : OG_42_0001467 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001467_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00008_0090
Cluster HCCA clusters: Cluster_10

Target Alias Description ECC score Gene Family Method Actions
At2g30110 No alias UBA1 [Source:UniProtKB/TrEMBL;Acc:A0A178VN59] 0.02 Orthogroups_2024-Update
Bradi1g16680 No alias ubiquitin activating enzyme 2 0.02 Orthogroups_2024-Update
Brara.C01534.1 No alias E1 ubiquitin-activating enzyme 0.02 Orthogroups_2024-Update
Brara.E01311.1 No alias E1 ubiquitin-activating enzyme 0.04 Orthogroups_2024-Update
Cre09.g386400 No alias ubiquitin activating enzyme 2 0.03 Orthogroups_2024-Update
Glyma.02G229700 No alias ubiquitin activating enzyme 2 0.02 Orthogroups_2024-Update
Glyma.11G166100 No alias ubiquitin-activating enzyme 1 0.02 Orthogroups_2024-Update
HORVU4Hr1G024590.3 No alias E1 ubiquitin-activating enzyme 0.02 Orthogroups_2024-Update
HORVU5Hr1G047790.1 No alias E1 ubiquitin-activating enzyme 0.02 Orthogroups_2024-Update
MA_107903g0010 No alias (p31251|ube12_wheat : 1518.0) Ubiquitin-activating... 0.03 Orthogroups_2024-Update
Mp4g15300.1 No alias ubiquitin-activating E1 protein 0.03 Orthogroups_2024-Update
Mp7g08080.1 No alias ubiquitin-activating E1 protein 0.02 Orthogroups_2024-Update
PSME_00016707-RA No alias (p31251|ube12_wheat : 1493.0) Ubiquitin-activating... 0.03 Orthogroups_2024-Update
Pp1s5_305V6 No alias ubiquitin-activating enzyme 0.02 Orthogroups_2024-Update
Pp1s74_65V6 No alias ubiquitin-activating enzyme 0.02 Orthogroups_2024-Update
Seita.7G331900.1 No alias E1 ubiquitin-activating enzyme 0.04 Orthogroups_2024-Update
Seita.8G019500.1 No alias E1 ubiquitin-activating enzyme 0.04 Orthogroups_2024-Update
Sobic.005G004400.2 No alias E1 ubiquitin-activating enzyme 0.04 Orthogroups_2024-Update
evm.model.contig_2295.1 No alias (p20973|ube11_wheat : 743.0) Ubiquitin-activating enzyme... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0008641 ubiquitin-like modifier activating enzyme activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000097 sulfur amino acid biosynthetic process IEP Predicted GO
BP GO:0000271 polysaccharide biosynthetic process IEP Predicted GO
BP GO:0001505 regulation of neurotransmitter levels IEP Predicted GO
MF GO:0003873 6-phosphofructo-2-kinase activity IEP Predicted GO
MF GO:0004143 diacylglycerol kinase activity IEP Predicted GO
MF GO:0004181 metallocarboxypeptidase activity IEP Predicted GO
MF GO:0004375 glycine dehydrogenase (decarboxylating) activity IEP Predicted GO
MF GO:0004478 methionine adenosyltransferase activity IEP Predicted GO
MF GO:0004645 phosphorylase activity IEP Predicted GO
MF GO:0004843 thiol-dependent ubiquitin-specific protease activity IEP Predicted GO
MF GO:0005085 guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005086 ARF guanyl-nucleotide exchange factor activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0006000 fructose metabolic process IEP Predicted GO
BP GO:0006073 cellular glucan metabolic process IEP Predicted GO
BP GO:0006544 glycine metabolic process IEP Predicted GO
BP GO:0006546 glycine catabolic process IEP Predicted GO
BP GO:0006555 methionine metabolic process IEP Predicted GO
BP GO:0006556 S-adenosylmethionine biosynthetic process IEP Predicted GO
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006888 ER to Golgi vesicle-mediated transport IEP Predicted GO
BP GO:0007186 G protein-coupled receptor signaling pathway IEP Predicted GO
BP GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
MF GO:0008172 S-methyltransferase activity IEP Predicted GO
MF GO:0008184 glycogen phosphorylase activity IEP Predicted GO
MF GO:0008235 metalloexopeptidase activity IEP Predicted GO
MF GO:0008252 nucleotidase activity IEP Predicted GO
MF GO:0008253 5'-nucleotidase activity IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
MF GO:0008705 methionine synthase activity IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009063 cellular amino acid catabolic process IEP Predicted GO
BP GO:0009069 serine family amino acid metabolic process IEP Predicted GO
BP GO:0009071 serine family amino acid catabolic process IEP Predicted GO
BP GO:0009086 methionine biosynthetic process IEP Predicted GO
BP GO:0009250 glucan biosynthetic process IEP Predicted GO
BP GO:0009262 deoxyribonucleotide metabolic process IEP Predicted GO
BP GO:0009264 deoxyribonucleotide catabolic process IEP Predicted GO
BP GO:0009966 regulation of signal transduction IEP Predicted GO
MF GO:0010181 FMN binding IEP Predicted GO
BP GO:0010215 cellulose microfibril organization IEP Predicted GO
BP GO:0010646 regulation of cell communication IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
BP GO:0016049 cell growth IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016759 cellulose synthase activity IEP Predicted GO
MF GO:0016760 cellulose synthase (UDP-forming) activity IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
BP GO:0023051 regulation of signaling IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030118 clathrin coat IEP Predicted GO
CC GO:0030119 AP-type membrane coat adaptor complex IEP Predicted GO
CC GO:0030120 vesicle coat IEP Predicted GO
CC GO:0030125 clathrin vesicle coat IEP Predicted GO
CC GO:0030127 COPII vesicle coat IEP Predicted GO
CC GO:0030130 clathrin coat of trans-Golgi network vesicle IEP Predicted GO
CC GO:0030131 clathrin adaptor complex IEP Predicted GO
CC GO:0030132 clathrin coat of coated pit IEP Predicted GO
BP GO:0030198 extracellular matrix organization IEP Predicted GO
BP GO:0030243 cellulose metabolic process IEP Predicted GO
BP GO:0030244 cellulose biosynthetic process IEP Predicted GO
CC GO:0031225 anchored component of membrane IEP Predicted GO
MF GO:0031419 cobalamin binding IEP Predicted GO
MF GO:0031625 ubiquitin protein ligase binding IEP Predicted GO
BP GO:0032012 regulation of ARF protein signal transduction IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
BP GO:0033692 cellular polysaccharide biosynthetic process IEP Predicted GO
BP GO:0040007 growth IEP Predicted GO
MF GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity IEP Predicted GO
BP GO:0042133 neurotransmitter metabolic process IEP Predicted GO
BP GO:0042135 neurotransmitter catabolic process IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
BP GO:0042737 drug catabolic process IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0043062 extracellular structure organization IEP Predicted GO
BP GO:0044042 glucan metabolic process IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
BP GO:0044264 cellular polysaccharide metabolic process IEP Predicted GO
BP GO:0044272 sulfur compound biosynthetic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
MF GO:0044389 ubiquitin-like protein ligase binding IEP Predicted GO
CC GO:0044425 membrane part IEP Predicted GO
CC GO:0044433 cytoplasmic vesicle part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046500 S-adenosylmethionine metabolic process IEP Predicted GO
BP GO:0046578 regulation of Ras protein signal transduction IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0048193 Golgi vesicle transport IEP Predicted GO
BP GO:0048583 regulation of response to stimulus IEP Predicted GO
BP GO:0050789 regulation of biological process IEP Predicted GO
BP GO:0050794 regulation of cellular process IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051056 regulation of small GTPase mediated signal transduction IEP Predicted GO
BP GO:0051273 beta-glucan metabolic process IEP Predicted GO
BP GO:0051274 beta-glucan biosynthetic process IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0065007 biological regulation IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
MF GO:0098772 molecular function regulator IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901605 alpha-amino acid metabolic process IEP Predicted GO
BP GO:1901606 alpha-amino acid catabolic process IEP Predicted GO
BP GO:1902531 regulation of intracellular signal transduction IEP Predicted GO
InterPro domains Description Start Stop
IPR000594 ThiF_NAD_FAD-bd 441 939
IPR032420 E1_4HB 291 360
IPR019572 UBA_E1_Cys 628 880
IPR000594 ThiF_NAD_FAD-bd 46 419
IPR018965 Ub-activating_enz_E1_C 950 1041
IPR032418 E1_FCCH 219 289
No external refs found!