Kfl00009_0260 (kfl00009_0260_v1.1)


Aliases : kfl00009_0260_v1.1

Description : (at5g64813 : 168.0) The LIP1 gene encodes a small GTPase that influences the light input pathway of the plant circadian network. An MBP:LIP1 fusion protein has GTP hydrolyzing abilities in vitro. In plants, LIP1 seems to play a negative role in regulating circadian period that can be suppressed by light. LIP1 also seems to negatively affect light-pulse-dependent resetting of the clock, especially during the first portion of the subjective evening. LIP1 expression levels are not significantly affected by the circadian clock in seedlings grown under LL conditions. The levels of the YFP:LIP1 protein expressed under the control of the 35S promoter, shows a low amplitude variation, with protein levels peaking near the beginning of subjective night under LL conditions. In hypocotyl epidermal cells of dark and light-grown seedlings, a YFP:LIP1 fusion protein can be seen in the cytoplasm and the nucleus, and does not cluster in nuclear speckles. LIP1 may also be involved in photomorphogenesis.; Light Insensitive Period1 (LIP1); FUNCTIONS IN: GTPase activity; INVOLVED IN: circadian regulation of gene expression, photomorphogenesis; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), RNA polymerase sigma factor 54, interaction (InterPro:IPR002078); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT5G09910.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 336.0) & (original description: no original description)


Gene families : OG_42_0005550 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005550_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00009_0260
Cluster HCCA clusters: Cluster_2


Type GO Term Name Evidence Source
MF GO:0003924 GTPase activity IEA InterProScan predictions
MF GO:0005525 GTP binding IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0001522 pseudouridine synthesis IEP Predicted GO
MF GO:0003723 RNA binding IEP Predicted GO
MF GO:0003725 double-stranded RNA binding IEP Predicted GO
MF GO:0009982 pseudouridine synthase activity IEP Predicted GO
MF GO:0016866 intramolecular transferase activity IEP Predicted GO
MF GO:0071949 FAD binding IEP Predicted GO
InterPro domains Description Start Stop
IPR001806 Small_GTPase 21 173
No external refs found!