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  5. Kfl00019_0590

Kfl00019_0590 (kfl00019_0590_v1.1)


Aliases : kfl00019_0590_v1.1

Description : (at3g55360 : 333.0) Enoyl-CoA reductase is involved in all very long chain fatty acids (VLCFA) elongation reactions that are required for cuticular wax, storage lipid and sphingolipid metabolism. The protein is located in the ER, but in contrast to its yeast homolog TSC13 is not particularly enriched in the nuclear envelope-vacuole junction. Mutants in this gene show abnormal organ morphology and stem glossiness. Cells in all tissues are only about 1/3 of the size of wild type cells. The morphological changes are most likely to result from the reduction in the VLCFA content of sphingolipids. Mutants also show abnormalities in the endocytic membrane organization and transport.; ECERIFERUM 10 (CER10); FUNCTIONS IN: fatty acid elongase activity, trans-2-enoyl-CoA reductase (NADPH) activity, 3-oxo-5-alpha-steroid 4-dehydrogenase activity; INVOLVED IN: sphingolipid metabolic process, wax biosynthetic process; LOCATED IN: endoplasmic reticulum, fatty acid elongase complex, plasma membrane, endoplasmic reticulum membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal (InterPro:IPR001104); BEST Arabidopsis thaliana protein match is: 3-oxo-5-alpha-steroid 4-dehydrogenase family protein (TAIR:AT5G16010.1); Has 1087 Blast hits to 1087 proteins in 269 species: Archae - 0; Bacteria - 73; Metazoa - 353; Fungi - 144; Plants - 184; Viruses - 0; Other Eukaryotes - 333 (source: NCBI BLink). & (reliability: 666.0) & (original description: no original description)


Gene families : OG_42_0006976 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006976_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00019_0590
Cluster HCCA clusters: Cluster_2

Target Alias Description ECC score Gene Family Method Actions
Mp1g18200.1 No alias enoyl-CoA reductase (ECR) 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
BP GO:0006629 lipid metabolic process IEA InterProScan predictions
MF GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004523 RNA-DNA hybrid ribonuclease activity IEP Predicted GO
MF GO:0004556 alpha-amylase activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
CC GO:0005783 endoplasmic reticulum IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006891 intra-Golgi vesicle-mediated transport IEP Predicted GO
MF GO:0008233 peptidase activity IEP Predicted GO
BP GO:0015672 monovalent inorganic cation transport IEP Predicted GO
BP GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient IEP Predicted GO
BP GO:0015991 ATP hydrolysis coupled proton transport IEP Predicted GO
MF GO:0016160 amylase activity IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
MF GO:0016854 racemase and epimerase activity IEP Predicted GO
MF GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives IEP Predicted GO
MF GO:0016868 intramolecular transferase activity, phosphotransferases IEP Predicted GO
CC GO:0017119 Golgi transport complex IEP Predicted GO
MF GO:0019239 deaminase activity IEP Predicted GO
BP GO:0019725 cellular homeostasis IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
BP GO:0031123 RNA 3'-end processing IEP Predicted GO
BP GO:0031124 mRNA 3'-end processing IEP Predicted GO
BP GO:0034220 ion transmembrane transport IEP Predicted GO
CC GO:0044431 Golgi apparatus part IEP Predicted GO
CC GO:0044444 cytoplasmic part IEP Predicted GO
BP GO:0045454 cell redox homeostasis IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
MF GO:0070011 peptidase activity, acting on L-amino acid peptides IEP Predicted GO
BP GO:0090662 ATP hydrolysis coupled transmembrane transport IEP Predicted GO
BP GO:0098655 cation transmembrane transport IEP Predicted GO
BP GO:0098660 inorganic ion transmembrane transport IEP Predicted GO
BP GO:0098662 inorganic cation transmembrane transport IEP Predicted GO
CC GO:0099023 tethering complex IEP Predicted GO
BP GO:0099131 ATP hydrolysis coupled ion transmembrane transport IEP Predicted GO
BP GO:0099132 ATP hydrolysis coupled cation transmembrane transport IEP Predicted GO
BP GO:1902600 proton transmembrane transport IEP Predicted GO
InterPro domains Description Start Stop
IPR001104 3-oxo-5_a-steroid_4-DH_C 166 306
No external refs found!