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  5. Kfl00031_0470

Kfl00031_0470 (kfl00031_0470_v1.1)


Aliases : kfl00031_0470_v1.1

Description : (at1g50240 : 422.0) The FUSED (FU) gene belongs to Ser/Thr protein kinase family and has a key role in the hedgehog signaling pathway known to control cell proliferation and patterning in fruit flies and humans . Arabidopsis thaliana genome has a single Fu gene. Cytokinesis-defective mutants, which we named two-in-one (tio), result from mutations in Arabidopsis Fu. Phenotypic analysis of tio mutants reveals an essential role for TIO in conventional modes of cytokinesis in plant meristems and during male gametogenesis. TIO is tightly localized to the midline of the nascent phragmoplast and remains associated with the expanding phragmoplast ring. This gene was previously annotated as two gene models, AT1G50230.1 and AT1G50240.1, however the experimental evidence exists (Oh et al, Current Biology, 2005) showing that these two models are in fact single gene, named FUSED.; FUSED (FU); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Armadillo-like helical (InterPro:IPR011989), Armadillo (InterPro:IPR000225), 26S proteasome non-ATPase regulatory subunit 5 (InterPro:IPR019538), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Armadillo-type fold (InterPro:IPR016024); BEST Arabidopsis thaliana protein match is: serine/threonine protein kinase 2 (TAIR:AT3G08720.2); Has 138334 Blast hits to 135590 proteins in 4834 species: Archae - 164; Bacteria - 15793; Metazoa - 51363; Fungi - 13983; Plants - 33508; Viruses - 544; Other Eukaryotes - 22979 (source: NCBI BLink). & (q6x4a2|cipk1_orysa : 134.0) CIPK-like protein 1 (EC 2.7.11.1) (OsCK1) - Oryza sativa (Rice) & (reliability: 844.0) & (original description: no original description)


Gene families : OG_42_0006166 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006166_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00031_0470
Cluster HCCA clusters: Cluster_109

Target Alias Description ECC score Gene Family Method Actions
Cre09.g412750 No alias Protein kinase family protein with ARM repeat domain 0.01 Orthogroups_2024-Update
Glyma.10G118100 No alias Protein kinase family protein with ARM repeat domain 0.02 Orthogroups_2024-Update
Glyma.20G069700 No alias Protein kinase family protein with ARM repeat domain 0.03 Orthogroups_2024-Update
Solyc03g096890 No alias ATP binding protein, putative isoform 1 (AHRD V3.3 ***... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0004672 protein kinase activity IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
BP GO:0006468 protein phosphorylation IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity IEP Predicted GO
MF GO:0004252 serine-type endopeptidase activity IEP Predicted GO
MF GO:0004659 prenyltransferase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0006528 asparagine metabolic process IEP Predicted GO
BP GO:0006529 asparagine biosynthetic process IEP Predicted GO
MF GO:0008236 serine-type peptidase activity IEP Predicted GO
MF GO:0008318 protein prenyltransferase activity IEP Predicted GO
BP GO:0010970 transport along microtubule IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor IEP Predicted GO
MF GO:0017171 serine hydrolase activity IEP Predicted GO
BP GO:0018342 protein prenylation IEP Predicted GO
BP GO:0030705 cytoskeleton-dependent intracellular transport IEP Predicted GO
MF GO:0030976 thiamine pyrophosphate binding IEP Predicted GO
BP GO:0031503 protein-containing complex localization IEP Predicted GO
BP GO:0042073 intraciliary transport IEP Predicted GO
BP GO:0097354 prenylation IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
BP GO:0098840 protein transport along microtubule IEP Predicted GO
BP GO:0099111 microtubule-based transport IEP Predicted GO
BP GO:0099118 microtubule-based protein transport IEP Predicted GO
InterPro domains Description Start Stop
IPR000719 Prot_kinase_dom 4 256
No external refs found!