Kfl00058_0350 (kfl00058_0350_v1.1)


Aliases : kfl00058_0350_v1.1

Description : (q43082|hem3_pea : 476.0) Porphobilinogen deaminase, chloroplast precursor (EC 2.5.1.61) (PBG) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) - Pisum sativum (Garden pea) & (at5g08280 : 462.0) Encodes a protein with porphobilinogen deaminase activity. This protein is targeted to the chloroplast.; hydroxymethylbilane synthase (HEMC); FUNCTIONS IN: hydroxymethylbilane synthase activity; INVOLVED IN: chlorophyll biosynthetic process, defense response to bacterium, porphyrin biosynthetic process; LOCATED IN: apoplast, chloroplast, chloroplast stroma, chloroplast envelope; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Porphobilinogen deaminase, dipyrromethane cofactor binding site (InterPro:IPR022419), Tetrapyrrole biosynthesis, hydroxymethylbilane synthase (InterPro:IPR000860), Porphobilinogen deaminase, N-terminal (InterPro:IPR022417), Porphobilinogen deaminase, C-terminal domain (InterPro:IPR022418); Has 7343 Blast hits to 7329 proteins in 2247 species: Archae - 198; Bacteria - 4150; Metazoa - 157; Fungi - 178; Plants - 78; Viruses - 0; Other Eukaryotes - 2582 (source: NCBI BLink). & (reliability: 924.0) & (original description: no original description)


Gene families : OG_42_0004692 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004692_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00058_0350
Cluster HCCA clusters: Cluster_52

Target Alias Description ECC score Gene Family Method Actions
At5g08280 No alias Porphobilinogen deaminase, chloroplastic... 0.02 Orthogroups_2024-Update
Cre16.g663900 No alias hydroxymethylbilane synthase 0.02 Orthogroups_2024-Update
Glyma.12G021100 No alias hydroxymethylbilane synthase 0.04 Orthogroups_2024-Update
LOC_Os02g07230 No alias porphobilinogen deaminase, chloroplast precursor,... 0.03 Orthogroups_2024-Update
MA_10437242g0030 No alias (q43082|hem3_pea : 487.0) Porphobilinogen deaminase,... 0.02 Orthogroups_2024-Update
Potri.007G072500 No alias hydroxymethylbilane synthase 0.02 Orthogroups_2024-Update
Pp1s116_53V6 No alias porphobilinogen deaminase 0.07 Orthogroups_2024-Update
Sobic.004G054500.1 No alias porphobilinogen deaminase *(HEMC) & EC_2.5 transferase... 0.05 Orthogroups_2024-Update
Sopen07g034650 No alias Porphobilinogen deaminase, dipyromethane cofactor binding domain 0.04 Orthogroups_2024-Update
evm.model.tig00000241.50 No alias (q43082|hem3_pea : 177.0) Porphobilinogen deaminase,... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0004418 hydroxymethylbilane synthase activity IEA InterProScan predictions
BP GO:0033014 tetrapyrrole biosynthetic process IEA InterProScan predictions
Type GO Term Name Evidence Source
BP GO:0000413 protein peptidyl-prolyl isomerization IEP Predicted GO
MF GO:0003755 peptidyl-prolyl cis-trans isomerase activity IEP Predicted GO
MF GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity IEP Predicted GO
MF GO:0005506 iron ion binding IEP Predicted GO
BP GO:0006072 glycerol-3-phosphate metabolic process IEP Predicted GO
BP GO:0006720 isoprenoid metabolic process IEP Predicted GO
BP GO:0006721 terpenoid metabolic process IEP Predicted GO
BP GO:0006778 porphyrin-containing compound metabolic process IEP Predicted GO
BP GO:0006779 porphyrin-containing compound biosynthetic process IEP Predicted GO
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
MF GO:0008171 O-methyltransferase activity IEP Predicted GO
BP GO:0008299 isoprenoid biosynthetic process IEP Predicted GO
MF GO:0008483 transaminase activity IEP Predicted GO
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Predicted GO
CC GO:0009521 photosystem IEP Predicted GO
CC GO:0009522 photosystem I IEP Predicted GO
CC GO:0009538 photosystem I reaction center IEP Predicted GO
BP GO:0015979 photosynthesis IEP Predicted GO
BP GO:0015994 chlorophyll metabolic process IEP Predicted GO
BP GO:0015995 chlorophyll biosynthetic process IEP Predicted GO
BP GO:0016114 terpenoid biosynthetic process IEP Predicted GO
BP GO:0016226 iron-sulfur cluster assembly IEP Predicted GO
MF GO:0016725 oxidoreductase activity, acting on CH or CH2 groups IEP Predicted GO
MF GO:0016769 transferase activity, transferring nitrogenous groups IEP Predicted GO
MF GO:0016853 isomerase activity IEP Predicted GO
MF GO:0016859 cis-trans isomerase activity IEP Predicted GO
BP GO:0018193 peptidyl-amino acid modification IEP Predicted GO
BP GO:0018208 peptidyl-proline modification IEP Predicted GO
CC GO:0019898 extrinsic component of membrane IEP Predicted GO
BP GO:0022607 cellular component assembly IEP Predicted GO
BP GO:0031163 metallo-sulfur cluster assembly IEP Predicted GO
BP GO:0042440 pigment metabolic process IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
CC GO:0044436 thylakoid part IEP Predicted GO
BP GO:0046148 pigment biosynthetic process IEP Predicted GO
BP GO:0046168 glycerol-3-phosphate catabolic process IEP Predicted GO
MF GO:0046406 magnesium protoporphyrin IX methyltransferase activity IEP Predicted GO
MF GO:0046429 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
MF GO:0050661 NADP binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
MF GO:0051536 iron-sulfur cluster binding IEP Predicted GO
MF GO:0051539 4 iron, 4 sulfur cluster binding IEP Predicted GO
MF GO:0051540 metal cluster binding IEP Predicted GO
MF GO:0052592 oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor IEP Predicted GO
BP GO:0052646 alditol phosphate metabolic process IEP Predicted GO
BP GO:0055114 oxidation-reduction process IEP Predicted GO
MF GO:0070402 NADPH binding IEP Predicted GO
MF GO:0070567 cytidylyltransferase activity IEP Predicted GO
CC GO:0098796 membrane protein complex IEP Predicted GO
BP GO:1901136 carbohydrate derivative catabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR022417 Porphobilin_deaminase_N 94 304
IPR022418 Porphobilinogen_deaminase_C 318 390
No external refs found!