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  5. Kfl00066_0070

Kfl00066_0070 (kfl00066_0070_v1.1)


Aliases : kfl00066_0070_v1.1

Description : (at5g41370 : 1026.0) Encodes XPB1, a DNA repair protein and transcription factor. Arabidopsis thaliana has duplicated XPB gene (AtXPB1 and AtXPB2, with high similarity to each other). XPB proteins are involved in both DNA repair and transcription, they are component of the transcription factor IIH (TFIIH) and are responsible for DNA helicase activity during nucleotide (nt) excision repair (NER). Complementation assays in yeast rad25 mutant strains suggest the involvement of AtXPB2 in DNA repair. Although both genes are expressed in a constitutive manner during the plant life cycle, Northern blot analyses suggest that light modulates the expression level of both XPB copies.; homolog of xeroderma pigmentosum complementation group B 1 (XPB1); FUNCTIONS IN: in 7 functions; INVOLVED IN: response to UV, response to toxin; LOCATED IN: nucleus, cytoplasm; EXPRESSED IN: whole plant, male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, seedling growth; CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), DEAD-like helicase, N-terminal (InterPro:IPR014001), Xeroderma pigmentosum group B protein (XP-B) (InterPro:IPR001161), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: homolog of Xeroderma pigmentosum complementation group B 2 (TAIR:AT5G41360.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 2052.0) & (original description: no original description)


Gene families : OG_42_0003616 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003616_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Klebsormidium release: Kfl00066_0070
Cluster HCCA clusters: Cluster_120

Target Alias Description ECC score Gene Family Method Actions
LOC_Os01g49680 No alias DNA repair helicase XPB2, putative, expressed 0.01 Orthogroups_2024-Update
PSME_00003318-RA No alias (at5g41370 : 667.0) Encodes XPB1, a DNA repair protein... 0.03 Orthogroups_2024-Update
Seita.7G086200.1 No alias component *(SSL2/XPB) of multifunctional TFIIh complex &... 0.03 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
MF GO:0016787 hydrolase activity IEA InterProScan predictions
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Type GO Term Name Evidence Source
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005789 endoplasmic reticulum membrane IEP Predicted GO
BP GO:0006013 mannose metabolic process IEP Predicted GO
MF GO:0008131 primary amine oxidase activity IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
BP GO:0009308 amine metabolic process IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEP Predicted GO
MF GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors IEP Predicted GO
MF GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor IEP Predicted GO
MF GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEP Predicted GO
MF GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
CC GO:0030014 CCR4-NOT complex IEP Predicted GO
CC GO:0030119 AP-type membrane coat adaptor complex IEP Predicted GO
CC GO:0030131 clathrin adaptor complex IEP Predicted GO
BP GO:0032787 monocarboxylic acid metabolic process IEP Predicted GO
MF GO:0043015 gamma-tubulin binding IEP Predicted GO
MF GO:0045300 acyl-[acyl-carrier-protein] desaturase activity IEP Predicted GO
MF GO:0048038 quinone binding IEP Predicted GO
InterPro domains Description Start Stop
IPR032438 ERCC3_RAD25_C 482 730
IPR032830 XPB/Ssl2_N 85 210
IPR006935 Helicase/UvrB_N 299 456
No external refs found!