Kfl00079_0160 (kfl00079_0160_v1.1)

Aliases : kfl00079_0160_v1.1

Description : (p56336|if5a4_soltu : 240.0) Eukaryotic translation initiation factor 5A-4 (eIF-5A-4) (eIF-4D) - Solanum tuberosum (Potato) & (at1g13950 : 232.0) Encodes eukaryotic translation initiation factor 5A (EIF-5A).In mammalian cells it functions as a shuttle protein that translocates mRNA from the nucleus to cytoplasmic ribosomes. Overexpression results in an increase in both primary and secondary xylem formation. In RNAi suppressed lines, xylem formation is reduced.; eukaryotic elongation factor 5A-1 (ELF5A-1); FUNCTIONS IN: ribosome binding, RNA binding, translation elongation factor activity, translation initiation factor activity; INVOLVED IN: translational initiation, xylem development; LOCATED IN: cellular_component unknown; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 11 growth stages; CONTAINS InterPro DOMAIN/s: Nucleic acid-binding, OB-fold (InterPro:IPR012340), Translation elongation factor, IF5A, hypusine site (InterPro:IPR019769), Translation protein SH3-like, subgroup (InterPro:IPR014722), Translation elongation factor, IF5A (InterPro:IPR001884), Translation elongation factor, IF5A C-terminal (InterPro:IPR020189), Translation protein SH3-like (InterPro:IPR008991), Nucleic acid-binding, OB-fold-like (InterPro:IPR016027), KOW (InterPro:IPR005824); BEST Arabidopsis thaliana protein match is: eukaryotic elongation factor 5A-3 (TAIR:AT1G69410.1); Has 1356 Blast hits to 1355 proteins in 415 species: Archae - 264; Bacteria - 0; Metazoa - 366; Fungi - 246; Plants - 261; Viruses - 0; Other Eukaryotes - 219 (source: NCBI BLink). & (reliability: 464.0) & (original description: no original description)

Gene families : OG_42_0001304 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001304_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00079_0160
Cluster	HCCA clusters: Cluster_13

Target	Alias	Description	ECC score	Gene Family Method	Actions
A4A49_55854	No alias	eukaryotic translation initiation factor 5a-2	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003723	RNA binding	IEA	InterProScan predictions
MF	GO:0003746	translation elongation factor activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
BP	GO:0006414	translational elongation	None	Extended
BP	GO:0006417	regulation of translation	None	Extended
BP	GO:0006448	regulation of translational elongation	None	Extended
BP	GO:0006449	regulation of translational termination	None	Extended
BP	GO:0006452	translational frameshifting	IEA	InterProScan predictions
MF	GO:0008135	translation factor activity, RNA binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009058	biosynthetic process	None	Extended
BP	GO:0009059	macromolecule biosynthetic process	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009891	positive regulation of biosynthetic process	None	Extended
BP	GO:0009893	positive regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010557	positive regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0010604	positive regulation of macromolecule metabolic process	None	Extended
BP	GO:0010608	posttranscriptional regulation of gene expression	None	Extended
BP	GO:0010628	positive regulation of gene expression	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031325	positive regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0031328	positive regulation of cellular biosynthetic process	None	Extended
BP	GO:0032268	regulation of cellular protein metabolic process	None	Extended
BP	GO:0032270	positive regulation of cellular protein metabolic process	None	Extended
BP	GO:0034248	regulation of cellular amide metabolic process	None	Extended
BP	GO:0034250	positive regulation of cellular amide metabolic process	None	Extended
BP	GO:0034645	cellular macromolecule biosynthetic process	None	Extended
MF	GO:0043021	ribonucleoprotein complex binding	None	Extended
MF	GO:0043022	ribosome binding	IEA	InterProScan predictions
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043243	positive regulation of protein complex disassembly	None	Extended
BP	GO:0043244	regulation of protein complex disassembly	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044249	cellular biosynthetic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
MF	GO:0044877	protein-containing complex binding	None	Extended
BP	GO:0045727	positive regulation of translation	None	Extended
BP	GO:0045901	positive regulation of translational elongation	IEA	InterProScan predictions
BP	GO:0045905	positive regulation of translational termination	IEA	InterProScan predictions
BP	GO:0048518	positive regulation of biological process	None	Extended
BP	GO:0048522	positive regulation of cellular process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051128	regulation of cellular component organization	None	Extended
BP	GO:0051130	positive regulation of cellular component organization	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051173	positive regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051246	regulation of protein metabolic process	None	Extended
BP	GO:0051247	positive regulation of protein metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended
BP	GO:1901576	organic substance biosynthetic process	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0001510	RNA methylation	IEP	Predicted GO
CC	GO:0005730	nucleolus	IEP	Predicted GO
BP	GO:0006383	transcription by RNA polymerase III	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0006400	tRNA modification	IEP	Predicted GO
BP	GO:0006873	cellular ion homeostasis	IEP	Predicted GO
BP	GO:0006875	cellular metal ion homeostasis	IEP	Predicted GO
BP	GO:0006879	cellular iron ion homeostasis	IEP	Predicted GO
MF	GO:0008134	transcription factor binding	IEP	Predicted GO
MF	GO:0008168	methyltransferase activity	IEP	Predicted GO
MF	GO:0008173	RNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008175	tRNA methyltransferase activity	IEP	Predicted GO
MF	GO:0008199	ferric iron binding	IEP	Predicted GO
MF	GO:0008536	Ran GTPase binding	IEP	Predicted GO
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016426	tRNA (adenine) methyltransferase activity	IEP	Predicted GO
MF	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity	IEP	Predicted GO
MF	GO:0016741	transferase activity, transferring one-carbon groups	IEP	Predicted GO
MF	GO:0016742	hydroxymethyl-, formyl- and related transferase activity	IEP	Predicted GO
MF	GO:0017016	Ras GTPase binding	IEP	Predicted GO
BP	GO:0019725	cellular homeostasis	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
BP	GO:0030003	cellular cation homeostasis	IEP	Predicted GO
BP	GO:0030488	tRNA methylation	IEP	Predicted GO
MF	GO:0031267	small GTPase binding	IEP	Predicted GO
CC	GO:0031515	tRNA (m1A) methyltransferase complex	IEP	Predicted GO
CC	GO:0034708	methyltransferase complex	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
BP	GO:0042592	homeostatic process	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
BP	GO:0043414	macromolecule methylation	IEP	Predicted GO
CC	GO:0043527	tRNA methyltransferase complex	IEP	Predicted GO
BP	GO:0044085	cellular component biogenesis	IEP	Predicted GO
BP	GO:0046916	cellular transition metal ion homeostasis	IEP	Predicted GO
BP	GO:0048878	chemical homeostasis	IEP	Predicted GO
BP	GO:0050801	ion homeostasis	IEP	Predicted GO
MF	GO:0051011	microtubule minus-end binding	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0055065	metal ion homeostasis	IEP	Predicted GO
BP	GO:0055072	iron ion homeostasis	IEP	Predicted GO
BP	GO:0055076	transition metal ion homeostasis	IEP	Predicted GO
BP	GO:0055080	cation homeostasis	IEP	Predicted GO
BP	GO:0055082	cellular chemical homeostasis	IEP	Predicted GO
BP	GO:0065008	regulation of biological quality	IEP	Predicted GO
BP	GO:0098771	inorganic ion homeostasis	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR013185	Transl_elong_KOW-like	24	54
IPR020189	Transl_elong_IF5A_C	85	155

External Links

No external refs found!

Kfl00079_0160 (kfl00079_0160_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation