Kfl00116_0090 (kfl00116_0090_v1.1,...)


Aliases : kfl00116_0090_v1.1, kfl00116_0090_v1.1

Description : (at1g04020 : 184.0) Encodes a protein containing two tandem BRCA1 C-Terminal (BRCT) domains, which function in phosphorylation-dependent proteinñprotein interactions.Loss of function mutations cause defects in meristem organization due to failure to repress WUS. BARD1 binds to WUS promoter and over expression of BARD reduces the extent of WUS expression.; breast cancer associated RING 1 (BARD1); FUNCTIONS IN: transcription coactivator activity, DNA binding; INVOLVED IN: DNA repair, regulation of meristem structural organization, leaf development; LOCATED IN: intracellular; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, PHD-type (InterPro:IPR001965), BRCT (InterPro:IPR001357); BEST Arabidopsis thaliana protein match is: breast cancer susceptibility1 (TAIR:AT4G21070.1); Has 6045 Blast hits to 5706 proteins in 320 species: Archae - 0; Bacteria - 47; Metazoa - 4577; Fungi - 362; Plants - 542; Viruses - 11; Other Eukaryotes - 506 (source: NCBI BLink). & (reliability: 354.0) & (original description: no original description)


Gene families : OG_42_0000927 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000927_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00116_0090
Cluster HCCA clusters: Cluster_38

Target Alias Description ECC score Gene Family Method Actions
At1g04020 No alias Breast cancer associated RING 1... 0.05 Orthogroups_2024-Update
Cre07.g334650 No alias breast cancer susceptibility1 0.09 Orthogroups_2024-Update
Glyma.13G220400 No alias breast cancer susceptibility1 0.04 Orthogroups_2024-Update
Glyma.15G092000 No alias breast cancer susceptibility1 0.05 Orthogroups_2024-Update
HORVU1Hr1G069020.23 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.02 Orthogroups_2024-Update
HORVU2Hr1G088840.1 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.01 Orthogroups_2024-Update
LOC_Os05g40810 No alias BRCA1 C Terminus domain containing protein, expressed 0.02 Orthogroups_2024-Update
MA_187851g0010 No alias (at4g21070 : 105.0) Encodes AtBRCA1, an ortholog of the... 0.01 Orthogroups_2024-Update
PSME_00014683-RA No alias (at1g04020 : 160.0) Encodes a protein containing two... 0.02 Orthogroups_2024-Update
PSME_00045597-RA No alias (at4g21070 : 127.0) Encodes AtBRCA1, an ortholog of the... 0.02 Orthogroups_2024-Update
PSME_00045645-RA No alias (at1g04020 : 157.0) Encodes a protein containing two... 0.02 Orthogroups_2024-Update
Seita.3G183600.1 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.02 Orthogroups_2024-Update
Sobic.006G144700.1 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.02 Orthogroups_2024-Update
Sobic.009G192700.1 No alias component *(BRCA1/BARD1) of BRCA1-BARD1 ubiquitination... 0.03 Orthogroups_2024-Update
Solyc06g008210 No alias breast cancer associated RING 1 (AHRD V3.3 *** AT1G04020.1) 0.1 Orthogroups_2024-Update
Solyc08g023280 No alias RING/U-box superfamily protein (AHRD V3.3 --* AT3G07200.3) 0.09 Orthogroups_2024-Update
Sopen06g003070 No alias BRCA1 C Terminus (BRCT) domain 0.09 Orthogroups_2024-Update
Sopen08g008190 No alias BRCA1 C Terminus (BRCT) domain 0.02 Orthogroups_2024-Update
evm.model.tig00020537.14 No alias (at1g04020 : 90.1) Encodes a protein containing two... 0.08 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence

Type GO Term Name Evidence Source
MF GO:0000166 nucleotide binding IEP Predicted GO
BP GO:0000723 telomere maintenance IEP Predicted GO
BP GO:0000724 double-strand break repair via homologous recombination IEP Predicted GO
BP GO:0000725 recombinational repair IEP Predicted GO
CC GO:0000781 chromosome, telomeric region IEP Predicted GO
CC GO:0000784 nuclear chromosome, telomeric region IEP Predicted GO
CC GO:0000796 condensin complex IEP Predicted GO
MF GO:0003676 nucleic acid binding IEP Predicted GO
MF GO:0003677 DNA binding IEP Predicted GO
MF GO:0003678 DNA helicase activity IEP Predicted GO
MF GO:0003887 DNA-directed DNA polymerase activity IEP Predicted GO
MF GO:0003896 DNA primase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0004386 helicase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005634 nucleus IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006259 DNA metabolic process IEP Predicted GO
BP GO:0006260 DNA replication IEP Predicted GO
BP GO:0006269 DNA replication, synthesis of RNA primer IEP Predicted GO
BP GO:0006275 regulation of DNA replication IEP Predicted GO
BP GO:0006281 DNA repair IEP Predicted GO
BP GO:0006302 double-strand break repair IEP Predicted GO
BP GO:0006310 DNA recombination IEP Predicted GO
BP GO:0006323 DNA packaging IEP Predicted GO
BP GO:0006333 chromatin assembly or disassembly IEP Predicted GO
BP GO:0006401 RNA catabolic process IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006807 nitrogen compound metabolic process IEP Predicted GO
BP GO:0006950 response to stress IEP Predicted GO
BP GO:0006974 cellular response to DNA damage stimulus IEP Predicted GO
BP GO:0006996 organelle organization IEP Predicted GO
BP GO:0007062 sister chromatid cohesion IEP Predicted GO
BP GO:0007064 mitotic sister chromatid cohesion IEP Predicted GO
BP GO:0007076 mitotic chromosome condensation IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008156 negative regulation of DNA replication IEP Predicted GO
BP GO:0009058 biosynthetic process IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
BP GO:0009890 negative regulation of biosynthetic process IEP Predicted GO
BP GO:0009987 cellular process IEP Predicted GO
BP GO:0010558 negative regulation of macromolecule biosynthetic process IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
MF GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IEP Predicted GO
MF GO:0016772 transferase activity, transferring phosphorus-containing groups IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0019207 kinase regulator activity IEP Predicted GO
MF GO:0019887 protein kinase regulator activity IEP Predicted GO
BP GO:0022402 cell cycle process IEP Predicted GO
BP GO:0030261 chromosome condensation IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
BP GO:0031324 negative regulation of cellular metabolic process IEP Predicted GO
BP GO:0031327 negative regulation of cellular biosynthetic process IEP Predicted GO
CC GO:0031390 Ctf18 RFC-like complex IEP Predicted GO
BP GO:0032200 telomere organization IEP Predicted GO
CC GO:0032299 ribonuclease H2 complex IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033554 cellular response to stress IEP Predicted GO
MF GO:0034061 DNA polymerase activity IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
BP GO:0034641 cellular nitrogen compound metabolic process IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0043138 3'-5' DNA helicase activity IEP Predicted GO
MF GO:0043140 ATP-dependent 3'-5' DNA helicase activity IEP Predicted GO
BP GO:0043170 macromolecule metabolic process IEP Predicted GO
CC GO:0043226 organelle IEP Predicted GO
CC GO:0043227 membrane-bounded organelle IEP Predicted GO
CC GO:0043229 intracellular organelle IEP Predicted GO
CC GO:0043231 intracellular membrane-bounded organelle IEP Predicted GO
BP GO:0044237 cellular metabolic process IEP Predicted GO
BP GO:0044249 cellular biosynthetic process IEP Predicted GO
BP GO:0044260 cellular macromolecule metabolic process IEP Predicted GO
CC GO:0044424 intracellular part IEP Predicted GO
CC GO:0044427 chromosomal part IEP Predicted GO
CC GO:0044464 cell part IEP Predicted GO
CC GO:0044815 DNA packaging complex IEP Predicted GO
BP GO:0045005 DNA-dependent DNA replication maintenance of fidelity IEP Predicted GO
BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
BP GO:0048478 replication fork protection IEP Predicted GO
BP GO:0050896 response to stimulus IEP Predicted GO
BP GO:0051052 regulation of DNA metabolic process IEP Predicted GO
BP GO:0051053 negative regulation of DNA metabolic process IEP Predicted GO
BP GO:0051172 negative regulation of nitrogen compound metabolic process IEP Predicted GO
BP GO:0051276 chromosome organization IEP Predicted GO
BP GO:0051716 cellular response to stimulus IEP Predicted GO
BP GO:0060249 anatomical structure homeostasis IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
BP GO:0090304 nucleic acid metabolic process IEP Predicted GO
BP GO:0090329 regulation of DNA-dependent DNA replication IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
CC GO:0098687 chromosomal region IEP Predicted GO
MF GO:0140097 catalytic activity, acting on DNA IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
BP GO:1901576 organic substance biosynthetic process IEP Predicted GO
BP GO:1903047 mitotic cell cycle process IEP Predicted GO
BP GO:2000104 negative regulation of DNA-dependent DNA replication IEP Predicted GO
BP GO:2000113 negative regulation of cellular macromolecule biosynthetic process IEP Predicted GO
InterPro domains Description Start Stop
IPR001357 BRCT_dom 788 854
No external refs found!