Kfl00116_0220 (kfl00116_0220_v1.1)

Aliases : kfl00116_0220_v1.1

Description : (at1g08370 : 221.0) Encodes DCP1 involved in mRNA decapping. DCP1 forms a mRNA decapping complex with DCP2 (At5g13570) and VCS (VARICOSE) (At3g13300). However, unlike DCP2, DCP1 itself does not have mRNA decapping activity in vitro. DCP1, DCP2 and VCS colocalize in cytoplasmic loci, which are putative Arabidopsis mRNA processing bodies. Null mutants of DCP1, DCP2, and VCS accumulate capped mRNAs with a reduced degradation rate. These mutants also share a similar lethal phenotype at the seedling cotyledon stage, with disorganized veins, swollen root hairs, and altered epidermal cell morphology. The protein was shown by immunoprecipitation not to interact with DCP2.; decapping 1 (DCP1); CONTAINS InterPro DOMAIN/s: Dcp1-like decapping (InterPro:IPR010334); Has 3561 Blast hits to 2917 proteins in 377 species: Archae - 4; Bacteria - 239; Metazoa - 1310; Fungi - 561; Plants - 741; Viruses - 142; Other Eukaryotes - 564 (source: NCBI BLink). & (reliability: 442.0) & (original description: no original description)

Gene families : OG_42_0001999 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001999_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00116_0220
Cluster	HCCA clusters: Cluster_63

Target	Alias	Description	ECC score	Gene Family Method	Actions
Glyma.19G196300	No alias	decapping 1	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
BP	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA	IEA	InterProScan predictions
BP	GO:0000956	nuclear-transcribed mRNA catabolic process	None	Extended
MF	GO:0003674	molecular_function	None	Extended
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006401	RNA catabolic process	None	Extended
BP	GO:0006402	mRNA catabolic process	None	Extended
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008047	enzyme activator activity	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009056	catabolic process	None	Extended
BP	GO:0009057	macromolecule catabolic process	None	Extended
BP	GO:0009892	negative regulation of metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010605	negative regulation of macromolecule metabolic process	None	Extended
BP	GO:0010629	negative regulation of gene expression	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
BP	GO:0016071	mRNA metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019439	aromatic compound catabolic process	None	Extended
MF	GO:0030234	enzyme regulator activity	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
BP	GO:0034655	nucleobase-containing compound catabolic process	None	Extended
BP	GO:0043085	positive regulation of catalytic activity	IEA	InterProScan predictions
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044093	positive regulation of molecular function	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044248	cellular catabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044265	cellular macromolecule catabolic process	None	Extended
BP	GO:0044270	cellular nitrogen compound catabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0046700	heterocycle catabolic process	None	Extended
BP	GO:0048519	negative regulation of biological process	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050790	regulation of catalytic activity	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0065009	regulation of molecular function	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
BP	GO:1901361	organic cyclic compound catabolic process	None	Extended
BP	GO:1901575	organic substance catabolic process	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0015399	primary active transmembrane transporter activity	IEP	Predicted GO
MF	GO:0015405	P-P-bond-hydrolysis-driven transmembrane transporter activity	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016787	hydrolase activity	IEP	Predicted GO
MF	GO:0016817	hydrolase activity, acting on acid anhydrides	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016887	ATPase activity	IEP	Predicted GO
MF	GO:0017111	nucleoside-triphosphatase activity	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
MF	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEP	Predicted GO
MF	GO:0043492	ATPase activity, coupled to movement of substances	IEP	Predicted GO
BP	GO:0055085	transmembrane transport	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR010334	Dcp1	47	161

External Links

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Kfl00116_0220 (kfl00116_0220_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation