Kfl00130_0050 (kfl00130_0050_v1.1)


Aliases : kfl00130_0050_v1.1

Description : (at3g57300 : 966.0) Encodes the Arabidopsis INO80 ortholog of the SWI/SNF ATPase family. Functions as a positive regulator of DNA homologous recombination (HR). In INO80 mutants, the HR frequency is reduced to 15% of that in the wild-type. Mutation in INO80 does not affect sensitivity to genotoxic agents and efficiency of T-DNA integration. INO80 was also shown to regulate a subset of the Arabidopsis transcriptome.; INO80 ortholog (INO80); FUNCTIONS IN: helicase activity, DNA binding, nucleic acid binding, ATP binding; INVOLVED IN: somatic cell DNA recombination, positive regulation of DNA repair, regulation of transcription; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA binding domain, INO80 (InterPro:IPR020838), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021), SNF2-related (InterPro:IPR000330); BEST Arabidopsis thaliana protein match is: SNF2 domain-containing protein / helicase domain-containing protein (TAIR:AT3G12810.1). & (q7g8y3|isw2_orysa : 274.0) Probable chromatin remodelling complex ATPase chain (EC 3.6.1.-) (ISW2-like) (Sucrose nonfermenting protein 2 homolog) - Oryza sativa (Rice) & (reliability: 1932.0) & (original description: no original description)


Gene families : OG_42_0006128 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006128_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00130_0050
Cluster HCCA clusters: Cluster_135

Target Alias Description ECC score Gene Family Method Actions
Glyma.10G106500 No alias INO80 ortholog 0.02 Orthogroups_2024-Update
MA_3312g0010 No alias (at3g57300 : 1489.0) Encodes the Arabidopsis INO80... 0.01 Orthogroups_2024-Update
evm.model.contig_664.3 No alias (at3g57300 : 386.0) Encodes the Arabidopsis INO80... 0.01 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003677 DNA binding IEA InterProScan predictions
MF GO:0005524 ATP binding IEA InterProScan predictions
Type GO Term Name Evidence Source
MF GO:0003688 DNA replication origin binding IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0005515 protein binding IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0009059 macromolecule biosynthetic process IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
BP GO:0034645 cellular macromolecule biosynthetic process IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
MF GO:1990837 sequence-specific double-stranded DNA binding IEP Predicted GO
InterPro domains Description Start Stop
IPR020838 DBINO 639 765
IPR000330 SNF2_N 880 1166
IPR001650 Helicase_C 1478 1590
No external refs found!