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Kfl00158_0150 (kfl00158_0150_v1.1,...)


Aliases : kfl00158_0150_v1.1, kfl00158_0150_v1.1

Description : (at3g60190 : 839.0) At3g60190 encodes Arabidopsis dynamin-related protein 1E, DRP1E, also known as EDR3, ADL4 and ADL1E, which is 624 amino acid residues long, has a predicted mass of 69.8 kDa and a pI of 7.5. Dynamin-related protein 1E belongs to a plant-specific subclass of dynamin-related proteins (DRP1), consisting of five members in Arabidopsis (A, B, C, D, E). This class is characterized by having an N-terminal GTPase domain, a central ëdynamin 2ë domain and a C-terminal GTPase effector domain (GED), a typical structure for plant dynamin-related proteins. However, this class lacks a PH domain and a proline-rich domain, which are found in classical animal dynamin-like proteins. Based on work on animal dynamins, the plant DRP1 proteins should be able to form polymeric structures that wrap around membranes to facilitate membrane tubulation and pinching off of vesicles, processes that are essential to vesicle trafficking and membrane compartmentalization. The edr3 mutation causes a P77L substitution in the G2 motif of the GTPase domain of DRP1E. edr3 mutant Arabidopsis plants display enhanced cell death in response to powdery mildew infection.; DYNAMIN-like 1E (DL1E); FUNCTIONS IN: GTP binding, GTPase activity; INVOLVED IN: response to cadmium ion, vesicle-mediated transport, defense response to fungus; LOCATED IN: mitochondrion, plasma membrane, vacuole; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dynamin GTPase effector (InterPro:IPR003130), Dynamin, GTPase domain (InterPro:IPR001401), Dynamin, GTPase region, conserved site (InterPro:IPR019762), GTPase effector domain, GED (InterPro:IPR020850), Dynamin central region (InterPro:IPR000375); BEST Arabidopsis thaliana protein match is: DYNAMIN-like 1D (TAIR:AT2G44590.3); Has 2915 Blast hits to 2753 proteins in 324 species: Archae - 2; Bacteria - 53; Metazoa - 1058; Fungi - 869; Plants - 577; Viruses - 0; Other Eukaryotes - 356 (source: NCBI BLink). & (reliability: 1578.0) & (original description: no original description)


Gene families : OG_42_0000914 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000914_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00158_0150
Cluster HCCA clusters: Cluster_64

Target Alias Description ECC score Gene Family Method Actions
183216 No alias DYNAMIN-like 1E 0.01 Orthogroups_2024-Update
90013 No alias DYNAMIN-like 1E 0.01 Orthogroups_2024-Update
Mp1g11000.1 No alias DRP1-type clathrin coated vesicle dynamin 0.04 Orthogroups_2024-Update
PSME_00020105-RA No alias (at5g42080 : 726.0) Encodes a dynamin-like protein... 0.02 Orthogroups_2024-Update
Seita.3G152400.1 No alias phragmoplastin *(DRP1) 0.02 Orthogroups_2024-Update
Sobic.003G258100.1 No alias phragmoplastin *(DRP1) 0.02 Orthogroups_2024-Update
Sobic.009G226400.1 No alias phragmoplastin *(DRP1) 0.02 Orthogroups_2024-Update
Sopen01g035380 No alias Dynamin central region 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0003924 GTPase activity IEA InterProScan predictions
MF GO:0005525 GTP binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0000271 polysaccharide biosynthetic process IEP Predicted GO
BP GO:0000272 polysaccharide catabolic process IEP Predicted GO
BP GO:0001101 response to acid chemical IEP Predicted GO
MF GO:0003830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity IEP Predicted GO
MF GO:0004096 catalase activity IEP Predicted GO
MF GO:0004345 glucose-6-phosphate dehydrogenase activity IEP Predicted GO
MF GO:0004359 glutaminase activity IEP Predicted GO
MF GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
MF GO:0004556 alpha-amylase activity IEP Predicted GO
MF GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0005976 polysaccharide metabolic process IEP Predicted GO
BP GO:0006006 glucose metabolic process IEP Predicted GO
BP GO:0006073 cellular glucan metabolic process IEP Predicted GO
BP GO:0006081 cellular aldehyde metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006777 Mo-molybdopterin cofactor biosynthetic process IEP Predicted GO
BP GO:0006793 phosphorus metabolic process IEP Predicted GO
BP GO:0006796 phosphate-containing compound metabolic process IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006820 anion transport IEP Predicted GO
BP GO:0006897 endocytosis IEP Predicted GO
BP GO:0006904 vesicle docking involved in exocytosis IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008194 UDP-glycosyltransferase activity IEP Predicted GO
BP GO:0008272 sulfate transport IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
BP GO:0009057 macromolecule catabolic process IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009250 glucan biosynthetic process IEP Predicted GO
BP GO:0009439 cyanate metabolic process IEP Predicted GO
BP GO:0010035 response to inorganic substance IEP Predicted GO
BP GO:0010167 response to nitrate IEP Predicted GO
MF GO:0015116 sulfate transmembrane transporter activity IEP Predicted GO
MF GO:0015297 antiporter activity IEP Predicted GO
BP GO:0015698 inorganic anion transport IEP Predicted GO
BP GO:0015706 nitrate transport IEP Predicted GO
MF GO:0015924 mannosyl-oligosaccharide mannosidase activity IEP Predicted GO
BP GO:0015936 coenzyme A metabolic process IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
BP GO:0016052 carbohydrate catabolic process IEP Predicted GO
MF GO:0016160 amylase activity IEP Predicted GO
MF GO:0016161 beta-amylase activity IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016491 oxidoreductase activity IEP Predicted GO
MF GO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEP Predicted GO
MF GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016759 cellulose synthase activity IEP Predicted GO
MF GO:0016760 cellulose synthase (UDP-forming) activity IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
BP GO:0017062 respiratory chain complex III assembly IEP Predicted GO
CC GO:0019008 molybdopterin synthase complex IEP Predicted GO
BP GO:0019637 organophosphate metabolic process IEP Predicted GO
BP GO:0019720 Mo-molybdopterin cofactor metabolic process IEP Predicted GO
MF GO:0030151 molybdenum ion binding IEP Predicted GO
BP GO:0030163 protein catabolic process IEP Predicted GO
BP GO:0030243 cellulose metabolic process IEP Predicted GO
BP GO:0030244 cellulose biosynthetic process IEP Predicted GO
MF GO:0031072 heat shock protein binding IEP Predicted GO
BP GO:0033108 mitochondrial respiratory chain complex assembly IEP Predicted GO
BP GO:0033692 cellular polysaccharide biosynthetic process IEP Predicted GO
BP GO:0034551 mitochondrial respiratory chain complex III assembly IEP Predicted GO
BP GO:0042126 nitrate metabolic process IEP Predicted GO
BP GO:0042128 nitrate assimilation IEP Predicted GO
BP GO:0042816 vitamin B6 metabolic process IEP Predicted GO
BP GO:0042819 vitamin B6 biosynthetic process IEP Predicted GO
BP GO:0042822 pyridoxal phosphate metabolic process IEP Predicted GO
BP GO:0042823 pyridoxal phosphate biosynthetic process IEP Predicted GO
BP GO:0043545 molybdopterin cofactor metabolic process IEP Predicted GO
BP GO:0044042 glucan metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044264 cellular polysaccharide metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0046184 aldehyde biosynthetic process IEP Predicted GO
BP GO:0046834 lipid phosphorylation IEP Predicted GO
BP GO:0046854 phosphatidylinositol phosphorylation IEP Predicted GO
MF GO:0048037 cofactor binding IEP Predicted GO
MF GO:0050662 coenzyme binding IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051189 prosthetic group metabolic process IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
BP GO:0051273 beta-glucan metabolic process IEP Predicted GO
BP GO:0051274 beta-glucan biosynthetic process IEP Predicted GO
MF GO:0051539 4 iron, 4 sulfur cluster binding IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071941 nitrogen cycle metabolic process IEP Predicted GO
BP GO:0072348 sulfur compound transport IEP Predicted GO
BP GO:0098657 import into cell IEP Predicted GO
BP GO:0140029 exocytic process IEP Predicted GO
BP GO:1901575 organic substance catabolic process IEP Predicted GO
BP GO:1901617 organic hydroxy compound biosynthetic process IEP Predicted GO
MF GO:1901682 sulfur compound transmembrane transporter activity IEP Predicted GO
BP GO:1901698 response to nitrogen compound IEP Predicted GO
BP GO:1901700 response to oxygen-containing compound IEP Predicted GO
BP GO:2001057 reactive nitrogen species metabolic process IEP Predicted GO
InterPro domains Description Start Stop
IPR003130 GED 530 621
IPR000375 Dynamin_central 228 494
IPR022812 Dynamin_SF 39 218
No external refs found!