Kfl00216_0130 (kfl00216_0130_v1.1)

Aliases : kfl00216_0130_v1.1

Description : (at1g13980 : 722.0) Encodes a GDP/GTP exchange factor for small G-proteins of the ADP ribosylation factor (RAF) class, and as regulator of intracellular trafficking. Homologous to Sec7p and YEC2 from yeast. Involved in the specification of apical-basal pattern formation. Essential for cell division, expansion and adhesion. It appears that heteotypic binding between the DCB and C-terminal domains of two GNOM proteins is required for membrane association, however, GNOM appears to exist predominantly as a heterodimer formed through DCB-DCB interactions.; GNOM (GN); FUNCTIONS IN: protein homodimerization activity, GTP:GDP antiporter activity; INVOLVED IN: in 13 processes; LOCATED IN: intracellular; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: SEC7-like (InterPro:IPR000904); BEST Arabidopsis thaliana protein match is: GNOM-like 1 (TAIR:AT5G39500.1). & (reliability: 1444.0) & (original description: no original description)

Gene families : OG_42_0001315 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0001315_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00216_0130
Cluster	HCCA clusters: Cluster_113

Target	Alias	Description	ECC score	Gene Family Method	Actions
evm.model.tig00000241.27	No alias	(at5g19610 : 149.0) GNOM-like 2 (GNL2); FUNCTIONS IN:...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005085	guanyl-nucleotide exchange factor activity	None	Extended
MF	GO:0005086	ARF guanyl-nucleotide exchange factor activity	IEA	InterProScan predictions
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	None	Extended
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006508	proteolysis	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008233	peptidase activity	None	Extended
MF	GO:0008234	cysteine-type peptidase activity	None	Extended
BP	GO:0009966	regulation of signal transduction	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010646	regulation of cell communication	None	Extended
BP	GO:0016579	protein deubiquitination	IEA	InterProScan predictions
MF	GO:0016787	hydrolase activity	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
MF	GO:0019783	ubiquitin-like protein-specific protease activity	None	Extended
MF	GO:0019899	enzyme binding	None	Extended
BP	GO:0023051	regulation of signaling	None	Extended
BP	GO:0032012	regulation of ARF protein signal transduction	IEA	InterProScan predictions
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity	IEA	InterProScan predictions
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
BP	GO:0046578	regulation of Ras protein signal transduction	None	Extended
BP	GO:0048583	regulation of response to stimulus	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
MF	GO:0051020	GTPase binding	None	Extended
BP	GO:0051056	regulation of small GTPase mediated signal transduction	None	Extended
BP	GO:0065007	biological regulation	None	Extended
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	None	Extended
BP	GO:0070646	protein modification by small protein removal	None	Extended
BP	GO:0070647	protein modification by small protein conjugation or removal	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
MF	GO:0098772	molecular function regulator	None	Extended
MF	GO:0101005	ubiquitinyl hydrolase activity	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1902531	regulation of intracellular signal transduction	None	Extended

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Type	GO Term	Name	Evidence	Source
MF	GO:0004089	carbonate dehydratase activity	IEP	Predicted GO
MF	GO:0004888	transmembrane signaling receptor activity	IEP	Predicted GO
MF	GO:0004930	G protein-coupled receptor activity	IEP	Predicted GO
MF	GO:0005049	nuclear export signal receptor activity	IEP	Predicted GO
BP	GO:0006488	dolichol-linked oligosaccharide biosynthetic process	IEP	Predicted GO
BP	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process	IEP	Predicted GO
BP	GO:0007155	cell adhesion	IEP	Predicted GO
BP	GO:0007160	cell-matrix adhesion	IEP	Predicted GO
BP	GO:0007186	G protein-coupled receptor signaling pathway	IEP	Predicted GO
MF	GO:0016836	hydro-lyase activity	IEP	Predicted GO
BP	GO:0022610	biological adhesion	IEP	Predicted GO
BP	GO:0031589	cell-substrate adhesion	IEP	Predicted GO
MF	GO:0038023	signaling receptor activity	IEP	Predicted GO
MF	GO:0060089	molecular transducer activity	IEP	Predicted GO
MF	GO:0140104	molecular carrier activity	IEP	Predicted GO
MF	GO:0140142	nucleocytoplasmic carrier activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR000904	Sec7_dom	554	737
IPR001394	Peptidase_C19_UCH	2218	2562
IPR032691	Sec7_N	320	465

External Links

No external refs found!

Kfl00216_0130 (kfl00216_0130_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation