Kfl00265_0060 (kfl00265_0060_v1.1)

Aliases : kfl00265_0060_v1.1

Description : (at1g01040 : 525.0) Encodes a Dicer homolog. Dicer is a RNA helicase involved in microRNA processing. Mutations in this locus can result in embryo lethality. Embryo shape at seed maturity is globular-elongate. Other mutants convert the floral meristems to an indeterminate state, others yet show defects in ovule development. mRNA is expressed in all shoot tissues. DCL1 is able to produce miRNAs and siRNAs.; dicer-like 1 (DCL1); CONTAINS InterPro DOMAIN/s: Restriction endonuclease, type I, R subunit/Type III, Res subunit (InterPro:IPR006935), Double-stranded RNA-binding (InterPro:IPR001159), Argonaute/Dicer protein, PAZ (InterPro:IPR003100), Ribonuclease III (InterPro:IPR000999), Double-stranded RNA-binding-like (InterPro:IPR014720), DEAD-like helicase, N-terminal (InterPro:IPR014001), DNA/RNA helicase, C-terminal (InterPro:IPR001650), Dicer double-stranded RNA-binding fold (InterPro:IPR005034), Helicase, superfamily 1/2, ATP-binding domain (InterPro:IPR014021); BEST Arabidopsis thaliana protein match is: dicer-like 3 (TAIR:AT3G43920.1). & (reliability: 1050.0) & (original description: no original description)

Gene families : OG_42_0000292 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000292_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00265_0060
Cluster	HCCA clusters: Cluster_120

Target	Alias	Description	ECC score	Gene Family Method
At3g03300	No alias	Endoribonuclease Dicer homolog 2...	0.02	Orthogroups_2024-Update
Bradi1g15440	No alias	dicer-like 2	0.01	Orthogroups_2024-Update
Bradi2g23187	No alias	dicer-like 3	0.02	Orthogroups_2024-Update
Bradi3g29287	No alias	dicer-like 3	0.01	Orthogroups_2024-Update
Bradi5g15337	No alias	dicer-like 4	0.04	Orthogroups_2024-Update
Glyma.04G057400	No alias	dicer-like 3	0.01	Orthogroups_2024-Update
Glyma.19G261200	No alias	dicer-like 1	0.02	Orthogroups_2024-Update
HORVU2Hr1G088270.21	No alias	endoribonuclease (DCL4) of transacting siRNA pathway	0.01	Orthogroups_2024-Update
LOC_Os01g37050	No alias	ribonuclease III domain protein, putative, expressed	0.01	Orthogroups_2024-Update
LOC_Os03g02970	No alias	Dicer, putative, expressed	0.01	Orthogroups_2024-Update
PSME_00003728-RA	No alias	(at1g01040 : 178.0) Encodes a Dicer homolog. Dicer is a...	0.02	Orthogroups_2024-Update
Pp1s149_36V6	No alias	dicer-like protein	0.02	Orthogroups_2024-Update
Pp1s82_159V6	No alias	dicer-like protein	0.02	Orthogroups_2024-Update
Pp1s82_160V6	No alias	dicer-like protein	0.02	Orthogroups_2024-Update
Seita.9G179200.1	No alias	endoribonuclease (DCL2) of transacting siRNA pathway	0.02	Orthogroups_2024-Update
Sobic.003G396700.1	No alias	endoribonuclease *(DCL3)	0.01	Orthogroups_2024-Update
Sopen08g021150	No alias	Ribonuclease III domain	0.01	Orthogroups_2024-Update
evm.model.contig_3414.2	No alias	(at3g03300 : 120.0) Encodes a Dicer-like protein that...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003676	nucleic acid binding	None	Extended
MF	GO:0003677	DNA binding	IEA	InterProScan predictions
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0004518	nuclease activity	None	Extended
MF	GO:0004519	endonuclease activity	None	Extended
MF	GO:0004521	endoribonuclease activity	None	Extended
MF	GO:0004525	ribonuclease III activity	IEA	InterProScan predictions
MF	GO:0004540	ribonuclease activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	InterProScan predictions
MF	GO:0005524	ATP binding	IEA	InterProScan predictions
BP	GO:0006139	nucleobase-containing compound metabolic process	None	Extended
BP	GO:0006396	RNA processing	IEA	InterProScan predictions
BP	GO:0006725	cellular aromatic compound metabolic process	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
MF	GO:0008144	drug binding	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0016070	RNA metabolic process	None	Extended
MF	GO:0016787	hydrolase activity	IEA	InterProScan predictions
MF	GO:0016788	hydrolase activity, acting on ester bonds	None	Extended
MF	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	IEA	InterProScan predictions
MF	GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	None	Extended
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0030554	adenyl nucleotide binding	None	Extended
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032559	adenyl ribonucleotide binding	None	Extended
BP	GO:0034641	cellular nitrogen compound metabolic process	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0046483	heterocycle metabolic process	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0090304	nucleic acid metabolic process	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:0140098	catalytic activity, acting on RNA	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
BP	GO:1901360	organic cyclic compound metabolic process	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000105	histidine biosynthetic process	IEP	Predicted GO
BP	GO:0000375	RNA splicing, via transesterification reactions	IEP	Predicted GO
BP	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	IEP	Predicted GO
BP	GO:0000398	mRNA splicing, via spliceosome	IEP	Predicted GO
MF	GO:0001882	nucleoside binding	IEP	Predicted GO
MF	GO:0001883	purine nucleoside binding	IEP	Predicted GO
MF	GO:0003723	RNA binding	IEP	Predicted GO
MF	GO:0003779	actin binding	IEP	Predicted GO
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Predicted GO
MF	GO:0004197	cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004198	calcium-dependent cysteine-type endopeptidase activity	IEP	Predicted GO
MF	GO:0004399	histidinol dehydrogenase activity	IEP	Predicted GO
MF	GO:0004427	inorganic diphosphatase activity	IEP	Predicted GO
MF	GO:0004619	phosphoglycerate mutase activity	IEP	Predicted GO
MF	GO:0004645	phosphorylase activity	IEP	Predicted GO
MF	GO:0004672	protein kinase activity	IEP	Predicted GO
MF	GO:0004812	aminoacyl-tRNA ligase activity	IEP	Predicted GO
MF	GO:0004813	alanine-tRNA ligase activity	IEP	Predicted GO
MF	GO:0005525	GTP binding	IEP	Predicted GO
CC	GO:0005669	transcription factor TFIID complex	IEP	Predicted GO
BP	GO:0006006	glucose metabolic process	IEP	Predicted GO
BP	GO:0006007	glucose catabolic process	IEP	Predicted GO
BP	GO:0006419	alanyl-tRNA aminoacylation	IEP	Predicted GO
BP	GO:0006468	protein phosphorylation	IEP	Predicted GO
BP	GO:0006520	cellular amino acid metabolic process	IEP	Predicted GO
BP	GO:0006547	histidine metabolic process	IEP	Predicted GO
MF	GO:0008184	glycogen phosphorylase activity	IEP	Predicted GO
MF	GO:0009678	hydrogen-translocating pyrophosphatase activity	IEP	Predicted GO
BP	GO:0016310	phosphorylation	IEP	Predicted GO
MF	GO:0016462	pyrophosphatase activity	IEP	Predicted GO
MF	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	IEP	Predicted GO
MF	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	IEP	Predicted GO
MF	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	IEP	Predicted GO
MF	GO:0016868	intramolecular transferase activity, phosphotransferases	IEP	Predicted GO
MF	GO:0016875	ligase activity, forming carbon-oxygen bonds	IEP	Predicted GO
MF	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters	IEP	Predicted GO
MF	GO:0017069	snRNA binding	IEP	Predicted GO
MF	GO:0017070	U6 snRNA binding	IEP	Predicted GO
MF	GO:0019001	guanyl nucleotide binding	IEP	Predicted GO
BP	GO:0019320	hexose catabolic process	IEP	Predicted GO
MF	GO:0030145	manganese ion binding	IEP	Predicted GO
MF	GO:0030623	U5 snRNA binding	IEP	Predicted GO
MF	GO:0032549	ribonucleoside binding	IEP	Predicted GO
MF	GO:0032550	purine ribonucleoside binding	IEP	Predicted GO
MF	GO:0032561	guanyl ribonucleotide binding	IEP	Predicted GO
MF	GO:0033897	ribonuclease T2 activity	IEP	Predicted GO
BP	GO:0043038	amino acid activation	IEP	Predicted GO
BP	GO:0043039	tRNA aminoacylation	IEP	Predicted GO
BP	GO:0046365	monosaccharide catabolic process	IEP	Predicted GO
BP	GO:0052803	imidazole-containing compound metabolic process	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR003100	PAZ_dom	1920	2052
IPR005034	Dicer_dimerisation_dom	1043	1131
IPR001650	Helicase_C	864	976
IPR000999	RNase_III_dom	2464	2576
IPR000999	RNase_III_dom	2089	2387
IPR006935	Helicase/UvrB_N	342	576

External Links

No external refs found!

Kfl00265_0060 (kfl00265_0060_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation