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  5. Kfl00273_0150

Kfl00273_0150 (kfl00273_0150_v1.1)


Aliases : kfl00273_0150_v1.1

Description : (at3g22590 : 207.0) Encodes PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP), a homolog of human Paf1 Complex (Paf1C) subunit Parafibromin. Human Parafibromin assists in mediating output from the Wnt signaling pathway, and dysfunction of the encoding gene HRPT2 conditions specific cancer-related disease phenotypes. PHP resides in a ~670-kDa protein complex in nuclear extracts, and physically interacts with other known Paf1C-related proteins in vivo. Loss of PHP specifically conditioned accelerated phase transition from vegetative growth to flowering and resulted in misregulation of a very limited subset of genes that included the flowering repressor FLOWERING LOCUS C (FLC).; PLANT HOMOLOGOUS TO PARAFIBROMIN (PHP); CONTAINS InterPro DOMAIN/s: RNA polymerase II accessory factor, Cdc73 (InterPro:IPR007852); Has 502 Blast hits to 395 proteins in 198 species: Archae - 0; Bacteria - 0; Metazoa - 257; Fungi - 127; Plants - 42; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink). & (reliability: 414.0) & (original description: no original description)


Gene families : OG_42_0003860 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003860_tree

Sequence : coding (download), protein (download)


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00273_0150
Cluster HCCA clusters: Cluster_63

Target Alias Description ECC score Gene Family Method Actions
A4A49_34682 No alias protein cdc73-like protein 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source

No GO annotation available for this sequence
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Type GO Term Name Evidence Source
MF GO:0004888 transmembrane signaling receptor activity IEP Predicted GO
MF GO:0004970 ionotropic glutamate receptor activity IEP Predicted GO
MF GO:0005230 extracellular ligand-gated ion channel activity IEP Predicted GO
MF GO:0005488 binding IEP Predicted GO
CC GO:0005694 chromosome IEP Predicted GO
BP GO:0006479 protein methylation IEP Predicted GO
BP GO:0006914 autophagy IEP Predicted GO
MF GO:0008066 glutamate receptor activity IEP Predicted GO
MF GO:0008170 N-methyltransferase activity IEP Predicted GO
BP GO:0008213 protein alkylation IEP Predicted GO
MF GO:0008270 zinc ion binding IEP Predicted GO
MF GO:0008276 protein methyltransferase activity IEP Predicted GO
MF GO:0008757 S-adenosylmethionine-dependent methyltransferase activity IEP Predicted GO
BP GO:0009056 catabolic process IEP Predicted GO
MF GO:0015276 ligand-gated ion channel activity IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016226 iron-sulfur cluster assembly IEP Predicted GO
MF GO:0016278 lysine N-methyltransferase activity IEP Predicted GO
MF GO:0016279 protein-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0016569 covalent chromatin modification IEP Predicted GO
BP GO:0016570 histone modification IEP Predicted GO
BP GO:0016571 histone methylation IEP Predicted GO
BP GO:0018022 peptidyl-lysine methylation IEP Predicted GO
MF GO:0018024 histone-lysine N-methyltransferase activity IEP Predicted GO
BP GO:0018205 peptidyl-lysine modification IEP Predicted GO
MF GO:0022824 transmitter-gated ion channel activity IEP Predicted GO
MF GO:0022834 ligand-gated channel activity IEP Predicted GO
MF GO:0022835 transmitter-gated channel activity IEP Predicted GO
MF GO:0022836 gated channel activity IEP Predicted GO
MF GO:0022839 ion gated channel activity IEP Predicted GO
MF GO:0030594 neurotransmitter receptor activity IEP Predicted GO
BP GO:0031163 metallo-sulfur cluster assembly IEP Predicted GO
BP GO:0034968 histone lysine methylation IEP Predicted GO
MF GO:0038023 signaling receptor activity IEP Predicted GO
MF GO:0042054 histone methyltransferase activity IEP Predicted GO
MF GO:0043169 cation binding IEP Predicted GO
BP GO:0043414 macromolecule methylation IEP Predicted GO
BP GO:0044248 cellular catabolic process IEP Predicted GO
MF GO:0046872 metal ion binding IEP Predicted GO
MF GO:0046914 transition metal ion binding IEP Predicted GO
MF GO:0060089 molecular transducer activity IEP Predicted GO
BP GO:0061919 process utilizing autophagic mechanism IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
InterPro domains Description Start Stop
IPR031336 CDC73_C 289 439
IPR032041 Cdc73_N 2 155
No external refs found!