Kfl00280_0030 (kfl00280_0030_v1.1)

Aliases : kfl00280_0030_v1.1

Description : (at5g15410 : 444.0) 'defense, no death' gene (DND1) encodes a mutated cyclic nucleotide-gated cation channel; Same as CNGC2 (article ID 229): Cyclic nucleotide gated channel, activated by cAMP, conducts K+ and other monovalent cations but excludes Na+, does not contain the GYG amino acid sequence found in other channels with this conductivity profile. Conducts Ca2+ into cells which is linked to the generation of NO and the NO signaling pathway involved in the innate immune response to pathogens.; DEFENSE NO DEATH 1 (DND1); CONTAINS InterPro DOMAIN/s: Cyclic nucleotide-binding (InterPro:IPR000595), Cyclic nucleotide-binding-like (InterPro:IPR018490), RmlC-like jelly roll fold (InterPro:IPR014710); BEST Arabidopsis thaliana protein match is: cyclic nucleotide-gated cation channel 4 (TAIR:AT5G54250.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink). & (reliability: 888.0) & (original description: no original description)

Gene families : OG_42_0000108 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0000108_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00280_0030
Cluster	HCCA clusters: Cluster_49

Target	Alias	Description	ECC score	Gene Family Method
89324	No alias	cyclic nucleotide-binding transporter 1	0.02	Orthogroups_2024-Update
A4A49_15343	No alias	putative cyclic nucleotide-gated ion channel 17	0.01	Orthogroups_2024-Update
GRMZM2G023037	No alias	cyclic nucleotide gated channel 8	0.01	Orthogroups_2024-Update
Glyma.06G223800	No alias	cyclic nucleotide-gated channel 17	0.02	Orthogroups_2024-Update
Glyma.07G025000	No alias	cyclic nucleotide gated channel 19	0.02	Orthogroups_2024-Update
Glyma.09G168600	No alias	cyclic nucleotide-binding transporter 1	0.01	Orthogroups_2024-Update
HORVU6Hr1G083790.3	No alias	cyclic nucleotide-gated cation channel *(CNGC)	0.01	Orthogroups_2024-Update
LOC_Os05g42250	No alias	cyclic nucleotide-gated ion channel 2, putative, expressed	0.02	Orthogroups_2024-Update
PSME_00032968-RA	No alias	(at1g19780 : 461.0) member of Cyclic nucleotide gated...	0.02	Orthogroups_2024-Update
PSME_00037092-RA	No alias	(at5g54250 : 808.0) member of Cyclic nucleotide gated...	0.02	Orthogroups_2024-Update
PSME_00046136-RA	No alias	(at1g15990 : 435.0) member of Cyclic nucleotide gated...	0.02	Orthogroups_2024-Update
Potri.012G002200	No alias	cyclic nucleotide gated channel 1	0.02	Orthogroups_2024-Update
Potri.015G033900	No alias	cyclic nucleotide-binding transporter 1	0.01	Orthogroups_2024-Update
Pp1s68_102V6	No alias	cyclic nucleotide and calmodulin-regulated ion channel	0.02	Orthogroups_2024-Update
Seita.3G188100.1	No alias	cyclic nucleotide-gated cation channel *(CNGC)	0.02	Orthogroups_2024-Update
Sobic.006G237400.1	No alias	cyclic nucleotide-gated cation channel *(CNGC)	0.01	Orthogroups_2024-Update
Solyc05g050360	No alias	cyclic nucleotide gated channel 1 (AHRD V3.3 *** AT5G53130.1)	0.02	Orthogroups_2024-Update
Solyc12g010010	No alias	Cyclic nucleotide-gated ion channel, putative (AHRD V3.3...	0.02	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005215	transporter activity	None	Extended
MF	GO:0005216	ion channel activity	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
BP	GO:0006810	transport	None	Extended
BP	GO:0006811	ion transport	IEA	InterProScan predictions
BP	GO:0008150	biological_process	None	Extended
MF	GO:0015075	ion transmembrane transporter activity	None	Extended
MF	GO:0015267	channel activity	None	Extended
MF	GO:0015318	inorganic molecular entity transmembrane transporter activity	None	Extended
CC	GO:0016020	membrane	IEA	InterProScan predictions
MF	GO:0022803	passive transmembrane transporter activity	None	Extended
MF	GO:0022838	substrate-specific channel activity	None	Extended
MF	GO:0022857	transmembrane transporter activity	None	Extended
BP	GO:0051179	localization	None	Extended
BP	GO:0051234	establishment of localization	None	Extended
BP	GO:0055085	transmembrane transport	IEA	InterProScan predictions

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Type	GO Term	Name	Evidence	Source
CC	GO:0000145	exocyst	IEP	Predicted GO
BP	GO:0006887	exocytosis	IEP	Predicted GO
BP	GO:0006904	vesicle docking involved in exocytosis	IEP	Predicted GO
MF	GO:0008483	transaminase activity	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
CC	GO:0016021	integral component of membrane	IEP	Predicted GO
MF	GO:0016769	transferase activity, transferring nitrogenous groups	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
MF	GO:0019208	phosphatase regulator activity	IEP	Predicted GO
MF	GO:0019211	phosphatase activator activity	IEP	Predicted GO
BP	GO:0022406	membrane docking	IEP	Predicted GO
CC	GO:0031224	intrinsic component of membrane	IEP	Predicted GO
BP	GO:0032940	secretion by cell	IEP	Predicted GO
CC	GO:0044448	cell cortex part	IEP	Predicted GO
BP	GO:0046903	secretion	IEP	Predicted GO
BP	GO:0048278	vesicle docking	IEP	Predicted GO
BP	GO:0051640	organelle localization	IEP	Predicted GO
CC	GO:0099023	tethering complex	IEP	Predicted GO
BP	GO:0140029	exocytic process	IEP	Predicted GO
BP	GO:0140056	organelle localization by membrane tethering	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR005821	Ion_trans_dom	113	445

External Links

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Kfl00280_0030 (kfl00280_0030_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation