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  5. Kfl00326_0090

Kfl00326_0090 (kfl00326_0090_v1.1)


Aliases : kfl00326_0090_v1.1

Description : (q5z987|atr_orysa : 1092.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (at5g40820 : 1011.0) Encodes a Arabidopsis ortholog of the ATR protein kinase that is involved in a wide range of responses to DNA damage and plays a central role in cell-cycle regulation. Dominant loss of function alleles identified as suppressors of ALS also exhibit increased tolerance to aluminum. This may be due to the inhibition of terminal differentiation of the root apex upon exposure to Al.; Ataxia telangiectasia-mutated and RAD3-related (ATR); FUNCTIONS IN: protein serine/threonine kinase activity, inositol or phosphatidylinositol kinase activity, binding, phosphotransferase activity, alcohol group as acceptor; INVOLVED IN: in 9 processes; EXPRESSED IN: 10 plant structures; EXPRESSED DURING: 6 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), UME (InterPro:IPR012993), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), Armadillo-type fold (InterPro:IPR016024), PIK-related kinase (InterPro:IPR014009), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: ataxia-telangiectasia mutated (TAIR:AT3G48190.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (reliability: 2022.0) & (original description: no original description)


Gene families : OG_42_0007184 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0007184_tree

Sequence : coding (download), protein (download)


Attention: This gene has low abundance.


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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00326_0090
Cluster HCCA clusters: Cluster_82

Target Alias Description ECC score Gene Family Method Actions
Cre10.g467200 No alias Ataxia telangiectasia-mutated and RAD3-related 0.02 Orthogroups_2024-Update
Glyma.10G284200 No alias Ataxia telangiectasia-mutated and RAD3-related 0.02 Orthogroups_2024-Update
Pp1s77_262V6 No alias serine threonine-protein kinase 0.02 Orthogroups_2024-Update
Sobic.010G269800.1 No alias kinase component *(ATR) of ATR-ATRIP DNA damage sensor complex 0.02 Orthogroups_2024-Update
evm.model.tig00020537.66 No alias (at5g40820 : 318.0) Encodes a Arabidopsis ortholog of... 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0004674 protein serine/threonine kinase activity IEA InterProScan predictions
MF GO:0005515 protein binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
CC GO:0000151 ubiquitin ligase complex IEP Predicted GO
CC GO:0000152 nuclear ubiquitin ligase complex IEP Predicted GO
MF GO:0003872 6-phosphofructokinase activity IEP Predicted GO
MF GO:0003899 DNA-directed 5'-3' RNA polymerase activity IEP Predicted GO
MF GO:0004146 dihydrofolate reductase activity IEP Predicted GO
MF GO:0004427 inorganic diphosphatase activity IEP Predicted GO
MF GO:0004576 oligosaccharyl transferase activity IEP Predicted GO
MF GO:0004645 phosphorylase activity IEP Predicted GO
MF GO:0004812 aminoacyl-tRNA ligase activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
CC GO:0005680 anaphase-promoting complex IEP Predicted GO
BP GO:0005975 carbohydrate metabolic process IEP Predicted GO
BP GO:0006082 organic acid metabolic process IEP Predicted GO
BP GO:0006139 nucleobase-containing compound metabolic process IEP Predicted GO
BP GO:0006298 mismatch repair IEP Predicted GO
BP GO:0006351 transcription, DNA-templated IEP Predicted GO
BP GO:0006418 tRNA aminoacylation for protein translation IEP Predicted GO
BP GO:0006725 cellular aromatic compound metabolic process IEP Predicted GO
BP GO:0006732 coenzyme metabolic process IEP Predicted GO
BP GO:0006760 folic acid-containing compound metabolic process IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008152 metabolic process IEP Predicted GO
MF GO:0008184 glycogen phosphorylase activity IEP Predicted GO
CC GO:0008250 oligosaccharyltransferase complex IEP Predicted GO
MF GO:0008443 phosphofructokinase activity IEP Predicted GO
BP GO:0009108 coenzyme biosynthetic process IEP Predicted GO
BP GO:0009141 nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009144 purine nucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009199 ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009205 purine ribonucleoside triphosphate metabolic process IEP Predicted GO
BP GO:0009396 folic acid-containing compound biosynthetic process IEP Predicted GO
MF GO:0009678 hydrogen-translocating pyrophosphatase activity IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
BP GO:0016070 RNA metabolic process IEP Predicted GO
BP GO:0016192 vesicle-mediated transport IEP Predicted GO
MF GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IEP Predicted GO
MF GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor IEP Predicted GO
MF GO:0016758 transferase activity, transferring hexosyl groups IEP Predicted GO
MF GO:0016779 nucleotidyltransferase activity IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016875 ligase activity, forming carbon-oxygen bonds IEP Predicted GO
MF GO:0017056 structural constituent of nuclear pore IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
BP GO:0018130 heterocycle biosynthetic process IEP Predicted GO
MF GO:0019200 carbohydrate kinase activity IEP Predicted GO
BP GO:0019321 pentose metabolic process IEP Predicted GO
BP GO:0019438 aromatic compound biosynthetic process IEP Predicted GO
BP GO:0019566 arabinose metabolic process IEP Predicted GO
BP GO:0019752 carboxylic acid metabolic process IEP Predicted GO
CC GO:0030117 membrane coat IEP Predicted GO
CC GO:0030119 AP-type membrane coat adaptor complex IEP Predicted GO
CC GO:0030126 COPI vesicle coat IEP Predicted GO
CC GO:0030131 clathrin adaptor complex IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0030983 mismatched DNA binding IEP Predicted GO
CC GO:0031461 cullin-RING ubiquitin ligase complex IEP Predicted GO
BP GO:0032324 molybdopterin cofactor biosynthetic process IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
MF GO:0034062 5'-3' RNA polymerase activity IEP Predicted GO
CC GO:0034998 oligosaccharyltransferase I complex IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
BP GO:0042278 purine nucleoside metabolic process IEP Predicted GO
BP GO:0042558 pteridine-containing compound metabolic process IEP Predicted GO
BP GO:0042559 pteridine-containing compound biosynthetic process IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
BP GO:0043038 amino acid activation IEP Predicted GO
BP GO:0043039 tRNA aminoacylation IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
BP GO:0043436 oxoacid metabolic process IEP Predicted GO
BP GO:0043545 molybdopterin cofactor metabolic process IEP Predicted GO
BP GO:0044238 primary metabolic process IEP Predicted GO
BP GO:0044281 small molecule metabolic process IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
BP GO:0046039 GTP metabolic process IEP Predicted GO
BP GO:0046128 purine ribonucleoside metabolic process IEP Predicted GO
BP GO:0046373 L-arabinose metabolic process IEP Predicted GO
BP GO:0046483 heterocycle metabolic process IEP Predicted GO
MF GO:0046556 alpha-L-arabinofuranosidase activity IEP Predicted GO
BP GO:0046653 tetrahydrofolate metabolic process IEP Predicted GO
BP GO:0046654 tetrahydrofolate biosynthetic process IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0051186 cofactor metabolic process IEP Predicted GO
BP GO:0051188 cofactor biosynthetic process IEP Predicted GO
BP GO:0051189 prosthetic group metabolic process IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
MF GO:0070569 uridylyltransferase activity IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071704 organic substance metabolic process IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0097659 nucleic acid-templated transcription IEP Predicted GO
MF GO:0097747 RNA polymerase activity IEP Predicted GO
MF GO:0140098 catalytic activity, acting on RNA IEP Predicted GO
BP GO:1901068 guanosine-containing compound metabolic process IEP Predicted GO
BP GO:1901360 organic cyclic compound metabolic process IEP Predicted GO
BP GO:1901362 organic cyclic compound biosynthetic process IEP Predicted GO
CC GO:1990234 transferase complex IEP Predicted GO
InterPro domains Description Start Stop
IPR012993 UME 1081 1182
IPR003151 PIK-rel_kinase_FAT 1781 2189
IPR003152 FATC_dom 2581 2612
IPR000403 PI3/4_kinase_cat_dom 2395 2541
No external refs found!