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  5. Kfl00331_0140

Kfl00331_0140 (kfl00331_0140_v1.1)


Aliases : kfl00331_0140_v1.1

Description : (p09114|ilv2_tobac : 884.0) Acetolactate synthase 2, chloroplast precursor (EC 2.2.1.6) (Acetolactate synthase II) (Acetohydroxy-acid synthase II) (ALS II) - Nicotiana tabacum (Common tobacco) & (at3g48560 : 857.0) Catalyzes the formation of acetolactate from pyruvate, the first step in valine and isoleucine biosynthesis. Requires FAD, thiamine pyrophosphate and Mg. Inhibited by the sulphonylurea herbicide, chlorsulphuron, and the imidazolinone herbicide, imazapyr. The obtained crystal structure of acetohydroxyacid synthase AHAS, EC 2.2.1.6)in complex with herbicides of the sulphonylurea and imidazolinone family reveals the molecular basis for substrate/inhibitor binding.; chlorsulfuron/imidazolinone resistant 1 (CSR1); FUNCTIONS IN: acetolactate synthase activity, pyruvate decarboxylase activity; INVOLVED IN: branched chain family amino acid biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TPP-binding enzyme, conserved site (InterPro:IPR000399), Thiamine pyrophosphate enzyme, central domain (InterPro:IPR012000), Acetolactate synthase, large subunit, biosynthetic (InterPro:IPR012846), Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain (InterPro:IPR012001), Thiamine pyrophosphate enzyme, C-terminal TPP-binding (InterPro:IPR011766); BEST Arabidopsis thaliana protein match is: Thiamine pyrophosphate dependent pyruvate decarboxylase family protein (TAIR:AT5G17380.1); Has 30963 Blast hits to 30605 proteins in 2694 species: Archae - 488; Bacteria - 17421; Metazoa - 266; Fungi - 871; Plants - 599; Viruses - 25; Other Eukaryotes - 11293 (source: NCBI BLink). & (reliability: 1714.0) & (original description: no original description)


Gene families : OG_42_0003559 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0003559_tree

Sequence : coding (download), protein (download)


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Type Description Actions
Neighborhood Klebsormidium release: Kfl00331_0140
Cluster HCCA clusters: Cluster_48


Type GO Term Name Evidence Source
MF GO:0000287 magnesium ion binding IEA InterProScan predictions
MF GO:0003824 catalytic activity IEA InterProScan predictions
MF GO:0030976 thiamine pyrophosphate binding IEA InterProScan predictions
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Type GO Term Name Evidence Source
BP GO:0006790 sulfur compound metabolic process IEP Predicted GO
BP GO:0010215 cellulose microfibril organization IEP Predicted GO
BP GO:0016043 cellular component organization IEP Predicted GO
BP GO:0016049 cell growth IEP Predicted GO
BP GO:0016226 iron-sulfur cluster assembly IEP Predicted GO
BP GO:0030198 extracellular matrix organization IEP Predicted GO
BP GO:0031163 metallo-sulfur cluster assembly IEP Predicted GO
CC GO:0031225 anchored component of membrane IEP Predicted GO
BP GO:0040007 growth IEP Predicted GO
BP GO:0043062 extracellular structure organization IEP Predicted GO
MF GO:0046914 transition metal ion binding IEP Predicted GO
BP GO:0071840 cellular component organization or biogenesis IEP Predicted GO
InterPro domains Description Start Stop
IPR011766 TPP_enzyme-bd_C 537 692
IPR012001 Thiamin_PyroP_enz_TPP-bd_dom 149 311
IPR012000 Thiamin_PyroP_enz_cen_dom 341 472
No external refs found!