Kfl00347_0050 (kfl00347_0050_v1.1)

Aliases : kfl00347_0050_v1.1

Description : (at3g47450 : 254.0) Encodes a protein with similarity to the bacterial YqeH GTPase required for proper ribosome assembly. In Arabidopsis, mutant analyses show that this protein regulates growth and hormonal signaling in plants. It also attenuates oxidative stress and reactive oxygen species (ROS). It also seems to be involved in regulating leaf senescence and cell death. This gene product is also involved in nitric oxide biosynthesis in response to ABA but not exogenous H2O2. This protein also appears to be required for proper plastid biogenesis. Levels of several plastid-localized proteins, including RBCL, ClpP1, and the MEP biosynthesis enzymes DXS and DXR are altered in rif1-1 mutants. This protein was originally characterized as a mitrochondrial-localized nitric oxide synthase, but, the synthase activity was later disproven. In addition, new studies with GFP fusion proteins and chloroplast import assays suggest that this protein is found in chloroplasts.; NO ASSOCIATED 1 (NOA1); FUNCTIONS IN: GTPase activity; INVOLVED IN: in 8 processes; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; BEST Arabidopsis thaliana protein match is: P-loop containing nucleoside triphosphate hydrolases superfamily protein (TAIR:AT3G57180.1); Has 1589 Blast hits to 1531 proteins in 754 species: Archae - 6; Bacteria - 1199; Metazoa - 159; Fungi - 35; Plants - 109; Viruses - 0; Other Eukaryotes - 81 (source: NCBI BLink). & (q6ypg5|nos_orysa : 254.0) Putative nitric-oxide synthase (EC 1.14.13.39) - Oryza sativa (Rice) & (reliability: 508.0) & (original description: no original description)

Gene families : OG_42_0006185 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0006185_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00347_0050
Cluster	HCCA clusters: Cluster_55

Target	Alias	Description	ECC score	Gene Family Method
Bradi3g00690	No alias	P-loop containing nucleoside triphosphate hydrolases...	0.02	Orthogroups_2024-Update
Cre09.g400550	No alias	P-loop containing nucleoside triphosphate hydrolases...	0.02	Orthogroups_2024-Update
Seita.1G003800.1	No alias	Unknown function	0.02	Orthogroups_2024-Update
Sobic.004G003900.1	No alias	Unknown function	0.01	Orthogroups_2024-Update
evm.model.tig00022080.6	No alias	(at3g47450 : 177.0) Encodes a protein with similarity to...	0.01	Orthogroups_2024-Update

Type	GO Term	Name	Evidence	Source
MF	GO:0000166	nucleotide binding	None	Extended
MF	GO:0001882	nucleoside binding	None	Extended
MF	GO:0001883	purine nucleoside binding	None	Extended
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005525	GTP binding	IEA	InterProScan predictions
MF	GO:0017076	purine nucleotide binding	None	Extended
MF	GO:0019001	guanyl nucleotide binding	None	Extended
MF	GO:0032549	ribonucleoside binding	None	Extended
MF	GO:0032550	purine ribonucleoside binding	None	Extended
MF	GO:0032553	ribonucleotide binding	None	Extended
MF	GO:0032555	purine ribonucleotide binding	None	Extended
MF	GO:0032561	guanyl ribonucleotide binding	None	Extended
MF	GO:0035639	purine ribonucleoside triphosphate binding	None	Extended
MF	GO:0036094	small molecule binding	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043168	anion binding	None	Extended
MF	GO:0097159	organic cyclic compound binding	None	Extended
MF	GO:0097367	carbohydrate derivative binding	None	Extended
MF	GO:1901265	nucleoside phosphate binding	None	Extended
MF	GO:1901363	heterocyclic compound binding	None	Extended

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Type	GO Term	Name	Evidence	Source
BP	GO:0000226	microtubule cytoskeleton organization	IEP	Predicted GO
MF	GO:0004470	malic enzyme activity	IEP	Predicted GO
MF	GO:0004471	malate dehydrogenase (decarboxylating) (NAD+) activity	IEP	Predicted GO
MF	GO:0004518	nuclease activity	IEP	Predicted GO
MF	GO:0004525	ribonuclease III activity	IEP	Predicted GO
MF	GO:0004540	ribonuclease activity	IEP	Predicted GO
CC	GO:0005634	nucleus	IEP	Predicted GO
CC	GO:0005815	microtubule organizing center	IEP	Predicted GO
BP	GO:0006396	RNA processing	IEP	Predicted GO
BP	GO:0007010	cytoskeleton organization	IEP	Predicted GO
BP	GO:0007059	chromosome segregation	IEP	Predicted GO
MF	GO:0008641	ubiquitin-like modifier activating enzyme activity	IEP	Predicted GO
MF	GO:0009982	pseudouridine synthase activity	IEP	Predicted GO
BP	GO:0016070	RNA metabolic process	IEP	Predicted GO
MF	GO:0016615	malate dehydrogenase activity	IEP	Predicted GO
MF	GO:0016877	ligase activity, forming carbon-sulfur bonds	IEP	Predicted GO
BP	GO:0022613	ribonucleoprotein complex biogenesis	IEP	Predicted GO
MF	GO:0032296	double-stranded RNA-specific ribonuclease activity	IEP	Predicted GO
BP	GO:0034453	microtubule anchoring	IEP	Predicted GO
BP	GO:0042254	ribosome biogenesis	IEP	Predicted GO
CC	GO:0043226	organelle	IEP	Predicted GO
CC	GO:0043227	membrane-bounded organelle	IEP	Predicted GO
CC	GO:0043229	intracellular organelle	IEP	Predicted GO
CC	GO:0043231	intracellular membrane-bounded organelle	IEP	Predicted GO
BP	GO:0051301	cell division	IEP	Predicted GO
BP	GO:0090304	nucleic acid metabolic process	IEP	Predicted GO
MF	GO:0140098	catalytic activity, acting on RNA	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR006073	GTP_binding_domain	188	255

External Links

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Kfl00347_0050 (kfl00347_0050_v1.1)

Expression Profile

Co-expression Networks

Expression Context Conservation (ECC)

Functional Annotation