Kfl00356_0080 (kfl00356_0080_v1.1)


Aliases : kfl00356_0080_v1.1

Description : (at1g50030 : 2690.0) Related to TOR proteins from yeast and mammals, regulators of cell growth in response to nutrient availability. TOR proteins belong to the family of phosphatidylinositol 3-kinase and are targets of the antiproliferative drug rapamycin. AtTOR binds the yeast FKBP12 protein in the presence of Rapamycin, is involved in embryogenesis and is expressed in embryos, endosperm and meristems.; target of rapamycin (TOR); FUNCTIONS IN: protein binding, 1-phosphatidylinositol-3-kinase activity; INVOLVED IN: embryo development ending in seed dormancy; LOCATED IN: chloroplast; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Phosphatidylinositol 3-/4-kinase, catalytic (InterPro:IPR000403), FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding (InterPro:IPR009076), Armadillo-like helical (InterPro:IPR011989), Protein kinase-like domain (InterPro:IPR011009), PIK-related kinase, FAT (InterPro:IPR003151), PIK-related kinase (InterPro:IPR014009), Armadillo-type fold (InterPro:IPR016024), Phosphatidylinositol 3/4-kinase, conserved site (InterPro:IPR018936), PIK-related kinase, FATC (InterPro:IPR003152); BEST Arabidopsis thaliana protein match is: Ataxia telangiectasia-mutated and RAD3-related (TAIR:AT5G40820.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink). & (q5z987|atr_orysa : 183.0) Serine/threonine-protein kinase ATR (EC 2.7.11.1) - Oryza sativa (Rice) & (reliability: 5380.0) & (original description: no original description)


Gene families : OG_42_0004193 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0004193_tree

Sequence : coding (download), protein (download)


Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.


Type Description Actions
Neighborhood Klebsormidium release: Kfl00356_0080
Cluster HCCA clusters: Cluster_101

Target Alias Description ECC score Gene Family Method Actions
Bradi2g28007 No alias target of rapamycin 0.03 Orthogroups_2024-Update
Glyma.01G241300 No alias target of rapamycin 0.02 Orthogroups_2024-Update
Potri.001G289200 No alias target of rapamycin 0.01 Orthogroups_2024-Update
Seita.3G273900.1 No alias phosphatidylinositol kinase component *(TOR) of TORC complex 0.01 Orthogroups_2024-Update
Solyc01g106770 No alias Serine/threonine-protein kinase (AHRD V3.3 *** A0A0K0XR78_TOBAC) 0.02 Orthogroups_2024-Update

Type GO Term Name Evidence Source
MF GO:0005515 protein binding IEA InterProScan predictions
MF GO:0044877 protein-containing complex binding IEA InterProScan predictions
Type GO Term Name Evidence Source
CC GO:0000145 exocyst IEP Predicted GO
MF GO:0000155 phosphorelay sensor kinase activity IEP Predicted GO
MF GO:0000166 nucleotide binding IEP Predicted GO
MF GO:0003824 catalytic activity IEP Predicted GO
MF GO:0003993 acid phosphatase activity IEP Predicted GO
MF GO:0004470 malic enzyme activity IEP Predicted GO
MF GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity IEP Predicted GO
MF GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEP Predicted GO
MF GO:0004672 protein kinase activity IEP Predicted GO
MF GO:0004673 protein histidine kinase activity IEP Predicted GO
MF GO:0005049 nuclear export signal receptor activity IEP Predicted GO
MF GO:0005215 transporter activity IEP Predicted GO
MF GO:0005216 ion channel activity IEP Predicted GO
MF GO:0005524 ATP binding IEP Predicted GO
CC GO:0005575 cellular_component IEP Predicted GO
CC GO:0005643 nuclear pore IEP Predicted GO
BP GO:0006468 protein phosphorylation IEP Predicted GO
BP GO:0006810 transport IEP Predicted GO
BP GO:0006886 intracellular protein transport IEP Predicted GO
BP GO:0006904 vesicle docking involved in exocytosis IEP Predicted GO
BP GO:0008104 protein localization IEP Predicted GO
MF GO:0008144 drug binding IEP Predicted GO
BP GO:0008150 biological_process IEP Predicted GO
MF GO:0008536 Ran GTPase binding IEP Predicted GO
MF GO:0009055 electron transfer activity IEP Predicted GO
BP GO:0015031 protein transport IEP Predicted GO
MF GO:0015075 ion transmembrane transporter activity IEP Predicted GO
MF GO:0015079 potassium ion transmembrane transporter activity IEP Predicted GO
MF GO:0015267 channel activity IEP Predicted GO
MF GO:0015318 inorganic molecular entity transmembrane transporter activity IEP Predicted GO
MF GO:0015399 primary active transmembrane transporter activity IEP Predicted GO
MF GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity IEP Predicted GO
BP GO:0015833 peptide transport IEP Predicted GO
CC GO:0016020 membrane IEP Predicted GO
MF GO:0016301 kinase activity IEP Predicted GO
MF GO:0016462 pyrophosphatase activity IEP Predicted GO
MF GO:0016615 malate dehydrogenase activity IEP Predicted GO
MF GO:0016773 phosphotransferase activity, alcohol group as acceptor IEP Predicted GO
MF GO:0016775 phosphotransferase activity, nitrogenous group as acceptor IEP Predicted GO
MF GO:0016787 hydrolase activity IEP Predicted GO
MF GO:0016788 hydrolase activity, acting on ester bonds IEP Predicted GO
MF GO:0016791 phosphatase activity IEP Predicted GO
MF GO:0016798 hydrolase activity, acting on glycosyl bonds IEP Predicted GO
MF GO:0016817 hydrolase activity, acting on acid anhydrides IEP Predicted GO
MF GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEP Predicted GO
MF GO:0016887 ATPase activity IEP Predicted GO
MF GO:0017016 Ras GTPase binding IEP Predicted GO
MF GO:0017076 purine nucleotide binding IEP Predicted GO
MF GO:0017111 nucleoside-triphosphatase activity IEP Predicted GO
MF GO:0019899 enzyme binding IEP Predicted GO
BP GO:0022406 membrane docking IEP Predicted GO
MF GO:0022803 passive transmembrane transporter activity IEP Predicted GO
MF GO:0022838 substrate-specific channel activity IEP Predicted GO
MF GO:0022857 transmembrane transporter activity IEP Predicted GO
BP GO:0030001 metal ion transport IEP Predicted GO
CC GO:0030014 CCR4-NOT complex IEP Predicted GO
MF GO:0030554 adenyl nucleotide binding IEP Predicted GO
MF GO:0031267 small GTPase binding IEP Predicted GO
MF GO:0032553 ribonucleotide binding IEP Predicted GO
MF GO:0032555 purine ribonucleotide binding IEP Predicted GO
MF GO:0032559 adenyl ribonucleotide binding IEP Predicted GO
BP GO:0033036 macromolecule localization IEP Predicted GO
MF GO:0035639 purine ribonucleoside triphosphate binding IEP Predicted GO
MF GO:0036094 small molecule binding IEP Predicted GO
MF GO:0042578 phosphoric ester hydrolase activity IEP Predicted GO
MF GO:0042623 ATPase activity, coupled IEP Predicted GO
MF GO:0042626 ATPase activity, coupled to transmembrane movement of substances IEP Predicted GO
BP GO:0042886 amide transport IEP Predicted GO
MF GO:0043167 ion binding IEP Predicted GO
MF GO:0043168 anion binding IEP Predicted GO
MF GO:0043492 ATPase activity, coupled to movement of substances IEP Predicted GO
CC GO:0044448 cell cortex part IEP Predicted GO
BP GO:0045184 establishment of protein localization IEP Predicted GO
MF GO:0046873 metal ion transmembrane transporter activity IEP Predicted GO
BP GO:0046907 intracellular transport IEP Predicted GO
BP GO:0048278 vesicle docking IEP Predicted GO
MF GO:0051020 GTPase binding IEP Predicted GO
BP GO:0051179 localization IEP Predicted GO
BP GO:0051234 establishment of localization IEP Predicted GO
MF GO:0051536 iron-sulfur cluster binding IEP Predicted GO
MF GO:0051540 metal cluster binding IEP Predicted GO
BP GO:0051640 organelle localization IEP Predicted GO
BP GO:0051641 cellular localization IEP Predicted GO
BP GO:0051649 establishment of localization in cell IEP Predicted GO
BP GO:0055085 transmembrane transport IEP Predicted GO
BP GO:0071702 organic substance transport IEP Predicted GO
BP GO:0071705 nitrogen compound transport IEP Predicted GO
BP GO:0071805 potassium ion transmembrane transport IEP Predicted GO
MF GO:0097159 organic cyclic compound binding IEP Predicted GO
MF GO:0097367 carbohydrate derivative binding IEP Predicted GO
BP GO:0140029 exocytic process IEP Predicted GO
BP GO:0140056 organelle localization by membrane tethering IEP Predicted GO
MF GO:0140096 catalytic activity, acting on a protein IEP Predicted GO
MF GO:0140104 molecular carrier activity IEP Predicted GO
MF GO:0140142 nucleocytoplasmic carrier activity IEP Predicted GO
MF GO:1901265 nucleoside phosphate binding IEP Predicted GO
MF GO:1901363 heterocyclic compound binding IEP Predicted GO
InterPro domains Description Start Stop
IPR009076 FRB_dom 1894 1993
IPR003151 PIK-rel_kinase_FAT 1440 1787
IPR000403 PI3/4_kinase_cat_dom 2062 2310
IPR024585 DUF3385_TOR 765 940
No external refs found!