Kfl00373_0160 (kfl00373_0160_v1.1)

Aliases : kfl00373_0160_v1.1

Description : (at1g77300 : 298.0) Encodes a protein with histone lysine N-methyltransferase activity required specifically for the trimethylation of H3-K4 in FLC chromatin (and not in H3-K36 dimethylation). Acts as an inhibitor of flowering specifically involved in the autonomous promotion pathway. EFS also regulates the expression of genes involved in carotenoid biosynthesis.Modification of histone methylation at the CRTISO locus reduces transcript levels 90%. The increased shoot branching seen in some EFS mutants is likely due to the carotenoid biosynthesis defect having an effect on stringolactones.Required for ovule, embryo sac, anther and pollen development.; EARLY FLOWERING IN SHORT DAYS (EFS); FUNCTIONS IN: histone methyltransferase activity (H3-K4 specific); INVOLVED IN: in 10 processes; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: SET domain (InterPro:IPR001214), Post-SET domain (InterPro:IPR003616), AWS (InterPro:IPR006560), Zinc finger, CW-type (InterPro:IPR011124); BEST Arabidopsis thaliana protein match is: SET domain group 26 (TAIR:AT1G76710.2); Has 6227 Blast hits to 6009 proteins in 532 species: Archae - 3; Bacteria - 662; Metazoa - 2557; Fungi - 556; Plants - 1120; Viruses - 3; Other Eukaryotes - 1326 (source: NCBI BLink). & (reliability: 596.0) & (original description: no original description)

Gene families : OG_42_0005281 (Orthogroups_2024-Update) Phylogenetic Tree(s): OG0005281_tree

Sequence : coding (download), protein (download)

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Note:Only the main profile, including all conditions, is shown. Additional statistics and tissue specific profiles are available here.

Type	Description	Actions
Neighborhood	Klebsormidium release: Kfl00373_0160
Cluster	HCCA clusters: Cluster_132

Type	GO Term	Name	Evidence	Source
MF	GO:0003674	molecular_function	None	Extended
MF	GO:0003824	catalytic activity	None	Extended
MF	GO:0005488	binding	None	Extended
MF	GO:0005515	protein binding	IEA	InterProScan predictions
CC	GO:0005575	cellular_component	None	Extended
CC	GO:0005694	chromosome	IEA	InterProScan predictions
BP	GO:0006325	chromatin organization	None	Extended
BP	GO:0006355	regulation of transcription, DNA-templated	IEA	InterProScan predictions
BP	GO:0006464	cellular protein modification process	None	Extended
BP	GO:0006479	protein methylation	None	Extended
BP	GO:0006807	nitrogen compound metabolic process	None	Extended
BP	GO:0008150	biological_process	None	Extended
BP	GO:0008152	metabolic process	None	Extended
MF	GO:0008168	methyltransferase activity	None	Extended
MF	GO:0008170	N-methyltransferase activity	None	Extended
BP	GO:0008213	protein alkylation	None	Extended
MF	GO:0008270	zinc ion binding	IEA	InterProScan predictions
MF	GO:0008276	protein methyltransferase activity	None	Extended
MF	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	None	Extended
BP	GO:0009889	regulation of biosynthetic process	None	Extended
BP	GO:0009987	cellular process	None	Extended
BP	GO:0010468	regulation of gene expression	None	Extended
BP	GO:0010556	regulation of macromolecule biosynthetic process	None	Extended
BP	GO:0016043	cellular component organization	None	Extended
MF	GO:0016278	lysine N-methyltransferase activity	None	Extended
MF	GO:0016279	protein-lysine N-methyltransferase activity	None	Extended
BP	GO:0016569	covalent chromatin modification	None	Extended
BP	GO:0016570	histone modification	None	Extended
BP	GO:0016571	histone methylation	None	Extended
MF	GO:0016740	transferase activity	None	Extended
MF	GO:0016741	transferase activity, transferring one-carbon groups	None	Extended
BP	GO:0018022	peptidyl-lysine methylation	None	Extended
MF	GO:0018024	histone-lysine N-methyltransferase activity	IEA	InterProScan predictions
BP	GO:0018193	peptidyl-amino acid modification	None	Extended
BP	GO:0018205	peptidyl-lysine modification	None	Extended
BP	GO:0019219	regulation of nucleobase-containing compound metabolic process	None	Extended
BP	GO:0019222	regulation of metabolic process	None	Extended
BP	GO:0019538	protein metabolic process	None	Extended
BP	GO:0031323	regulation of cellular metabolic process	None	Extended
BP	GO:0031326	regulation of cellular biosynthetic process	None	Extended
BP	GO:0032259	methylation	None	Extended
BP	GO:0034968	histone lysine methylation	IEA	InterProScan predictions
BP	GO:0036211	protein modification process	None	Extended
MF	GO:0042054	histone methyltransferase activity	None	Extended
MF	GO:0043167	ion binding	None	Extended
MF	GO:0043169	cation binding	None	Extended
BP	GO:0043170	macromolecule metabolic process	None	Extended
CC	GO:0043226	organelle	None	Extended
CC	GO:0043228	non-membrane-bounded organelle	None	Extended
CC	GO:0043229	intracellular organelle	None	Extended
CC	GO:0043232	intracellular non-membrane-bounded organelle	None	Extended
BP	GO:0043412	macromolecule modification	None	Extended
BP	GO:0043414	macromolecule methylation	None	Extended
BP	GO:0044237	cellular metabolic process	None	Extended
BP	GO:0044238	primary metabolic process	None	Extended
BP	GO:0044260	cellular macromolecule metabolic process	None	Extended
BP	GO:0044267	cellular protein metabolic process	None	Extended
CC	GO:0044424	intracellular part	None	Extended
CC	GO:0044464	cell part	None	Extended
MF	GO:0046872	metal ion binding	None	Extended
MF	GO:0046914	transition metal ion binding	None	Extended
BP	GO:0050789	regulation of biological process	None	Extended
BP	GO:0050794	regulation of cellular process	None	Extended
BP	GO:0051171	regulation of nitrogen compound metabolic process	None	Extended
BP	GO:0051252	regulation of RNA metabolic process	None	Extended
BP	GO:0060255	regulation of macromolecule metabolic process	None	Extended
BP	GO:0065007	biological regulation	None	Extended
BP	GO:0071704	organic substance metabolic process	None	Extended
BP	GO:0071840	cellular component organization or biogenesis	None	Extended
BP	GO:0080090	regulation of primary metabolic process	None	Extended
MF	GO:0140096	catalytic activity, acting on a protein	None	Extended
BP	GO:1901564	organonitrogen compound metabolic process	None	Extended
BP	GO:1903506	regulation of nucleic acid-templated transcription	None	Extended
BP	GO:2000112	regulation of cellular macromolecule biosynthetic process	None	Extended
BP	GO:2001141	regulation of RNA biosynthetic process	None	Extended

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Type	GO Term	Name	Evidence	Source
CC	GO:0000439	transcription factor TFIIH core complex	IEP	Predicted GO
MF	GO:0001671	ATPase activator activity	IEP	Predicted GO
MF	GO:0003700	DNA-binding transcription factor activity	IEP	Predicted GO
MF	GO:0004176	ATP-dependent peptidase activity	IEP	Predicted GO
MF	GO:0004527	exonuclease activity	IEP	Predicted GO
MF	GO:0005085	guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005088	Ras guanyl-nucleotide exchange factor activity	IEP	Predicted GO
MF	GO:0005089	Rho guanyl-nucleotide exchange factor activity	IEP	Predicted GO
CC	GO:0005667	transcription factor complex	IEP	Predicted GO
BP	GO:0006281	DNA repair	IEP	Predicted GO
BP	GO:0006289	nucleotide-excision repair	IEP	Predicted GO
BP	GO:0006508	proteolysis	IEP	Predicted GO
BP	GO:0006914	autophagy	IEP	Predicted GO
BP	GO:0006950	response to stress	IEP	Predicted GO
BP	GO:0006974	cellular response to DNA damage stimulus	IEP	Predicted GO
MF	GO:0008047	enzyme activator activity	IEP	Predicted GO
MF	GO:0008233	peptidase activity	IEP	Predicted GO
MF	GO:0008408	3'-5' exonuclease activity	IEP	Predicted GO
BP	GO:0016579	protein deubiquitination	IEP	Predicted GO
MF	GO:0017016	Ras GTPase binding	IEP	Predicted GO
MF	GO:0017048	Rho GTPase binding	IEP	Predicted GO
MF	GO:0031267	small GTPase binding	IEP	Predicted GO
BP	GO:0033554	cellular response to stress	IEP	Predicted GO
CC	GO:0044798	nuclear transcription factor complex	IEP	Predicted GO
BP	GO:0050896	response to stimulus	IEP	Predicted GO
MF	GO:0051020	GTPase binding	IEP	Predicted GO
BP	GO:0051716	cellular response to stimulus	IEP	Predicted GO
MF	GO:0060589	nucleoside-triphosphatase regulator activity	IEP	Predicted GO
MF	GO:0060590	ATPase regulator activity	IEP	Predicted GO
BP	GO:0061919	process utilizing autophagic mechanism	IEP	Predicted GO
MF	GO:0070011	peptidase activity, acting on L-amino acid peptides	IEP	Predicted GO
BP	GO:0070646	protein modification by small protein removal	IEP	Predicted GO
MF	GO:0071949	FAD binding	IEP	Predicted GO
CC	GO:0090575	RNA polymerase II transcription factor complex	IEP	Predicted GO
MF	GO:0098772	molecular function regulator	IEP	Predicted GO
MF	GO:0140110	transcription regulator activity	IEP	Predicted GO

InterPro domains	Description	Start	Stop
IPR011124	Znf_CW	18	63
IPR013257	SRI	1210	1294
IPR001214	SET_dom	205	311

External Links

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Kfl00373_0160 (kfl00373_0160_v1.1)

Expression Profile

Co-expression Networks

Functional Annotation